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Volumn 41, Issue 5, 2011, Pages 1249-1255

Sub-optimal CD4+ T-cell activation triggers autonomous TGF-β-dependent conversion to Foxp3+ regulatory T cells

Author keywords

Anti CD4; Foxp3; TGF b; Transplantation tolerance; Treg

Indexed keywords

CD4 ANTIBODY; IMMUNOGLOBULIN; INTERLEUKIN 2; T LYMPHOCYTE RECEPTOR; TRANSCRIPTION FACTOR FOXP3; TRANSFORMING GROWTH FACTOR BETA;

EID: 79952915024     PISSN: 00142980     EISSN: 15214141     Source Type: Journal    
DOI: 10.1002/eji.201040896     Document Type: Article
Times cited : (41)

References (24)
  • 1
    • 43949105866 scopus 로고    scopus 로고
    • Regulatory T cells and immune tolerance
    • Sakaguchi, S., Yamaguchi, T., Nomura, T. and Ono, M., Regulatory T cells and immune tolerance. Cell 2008. 133: 775-787.
    • (2008) Cell , vol.133 , pp. 775-787
    • Sakaguchi, S.1    Yamaguchi, T.2    Nomura, T.3    Ono, M.4
  • 2
    • 33746342994 scopus 로고    scopus 로고
    • Foxp3+ CD25+ CD4+ natural regulatory T cells in dominant self-tolerance and autoimmune disease
    • Sakaguchi, S., Ono, M., Setoguchi, R., Yagi, H., Hori, S., Fehervari, Z., Shimizu, J. et al., Foxp3+ CD25+ CD4+ natural regulatory T cells in dominant self-tolerance and autoimmune disease. Immunol. Rev. 2006. 212: 8-27.
    • (2006) Immunol. Rev. , vol.212 , pp. 8-27
    • Sakaguchi, S.1    Ono, M.2    Setoguchi, R.3    Yagi, H.4    Hori, S.5    Fehervari, Z.6    Shimizu, J.7
  • 3
    • 17144374934 scopus 로고    scopus 로고
    • Regulatory T-cell therapy: is it ready for the clinic?
    • Bluestone, J. A., Regulatory T-cell therapy: is it ready for the clinic? Nat. Rev. Immunol. 2005. 5: 343-349.
    • (2005) Nat. Rev. Immunol. , vol.5 , pp. 343-349
    • Bluestone, J.A.1
  • 4
    • 0037783493 scopus 로고    scopus 로고
    • Regulatory T cells in the induction and maintenance of peripheral transplantation tolerance
    • Cobbold, S. P., Graca, L., Lin, C. Y., Adams, E. and Waldmann, H., Regulatory T cells in the induction and maintenance of peripheral transplantation tolerance. Transpl. Int. 2003. 16: 66-75.
    • (2003) Transpl. Int. , vol.16 , pp. 66-75
    • Cobbold, S.P.1    Graca, L.2    Lin, C.Y.3    Adams, E.4    Waldmann, H.5
  • 5
    • 34547204632 scopus 로고    scopus 로고
    • Adaptive TGF-beta-dependent regulatory T cells control autoimmune diabetes and are a privileged target of anti-CD3 antibody treatment
    • You, S., Leforban, B., Garcia, C., Bach, J. F., Bluestone, J. A. and Chatenoud, L., Adaptive TGF-beta-dependent regulatory T cells control autoimmune diabetes and are a privileged target of anti-CD3 antibody treatment. Proc. Natl. Acad. Sci. USA 2007. 104: 6335-6340.
    • (2007) Proc. Natl. Acad. Sci. USA , vol.104 , pp. 6335-6340
    • You, S.1    Leforban, B.2    Garcia, C.3    Bach, J.F.4    Bluestone, J.A.5    Chatenoud, L.6
  • 6
    • 1642454708 scopus 로고    scopus 로고
    • Alloantigen-induced CD25+CD4+ regulatory T cells can develop in vivo from CD25-CD4+ precursors in a thymus-independent process
    • Karim, M., Kingsley, C. I., Bushell, A. R., Sawitzki, B. S. and Wood, K. J., Alloantigen-induced CD25+CD4+ regulatory T cells can develop in vivo from CD25-CD4+ precursors in a thymus-independent process. J. Immunol. 2004. 172: 923-928.
    • (2004) J. Immunol. , vol.172 , pp. 923-928
