A novel small Odorranalectin-bearing cubosomes: Preparation, brain delivery and pharmacodynamic study on amyloid-β 25-35-treated rats following intranasal administration

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 80, Issue 2, 2012, Pages 368-378

  Wu, Hongbing ^a,c   Li, Jianxu ^b   Zhang, Qizhi ^a   Yan, Xiluan ^a   Guo, Liangran ^a   Gao, Xiaoling ^d   Qiu, Mingfeng ^c   Jiang, Xinguo ^a   Lai, Ren ^b   Chen, Hongzhuan ^d  

^a FUDAN UNIVERSITY   (China)

^b KUNMING INSTITUTE OF ZOOLOGY   (China)

^c SHANGHAI JIAO TONG UNIVERSITY   (China)

^d SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

Alzheimer's disease; Brain delivery; Cubosomes; Gly14 Humanin; Intranasal administration; Odorranalectin

Indexed keywords

ACETYLCHOLINESTERASE; AMYLOID BETA PROTEIN[25-35]; BIOTIN; COUMARIN; CUBOSOME; HUMANIN; LECTIN; LIGAND; MACROGOL; MALEIMIDE; NANOPARTICLE; ODORRANALECTIN; STREPTAVIDIN; THIOL GROUP; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; BINDING AFFINITY; BIOTINYLATION; BRAIN TISSUE; CHEMOLUMINESCENCE; CONFERENCE PAPER; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; ENZYME ACTIVITY; HEMAGGLUTINATION; IMMUNOGENICITY; IN VIVO STUDY; MAZE TEST; NEUROPROTECTION; NONHUMAN; NOSE; RAT;

ADMINISTRATION, INTRANASAL; ALZHEIMER DISEASE; AMYLOID BETA-PEPTIDES; ANIMALS; BRAIN; COUMARINS; DISEASE MODELS, ANIMAL; DRUG CARRIERS; DRUG DELIVERY SYSTEMS; GLYCINE; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LECTINS; MAZE LEARNING; PEPTIDE FRAGMENTS; RATS; RATS, SPRAGUE-DAWLEY; STREPTAVIDIN; THIAZOLES; TISSUE DISTRIBUTION;

EID: 84856607696     PISSN: 09396411     EISSN: 18733441     Source Type: Journal    
DOI: 10.1016/j.ejpb.2011.10.012     Document Type: Conference Paper

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