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Volumn 30, Issue 7, 2012, Pages 1364-1370

Epitope based recombinant BCG vaccine elicits specific Th1 polarized immune responses in BALB/c mice

Author keywords

Epitope; Heat shock protein; Mycobacterium tuberculosis; Recombinant BCG; Vaccine

Indexed keywords

BACTERIAL PROTEIN; BACTERIAL VACCINE; BCG VACCINE; CULTURE FILTRATE PROTEIN 10; EPITOPE; FBP PROTEIN; GAMMA INTERFERON; IMMUNOGLOBULIN G1; IMMUNOGLOBULIN G2A; INTERLEUKIN 4; INV PROTEIN; MYCOBACTERIUM ANTIGEN; PPE68 PROTEIN; RECOMBINANT BCG VACCINE; RECOMBINANT VACCINE; T LYMPHOCYTE ANTIGEN; UNCLASSIFIED DRUG;

EID: 84856569744     PISSN: 0264410X     EISSN: 18732518     Source Type: Journal    
DOI: 10.1016/j.vaccine.2011.12.059     Document Type: Article
Times cited : (23)

References (38)
  • 1
    • 33748047496 scopus 로고    scopus 로고
    • Envisioning future strategies for vaccination against tuberculosis
    • September
    • Kaufmann S.H. Envisioning future strategies for vaccination against tuberculosis. Nat Rev Immunol 2006, 6(September (9)):699-704.
    • (2006) Nat Rev Immunol , vol.6 , Issue.9 , pp. 699-704
    • Kaufmann, S.H.1
  • 2
    • 66549117134 scopus 로고    scopus 로고
    • The quest for a new vaccine against tuberculosis
    • Delogu G., Fadda G. The quest for a new vaccine against tuberculosis. J Infect Dev Ctries 2009, 3(1):5-15.
    • (2009) J Infect Dev Ctries , vol.3 , Issue.1 , pp. 5-15
    • Delogu, G.1    Fadda, G.2
  • 3
    • 79957584452 scopus 로고    scopus 로고
    • Tuberculosis vaccines in clinical trials
    • May
    • Rowland R., McShane H. Tuberculosis vaccines in clinical trials. Expert Rev Vaccines 2011, 10(May (5)):645-658.
    • (2011) Expert Rev Vaccines , vol.10 , Issue.5 , pp. 645-658
    • Rowland, R.1    McShane, H.2
  • 4
    • 0035495579 scopus 로고    scopus 로고
    • How can immunology contribute to the control of tuberculosis?
    • October
    • Kaufmann S.H. How can immunology contribute to the control of tuberculosis?. Nat Rev Immunol 2001, 1(October (1)):20-30.
    • (2001) Nat Rev Immunol , vol.1 , Issue.1 , pp. 20-30
    • Kaufmann, S.H.1
  • 5
    • 46749121412 scopus 로고    scopus 로고
    • Tuberculosis vaccine development: goals, immunological design, and evaluation
    • July
    • Hoft D.F. Tuberculosis vaccine development: goals, immunological design, and evaluation. Lancet 2008, 372(July (9633)):164-175.
    • (2008) Lancet , vol.372 , Issue.9633 , pp. 164-175
    • Hoft, D.F.1
  • 6
    • 68349101256 scopus 로고    scopus 로고
    • A novel DNA vaccine containing multiple TB-specific epitopes casted in a natural structure (ECANS) confers protective immunity against pulmonary mycobacterial challenge
    • August
    • Gao H., Yue Y., Hu L., Xu W., Xiong S. A novel DNA vaccine containing multiple TB-specific epitopes casted in a natural structure (ECANS) confers protective immunity against pulmonary mycobacterial challenge. Vaccine 2009, 27(August (39)):5313-5319.
