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Volumn 58, Issue 2, 2010, Pages 121-130

CD4+ T cell epitope discovery and rational vaccine design

Author keywords

CD4+ T cells; Epitope prediction; Epitope based vaccines; T cell help; Vaccine design

Indexed keywords

EPITOPE; INTERLEUKIN 12; INTERLEUKIN 15; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; VACCINE;

EID: 77952762373     PISSN: 0004069X     EISSN: 16614917     Source Type: Journal    
DOI: 10.1007/s00005-010-0067-0     Document Type: Review
Times cited : (61)

References (91)
  • 2
    • 39249084174 scopus 로고    scopus 로고
    • In silico identification and in vivo analysis of a novel T-cell antigen from Chlamydia, NrdB
    • 10.1016/j.vaccine.2007.12.048 1:CAS:528:DC%2BD1cXitlemtrc%3D 18261829
    • CJ Barker KW Beagley LM Hafner, et al. 2008 In silico identification and in vivo analysis of a novel T-cell antigen from Chlamydia, NrdB Vaccine 26 1285 1296 10.1016/j.vaccine.2007.12.048 1:CAS:528:DC%2BD1cXitlemtrc%3D 18261829
    • (2008) Vaccine , vol.26 , pp. 1285-1296
    • Barker, C.J.1    Beagley, K.W.2    Hafner, L.M.3
  • 3
    • 0032482356 scopus 로고    scopus 로고
    • Help for cytotoxic-T-cell responses is mediated by CD40 signalling
    • DOI 10.1038/30996
    • SR Bennett FR Carbone F Karamalis, et al. 1998 Help for cytotoxic-T-cell responses is mediated by CD40 signalling Nature 393 478 480 10.1038/30996 1:CAS:528:DyaK1cXjs1Kmtro%3D 9624004 (Pubitemid 28292195)
    • (1998) Nature , vol.393 , Issue.6684 , pp. 478-480
    • Bennett, S.R.M.1    Carbone, F.R.2    Karamalis, F.3    Flaveli, R.A.4    Miller, J.F.A.P.5    Heath, W.R.6
  • 4
    • 0023919479 scopus 로고
    • Immunodominance in T lymphocyte recognition
    • 10.1016/0165-2478(88)90046-6 1:CAS:528:DyaL1cXkvFSktbs%3D 3042616
    • JA Berzofsky 1988 Immunodominance in T lymphocyte recognition Immunol Lett 18 83 92 10.1016/0165-2478(88)90046-6 1:CAS:528:DyaL1cXkvFSktbs%3D 3042616
    • (1988) Immunol Lett , vol.18 , pp. 83-92
    • Berzofsky, J.A.1
  • 5
    • 0023162534 scopus 로고
    • Protein antigenic structures recognized by T cells: Potential applications to vaccine design
    • 10.1111/j.1600-065X.1987.tb00518.x 1:CAS:528:DyaL2sXmtlChurg%3D 2443443
    • JA Berzofsky KB Cease JL Cornette, et al. 1987 Protein antigenic structures recognized by T cells: potential applications to vaccine design Immunol Rev 98 9 52 10.1111/j.1600-065X.1987.tb00518.x 1:CAS:528: DyaL2sXmtlChurg%3D 2443443
    • (1987) Immunol Rev , vol.98 , pp. 9-52
    • Berzofsky, J.A.1    Cease, K.B.2    Cornette, J.L.3
  • 6
    • 3543099130 scopus 로고    scopus 로고
    • Helping the CD8(+) T-cell response
    • 10.1038/nri1413 1:CAS:528:DC%2BD2cXmtFWktro%3D 15286726
    • MJ Bevan 2004 Helping the CD8(+) T-cell response Nat Rev Immunol 4 595 602 10.1038/nri1413 1:CAS:528:DC%2BD2cXmtFWktro%3D 15286726
    • (2004) Nat Rev Immunol , vol.4 , pp. 595-602
    • Bevan, M.J.1
  • 7
    • 7944224384 scopus 로고    scopus 로고
    • Discovery of promiscuous HLA-II-restricted T cell epitopes with TEPITOPE
    • DOI 10.1016/j.ymeth.2004.06.002, PII S104620230400129X, Bioinformatics in Vaccine Design
    • H Bian J Hammer 2004 Discovery of promiscuous HLA-II-restricted T cell epitopes with TEPITOPE Methods 34 468 475 10.1016/j.ymeth.2004.06.002 1:CAS:528:DC%2BD2cXpslCrtbg%3D 15542373 (Pubitemid 39469054)
    • (2004) Methods , vol.34 , Issue.4 , pp. 468-475
    • Bian, H.1    Hammer, J.2
  • 8
    • 0023187442 scopus 로고
    • The foreign antigen binding site and T cell recognition regions of class I histocompatibility antigens
    • DOI 10.1038/329512a0
    • PJ Bjorkman MA Saper B Samraoui, et al. 1987 The foreign antigen binding site and T cell recognition regions of class I histocompatibility antigens Nature 329 512 518 10.1038/329512a0 1:CAS:528:DyaL2sXmtlCguro%3D 2443855 (Pubitemid 17131094)
    • (1987) Nature , vol.329 , Issue.6139 , pp. 512-518
    • Bjorkman, P.J.1    Saper, M.A.2    Samroui, B.3
  • 9
    • 33746642628 scopus 로고    scopus 로고
    • From functional genomics to functional immunomics: New challenges, old problems, big rewards
    • DOI 10.1371/journal.pcbi.0020081
    • UM Braga-Neto ET Marques Jr 2006 From functional genomics to functional immunomics: new challenges, old problems, big rewards PLoS Comput Biol 2 e81 10.1371/journal.pcbi.0020081 16863395 (Pubitemid 44147377)
    • (2006) PLoS Computational Biology , vol.2 , Issue.7 , pp. 0651-0662
    • Braga-Neto, U.M.1    Marques Jr., E.T.A.2
  • 10
    • 36048970545 scopus 로고    scopus 로고
    • + T cell epitopes from vaccinia virus induced by vaccination or infection
    • DOI 10.1371/journal.ppat.0030144
    • JM Calvo-Calle I Strug MD Nastke, et al. 2007 Human CD4+ T cell epitopes from vaccinia virus induced by vaccination or infection PLoS Pathog 3 1511 1529 10.1371/journal.ppat.0030144 1:CAS:528:DC%2BD2sXhsVOgu7jF 17937498 (Pubitemid 350085615)
    • (2007) PLoS Pathogens , vol.3 , Issue.10 , pp. 1511-1529