    • Karim, M.1    Kingsley, C.I.2    Bushell, A.R.3    Sawitzki, B.S.4    Wood, K.J.5
  • 7
    • 44649144463 scopus 로고    scopus 로고
    • Autoantigen-specific TGFbeta-induced Foxp3+ regulatory T cells prevent autoimmunity by inhibiting dendritic cells from activating autoreactive T cells
    • DiPaolo, R. J., Brinster, C., Davidson, T. S., Andersson, J., Glass, D. and Shevach, E. M., Autoantigen-specific TGFbeta-induced Foxp3+ regulatory T cells prevent autoimmunity by inhibiting dendritic cells from activating autoreactive T cells. J. Immunol. 2007. 179: 4685-4693.
    • (2007) J. Immunol. , vol.179 , pp. 4685-4693
    • DiPaolo, R.J.1    Brinster, C.2    Davidson, T.S.3    Andersson, J.4    Glass, D.5    Shevach, E.M.6
  • 8
    • 46749126890 scopus 로고    scopus 로고
    • Adaptive Foxp3+ regulatory T cell-dependent and -independent control of allergic inflammation
    • Curotto de Lafaille, M. A., Kutchukhidze, N., Shen, S., Ding, Y., Yee, H. and Lafaille, J. J., Adaptive Foxp3+ regulatory T cell-dependent and -independent control of allergic inflammation. Immunity 2008. 29: 114-126.
    • (2008) Immunity , vol.29 , pp. 114-126
    • Curotto de Lafaille, M.A.1    Kutchukhidze, N.2    Shen, S.3    Ding, Y.4    Yee, H.5    Lafaille, J.J.6
  • 9
    • 2442425262 scopus 로고    scopus 로고
    • Induction of foxP3+ regulatory T cells in the periphery of T cell receptor transgenic mice tolerized to transplants
    • Cobbold, S. P., Castejon, R., Adams, E., Zelenika, D., Graca, L., Humm, S. and Waldmann, H., Induction of foxP3+ regulatory T cells in the periphery of T cell receptor transgenic mice tolerized to transplants. J. Immunol. 2004. 172: 6003-6010.
    • (2004) J. Immunol. , vol.172 , pp. 6003-6010
    • Cobbold, S.P.1    Castejon, R.2    Adams, E.3    Zelenika, D.4    Graca, L.5    Humm, S.6    Waldmann, H.7
  • 11
    • 58149286586 scopus 로고    scopus 로고
    • Intrinsic and induced regulation of the age-associated onset of spontaneous experimental autoimmune encephalomyelitis
    • Zhang, H., Podojil, J. R., Luo, X. and Miller, S. D., Intrinsic and induced regulation of the age-associated onset of spontaneous experimental autoimmune encephalomyelitis. J. Immunol. 2008. 181: 4638-4647.
    • (2008) J. Immunol. , vol.181 , pp. 4638-4647
    • Zhang, H.1    Podojil, J.R.2    Luo, X.3    Miller, S.D.4
  • 12
    • 0348223787 scopus 로고    scopus 로고
    • Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory T cells by TGF-beta induction of transcription factor Foxp3
    • Chen, W., Jin, W., Hardegen, N., Lei, K. J., Li, L., Marinos, N., McGrady, G. and Wahl, S. M., Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory T cells by TGF-beta induction of transcription factor Foxp3. J. Exp. Med. 2003. 198: 1875-1886.
    • (2003) J. Exp. Med. , vol.198 , pp. 1875-1886
    • Chen, W.1    Jin, W.2    Hardegen, N.3    Lei, K.J.4    Li, L.5    Marinos, N.6    McGrady, G.7    Wahl, S.M.8
  • 13
    • 49849094011 scopus 로고    scopus 로고
    • Natural and TGF-beta-induced Foxp3(+)CD4(+) CD25(+) regulatory T cells are not mirror images of each other
    • Horwitz, D. A., Zheng, S. G. and Gray, J. D., Natural and TGF-beta-induced Foxp3(+)CD4(+) CD25(+) regulatory T cells are not mirror images of each other. Trends Immunol. 2008. 29: 429-435.
    • (2008) Trends Immunol. , vol.29 , pp. 429-435