    • (2009) Vaccine , vol.27 , Issue.39 , pp. 5313-5319
    • Gao, H.1    Yue, Y.2    Hu, L.3    Xu, W.4    Xiong, S.5
  • 7
    • 77952762373 scopus 로고    scopus 로고
    • CD4+ T cell epitope discovery and rational vaccine design
    • April
    • Rosa D.S., Ribeiro S.P., Cunha-Neto E. CD4+ T cell epitope discovery and rational vaccine design. Arch Immunol Ther Exp (Warsz) 2010, 58(April (2)):121-130.
    • (2010) Arch Immunol Ther Exp (Warsz) , vol.58 , Issue.2 , pp. 121-130
    • Rosa, D.S.1    Ribeiro, S.P.2    Cunha-Neto, E.3
  • 8
    • 0041402836 scopus 로고    scopus 로고
    • Epitope-based vaccines: an update on epitope identification, vaccine design and delivery
    • August
    • Sette A., Fikes J. Epitope-based vaccines: an update on epitope identification, vaccine design and delivery. Curr Opin Immunol 2003, 15(August (4)):461-470.
    • (2003) Curr Opin Immunol , vol.15 , Issue.4 , pp. 461-470
    • Sette, A.1    Fikes, J.2
  • 10
    • 18544370572 scopus 로고    scopus 로고
    • Optimizing vaccine design for cellular processing, MHC binding and TCR recognition
    • June
    • Sette A., Newman M., Livingston B., McKinney D., Sidney J., Ishioka G., et al. Optimizing vaccine design for cellular processing, MHC binding and TCR recognition. Tissue Antigens 2002, 59(June (6)):443-451.
    • (2002) Tissue Antigens , vol.59 , Issue.6 , pp. 443-451
    • Sette, A.1    Newman, M.2    Livingston, B.3    McKinney, D.4    Sidney, J.5    Ishioka, G.6
  • 12
    • 12344281084 scopus 로고    scopus 로고
    • Factors influencing the immune response to foreign antigen expressed in recombinant BCG vaccines
    • January
    • Dennehy M., Williamson A.L. Factors influencing the immune response to foreign antigen expressed in recombinant BCG vaccines. Vaccine 2005, 23(January (10)):1209-1224.
    • (2005) Vaccine , vol.23 , Issue.10 , pp. 1209-1224
    • Dennehy, M.1    Williamson, A.L.2
  • 13
    • 70350569309 scopus 로고    scopus 로고
    • Recombinant Mycobacterium bovis BCG
    • November
    • Bastos R.G., Borsuk S., Seixas F.K., Dellagostin O.A. Recombinant Mycobacterium bovis BCG. Vaccine 2009, 27(November (47)):6495-6503.
    • (2009) Vaccine , vol.27 , Issue.47 , pp. 6495-6503
    • Bastos, R.G.1    Borsuk, S.2    Seixas, F.K.3    Dellagostin, O.A.4
  • 14
    • 33646718148 scopus 로고    scopus 로고
    • T-h-2 immunity and CD3+CD45RBlow-activated T cells in mice immunized with recombinant bacillus Calmette-Guerin expressing HIV-1 principal neutralizing determinant epitope
    • June
    • Aravindhan V., Narayanan S., Gautham N., Prasad V., Kannan P., Jacobs W.R., et al. T-h-2 immunity and CD3+CD45RBlow-activated T cells in mice immunized with recombinant bacillus Calmette-Guerin expressing HIV-1 principal neutralizing determinant epitope. FEMS Immunol Med Microbiol 2006, 47(June (1)):45-55.
    • (2006) FEMS Immunol Med Microbiol , vol.47 , Issue.1 , pp. 45-55
    • Aravindhan, V.1    Narayanan, S.2    Gautham, N.3    Prasad, V.4    Kannan, P.5    Jacobs, W.R.6
  • 15
    • 0025610701 scopus 로고
    • Establishment of a foreign antigen secretion system in mycobacteria
    • December
    • Matsuo K., Yamaguchi R., Yamazaki A., Tasaka H., Terasaka K., Totsuka M., et al. Establishment of a foreign antigen secretion system in mycobacteria. Infect Immun 1990, 58(December (12)):4049-4054.