    • Calvo-Calle, J.M.1    Strug, I.2    Nastke, M.-D.3    Baker, S.P.4    Stern, L.J.5
  • 11
    • 0030802693 scopus 로고    scopus 로고
    • T cell receptor recognition of MHC class II-bound peptide flanking residues enhances immunogenicity and results in altered TCR V region usage
    • DOI 10.1016/S1074-7613(00)80360-X
    • RT Carson KM Vignali DL Woodland, et al. 1997 T cell receptor recognition of MHC class II-bound peptide flanking residues enhances immunogenicity and results in altered TCR V region usage Immunity 7 387 399 10.1016/S1074-7613(00) 80360-X 1:CAS:528:DyaK2sXmsFKjtrY%3D 9324359 (Pubitemid 27446013)
    • (1997) Immunity , vol.7 , Issue.3 , pp. 387-399
    • Carson, R.T.1    Vignali, K.M.2    Woodland, D.L.3    Vignali, D.A.A.4
  • 12
    • 33645982242 scopus 로고    scopus 로고
    • Scanning the HIV genome for CD4+ T cell epitopes restricted to HLA-DP4, the most prevalent HLA class II molecule
    • 1:CAS:528:DC%2BD28XjsFansrw%3D 16622007
    • WM Cohen S Pouvelle-Moratille XF Wang, et al. 2006 Scanning the HIV genome for CD4+ T cell epitopes restricted to HLA-DP4, the most prevalent HLA class II molecule J Immunol 176 5401 5408 1:CAS:528:DC%2BD28XjsFansrw%3D 16622007
    • (2006) J Immunol , vol.176 , pp. 5401-5408
    • Cohen, W.M.1    Pouvelle-Moratille, S.2    Wang, X.F.3
  • 13
    • 0033073766 scopus 로고    scopus 로고
    • MHC-restricted antigen presentation and recognition: Constraints on gene, recombinant and peptide vaccines in humans
    • 10.1590/S0100-879X1999000200008 1:CAS:528:DyaK1MXhslOls7k%3D 10347755
    • E Cunha-Neto 1999 MHC-restricted antigen presentation and recognition: constraints on gene, recombinant and peptide vaccines in humans Braz J Med Biol Res 32 199 205 10.1590/S0100-879X1999000200008 1:CAS:528:DyaK1MXhslOls7k%3D 10347755
    • (1999) Braz J Med Biol Res , vol.32 , pp. 199-205
    • Cunha-Neto, E.1
  • 14
    • 23244448155 scopus 로고    scopus 로고
    • T cell recognition and cytokine profile induced by melanocyte epitopes in HLA-DRB1 0405-positive and negative Vogt-Koyanagi-Harada uveitis patients
    • Damico FM, Cunha-Neto E, Goldberg AC, Iwai LK, Marin ML, Hammer J, Kalil J, Yamamoto JH (2005) T cell recognition and cytokine profile induced by melanocyte epitopes in HLA-DRB1 0405-positive and negative Vogt-Koyanagi-Harada uveitis patients. Invest Ophthalmol Vis Sci 46:2465-2471
    • (2005) Invest Ophthalmol Vis Sci , vol.46 , pp. 2465-2471
    • Damico, F.M.1    Cunha-Neto, E.2    Goldberg, A.C.3    Iwai, L.K.4    Marin, M.L.5    Hammer, J.6    Kalil, J.7    Yamamoto, J.H.8
  • 15
    • 0029686592 scopus 로고    scopus 로고
    • Reverse immunogenetics: From HLA-disease associations to vaccine candidates
    • DOI 10.1016/1357-4310(96)88757-0
    • MP Davenport AV Hill 1996 Reverse immunogenetics: from HLA-disease associations to vaccine candidates Mol Med Today 2 38 45 10.1016/1357-4310(96) 88757-0 1:CAS:528:DyaK28XhsFSktbg%3D 8796850 (Pubitemid 126408246)
    • (1996) Molecular Medicine Today , vol.2 , Issue.1 , pp. 38-45
    • Davenport, M.P.1    Hill, A.V.S.2
  • 16
    • 0030890660 scopus 로고    scopus 로고
    • An interactive web site providing major histocompatibility ligand predictions: Application to HIV research
    • 10.1089/aid.1997.13.529 9135870
    • AS De Groot BM Jesdale E Szu, et al. 1997 An interactive web site providing major histocompatibility ligand predictions: application to HIV research AIDS Res Hum Retrovir 13 529 531 10.1089/aid.1997.13.529 9135870
    • (1997) AIDS Res Hum Retrovir , vol.13 , pp. 529-531
    • De Groot, A.S.1    Jesdale, B.M.2    Szu, E.3
  • 18
    • 54849437047 scopus 로고    scopus 로고
    • Prediction of immunogenicity: In silico paradigms, ex vivo and in vivo correlates
    • 10.1016/j.coph.2008.08.002 18775515
    • AS De Groot J McMurry L Moise 2008 Prediction of immunogenicity: in silico paradigms, ex vivo and in vivo correlates Curr Opin Pharmacol 8 620 626 10.1016/j.coph.2008.08.002 18775515
    • (2008) Curr Opin Pharmacol , vol.8 , pp. 620-626
    • De Groot, A.S.1    McMurry, J.2    Moise, L.3
  • 19
    • 0033566811 scopus 로고    scopus 로고
    • Cutting edge: Identification of novel T cell epitopes in Lol p5a by computational prediction
    • 10438899
    • C de Lalla T Sturniolo L Abbruzzese, et al. 1999 Cutting edge: identification of novel T cell epitopes in Lol p5a by computational prediction J Immunol 163 1725 1729 10438899
    • (1999) J Immunol , vol.163 , pp. 1725-1729
    • De Lalla, C.1    Sturniolo, T.2    Abbruzzese, L.3
  • 21
    • 0034661982 scopus 로고    scopus 로고
    • HLA-DR-promiscuous T cell epitopes from plasmodium falciparum pre-erythrocytic-stage antigens restricted by multiple HLA class II alleles
    • 1:CAS:528:DC%2BD3cXkvFWitLs%3D 10878392
    • DL Doolan S Southwood R Chesnut, et al. 2000 HLA-DR-promiscuous T cell epitopes from plasmodium falciparum pre-erythrocytic-stage antigens restricted by multiple HLA class II alleles J Immunol 165 1123 1137 1:CAS:528: DC%2BD3cXkvFWitLs%3D 10878392
