Antigenic equivalence of human T-cell responses to Mycobacterium tuberculosis-specific RD1-encoded protein antigens ESAT-6 and culture filtrate protein 10 and to mixtures of synthetic peptides

Infection and Immunity

Volumn 68, Issue 6, 2000, Pages 3314-3321

  Arend, Sandra M ^a   Geluk, Annemieke ^a   Van Meijgaarden, Krista E ^a   Van Dissel, Jaap T ^a   Theisen, Michael ^b   Andersen, Peter ^b   Ottenhoff, Tom H M ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^b STATENS SERUM INSTITUT   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGEN PURIFICATION; ANTIGEN RECOGNITION; ARTICLE; HUMAN; HUMAN CELL; IMMUNOSTIMULATION; MYCOBACTERIUM TUBERCULOSIS; PRIORITY JOURNAL; T LYMPHOCYTE; TUBERCULOSIS;

ANTIGENS, BACTERIAL; BACTERIAL PROTEINS; HISTOCOMPATIBILITY TESTING; HLA-DR ANTIGENS; HUMANS; IMMUNOLOGIC TESTS; INTERFERON TYPE II; LYMPHOCYTE ACTIVATION; MYCOBACTERIUM TUBERCULOSIS; PEPTIDES; RECOMBINANT PROTEINS; T-LYMPHOCYTES; TUBERCULOSIS, PULMONARY;

EID: 0034115693     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.68.6.3314-3321.2000     Document Type: Article

References (30)