    • (1990) Infect Immun , vol.58 , Issue.12 , pp. 4049-4054
    • Matsuo, K.1    Yamaguchi, R.2    Yamazaki, A.3    Tasaka, H.4    Terasaka, K.5    Totsuka, M.6
  • 16
    • 0035852333 scopus 로고    scopus 로고
    • Expression of the B-cell and T-cell epitopes of the rabies virus nucleoprotein in Mycobacterium bovis BCG and induction of an humoral response in mice
    • December
    • Da Cruz F.W., McBride A.J., Conceicao F.R., Dale J.W., McFadden J., Dellagostin O.A. Expression of the B-cell and T-cell epitopes of the rabies virus nucleoprotein in Mycobacterium bovis BCG and induction of an humoral response in mice. Vaccine 2001, 20(December (5-6)):731-736.
    • (2001) Vaccine , vol.20 , Issue.5-6 , pp. 731-736
    • Da Cruz, F.W.1    McBride, A.J.2    Conceicao, F.R.3    Dale, J.W.4    McFadden, J.5    Dellagostin, O.A.6
  • 17
    • 1842588596 scopus 로고    scopus 로고
    • Cell envelope protein PPE68 contributes to Mycobacterium tuberculosis RD1 immunogenicity independently of a 10-kilodalton culture filtrate protein and ESAT-6
    • April
    • Demangel C., Brodin P., Cockle P.J., Brosch R., Majlessi L., Leclerc C., et al. Cell envelope protein PPE68 contributes to Mycobacterium tuberculosis RD1 immunogenicity independently of a 10-kilodalton culture filtrate protein and ESAT-6. Infect Immun 2004, 72(April (4)):2170-2176.
    • (2004) Infect Immun , vol.72 , Issue.4 , pp. 2170-2176
    • Demangel, C.1    Brodin, P.2    Cockle, P.J.3    Brosch, R.4    Majlessi, L.5    Leclerc, C.6
  • 19
    • 0026527762 scopus 로고
    • A major T cell antigen of Mycobacterium leprae is a 10-kD heat-shock cognate protein
    • January
    • Mehra V., Bloom B.R., Bajardi A.C., Grisso C.L., Sieling P.A., Alland D., et al. A major T cell antigen of Mycobacterium leprae is a 10-kD heat-shock cognate protein. J Exp Med 1992, 175(January (1)):275-284.
    • (1992) J Exp Med , vol.175 , Issue.1 , pp. 275-284
    • Mehra, V.1    Bloom, B.R.2    Bajardi, A.C.3    Grisso, C.L.4    Sieling, P.A.5    Alland, D.6
  • 20
    • 0026534109 scopus 로고
    • Immunoreactivity of a 10-kDa antigen of Mycobacterium tuberculosis
    • March
    • Barnes P.F., Mehra V., Rivoire B., Fong S.J., Brennan P.J., Voegtline M.S., et al. Immunoreactivity of a 10-kDa antigen of Mycobacterium tuberculosis. J Immunol 1992, 148(March (6)):1835-1840.
    • (1992) J Immunol , vol.148 , Issue.6 , pp. 1835-1840
    • Barnes, P.F.1    Mehra, V.2    Rivoire, B.3    Fong, S.J.4    Brennan, P.J.5    Voegtline, M.S.6
  • 21
    • 0036008510 scopus 로고    scopus 로고
    • Structure of Mycobacterium tuberculosis chaperonin-10 at 3.5A resolution
    • February
    • Taneja B., Mande S.C. Structure of Mycobacterium tuberculosis chaperonin-10 at 3.5A resolution. Acta Crystallogr D Biol Crystallogr 2002, 58(February (Pt 2)):260-266.