    • (2000) J Immunol , vol.165 , pp. 1123-1137
    • Doolan, D.L.1    Southwood, S.2    Chesnut, R.3
  • 22
    • 4944223135 scopus 로고    scopus 로고
    • Pathogenic human thyroglobulin peptides in HLA-DR3 transgenic mouse model of autoimmune thyroiditis
    • DOI 10.1016/j.cellimm.2004.07.002, PII S0008874904001157
    • JC Flynn DJ McCormick V Brusic, et al. 2004 Pathogenic human thyroglobulin peptides in HLA-DR3 transgenic mouse model of autoimmune thyroiditis Cell Immunol 229 79 85 10.1016/j.cellimm.2004.07.002 1:CAS:528:DC%2BD2cXotlSmtbY%3D 15474522 (Pubitemid 39330215)
    • (2004) Cellular Immunology , vol.229 , Issue.2 , pp. 79-85
    • Flynn, J.C.1    McCormick, D.J.2    Brusic, V.3    Wan, Q.4    Panos, J.C.5    Giraldo, A.A.6    David, C.S.7    Kong, Y.-C.M.8
  • 23
    • 15244354759 scopus 로고    scopus 로고
    • Human T cell epitope mapping of the Schistosoma mansoni 14-kDa fatty acid-binding protein using cells from patients living in areas endemic for schistosomiasis
    • DOI 10.1016/j.micinf.2004.10.012
    • CT Fonseca E Cunha-Neto AC Goldberg, et al. 2005 Human T cell epitope mapping of the Schistosoma mansoni 14 kDa fatty acid-binding protein using cells from patients living in areas endemic for schistosomiasis Microbes Infect 7 204 212 10.1016/j.micinf.2004.10.012 1:CAS:528:DC%2BD2MXisFKjurs%3D 15725385 (Pubitemid 40387424)
    • (2005) Microbes and Infection , vol.7 , Issue.2 , pp. 204-212
    • Fonseca, C.T.1    Cunha-Neto, E.2    Goldberg, A.C.3    Kalil, J.4    De Jesus, A.R.5    Carvalho, E.M.6    Correa-Oliveira, R.7    Oliveira, S.C.8
  • 24
    • 28344456594 scopus 로고    scopus 로고
    • Identification of paramyosin T cell epitopes associated with human resistance to Schistosoma mansoni infection
    • 1:CAS:528:DC%2BD2MXhtlWqtrvM 16297167
    • CT Fonseca E Cunha-Neto AC Goldberg, et al. 2005 Identification of paramyosin T cell epitopes associated with human resistance to Schistosoma mansoni infection Clin Exp Immunol 142 539 547 1:CAS:528:DC%2BD2MXhtlWqtrvM 16297167
    • (2005) Clin Exp Immunol , vol.142 , pp. 539-547
    • Fonseca, C.T.1    Cunha-Neto, E.2    Goldberg, A.C.3
  • 26
    • 0029120420 scopus 로고
    • Viral mutations, TCR antagonism and escape from the immune response
    • 10.1016/0952-7915(95)80098-0 1:CAS:528:DyaK2MXotF2ks7k%3D 7495517
    • A Franco C Ferrari A Sette, et al. 1995 Viral mutations, TCR antagonism and escape from the immune response Curr Opin Immunol 7 524 531 10.1016/0952-7915(95)80098-0 1:CAS:528:DyaK2MXotF2ks7k%3D 7495517
    • (1995) Curr Opin Immunol , vol.7 , pp. 524-531
    • Franco, A.1    Ferrari, C.2    Sette, A.3
  • 27
    • 0030999062 scopus 로고    scopus 로고
    • Protective cellular immunity: Cytotoxic T-lymphocyte responses against dominant and recessive epitopes of influenza virus nucleoprotein induced by DNA immunization
    • 1:CAS:528:DyaK2sXhvVCqu74%3D 9060624
    • TM Fu A Friedman JB Ulmer, et al. 1997 Protective cellular immunity: cytotoxic T-lymphocyte responses against dominant and recessive epitopes of influenza virus nucleoprotein induced by DNA immunization J Virol 71 2715 2721 1:CAS:528:DyaK2sXhvVCqu74%3D 9060624
    • (1997) J Virol , vol.71 , pp. 2715-2721
    • Fu, T.M.1    Friedman, A.2    Ulmer, J.B.3
  • 28
    • 0036182416 scopus 로고    scopus 로고
    • Immunologic control of HIV-1
    • DOI 10.1146/annurev.med.53.082901.104011
    • RT Gandhi BD Walker 2002 Immunologic control of HIV-1 Annu Rev Med 53 149 172 10.1146/annurev.med.53.082901.104011 1:CAS:528:DC%2BD38Xitl2mtr4%3D 11818468 (Pubitemid 34177876)
    • (2002) Annual Review of Medicine , vol.53 , pp. 149-172
    • Gandhi, R.T.1    Walker, B.D.2
  • 29
    • 43849112632 scopus 로고    scopus 로고
    • Peptides containing T cell epitopes, derived from Sm14, but not from paramyosin, induce a Th1 type of immune response, reduction in liver pathology and partial protection against Schistosoma mansoni infection in mice
    • 10.1016/j.actatropica.2008.03.003 1:CAS:528:DC%2BD1cXmt1Ois7Y%3D 18423420
    • TC Garcia CT Fonseca LG Pacifico, et al. 2008 Peptides containing T cell epitopes, derived from Sm14, but not from paramyosin, induce a Th1 type of immune response, reduction in liver pathology and partial protection against Schistosoma mansoni infection in mice Acta Trop 106 162 167 10.1016/j. actatropica.2008.03.003 1:CAS:528:DC%2BD1cXmt1Ois7Y%3D 18423420
    • (2008) Acta Trop , vol.106 , pp. 162-167
    • Garcia, T.C.1    Fonseca, C.T.2    Pacifico, L.G.3
  • 30
    • 38649118833 scopus 로고    scopus 로고
    • In silico tools for predicting peptides binding to HLA-class II molecules: More confusion than conclusion
    • DOI 10.1021/pr070527b
    • U Gowthaman JN Agrewala 2008 In silico tools for predicting peptides binding to HLA-class II molecules: more confusion than conclusion J Proteome Res 7 154 163 10.1021/pr070527b 1:CAS:528:DC%2BD2sXhtlCqtLnL 18034454 (Pubitemid 351171127)
    • (2008) Journal of Proteome Research , vol.7 , Issue.1 , pp. 154-163
