-
1
-
-
0037116641
-
Prevalence of the metabolic syndrome among US adults: Findings from the Third National Health and Nutrition Examination Survey
-
E.S. Ford, W.H. Giles, and W.H. Dietz Prevalence of the metabolic syndrome among US adults: findings from the third National Health and Nutrition Examination Survey JAMA 287 2002 356 359 (Pubitemid 34251969)
-
(2002)
Journal of the American Medical Association
, vol.287
, Issue.3
, pp. 356-359
-
-
Ford, E.S.1
Giles, W.H.2
Dietz, W.H.3
-
2
-
-
68549085226
-
Health care utilization and costs by metabolic syndrome risk factors
-
D.M. Boudreau, D.C. Malone, M.A. Raebel, P.A. Fishman, G.A. Nichols, A.C. Feldstein, A.N. Boscoe, R.H. Ben-Joseph, D.J. Magid, and L.J. Okamoto Health care utilization and costs by metabolic syndrome risk factors Metab. Syndr. Relat. Disord. 7 2009 305 314
-
(2009)
Metab. Syndr. Relat. Disord.
, vol.7
, pp. 305-314
-
-
Boudreau, D.M.1
Malone, D.C.2
Raebel, M.A.3
Fishman, P.A.4
Nichols, G.A.5
Feldstein, A.C.6
Boscoe, A.N.7
Ben-Joseph, R.H.8
Magid, D.J.9
Okamoto, L.J.10
-
3
-
-
0034837376
-
Cardiovascular morbidity and mortality associated with the metabolic syndrome
-
B. Isomaa, P. Almgren, T. Tuomi, B. Forsén, K. Lahti, M. Nissén, M.R. Taskinen, and L. Groop Cardiovascular morbidity and mortality associated with the metabolic syndrome Diabetes Care 24 2001 683 689 (Pubitemid 32893993)
-
(2001)
Diabetes Care
, vol.24
, Issue.4
, pp. 683-689
-
-
Isomaa, B.1
Almgren, P.2
Tuomi, T.3
Forsen, B.4
Lahti, K.5
Nissen, M.6
Taskinen, M.-R.7
Groop, L.8
-
4
-
-
0024160877
-
Role of insulin resistance in human disease
-
G. Reaven Banting Lecture 1988: role of insulin resistance in human disease Diabetes 37 1988 1595 1607 (Pubitemid 19004941)
-
(1988)
Diabetes
, vol.37
, Issue.12
, pp. 1595-1607
-
-
Reaven, G.M.1
-
5
-
-
85030434746
-
Increased oxidative stress in obesity and its impact on metabolic syndrome
-
DOI 10.1172/JCI200421625
-
S. Furukawa, T. Fujita, M. Shimabukuro, M. Iwaki, Y. Yamada, Y. Nakajima, O. Nakayama, M. Makishima, M. Matsuda, and I. Shimomura Increased oxidative stress in obesity and its impact on metabolic syndrome J. Clin. Invest. 114 2004 1752 1761 (Pubitemid 40385531)
-
(2004)
Journal of Clinical Investigation
, vol.114
, Issue.12
, pp. 1752-1761
-
-
Furukawa, S.1
Fujita, T.2
Shimabukuro, M.3
Iwaki, M.4
Yamada, Y.5
Nakajima, Y.6
Nakayama, O.7
Makishima, M.8
Matsuda, M.9
Shimomura, I.10
-
6
-
-
33846450659
-
Nitrosative stress and pathogenesis of insulin resistance
-
DOI 10.1089/ars.2006.1464
-
M. Kaneki, N. Shimizu, D. Yamada, and K. Chang Nitrosative stress and pathogenesis of insulin resistance Antioxid. Redox Signal. 9 2007 319 329 (Pubitemid 46145980)
-
(2007)
Antioxidants and Redox Signaling
, vol.9
, Issue.3
, pp. 319-329
-
-
Kaneki, M.1
Shimizu, N.2
Yamada, D.3
Chang, K.4
-
7
-
-
0038025371
-
Mitochondrial dysfunction in the elderly: Possible role in insulin resistance
-
DOI 10.1126/science.1082889
-
K.F. Petersen, D. Befroy, S. Dufour, J. Dziura, C. Ariyan, D.L. Rothman, L. DiPietro, G.W. Cline, and G.I. Shulman Mitochondrial dysfunction in the elderly: possible role in insulin resistance Science 300 2003 1140 1142 (Pubitemid 36583097)
-
(2003)
Science
, vol.300
, Issue.5622
, pp. 1140-1142
-
-
Petersen, K.F.1
Befroy, D.2
Dufour, S.3
Dziura, J.4
Ariyan, C.5
Rothman, D.L.6
DiPietro, L.7
Cline, G.W.8
Shulman, G.I.9
-
8
-
-
58249085901
-
High fat diet induces dysregulation of hepatic oxygen gradients and mitochondrial function in vivo
-
S.K. Mantena, D.P. Vaughn, K.K. Andringa, H.B. Eccleston, A.L. King, G.A. Abrams, J.E. Doeller, D.W. Kraus, V.M. Darley-Usmar, and S.M. Bailey High fat diet induces dysregulation of hepatic oxygen gradients and mitochondrial function in vivo Biochem. J. 417 2009 183 193
-
(2009)
Biochem. J.