    • (2002) Acta Crystallogr D Biol Crystallogr , vol.58 , Issue.PART 2 , pp. 260-266
    • Taneja, B.1    Mande, S.C.2
  • 22
    • 0036437048 scopus 로고    scopus 로고
    • Loss of RD1 contributed to the attenuation of the live tuberculosis vaccines Mycobacterium bovis BCG and Mycobacterium microti
    • November
    • Pym A.S., Brodin P., Brosch R., Huerre M., Cole S.T. Loss of RD1 contributed to the attenuation of the live tuberculosis vaccines Mycobacterium bovis BCG and Mycobacterium microti. Mol Microbiol 2002, 46(November (3)):709-717.
    • (2002) Mol Microbiol , vol.46 , Issue.3 , pp. 709-717
    • Pym, A.S.1    Brodin, P.2    Brosch, R.3    Huerre, M.4    Cole, S.T.5
  • 23
    • 0037219942 scopus 로고    scopus 로고
    • Deletion of RD1 from Mycobacterium tuberculosis mimics bacille Calmette-Guerin attenuation
    • January
    • Lewis K.N., Liao R., Guinn K.M., Hickey M.J., Smith S., Behr M.A., et al. Deletion of RD1 from Mycobacterium tuberculosis mimics bacille Calmette-Guerin attenuation. J Infect Dis 2003, 187(January (1)):117-123.
    • (2003) J Infect Dis , vol.187 , Issue.1 , pp. 117-123
    • Lewis, K.N.1    Liao, R.2    Guinn, K.M.3    Hickey, M.J.4    Smith, S.5    Behr, M.A.6
  • 24
    • 0038751936 scopus 로고    scopus 로고
    • Recombinant BCG exporting ESAT-6 confers enhanced protection against tuberculosis
    • May
    • Pym A.S., Brodin P., Majlessi L., Brosch R., Demangel C., Williams A., et al. Recombinant BCG exporting ESAT-6 confers enhanced protection against tuberculosis. Nat Med 2003, 9(May (5)):533-539.
    • (2003) Nat Med , vol.9 , Issue.5 , pp. 533-539
    • Pym, A.S.1    Brodin, P.2    Majlessi, L.3    Brosch, R.4    Demangel, C.5    Williams, A.6
  • 25
    • 0034115693 scopus 로고    scopus 로고
    • Antigenic equivalence of human T-cell responses to Mycobacterium tuberculosis-specific RD1-encoded protein antigens ESAT-6 and culture filtrate protein 10 and to mixtures of synthetic peptides
    • June
    • Arend S.M., Geluk A., van Meijgaarden K.E., van Dissel J.T., Theisen M., Andersen P., et al. Antigenic equivalence of human T-cell responses to Mycobacterium tuberculosis-specific RD1-encoded protein antigens ESAT-6 and culture filtrate protein 10 and to mixtures of synthetic peptides. Infect Immun 2000, 68(June (6)):3314-3321.
    • (2000) Infect Immun , vol.68 , Issue.6 , pp. 3314-3321
    • Arend, S.M.1    Geluk, A.2    van Meijgaarden, K.E.3    van Dissel, J.T.4    Theisen, M.5    Andersen, P.6
  • 26
    • 0035253283 scopus 로고    scopus 로고
    • Enumeration of T cells specific for RD1-encoded antigens suggests a high prevalence of latent Mycobacterium tuberculosis infection in healthy urban Indians
    • February
    • Lalvani A., Nagvenkar P., Udwadia Z., Pathan A.A., Wilkinson K.A., Shastri J.S., et al. Enumeration of T cells specific for RD1-encoded antigens suggests a high prevalence of latent Mycobacterium tuberculosis infection in healthy urban Indians. J Infect Dis 2001, 183(February (3)):469-477.