    • Gowthaman, U.1    Agrewala, J.N.2
  • 31
    • 7944237425 scopus 로고    scopus 로고
    • MHCPred: Bringing a quantitative dimension to the online prediction of MHC binding
    • 1:CAS:528:DC%2BD3sXotVOrtb8%3D 15130834
    • P Guan IA Doytchinova C Zygouri, et al. 2003 MHCPred: bringing a quantitative dimension to the online prediction of MHC binding Appl Bioinformatics 2 63 66 1:CAS:528:DC%2BD3sXotVOrtb8%3D 15130834
    • (2003) Appl Bioinformatics , vol.2 , pp. 63-66
    • Guan, P.1    Doytchinova, I.A.2    Zygouri, C.3
  • 33
    • 0027937713 scopus 로고
    • Precise prediction of major histocompatibility complex class II-peptide interaction based on peptide side chain scanning
    • DOI 10.1084/jem.180.6.2353
    • J Hammer E Bono F Gallazzi, et al. 1994 Precise prediction of major histocompatibility complex class II-peptide interaction based on peptide side chain scanning J Exp Med 180 2353 2358 10.1084/jem.180.6.2353 1:CAS:528:DyaK2cXmsFeiur8%3D 7964508 (Pubitemid 24351618)
    • (1994) Journal of Experimental Medicine , vol.180 , Issue.6 , pp. 2353-2358
    • Hammer, J.1    Bono, E.2    Gallazzi, F.3    Belunis, C.4    Nagy, Z.5    Sinigaglia, F.6
  • 34
    • 0030665681 scopus 로고    scopus 로고
    • Strategies for identifying and predicting islet autoantigen T-cell epitopes in insulin-dependent diabetes mellitus
    • 10.3109/07853899708999369 1:CAS:528:DyaK1cXmtV2lug%3D%3D 9453287
    • MC Honeyman V Brusic LC Harrison 1997 Strategies for identifying and predicting islet autoantigen T-cell epitopes in insulin-dependent diabetes mellitus Ann Med 29 401 404 10.3109/07853899708999369 1:CAS:528: DyaK1cXmtV2lug%3D%3D 9453287
    • (1997) Ann Med , vol.29 , pp. 401-404
    • Honeyman, M.C.1    Brusic, V.2    Harrison, L.C.3
  • 35
    • 0036644723 scopus 로고    scopus 로고
    • Identification of naturally processed CD4 T cell epitopes from the prostate-specific antigen kallikrein 4 using peptide based in vitro stimulation
    • 1:CAS:528:DC%2BD38XltVKitr8%3D 12077288
    • JA Hural RS Friedman A McNabb, et al. 2002 Identification of naturally processed CD4 T cell epitopes from the prostate-specific antigen kallikrein 4 using peptide based in vitro stimulation J Immunol 169 557 565 1:CAS:528:DC%2BD38XltVKitr8%3D 12077288
    • (2002) J Immunol , vol.169 , pp. 557-565
    • Hural, J.A.1    Friedman, R.S.2    McNabb, A.3
  • 36
    • 33744955355 scopus 로고    scopus 로고
    • Thyrotropin receptor epitopes and their relation to histocompatibility leukocyte antigen-DR molecules in graves' disease
    • DOI 10.1210/jc.2005-2537
    • H Inaba W Martin AS De Groot, et al. 2006 Thyrotropin receptor epitopes and their relation to histocompatibility leukocyte antigen-DR molecules in Graves' disease J Clin Endocrinol Metab 91 2286 2294 10.1210/jc.2005-2537 1:CAS:528:DC%2BD28XlvVCgtr0%3D 16595602 (Pubitemid 43855019)
    • (2006) Journal of Clinical Endocrinology and Metabolism , vol.91 , Issue.6 , pp. 2286-2294
    • Inaba, H.1    Martin, W.2    De Groot, A.S.3    Qin, S.4    De Groot, L.J.5
  • 37
    • 3042700384 scopus 로고    scopus 로고
    • In silico prediction of peptides binding to multiple HLA-DR molecules accurately identifies immunodominant epitopes from gp43 of Paracoccidioides brasiliensis frequently recognized in primary peripheral blood mononuclear cell responses from sensitized individuals
    • 1:CAS:528:DC%2BD2cXmtFyhu7o%3D 15208742
    • LK Iwai M Yoshida J Sidney, et al. 2003 In silico prediction of peptides binding to multiple HLA-DR molecules accurately identifies immunodominant epitopes from gp43 of Paracoccidioides brasiliensis frequently recognized in primary peripheral blood mononuclear cell responses from sensitized individuals Mol Med 9 209 219 1:CAS:528:DC%2BD2cXmtFyhu7o%3D 15208742
    • (2003) Mol Med , vol.9 , pp. 209-219
    • Iwai, L.K.1    Yoshida, M.2    Sidney, J.3
  • 40
    • 1342345784 scopus 로고    scopus 로고
    • CD4 T cell-dependent CD8 T cell maturation
    • 1:CAS:528:DC%2BD2cXhsVCrsrg%3D 14978084
    • A Khanolkar MJ Fuller AJ Zajac 2004 CD4 T cell-dependent CD8 T cell maturation J Immunol 172 2834 2844 1:CAS:528:DC%2BD2cXhsVCrsrg%3D 14978084
    • (2004) J Immunol , vol.172 , pp. 2834-2844
    • Khanolkar, A.1    Fuller, M.J.2    Zajac, A.J.3
  • 41
    • 35348879703 scopus 로고    scopus 로고
    • CD8 T cell memory development: CD4 T cell help is appreciated
    • DOI 10.1007/s12026-007-0081-4
    • A Khanolkar VP Badovinac JT Harty 2007 CD8 T cell memory development: CD4 T cell help is appreciated Immunol Res 39 94 104 10.1007/s12026-007-0081-4 1:CAS:528:DC%2BD2sXhtlertbnK 17917058 (Pubitemid 47574900)
    • (2007) Immunologic Research , vol.39 , Issue.1-3 , pp. 94-104
    • Khanolkar, A.1    Badovinac, V.P.2    Harty, J.T.3
  • 42
    • 45549084113 scopus 로고    scopus 로고
    • Enhancement of DNA vaccine potency through coadministration of CIITA DNA with DNA vaccines via gene gun
    • 1:CAS:528:DC%2BD1cXltlCrs7o%3D 18453624