, vol.417
, pp. 183-193
-
-
Mantena, S.K.1
Vaughn, D.P.2
Andringa, K.K.3
Eccleston, H.B.4
King, A.L.5
Abrams, G.A.6
Doeller, J.E.7
Kraus, D.W.8
Darley-Usmar, V.M.9
Bailey, S.M.10
-
9
-
-
0033605261
-
Obesity induces expression of uncoupling protein-2 in hepatocytes and promotes liver ATP depletion
-
DOI 10.1074/jbc.274.9.5692
-
K.D. Chavin, S. Yang, H.Z. Lin, J. Chatham, V.P. Chacko, J.B. Hoek, E. Walajtys-Rode, A. Rashid, C.H. Chen, C.C. Huang, T.C. Wu, M.D. Lane, and A.M. Diehl Obesity induces expression of uncoupling protein-2 in hepatocytes and promotes liver ATP depletion J. Biol. Chem. 274 1999 5692 5700 (Pubitemid 29109222)
-
(1999)
Journal of Biological Chemistry
, vol.274
, Issue.9
, pp. 5692-5700
-
-
Chavin, K.D.1
Yang, S.2
Lin, H.Z.3
Chatham, J.4
Chacko, V.P.5
Hock, J.B.6
Walajtys-Rode, E.7
Rashid, A.8
Chen, C.-H.9
Huang, C.-C.10
Wu, T.-C.11
Lane, M.D.12
Diehl, A.M.13
-
10
-
-
58249093939
-
How mitochondria produce reactive oxygen species
-
M.P. Murphy How mitochondria produce reactive oxygen species Biochem. J. 417 2009 1 13
-
(2009)
Biochem. J.
, vol.417
, pp. 1-13
-
-
Murphy, M.P.1
-
11
-
-
68549112975
-
Mitochondria-targeted antioxidant MitoQ10 improves endothelial function and attenuates cardiac hypertrophy
-
D. Graham, N.N. Huynh, C.A. Hamilton, E. Beattie, R.A. Smith, H.M. Cochemé, M.P. Murphy, and A.F. Dominiczak Mitochondria-targeted antioxidant MitoQ10 improves endothelial function and attenuates cardiac hypertrophy Hypertension 54 2009 322 328
-
(2009)
Hypertension
, vol.54
, pp. 322-328
-
-
Graham, D.1
Huynh, N.N.2
Hamilton, C.A.3
Beattie, E.4
Smith, R.A.5
Cochemé, H.M.6
Murphy, M.P.7
Dominiczak, A.F.8
-
12
-
-
78649755150
-
Prevention of diabetic nephropathy in Ins2(+/)(AkitaJ) mice by the mitochondria-targeted therapy MitoQ
-
B.K. Chacko, C. Reily, A. Srivastava, M.S. Johnson, Y. Ye, E. Ulasova, A. Agarwal, K.R. Zinn, M.P. Murphy, B. Kalyanaraman, and V. Darley-Usmar Prevention of diabetic nephropathy in Ins2(+/)(AkitaJ) mice by the mitochondria-targeted therapy MitoQ Biochem. J. 432 2010 9 19
-
(2010)
Biochem. J.