    • (2001) J Infect Dis , vol.183 , Issue.3 , pp. 469-477
    • Lalvani, A.1    Nagvenkar, P.2    Udwadia, Z.3    Pathan, A.A.4    Wilkinson, K.A.5    Shastri, J.S.6
  • 27
    • 0031007903 scopus 로고    scopus 로고
    • Role of the major antigen of Mycobacterium tuberculosis in cell wall biogenesis
    • May
    • Belisle J.T., Vissa V.D., Sievert T., Takayama K., Brennan P.J., Besra G.S. Role of the major antigen of Mycobacterium tuberculosis in cell wall biogenesis. Science 1997, 276(May (5317)):1420-1422.
    • (1997) Science , vol.276 , Issue.5317 , pp. 1420-1422
    • Belisle, J.T.1    Vissa, V.D.2    Sievert, T.3    Takayama, K.4    Brennan, P.J.5    Besra, G.S.6
  • 28
    • 0026465216 scopus 로고
    • The antigen 85 complex: a major secretion product of Mycobacterium tuberculosis
    • December
    • Wiker H.G., Harboe M. The antigen 85 complex: a major secretion product of Mycobacterium tuberculosis. Microbiol Rev 1992, 56(December (4)):648-661.
    • (1992) Microbiol Rev , vol.56 , Issue.4 , pp. 648-661
    • Wiker, H.G.1    Harboe, M.2
  • 29
    • 0032982736 scopus 로고    scopus 로고
    • Inactivation of the antigen 85C gene profoundly affects the mycolate content and alters the permeability of the Mycobacterium tuberculosis cell envelope
    • March
    • Jackson M., Raynaud C., Laneelle M.A., Guilhot C., Laurent-Winter C., Ensergueix D., et al. Inactivation of the antigen 85C gene profoundly affects the mycolate content and alters the permeability of the Mycobacterium tuberculosis cell envelope. Mol Microbiol 1999, 31(March (5)):1573-1587.
    • (1999) Mol Microbiol , vol.31 , Issue.5 , pp. 1573-1587
    • Jackson, M.1    Raynaud, C.2    Laneelle, M.A.3    Guilhot, C.4    Laurent-Winter, C.5    Ensergueix, D.6
  • 30
    • 0036090968 scopus 로고    scopus 로고
    • Evidence for a partial redundancy of the fibronectin-binding proteins for the transfer of mycoloyl residues onto the cell wall arabinogalactan termini of Mycobacterium tuberculosis
    • May
    • Puech V., Guilhot C., Perez E., Tropis M., Armitige L.Y., Gicquel B., et al. Evidence for a partial redundancy of the fibronectin-binding proteins for the transfer of mycoloyl residues onto the cell wall arabinogalactan termini of Mycobacterium tuberculosis. Mol Microbiol 2002, 44(May (4)):1109-1122.
    • (2002) Mol Microbiol , vol.44 , Issue.4 , pp. 1109-1122
    • Puech, V.1    Guilhot, C.2    Perez, E.3    Tropis, M.4    Armitige, L.Y.5    Gicquel, B.6
  • 31
    • 0037222145 scopus 로고    scopus 로고
    • Mapping of murine Th1 helper T-Cell epitopes of mycolyl transferases Ag85A, Ag85B, and Ag85C from Mycobacterium tuberculosis
    • January
    • D'Souza S., Rosseels V., Romano M., Tanghe A., Denis O., Jurion F., et al. Mapping of murine Th1 helper T-Cell epitopes of mycolyl transferases Ag85A, Ag85B, and Ag85C from Mycobacterium tuberculosis. Infect Immun 2003, 71(January (1)):483-493.
    • (2003) Infect Immun , vol.71 , Issue.1 , pp. 483-493
    • D'Souza, S.1    Rosseels, V.2    Romano, M.3    Tanghe, A.4    Denis, O.5    Jurion, F.6
  • 32
    • 0032924972 scopus 로고    scopus 로고
    • T-cell epitope mapping of the three most abundant extracellular proteins of Mycobacterium tuberculosis in outbred guinea pigs
    • May
    • Lee B.Y., Horwitz M.A. T-cell epitope mapping of the three most abundant extracellular proteins of Mycobacterium tuberculosis in outbred guinea pigs. Infect Immun 1999, 67(May (5)):2665-2670.