    • D Kim T Hoory A Monie, et al. 2008 Enhancement of DNA vaccine potency through coadministration of CIITA DNA with DNA vaccines via gene gun J Immunol 180 7019 7027 1:CAS:528:DC%2BD1cXltlCrs7o%3D 18453624
    • (2008) J Immunol , vol.180 , pp. 7019-7027
    • Kim, D.1    Hoory, T.2    Monie, A.3
  • 43
    • 0035874608 scopus 로고    scopus 로고
    • Tumor-reactive T helper lymphocytes recognize a promiscuous MAGE-A3 epitope presented by various major histocompatibility complex class II alleles
    • 1:CAS:528:DC%2BD3MXks1Grtbc%3D 11406551
    • H Kobayashi Y Song DS Hoon, et al. 2001 Tumor-reactive T helper lymphocytes recognize a promiscuous MAGE-A3 epitope presented by various major histocompatibility complex class II alleles Cancer Res 61 4773 4778 1:CAS:528:DC%2BD3MXks1Grtbc%3D 11406551
    • (2001) Cancer Res , vol.61 , pp. 4773-4778
    • Kobayashi, H.1    Song, Y.2    Hoon, D.S.3
  • 44
    • 0036793872 scopus 로고    scopus 로고
    • Identification of an antigenic epitope for helper T lymphocytes from carcinoembryonic antigen
    • 1:CAS:528:DC%2BD38XosFKhsbg%3D 12374692
    • H Kobayashi R Omiya M Ruiz, et al. 2002 Identification of an antigenic epitope for helper T lymphocytes from carcinoembryonic antigen Clin Cancer Res 8 3219 3225 1:CAS:528:DC%2BD38XosFKhsbg%3D 12374692
    • (2002) Clin Cancer Res , vol.8 , pp. 3219-3225
    • Kobayashi, H.1    Omiya, R.2    Ruiz, M.3
  • 46
    • 0035377009 scopus 로고    scopus 로고
    • Antigen decoding by T lymphocytes: From synapses to fate determination
    • DOI 10.1038/88678
    • A Lanzavecchia F Sallusto 2001 Antigen decoding by T lymphocytes: from synapses to fate determination Nat Immunol 2 487 492 10.1038/88678 1:CAS:528:DC%2BD3MXkt1yksrs%3D 11376334 (Pubitemid 33705849)
    • (2001) Nature Immunology , vol.2 , Issue.6 , pp. 487-492
    • Lanzavecchia, A.1    Sallusto, F.2
  • 48
    • 70449534963 scopus 로고    scopus 로고
    • Proximal glycans outside of the epitopes regulate the presentation of HIV-1 envelope gp120 helper epitopes
    • 10.4049/jimmunol.0804287 1:CAS:528:DC%2BD1MXltlymsrk%3D 19414790
    • H Li CF Xu S Blais, et al. 2009 Proximal glycans outside of the epitopes regulate the presentation of HIV-1 envelope gp120 helper epitopes J Immunol 182 6369 6378 10.4049/jimmunol.0804287 1:CAS:528:DC%2BD1MXltlymsrk%3D 19414790
    • (2009) J Immunol , vol.182 , pp. 6369-6378
    • Li, H.1    Xu, C.F.2    Blais, S.3
  • 49
    • 57649174707 scopus 로고    scopus 로고
    • Evaluation of MHC-II peptide binding prediction servers: Applications for vaccine research
    • 10.1186/1471-2105-9-S12-S22 19091022
    • HH Lin GL Zhang S Tongchusak, et al. 2008 Evaluation of MHC-II peptide binding prediction servers: applications for vaccine research BMC Bioinformatics 9 suppl 12 S22 10.1186/1471-2105-9-S12-S22 19091022
    • (2008) BMC Bioinformatics , vol.9 , Issue.SUPPL 12 , pp. 22
    • Lin, H.H.1    Zhang, G.L.2    Tongchusak, S.3
  • 50
    • 72449142802 scopus 로고    scopus 로고
    • Unravelling the mechanisms of help for CD8+ T cell responses
    • Livingstone AM, Wilson EB, Ontiveros F, Wang JC (2009) Unravelling the mechanisms of help for CD8+ T cell responses. Immunol Res 45(2-3):209-217
    • (2009) Immunol Res , vol.45 , Issue.2-3 , pp. 209-217
    • Livingstone, A.M.1    Wilson, E.B.2    Ontiveros, F.3    Wang, J.C.4
  • 51
    • 1642504308 scopus 로고    scopus 로고
    • MHC Class II tetramers and the pursuit of antigen-specific T cells: Define, deviate, delete
    • DOI 10.1016/j.clim.2003.11.004, PII S1521661603003115
    • R Mallone GT Nepom 2004 MHC Class II tetramers and the pursuit of antigen-specific T cells: define, deviate, delete Clin Immunol 110 232 242 10.1016/j.clim.2003.11.004 1:CAS:528:DC%2BD2cXis1WhtL8%3D 15047201 (Pubitemid 38402003)
    • (2004) Clinical Immunology , vol.110 , Issue.3 , pp. 232-242
    • Mallone, R.1    Nepom, G.T.2
  • 52
    • 0035392964 scopus 로고    scopus 로고
    • Identification of T helper epitopes from prostatic acid phosphatase
    • 1:CAS:528:DC%2BD3MXltVCjsrw%3D 11431355
    • DG McNeel LD Nguyen ML Disis 2001 Identification of T helper epitopes from prostatic acid phosphatase Cancer Res 61 5161 5167 1:CAS:528: DC%2BD3MXltVCjsrw%3D 11431355
    • (2001) Cancer Res , vol.61 , pp. 5161-5167
    • McNeel, D.G.1    Nguyen, L.D.2    Disis, M.L.3
  • 53
    • 34548779833 scopus 로고    scopus 로고
    • Human cytotoxic CD4+ T cells recognize HLA-DR1-restricted epitopes on vaccinia virus proteins A24R and D1R conserved among poxviruses
    • 1:CAS:528:DC%2BD2sXnt1Wntb0%3D 17617623
    • S Mitra-Kaushik J Cruz LJ Stern, et al. 2007 Human cytotoxic CD4+ T cells recognize HLA-DR1-restricted epitopes on vaccinia virus proteins A24R and D1R conserved among poxviruses J Immunol 179 1303 1312 1:CAS:528: DC%2BD2sXnt1Wntb0%3D 17617623
    • (2007) J Immunol , vol.179 , pp. 1303-1312
    • Mitra-Kaushik, S.1    Cruz, J.2    Stern, L.J.3
  • 54
    • 33746179157 scopus 로고    scopus 로고
    • Putting immunoinformatics to the test
    • DOI 10.1038/nbt0706-791, PII NBT0706791