, vol.432
, pp. 9-19
-
-
Chacko, B.K.1
Reily, C.2
Srivastava, A.3
Johnson, M.S.4
Ye, Y.5
Ulasova, E.6
Agarwal, A.7
Zinn, K.R.8
Murphy, M.P.9
Kalyanaraman, B.10
Darley-Usmar, V.11
-
13
-
-
79959538979
-
Mitochondria-targeted ubiquinone (MitoQ) decreases ethanol-dependent micro and macro hepatosteatosis
-
B.K. Chacko, A. Srivastava, M.S. Johnson, G.A. Benavides, M.J. Chang, Y. Ye, N. Jhala, M.P. Murphy, B. Kalyanaraman, and V.M. Darley-Usmar Mitochondria-targeted ubiquinone (MitoQ) decreases ethanol-dependent micro and macro hepatosteatosis Hepatology 54 2011 153 163
-
(2011)
Hepatology
, vol.54
, pp. 153-163
-
-
Chacko, B.K.1
Srivastava, A.2
Johnson, M.S.3
Benavides, G.A.4
Chang, M.J.5
Ye, Y.6
Jhala, N.7
Murphy, M.P.8
Kalyanaraman, B.9
Darley-Usmar, V.M.10
-
14
-
-
0035895888
-
Selective targeting of a redox-active ubiquinone to mitochondria within cells: Antioxidant and antiapoptotic properties
-
G.F. Kelso, C.M. Porteous, C.V. Coulter, G. Hughes, W.K. Porteous, E.C. Ledgerwood, R.A. Smith, and M.P. Murphy Selective targeting of a redox-active ubiquinone to mitochondria within cells: antioxidant and antiapoptotic properties J. Biol. Chem. 276 2001 4588 4596
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 4588-4596
-
-
Kelso, G.F.1
Porteous, C.M.2
Coulter, C.V.3
Hughes, G.4
Porteous, W.K.5
Ledgerwood, E.C.6
Smith, R.A.7
Murphy, M.P.8
-
15
-
-
77955792985
-
A double-blind, placebo-controlled study to assess the mitochondria-targeted antioxidant MitoQ as a disease-modifying therapy in Parkinson's disease
-
B.J. Snow, F.L. Rolfe, M.M. Lockhart, C.M. Frampton, J.D. O'Sullivan, V. Fung, R.A. Smith, M.P. Murphy, K.M. Taylor, and P.S. Group A double-blind, placebo-controlled study to assess the mitochondria-targeted antioxidant MitoQ as a disease-modifying therapy in Parkinson's disease Mov. Disord. 25 2010 1670 1674
-
(2010)
Mov. Disord.
, vol.25
, pp. 1670-1674
-
-
Snow, B.J.1
Rolfe, F.L.2
Lockhart, M.M.3
Frampton, C.M.4
O'Sullivan, J.D.5
Fung, V.6
Smith, R.A.7
Murphy, M.P.8
Taylor, K.M.9
-
16
-
-
77956496245
-
The mitochondria-targeted anti-oxidant mitoquinone decreases liver damage in a phase II study of hepatitis C patients
-
E.J. Gane, F. Weilert, D.W. Orr, G.F. Keogh, M. Gibson, M.M. Lockhart, C.M. Frampton, K.M. Taylor, R.A. Smith, and M.P. Murphy The mitochondria- targeted anti-oxidant mitoquinone decreases liver damage in a phase II study of hepatitis C patients Liver Int. 30 2010 1019 1026
-
(2010)
Liver Int.
, vol.30
, pp. 1019-1026
-
-
Gane, E.J.1
Weilert, F.2
Orr, D.W.3
Keogh, G.F.4
Gibson, M.5
Lockhart, M.M.6
Frampton, C.M.7
Taylor, K.M.8
Smith, R.A.9
Murphy, M.P.10
-
17
-
-
1842580567
-
Hepatic Steatosis: A Mediator of the Metabolic Syndrome. Lessons from Animal Models
-
DOI 10.1161/01.ATV.0000116217.57583.6e
-
M. den Boer, P.J. Voshol, F. Kuipers, L.M. Havekes, and J.A. Romijn Hepatic steatosis: a mediator of the metabolic syndrome. Lessons from animal models Arterioscler. Thromb. Vasc. Biol. 24 2004 644 649 (Pubitemid 38451598)
-
(2004)
Arteriosclerosis, Thrombosis, and Vascular Biology
, vol.24
, Issue.4
, pp. 644-649
-
-
Den Boer, M.1
Voshol, P.J.2
Kuipers, F.3
Havekes, L.M.4
Romijn, J.A.5
-
18
-
-
79955096123
-
Hepatocyte-specific hypoxia-inducible factor-1α is a determinant of lipid accumulation and liver injury in alcohol-induced steatosis in mice
-
B. Nath, I. Levin, T. Csak, J. Petrasek, C. Mueller, K. Kodys, D. Catalano, P. Mandrekar, and G. Szabo Hepatocyte-specific hypoxia-inducible factor-1α is a determinant of lipid accumulation and liver injury in alcohol-induced steatosis in mice Hepatology 53 2011 1526 1537
-
(2011)
Hepatology
, vol.53
, pp. 1526-1537
-
-
Nath, B.1
Levin, I.2
Csak, T.3
Petrasek, J.4
Mueller, C.5
Kodys, K.6
Catalano, D.7
Mandrekar, P.8
Szabo, G.9
-
19
-
-
84934442193
-
Mitochondrial reactive oxygen species are required for hypoxic HIF alpha stabilization
-
M.C. Simon Mitochondrial reactive oxygen species are required for hypoxic HIF alpha stabilization Adv. Exp. Med. Biol. 588 2006 165 170
-
(2006)
Adv. Exp. Med. Biol.