    • Horwitz, D.A.1    Zheng, S.G.2    Gray, J.D.3
  • 15
    • 65349188127 scopus 로고    scopus 로고
    • Translating costimulation blockade to the clinic: lessons learned from three pathways
    • Ford, M. L. and Larsen, C. P., Translating costimulation blockade to the clinic: lessons learned from three pathways. Immunol. Rev. 2009. 229: 294-306.
    • (2009) Immunol. Rev. , vol.229 , pp. 294-306
    • Ford, M.L.1    Larsen, C.P.2
  • 16
    • 2342652841 scopus 로고    scopus 로고
    • Transplantation tolerance induced by intranasal administration of HY peptides
    • Chai, J. G., James, E., Dewchand, H., Simpson, E. and Scott, D., Transplantation tolerance induced by intranasal administration of HY peptides. Blood 2004. 103: 3951-3959.
    • (2004) Blood , vol.103 , pp. 3951-3959
    • Chai, J.G.1    James, E.2    Dewchand, H.3    Simpson, E.4    Scott, D.5
  • 17
    • 0036715411 scopus 로고    scopus 로고
    • Immature, semi-mature and fully mature dendritic cells: which signals induce tolerance or immunity?
    • Lutz, M. B. and Schuler, G., Immature, semi-mature and fully mature dendritic cells: which signals induce tolerance or immunity? Trends Immunol. 2002. 23: 445-449.
    • (2002) Trends Immunol. , vol.23 , pp. 445-449
    • Lutz, M.B.1    Schuler, G.2
  • 19
    • 14644388075 scopus 로고    scopus 로고
    • Dominant tolerance: activation thresholds for peripheral generation of regulatory T cells
    • Graca, L., Chen, T. C., Le Moine, A., Cobbold, S. P., Howie, D. and Waldmann, H., Dominant tolerance: activation thresholds for peripheral generation of regulatory T cells. Trends Immunol. 2005. 26: 130-135.
    • (2005) Trends Immunol. , vol.26 , pp. 130-135
    • Graca, L.1    Chen, T.C.2    Le Moine, A.3    Cobbold, S.P.4    Howie, D.5    Waldmann, H.6
  • 20
    • 34547757390 scopus 로고    scopus 로고
    • Small intestine lamina propria dendritic cells promote de novo generation of Foxp3 T reg cells via retinoic acid
    • Sun, C. M., Hall, J. A., Blank, R. B., Bouladoux, N., Oukka, M., Mora, J. R. and Belkaid, Y., Small intestine lamina propria dendritic cells promote de novo generation of Foxp3 T reg cells via retinoic acid. J. Exp. Med. 2007. 204: 1775-1785.
    • (2007) J. Exp. Med. , vol.204 , pp. 1775-1785
    • Sun, C.M.1    Hall, J.A.2    Blank, R.B.3    Bouladoux, N.4    Oukka, M.5    Mora, J.R.6    Belkaid, Y.7
  • 22
    • 0035162560 scopus 로고    scopus 로고
    • Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse
    • Brunkow, M. E., Jeffery, E. W., Hjerrild, K. A., Paeper, B., Clark, L. B., Yasayko, S. A., Wilkinson, J. E. et al., Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse. Nat. Genet. 2001. 27: 68-73.
    • (2001) Nat. Genet. , vol.27 , pp. 68-73
    • Brunkow, M.E.1    Jeffery, E.W.2    Hjerrild, K.A.3    Paeper, B.4    Clark, L.B.5    Yasayko, S.A.6    Wilkinson, J.E.7
  • 23
    • 77955391804 scopus 로고    scopus 로고
    • TCR ligand density and affinity determine peripheral induction of Foxp3 in vivo
    • Gottschalk, R. A., Corse, E. and Allison, J. P., TCR ligand density and affinity determine peripheral induction of Foxp3 in vivo. J. Exp. Med. 2010. 207: 1701-1711.
    • (2010) J. Exp. Med. , vol.207 , pp. 1701-1711
    • Gottschalk, R.A.1    Corse, E.2    Allison, J.P.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.