    • L Moise AS De Groot 2006 Putting immunoinformatics to the test Nat Biotechnol 24 791 792 10.1038/nbt0706-791 1:CAS:528:DC%2BD28XmvFagu7o%3D 16841062 (Pubitemid 44086616)
    • (2006) Nature Biotechnology , vol.24 , Issue.7 , pp. 791-792
    • Moise, L.1    De Groot, A.S.2
  • 56
    • 60349097841 scopus 로고    scopus 로고
    • Th1 cell reactivity and HLA-DR binding prediction for promiscuous recognition of MPT63 (Rv1926c), a major secreted protein of Mycobacterium tuberculosis
    • 10.1111/j.1365-3083.2008.02221.x 1:CAS:528:DC%2BD1MXjvFOrtLk%3D 19281533
    • AS Mustafa 2009 Th1 cell reactivity and HLA-DR binding prediction for promiscuous recognition of MPT63 (Rv1926c), a major secreted protein of Mycobacterium tuberculosis Scand J Immunol 69 213 222 10.1111/j.1365-3083.2008. 02221.x 1:CAS:528:DC%2BD1MXjvFOrtLk%3D 19281533
    • (2009) Scand J Immunol , vol.69 , pp. 213-222
    • Mustafa, A.S.1
  • 57
    • 48249083459 scopus 로고    scopus 로고
    • Quantitative predictions of peptide binding to any HLA-DR molecule of known sequence: NetMHCIIpan
    • 10.1371/journal.pcbi.1000107 18604266
    • M Nielsen C Lundegaard T Blicher, et al. 2008 Quantitative predictions of peptide binding to any HLA-DR molecule of known sequence: NetMHCIIpan PLoS Comput Biol 4 e1000107 10.1371/journal.pcbi.1000107 18604266
    • (2008) PLoS Comput Biol , vol.4 , pp. 1000107
    • Nielsen, M.1    Lundegaard, C.2    Blicher, T.3
  • 58
    • 40049101044 scopus 로고    scopus 로고
    • CD4 T cells are required for CD8 T cell survival during both primary and memory recall responses
    • 1:CAS:528:DC%2BD2sXhtlyitrfE 18056368
    • P Novy M Quigley X Huang, et al. 2007 CD4 T cells are required for CD8 T cell survival during both primary and memory recall responses J Immunol 179 8243 8251 1:CAS:528:DC%2BD2sXhtlyitrfE 18056368
    • (2007) J Immunol , vol.179 , pp. 8243-8251
    • Novy, P.1    Quigley, M.2    Huang, X.3
  • 59
    • 63949087382 scopus 로고    scopus 로고
    • Identification of novel helper epitopes of MAGE-A4 tumour antigen: Useful tool for the propagation of Th1 cells
    • 10.1038/sj.bjc.6604966 1:CAS:528:DC%2BD1MXktVGktrs%3D 19277034
    • T Ohkuri D Wakita K Chamoto, et al. 2009 Identification of novel helper epitopes of MAGE-A4 tumour antigen: useful tool for the propagation of Th1 cells Br J Cancer 100 1135 1143 10.1038/sj.bjc.6604966 1:CAS:528:DC%2BD1MXktVGktrs%3D 19277034
    • (2009) Br J Cancer , vol.100 , pp. 1135-1143
    • Ohkuri, T.1    Wakita, D.2    Chamoto, K.3
  • 61
    • 0034629284 scopus 로고    scopus 로고
    • Identification of vaccine candidates against serogroup B meningococcus by whole-genome sequencing
    • DOI 10.1126/science.287.5459.1816
    • M Pizza V Scarlato V Masignani, et al. 2000 Identification of vaccine candidates against serogroup B meningococcus by whole-genome sequencing Science 287 1816 1820 10.1126/science.287.5459.1816 1:CAS:528:DC%2BD3cXhvVWksbk%3D 10710308 (Pubitemid 30143965)
    • (2000) Science , vol.287 , Issue.5459 , pp. 1816-1820
    • Rappuoli, R.1
  • 62
    • 38549105061 scopus 로고    scopus 로고
    • Predicting peptides binding to MHC class II molecules using multi-objective evolutionary algorithms
    • DOI 10.1186/1471-2105-8-459
    • M Rajapakse B Schmidt L Feng, et al. 2007 Predicting peptides binding to MHC class II molecules using multi-objective evolutionary algorithms BMC Bioinformatics 8 459 10.1186/1471-2105-8-459 18031584 (Pubitemid 351150055)
    • (2007) BMC Bioinformatics , vol.8 , pp. 459
    • Rajapakse, M.1    Schmidt, B.2    Feng, L.3    Brusic, V.4
  • 63
    • 65349181344 scopus 로고    scopus 로고
    • CD4+ T cells are required for the priming of CD8+ T cells following infection with herpes simplex virus type 1
    • 10.1128/JVI.01997-08 1:CAS:528:DC%2BD1MXlvVGhtbg%3D 19279095
    • NK Rajasagi SH Kassim CM Kollias, et al. 2009 CD4+ T cells are required for the priming of CD8+ T cells following infection with herpes simplex virus type 1 J Virol 83 5256 5268 10.1128/JVI.01997-08 1:CAS:528:DC%2BD1MXlvVGhtbg%3D 19279095
    • (2009) J Virol , vol.83 , pp. 5256-5268
    • Rajasagi, N.K.1    Kassim, S.H.2    Kollias, C.M.3
  • 64
    • 0033388725 scopus 로고    scopus 로고
    • SYFPEITHI: Database for MHC ligands and peptide motifs
    • 10.1007/s002510050595 1:CAS:528:DyaK1MXntlalsbs%3D 10602881
    • H Rammensee J Bachmann NP Emmerich, et al. 1999 SYFPEITHI: database for MHC ligands and peptide motifs Immunogenetics 50 213 219 10.1007/s002510050595 1:CAS:528:DyaK1MXntlalsbs%3D 10602881
    • (1999) Immunogenetics , vol.50 , pp. 213-219
    • Rammensee, H.1    Bachmann, J.2    Emmerich, N.P.3
  • 65
    • 0033787577 scopus 로고    scopus 로고
    • Reverse vaccinology
    • 10.1016/S1369-5274(00)00119-3 1:CAS:528:DC%2BD3cXotVOit70%3D 11050440
    • R Rappuoli 2000 Reverse vaccinology Curr Opin Microbiol 3 445 450 10.1016/S1369-5274(00)00119-3 1:CAS:528:DC%2BD3cXotVOit70%3D 11050440
    • (2000) Curr Opin Microbiol , vol.3 , pp. 445-450
    • Rappuoli, R.1
  • 66