    • (1999) Infect Immun , vol.67 , Issue.5 , pp. 2665-2670
    • Lee, B.Y.1    Horwitz, M.A.2
  • 33
    • 0029007258 scopus 로고
    • Mapping of T cell epitopes of the 30-kDa alpha antigen of Mycobacterium bovis strain bacillus Calmette-Guerin in purified protein derivative (PPD)-positive individuals
    • May
    • Silver R.F., Wallis R.S., Ellner J.J. Mapping of T cell epitopes of the 30-kDa alpha antigen of Mycobacterium bovis strain bacillus Calmette-Guerin in purified protein derivative (PPD)-positive individuals. J Immunol 1995, 154(May (9)):4665-4674.
    • (1995) J Immunol , vol.154 , Issue.9 , pp. 4665-4674
    • Silver, R.F.1    Wallis, R.S.2    Ellner, J.J.3
  • 34
    • 57349158670 scopus 로고    scopus 로고
    • Enhanced and enduring protection against tuberculosis by recombinant BCG-Ag85C and its association with modulation of cytokine profile in lung
    • Jain R., Dey B., Dhar N., Rao V., Singh R., Gupta U.D., et al. Enhanced and enduring protection against tuberculosis by recombinant BCG-Ag85C and its association with modulation of cytokine profile in lung. PLoS One 2008, 3(12):e3869.
    • (2008) PLoS One , vol.3 , Issue.12
    • Jain, R.1    Dey, B.2    Dhar, N.3    Rao, V.4    Singh, R.5    Gupta, U.D.6
  • 35
    • 33644761790 scopus 로고    scopus 로고
    • A mycobacterial operon essential for virulence in vivo and invasion and intracellular persistence in macrophages
    • March
    • Gao L.Y., Pak M., Kish R., Kajihara K., Brown E.J. A mycobacterial operon essential for virulence in vivo and invasion and intracellular persistence in macrophages. Infect Immun 2006, 74(March (3)):1757-1767.
    • (2006) Infect Immun , vol.74 , Issue.3 , pp. 1757-1767
    • Gao, L.Y.1    Pak, M.2    Kish, R.3    Kajihara, K.4    Brown, E.J.5
  • 36
    • 0035284904 scopus 로고    scopus 로고
    • Contribution of Th1 and Th2 cells to protection and pathology in experimental models of granulomatous lung disease
    • March
    • Wangoo A., Sparer T., Brown I.N., Snewin V.A., Janssen R., Thole J., et al. Contribution of Th1 and Th2 cells to protection and pathology in experimental models of granulomatous lung disease. J Immunol 2001, 166(March (5)):3432-3439.
    • (2001) J Immunol , vol.166 , Issue.5 , pp. 3432-3439
    • Wangoo, A.1    Sparer, T.2    Brown, I.N.3    Snewin, V.A.4    Janssen, R.5    Thole, J.6
  • 38
    • 0037767314 scopus 로고    scopus 로고
    • The Mycobacterium tuberculosis recombinant 27-kilodalton lipoprotein induces a strong Th1-type immune response deleterious to protection
    • June
    • Hovav A.H., Mullerad J., Davidovitch L., Fishman Y., Bigi F., Cataldi A., et al. The Mycobacterium tuberculosis recombinant 27-kilodalton lipoprotein induces a strong Th1-type immune response deleterious to protection. Infect Immun 2003, 71(June (6)):3146-3154.
    • (2003) Infect Immun , vol.71 , Issue.6 , pp. 3146-3154
    • Hovav, A.H.1    Mullerad, J.2    Davidovitch, L.3    Fishman, Y.4    Bigi, F.5    Cataldi, A.6


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