1. Andersen, P., D. Askgaard, L. Ljungqvist, J. Bennedsen, and I. Heron. 1991. Proteins released from Mycobacterium tuberculosis during growth. Infect. Immun. 59:1905-1910.
2. Anonymous. 1994. Statistical methods in epidemiology, p. 507-534. In P. Armitage and G. Berry (ed.), Statistical methods in medical research. Blackwell Scientific Publications, Oxford, England.
3. Arend, S. M., P. Andersen, K. E. Van Meijgaarden, R. L. V. Skjøt, Y. W. Subronto, J. T. van Dissel, and T. H. M. Ottenhoff. Sensitive and specific detection of active infection with Mycobacterium tuberculosis by human T cell responses to ESAT-6 and CFP-10. J. Infect. Dis., in press.
4. Barnes, P. F., A. B. Bloch, P. T. Davidson, and D. E. Snider, Jr. 1991. Tuberculosis in patients with human immunodeficiency virus infection. N. Engl. J. Med 324:1644-1650.
5. Beardsley, T. 1992. Paradise lost? Microbes mount a comeback as drug resistance spreads. Sci. Am. 267:18-20.
6. Behr, M. A., M. A. Wilson, W. P. Gill, H. Salamon, G. K. Schoolnik, S. Rane, and P. M. Small. 1999. Comparative genomics of BCG vaccines by whole-genome DNA microarray. Science 284:1520-1523.
7. Berthet, F. X., P. B. Rasmussen, I. Rosenkrands, P. Andersen, and B. Gicquel. 1998. A Mycobacterium tuberculosis operon encoding ESAT-6 and a novel low-molecular-mass culture filtrate protein (CPF-10). Microbiology 144:3195-3203.
8. Bothamley, G. H., J. Swanson Beck, G. M. T. Schreuder, J. D'Amaro, R. R. P. De Vries, T. Kardjito, and J. Ivanyi. 1989. Association of tuberculosis and M. tuberculosis-specific antibody levels with HLA. J. Infect. Dis. 159:549-555.
9. Brosch, R., S. V. Gordon, A. Billault, T. Garnier, K. Eiglmeier, C. Soravito, B. G. Barrell, and S. T. Cole. 1998. Use of a Mycobacterium tuberculosis H37Rv bacterial artificial chromosome library for genome mapping, sequencing, and comparative genomics. Infect. Immun. 66:2221-2229.
10. Cole, S. T., R. Brosch, J. Parkhill, T. Garnier, C. Churcher, D. Harris, S. V. Gordon, K. Eiglmeier, S. Gas, C. E. Barry III, F. Tekaia, K. Badcock, D. Basham, D. Brown, T. Chillingworth, R. Connor, R. Davies, K. Devlin, T. Feltwell, S. Gentles, N. Hamlin, S. Holroyd, T. Hornsby, K. Jagels, A. Krogh, J. McLean, S. Moule, L. Murphy, K. Oliver, J. Osborne, M. A. Quail, M.-A. Rajandream, J. Rogers, S. Rutter, K. Seeger, J. Skelton, R. Squares, S. Squares, J. E. Sulston, K. Tayler, S. Whitehead, and B. G. Barrell. 1998. Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence. Nature 393:537-544.
11. Dooley, S. W., W. R. Jarvis, W. J. Martone, and D. E. Snider, Jr. 1992. Multidrug-resistant tuberculosis. Ann. Intern. Med 117:257-258.
12. Edlin, B. R., J. I. G. M. H. Tokars, J. T. Crawford, J. Williams, E. M. Sordillo, K. R. Ong, J. O. Kilburn, S. W. Dooley, K. G. Castro, W. R. Jarvis, and S. D. Holmberg. 1992. An outbreak of multidrug-resistant tuberculosis among hospitalized patients with the acquired immunodeficiency syndrome. N. Engl. J. Med. 326:1514-1521.
13. Gordon, S. V., R. Brosch, A. Billault, T. Garnier, K. Eiglmeier, and S. T. Cole. 1999. Identification of variable regions in the genomes of tubercle bacilli using bacterial artificial chromosome arrays. Mol. Microbiol. 32:643-655.
14. Harboe, M., T. Oettinger, H. G. Wiker, I. Rosenkrands, and P. Andersen. 1996. Evidence for occurrence of the ESAT-6 protein in Mycobacterium tuberculosis and virulent Mycobacterium bovis and for its absence in Mycobacterium bovis BCG. Infect. Immun. 64:16-22.
15. Huebner, R. E., M. F. Schein, and J. B. Bass, Jr. 1993. The tuberculin skin test. Clin. Infect. Dis. 17:968-975.
16. Jurcevic, S., A. Hills, G. Pasvol, R. N. Davidson, J. Ivanyi, and R. J. Wilkinson. 1996. T cell responses to a mixture of Mycobacterium tuberculosis peptides with complementary HLA-DR binding profiles. Clin. Exp. Immunol. 105:416-421.
17. Lein, A. D., C. F. von Reyn, P. Ravn, C. R. Horsburgh, Jr., L. N. Alexander, and P. Andersen. 1999. Cellular immune responses to ESAT-6 discriminate between patients with pulmonary disease due to Mycobacterium avium complex and those with pulmonary disease due to Mycobacterium tuberculosis. Clin. Diagn. Lab. Immunol. 6:606-609.
18. Mahairas, G. G., P. J. Sabo, M. J. Hickey, D. C. Singh, and C. K. Stover. 1996. Molecular analysis of genetic differences between Mycobacterium bovis BCG and virulent M. bovis. J. Bacteriol. 178:1274-1282.
19. Mustafa, A. S., H. A. Amoudy, H. G. Wiker, A. T. Abal, P. Ravn, F. Oftung, and P. Andersen. 1998. Comparison of antigen-specific T-cell responses of tuberculosis patients using complex or single antigens of Mycobacterium tuberculosis. Scand. J. Immunol. 48:535-543.
20. Ottenhoff, T. H. M., D. G. Elferink, J. Hermans, and R. R. P. De Vries. 1985. HLA class II restriction repertoire of antigen-specific T cells. I. The main restriction determinants for antigen presentation are associated with HLA-D/DR and not with DP and DQ. Hum. Immunol. 13:105-116.
21. Ravn, P., A. Demissie, T. Eguale, H. Woodwosson, D. Lein, H. A. Amoudy, A. S. Mustafa, A. K. Jensen, A. Holm, I. Rosenkrands, F. Oftung, J. Olobo, F. von Reyn, and P. Andersen. 1999. Human T cell responses to the ESAT-6 antigen from Mycobacterium tuberculosis. J. Infect. Dis. 179:637-645.
22. Selvaraj, P., H. Uma, A. M. Reetha, T. Xavier, R. Prabhakar, and P. R. Narayanan. 1998. Influence of HLA-DR2 phenotype on humoral & lymphocyte response to Mycobacterium tuberculosis culture filtrate antigens in pulmonary tuberculosis. Indian J. Med. Res. 107:208-217.
23. Skjøt, R. L. V., T. Oettinger, I. Rosenkrands, P. Ravn, I. Brock, S. Jacobsen, and P. Andersen. 2000. Comparative evaluation of low-molecular-mass proteins from Mycobacterium tuberculosis identifies members of the ESAT-6 family as immunodominant T-cell antigens. Infect. Immun. 68:214-220.
24. Sørensen, A. L., S. Nagai, G. Houen, P. Andersen, and Å. B. Andersen. 1995. Purification and characterization of a low-molecular-mass T-cell antigen secreted by Mycobacterium tuberculosis. Infect. Immun. 63:1710-1717.
25. Ulrichs, T., M. E. Munk, H. Mollenkopf, S. Behr-Perst, R. Colangeli, M. L. Gennaro, and S. H. E. Kaufmann. 1998. Differential T cell responses to Mycobacterium tuberculosis ESAT6 in tuberculosis patients and healthy donors. Eur. J. Immunol. 28:3949-3958.
26. van Pinxteren, L. A. H., P. Ravn, E. M. Agger, J. M. Pollock, and P. Andersen. 2000. Diagnosis of tuberculosis based on the two specific antigens ESAT-6 and CFP10. Clin. Diagn. Lab. Immunol. 7:155-160.
27. Vordermeier, H. M., P. C. Cockle, A. Whelan, S. Rhodes, N. Palmer, D. Bakker, and R. G. Hewinson. 1999. Development of diagnostic reagents to differentiate between Mycobacterium bovis BCG vaccination and M. bovis infection in cattle. Clin. Diagn. Lab. Immunol. 6:675-682.
28. Wilkinson, R. J., K. Hasløv, R. Rappuoli, F. Giovannoni, P. R. Narayanan, C. R. Desai, H. M. Vordermeier, J. Paulsen, G. Pasvol, J. Ivanyi, and M. Singh. 1997. Evaluation of the recombinant 38-kilodalton antigen of Mycobacterium tuberculosis as a potential immunodiagnostic reagent. J. Clin. Microbiol. 35:553-557.
29. Wilkinson, R. J., H. M. Vordermeier, K. A. Wilkinson, A. Sjölund, C. Moreno, G. Pasvol, and J. Ivanyi. 1998. Peptide-specific T cell responses to Mycobacterium tuberculosis: clinical spectrum, compartmentalization, and effect of chemotherapy. J. Infect. Dis. 178:760-768.
30. Young, D. B., and T. R. Garbe. 1998. Heat shock proteins and antigens of Mycobacterium tuberculosis. Infect. Immun. 59:3086-3093.