    • 0036727207 scopus 로고    scopus 로고
    • Prediction of MHC class I binding peptides using profile motifs
    • DOI 10.1016/S0198-8859(02)00432-9, PII S0198885902004329
    • PA Reche JP Glutting EL Reinherz 2002 Prediction of MHC class I binding peptides using profile motifs Hum Immunol 63 701 709 10.1016/S0198-8859(02) 00432-9 1:CAS:528:DC%2BD38XmtVWnsLs%3D 12175724 (Pubitemid 34983301)
    • (2002) Human Immunology , vol.63 , Issue.9 , pp. 701-709
    • Reche, P.A.1    Glutting, J.-P.2    Reinherz, E.L.3
  • 67
    • 0032482337 scopus 로고    scopus 로고
    • + T- helper and a T-killer cell
    • DOI 10.1038/30989
    • JP Ridge F Di Rosa P Matzinger 1998 A conditioned dendritic cell can be a temporal bridge between a CD4+ T-helper and a T-killer cell Nature 393 474 478 10.1038/30989 1:CAS:528:DyaK1cXjs1Kms7s%3D 9624003 (Pubitemid 28292194)
    • (1998) Nature , vol.393 , Issue.6684 , pp. 474-478
    • Ridge, J.P.1    Di Rosa, F.2    Matzinger, P.3
  • 68
    • 58149196190 scopus 로고    scopus 로고
    • The IMGT/HLA database
    • 10.1093/nar/gkn662 1:CAS:528:DC%2BD1cXhsFejt7nN 18838392
    • J Robinson MJ Waller SC Fail, et al. 2009 The IMGT/HLA database Nucleic Acids Res 37 Database issue D1013 D1017 10.1093/nar/gkn662 1:CAS:528: DC%2BD1cXhsFejt7nN 18838392
    • (2009) Nucleic Acids Res , vol.37 , Issue.DATABASE ISSUE
    • Robinson, J.1    Waller, M.J.2    Fail, S.C.3
  • 69
    • 1842680774 scopus 로고    scopus 로고
    • The pan HLA DR-binding epitope improves adjuvant-assisted immunization with a recombinant protein containing a malaria vaccine candidate
    • DOI 10.1016/j.imlet.2004.01.006, PII S0165247804000070
    • DS Rosa F Tzelepis MG Cunha, et al. 2004 The pan HLA DR-binding epitope improves adjuvant-assisted immunization with a recombinant protein containing a malaria vaccine candidate Immunol Lett 92 259 268 10.1016/j.imlet.2004.01.006 1:CAS:528:DC%2BD2cXjtV2gtLk%3D 15081621 (Pubitemid 38476986)
    • (2004) Immunology Letters , vol.92 , Issue.3 , pp. 259-268
    • Rosa, D.S.1    Tzelepis, F.2    Cunha, M.G.3    Soares, I.S.4    Rodrigues, M.M.5
  • 71
    • 22544482556 scopus 로고    scopus 로고
    • The relationship between immunodominance, DM editing, and the kinetic stability of MHC class II:peptide complexes
    • DOI 10.1111/j.0105-2896.2005.00307.x
    • AJ Sant FA Chaves SA Jenks, et al. 2005 The relationship between immunodominance, DM editing, and the kinetic stability of MHC class II:peptide complexes Immunol Rev 207 261 278 10.1111/j.0105-2896.2005.00307.x 1:CAS:528:DC%2BD2MXhtFOqtL%2FL 16181342 (Pubitemid 41415023)
    • (2005) Immunological Reviews , vol.207 , pp. 261-278
    • Sant, A.J.1    Chaves, F.A.2    Jenks, S.A.3    Richards, K.A.4    Menges, P.5    Weaver, J.M.6    Lazarski, C.A.7
  • 72
    • 56349138132 scopus 로고    scopus 로고
    • Identification and evaluation of universal epitopes in Plasmodium vivax duffy binding protein
    • 10.1016/j.bbrc.2008.10.153 1:CAS:528:DC%2BD1cXhsVGhu7jP 19000655
    • C Saravia P Martinez DS Granados, et al. 2008 Identification and evaluation of universal epitopes in Plasmodium vivax duffy binding protein Biochem Biophys Res Commun 377 1279 1283 10.1016/j.bbrc.2008.10.153 1:CAS:528:DC%2BD1cXhsVGhu7jP 19000655
    • (2008) Biochem Biophys Res Commun , vol.377 , pp. 1279-1283
    • Saravia, C.1    Martinez, P.2    Granados, D.S.3
  • 73
    • 0032482474 scopus 로고    scopus 로고
    • T-cell help for cytotoxic T-lymphocytes is mediated by CD40-CD40L interactions
    • DOI 10.1038/31002
    • SP Schoenberger RE Toes EI van der Voort, et al. 1998 T-cell help for cytotoxic T lymphocytes is mediated by CD40-CD40L interactions Nature 393 480 483 10.1038/31002 1:CAS:528:DyaK1cXjs1Kmtbw%3D 9624005 (Pubitemid 28292196)
    • (1998) Nature , vol.393 , Issue.6684 , pp. 480-483
    • Schoenberger, S.P.1    Toes, R.E.M.2    Van Der Voort, E.I.H.3    Offringa, R.4    Melief, C.J.M.5
  • 74
    • 33646569665 scopus 로고    scopus 로고
    • Post-genomic vaccine development
    • DOI 10.1016/j.febslet.2006.04.084, PII S0014579306005412
    • D Serruto R Rappuoli 2006 Post-genomic vaccine development FEBS Lett 580 2985 2992 10.1016/j.febslet.2006.04.084 1:CAS:528:DC%2BD28XltVKntb8%3D 16716781 (Pubitemid 43729171)
    • (2006) FEBS Letters , vol.580 , Issue.12 , pp. 2985-2992
    • Serruto, D.1    Rappuoli, R.2
  • 75
    • 0041402836 scopus 로고    scopus 로고
    • Epitope-based vaccines: An update on epitope identification, vaccine design and delivery
    • DOI 10.1016/S0952-7915(03)00083-9
    • A Sette J Fikes 2003 Epitope-based vaccines: an update on epitope identification, vaccine design and delivery Curr Opin Immunol 15 461 470 10.1016/S0952-7915(03)00083-9 1:CAS:528:DC%2BD3sXlvFymurY%3D 12900280 (Pubitemid 36934509)
    • (2003) Current Opinion in Immunology , vol.15 , Issue.4 , pp. 461-470
    • Sette, A.1    Fikes, J.2
  • 76
    • 0037606124 scopus 로고    scopus 로고
    • ProPred1: Prediction of promiscuous MHC class-I binding sites
    • DOI 10.1093/bioinformatics/btg108
