A novel DNA vaccine containing multiple TB-specific epitopes casted in a natural structure (ECANS) confers protective immunity against pulmonary mycobacterial challenge

Vaccine

Volumn 27, Issue 39, 2009, Pages 5313-5319

  Gao, Haifeng ^a   Yue, Yan ^a   Hu, Linkun ^a   Xu, Wei ^a   Xiong, Sidong ^a  

^a FUDAN UNIVERSITY   (China)

Author keywords

DNA vaccine; ECANS; Epitope; Mycobacterium tuberculosis

Indexed keywords

DNA VACCINE; EARLY SECRETORY ANTIGENIC TARGET 6; EPITOPE; GAMMA INTERFERON; HEAT SHOCK PROTEIN 65; IMMUNOGLOBULIN G1; IMMUNOGLOBULIN G2A; INTERLEUKIN 2;

ADOLESCENT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BAGG ALBINO MOUSE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOTOXIC T LYMPHOCYTE; DNA IMMUNIZATION; DRUG POTENCY; FEMALE; GENE INSERTION; HUMAN; HUMAN CELL; IMMUNE RESPONSE; IMMUNITY; IMMUNOGENICITY; LUNG TUBERCULOSIS; MOUSE; MYCOBACTERIUM BOVIS; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PLASMID; PRIORITY JOURNAL; TH1 CELL;

ANIMALS; ANTIBODIES, BACTERIAL; ANTIGENS, BACTERIAL; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CELL LINE; EPITOPES, T-LYMPHOCYTE; FEMALE; HUMANS; INTERFERON-GAMMA; INTERLEUKIN-12; MICE; MICE, INBRED BALB C; MYCOBACTERIUM TUBERCULOSIS; TUBERCULOSIS VACCINES; TUBERCULOSIS, PULMONARY; VACCINES, DNA;

EID: 68349101256     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vaccine.2009.06.093     Document Type: Article

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