Structural characterization of viral ortholog of human DNA glycosylase NEIL1 bound to thymine glycol or 5-hydroxyuracil-containing DNA

Journal of Biological Chemistry

Volumn 287, Issue 6, 2012, Pages 4288-4298

  Imamura, Kayo ^a   Averill, April ^a   Wallace, Susan S ^a   Doublié, Sylvie ^a  

^a UNIVERSITY OF VERMONT COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVE SITE; ANTI-CONFORMATIONS; APYRIMIDINIC; BASE EXCISION REPAIRS; DNA GLYCOSYLASE; DNA LESIONS; ENDONUCLEASES; GLYCOSYLASE; HYDROGEN BONDINGS; ORTHOLOGS; OXIDIZED PRODUCTS; SIDE-CHAINS; STRUCTURAL CHARACTERIZATION;

AROMATIC COMPOUNDS; CONFORMATIONS; GLYCOLS;

DNA;

5 HDYROXYURACIL; DNA GLYCOSYLTRANSFERASE; DNA GLYCOSYLTRANSFERASE NEIL1; GLUTAMIC ACID; HYDROGEN; THYMINE DNA GLYCOSYLASE; TYROSINE; UNCLASSIFIED DRUG; URACIL DERIVATIVE;

APURINIC SITE; ARTICLE; CONTROLLED STUDY; CRYSTAL STRUCTURE; DNA BINDING; DNA CONFORMATION; DNA DAMAGE; DNA HELIX; DNA STRUCTURE; ENZYME ACTIVE SITE; ENZYME ACTIVITY; HYDROGEN BOND; MIMIVIRUS; MOLECULAR RECOGNITION; ORTHOLOGY; OXIDATION; PRIORITY JOURNAL; X RAY CRYSTALLOGRAPHY;

CATALYTIC DOMAIN; CRYSTALLOGRAPHY, X-RAY; DNA; DNA GLYCOSYLASES; HUMANS; MIMIVIRIDAE; OXIDATION-REDUCTION; THYMINE; URACIL;

MIMIVIRUS;

EID: 84856695671     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.315309     Document Type: Article

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