, vol.588
, pp. 165-170
-
-
Simon, M.C.1
-
20
-
-
33644629183
-
Coming up for air: HIF-1 and mitochondrial oxygen consumption
-
M.C. Simon Coming up for air: HIF-1 and mitochondrial oxygen consumption Cell Metab. 3 2006 150 151
-
(2006)
Cell Metab.
, vol.3
, pp. 150-151
-
-
Simon, M.C.1
-
21
-
-
36349024676
-
Atherosclerosis is attenuated by limiting superoxide generation in both macrophages and vessel wall cells
-
DOI 10.1161/ATVBAHA.107.152629
-
A.E. Vendrov, Z.S. Hakim, N.R. Madamanchi, M. Rojas, C. Madamanchi, and M.S. Runge Atherosclerosis is attenuated by limiting superoxide generation in both macrophages and vessel wall cells Arterioscler. Thromb. Vasc. Biol. 27 2007 2714 2721 (Pubitemid 350158927)
-
(2007)
Arteriosclerosis, Thrombosis, and Vascular Biology
, vol.27
, Issue.12
, pp. 2714-2721
-
-
Vendrov, A.E.1
Hakim, Z.S.2
Madamanchi, N.R.3
Rojas, M.4
Madamanchi, C.5
Runge, M.S.6
-
22
-
-
33750475625
-
Free radicals, mitochondria, and oxidized lipids: The emerging role in signal transduction in vascular cells
-
DOI 10.1161/01.RES.0000248212.86638.e9, PII 0000301220061027000005
-
J. Gutierrez, S.W. Ballinger, V.M. Darley-Usmar, and A. Landar Free radicals, mitochondria, and oxidized lipids: the emerging role in signal transduction in vascular cells Circ. Res. 99 2006 924 932 (Pubitemid 44657795)
-
(2006)
Circulation Research
, vol.99
, Issue.9
, pp. 924-932
-
-
Gutierrez, J.1
Ballinger, S.W.2
Darley-Usmar, V.M.3
Landar, A.4
-
23
-
-
79951982900
-
The mitochondria-targeted antioxidant mitoquinone protects against cold storage injury of renal tubular cells and rat kidneys
-
T. Mitchell, D. Rotaru, H. Saba, R.A. Smith, M.P. Murphy, and L.A. MacMillan-Crow The mitochondria-targeted antioxidant mitoquinone protects against cold storage injury of renal tubular cells and rat kidneys J. Pharmacol. Exp. Ther. 336 2011 682 692
-
(2011)
J. Pharmacol. Exp. Ther.
, vol.336
, pp. 682-692
-
-
Mitchell, T.1
Rotaru, D.2
Saba, H.3
Smith, R.A.4
Murphy, M.P.5
MacMillan-Crow, L.A.6
-
24
-
-
33645765312
-
Diabetes and mitochondrial function: Role of hyperglycemia and oxidative stress
-
A.P. Rolo, and C.M. Palmeira Diabetes and mitochondrial function: role of hyperglycemia and oxidative stress Toxicol. Appl. Pharmacol. 212 2006 167 178
-
(2006)
Toxicol. Appl. Pharmacol.
, vol.212
, pp. 167-178
-
-
Rolo, A.P.1
Palmeira, C.M.2
-
25
-
-
84856752588
-
-/- mice
-
-/- mice Free Radic. Biol. Med. 52 2012 841 849
-
(2012)
Free Radic. Biol. Med.
, vol.52
, pp. 841-849
-
-
Mercer, J.R.1
Yu, E.2
Figg, N.3
Cheng, K.K.4
Prime, T.A.5
Griffin, J.L.6
Masoodi, M.7
Vidal-Puig, A.8
Murphy, M.P.9
Bennett, M.R.10
|