Expression of the B-cell and T-cell epitopes of the rabies virus nucleoprotein in Mycobacterium bovis BCG and induction of an humoral response in mice

Vaccine

Volumn 20, Issue 5-6, 2001, Pages 731-736

  Da Cruz, Flávia W ^a,b   McBride, Alan J A ^a,b   Conceição, Fabrício R ^a   Dale, Jeremy W ^b   McFadden, Johnjoe ^b   Dellagostin, Odir A ^a  

^a University of Pelotas   (Brazil)

^b UNIVERSITY OF SURREY   (United Kingdom)

Author keywords

Mycobacterium bovis; Rabies vaccine; Recombinant BCG

Indexed keywords

BCG VACCINE; EPITOPE; HEAT SHOCK PROTEIN 60; RABIES VACCINE; RECOMBINANT VACCINE; VIRUS NUCLEOPROTEIN;

ANIMAL EXPERIMENT; ANTIBODY TITER; ARTICLE; BACTERIAL GENE; BACTERIUM CULTURE; CLONING; CONTROLLED STUDY; DRUG RESPONSE; EXPRESSION VECTOR; HOST; HUMORAL IMMUNITY; IMMUNE SYSTEM; IMMUNIZATION; IN VIVO STUDY; MALE; MOUSE; MYCOBACTERIUM BOVIS; MYCOBACTERIUM LEPRAE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; RABIES VIRUS;

ANIMALS; ANTIBODIES, VIRAL; ANTIGENS, VIRAL; B-LYMPHOCYTES; BASE SEQUENCE; EPITOPES; GENE EXPRESSION; GENETIC VECTORS; MALE; MICE; MICE, INBRED BALB C; MYCOBACTERIUM BOVIS; NUCLEOCAPSID; NUCLEOCAPSID PROTEINS; PLASMIDS; RABIES VACCINES; RABIES VIRUS; T-LYMPHOCYTES; VACCINES, SYNTHETIC;

EID: 0035852333     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0264-410X(01)00414-5     Document Type: Article

References (38)

1. Vaccines for the third world
2. New use of BCG for recombinant vaccines
3. Development of BCG as a recombinant vaccine vehicle
4. Functional analysis of, pAL5000 a plasmid from Mycobacterium fortuitum: Construction of a mini Mycobacterium-Escherichia coli shuttle vector
5. Establishment of a foreign antigen secretion system in mycobacteria
6. Humoral and cell-mediated immune responses to live recombinant BCG-HIV vaccines
7. Expression of heterologous genes in Mycobacterium bovis BCG: Induction of a cellular response against HIV-1 Nef protein
8. Construction and use of integrative vectors to express foreign genes in mycobacteria
9. Stable integration and expression of the Plasmodium falciparum circumsporozoite protein coding sequence in mycobacteria
10. Neutralizing antibody responses elicited in mice immunised with recombinant Bacillus Calmette-Guérin producing the Schistosoma mansoni glutathione-S-transferase
11. Recombinant BCG expressing the Leishmania surface antigen Gp63 induces protective immunity against Leishmania major infection in BALB/c mice
12. Systemic and mucosal immunity induced by BCG vector expressing outer-surface protein A of Borrelia burgdorferi
13. Humoral and cellular immune responses in mice immunised with recombinant Mycobacterium bovis Bacillus Calmette-Guérin producing a pertussis toxin-tetanus toxin hybrid protein
14. Recombinant Mycobacterium bovis Bacillus Calmette-Guérin secreting merozoite surface protein 1 (MSP-1) induces protection against rodent malaria parasite infection depending on MSP-1-stimulated interferon gamma and parasite-specific antibodies
15. Antigenic proteins of M. leprae: Complete sequence of the gene for the 18-kDa protein
16. Characterisation of a novel Lyssavirus isolated from Ptroptid bats in Australia
17. Economic losses due to Desmodus rotundus
18. Rabies: A review
19. Rabies virus glycoprotein. II. Biological and serological characterization
20. Immunogenic properties of vaccinia recombinant virus expressing the rabies glycoprotein
21. Recombinant rabies vaccines: Efficacy assessment in free-ranging animals
22. Experimental rabies infection and oral vaccination in vampire bats (Desmodus rotundus)
23. Rabies oral vaccination of foxes during the summer with the VRG vaccine bait
24. Antigenic variation in rabies and rabies-related viruses: Cross-protection independent of glycoprotein-mediated virus neutralizing antibody
25. Conserved nucleotide sequence of rabies virus cDNA encoding the nucleoprotein
26. Localization and immunological characterization of antigenic domains of the rabies virus internal N and NS proteins
27. Raccoon poxvirus recombinants expressing the rabies virus nucleoprotein protect mice against lethal rabies virus infection
28. Protection of mice with vaccinia virus recombinants that express the rabies nucleoprotein
29. Rabies virus nucleoprotein expressed in and purified from insect cells is efficacious as a vaccine
30. Linear and conformation-dependent antigenic sites on the nucleoprotein of rabies virus
31. Expression of the nucleoprotein of rabies virus in Escherichia coli and mapping of antigenic sites
32. Induction of rabies virus specific T-helper cells by synthetic peptides that carry dominant T-helper cell epitopes of the viral ribonucleoprotein
33. Genetic systems for the mycobacteria
34. Bacterial vaccine vectors and Bacillus Calmette-Guérin
35. Immunoprotection by rabies virus nucleoprotein
36. Activity of mycobacterial promoters during intracellular and extracellular growth
37. Restriction endonuclease mapping and cloning of Mycobacterium fortuitum var. Fortuitum plasmid pAL5000