    • H Singh GP Raghava 2003 ProPred1: prediction of promiscuous MHC Class-I binding sites Bioinformatics 19 1009 1014 10.1093/bioinformatics/btg108 1:CAS:528:DC%2BD3sXktVCgsrY%3D 12761064 (Pubitemid 36675822)
    • (2003) Bioinformatics , vol.19 , Issue.8 , pp. 1009-1014
    • Singh, H.1    Raghava, G.P.S.2
  • 78
    • 0028348369 scopus 로고
    • Crystal structure of the human class II MHC protein HLA-DR1 complexed with an influenza virus peptide
    • DOI 10.1038/368215a0
    • LJ Stern JH Brown TS Jardetzky, et al. 1994 Crystal structure of the human class II MHC protein MHC-DR1 complexed with an influenza virus peptide Nature 368 215 221 10.1038/368215a0 1:CAS:528:DyaK2cXktlaltLs%3D 8145819 (Pubitemid 24108837)
    • (1994) Nature , vol.368 , Issue.6468 , pp. 215-221
    • Stern, L.J.1    Brown, J.H.2    Jardetzky, T.S.3    Gorga, J.C.4    Urban, R.G.5    Strominger, J.L.6    Wiley, D.C.7
  • 80
    • 0037341162 scopus 로고    scopus 로고
    • MAGE-6 encodes HLA-DRbeta1 0401-presented epitopes recognized by CD4+ T cells from patients with melanoma or renal cell carcinoma
    • 1:CAS:528:DC%2BD3sXhvFKiurg%3D 12631591
    • T Tatsumi LS Kierstead E Ranieri, et al. 2003 MAGE-6 encodes HLA-DRbeta1 0401-presented epitopes recognized by CD4+ T cells from patients with melanoma or renal cell carcinoma Clin Cancer Res 9 947 954 1:CAS:528:DC%2BD3sXhvFKiurg%3D 12631591
    • (2003) Clin Cancer Res , vol.9 , pp. 947-954
    • Tatsumi, T.1    Kierstead, L.S.2    Ranieri, E.3
  • 81
    • 72449135412 scopus 로고    scopus 로고
    • An approach to the identification of T cell epitopes in the genomic era: Application to Francisella tularensis
    • Valentino M, Frelinger J (2009) An approach to the identification of T cell epitopes in the genomic era: application to Francisella tularensis. Immunol Res 45(2-3):218-228
    • (2009) Immunol Res , vol.45 , Issue.2-3 , pp. 218-228
    • Valentino, M.1    Frelinger, J.2
  • 82
    • 34548805887 scopus 로고    scopus 로고
    • A quantitative genotype algorithm reflecting H5N1 Avian influenza niches
    • DOI 10.1093/bioinformatics/btm354
    • XF Wan G Chen F Luo, et al. 2007 A quantitative genotype algorithm reflecting H5N1 Avian influenza niches Bioinformatics 23 2368 2375 10.1093/bioinformatics/btm354 1:CAS:528:DC%2BD2sXhtVOku7%2FK 17623701 (Pubitemid 47423833)
    • (2007) Bioinformatics , vol.23 , Issue.18 , pp. 2368-2375
    • Wan, X.-F.1    Chen, G.2    Luo, F.3    Emch, M.4    Donis, R.5
  • 83
    • 42949139524 scopus 로고    scopus 로고
    • A systematic assessment of MHC class II peptide binding predictions and evaluation of a consensus approach
    • DOI 10.1371/journal.pcbi.1000048
    • P Wang J Sidney C Dow, et al. 2008 A systematic assessment of MHC class II peptide binding predictions and evaluation of a consensus approach PLoS Comput Biol 4 e1000048 10.1371/journal.pcbi.1000048 18389056 (Pubitemid 351656722)
    • (2008) PLoS Computational Biology , vol.4 , Issue.4
    • Wang, P.1    Sidney, J.2    Dow, C.3    Mothe, B.4    Sette, A.5    Peters, B.6
  • 84
    • 44949100369 scopus 로고    scopus 로고
    • Nonhuman primate models and the failure of the Merck HIV-1 vaccine in humans
    • DOI 10.1038/nm.f.1759, PII NMF1759
    • DI Watkins DR Burton EG Kallas, et al. 2008 Nonhuman primate models and the failure of the Merck HIV-1 vaccine in humans Nat Med 14 617 621 10.1038/nm.f.1759 1:CAS:528:DC%2BD1cXmvVCnsbg%3D 18535579 (Pubitemid 351809543)
    • (2008) Nature Medicine , vol.14 , Issue.6 , pp. 617-621
    • Watkins, D.I.1    Burton, D.R.2    Kallas, E.G.3    Moore, J.P.4    Koff, W.C.5
  • 85
    • 0035043295 scopus 로고    scopus 로고
    • Identification and antigenicity of broadly cross-reactive and conserved human immunodeficiency virus type 1-derived helper T-lymphocyte epitopes
    • DOI 10.1128/JVI.75.9.4195-4207.2001
    • CC Wilson B Palmer S Southwood, et al. 2001 Identification and antigenicity of broadly cross-reactive and conserved human immunodeficiency virus type 1-derived helper T-lymphocyte epitopes J Virol 75 4195 4207 10.1128/JVI.75.9.4195-4207.2001 1:CAS:528:DC%2BD3MXivFOkt7s%3D 11287569 (Pubitemid 32410132)
    • (2001) Journal of Virology , vol.75 , Issue.9 , pp. 4195-4207
    • Wilson, C.C.1    Palmer, B.2    Southwood, S.3    Sidney, J.4    Higashimoto, Y.5    Appella, E.6    Chesnut, R.7    Sette, A.8    Livingston, B.D.9
  • 86
    • 0035928858 scopus 로고    scopus 로고
    • The role of t cell help for anti-viral CTL responses
    • DOI 10.1006/jtbi.2001.2358
    • D Wodarz VA Jansen 2001 The role of T cell help for anti-viral CTL responses J Theor Biol 211 419 432 10.1006/jtbi.2001.2358 1:CAS:528: DC%2BD3MXlsVWgur4%3D 11476625 (Pubitemid 32730529)
    • (2001) Journal of Theoretical Biology , vol.211 , Issue.4 , pp. 419-432
    • Wodarz, D.1    Jansen, V.A.A.2
  • 88
    • 64049090391 scopus 로고    scopus 로고
    • An introduction to epitope prediction methods and software
    • 10.1002/rmv.602 1:CAS:528:DC%2BD1MXkt1eltr8%3D 19101924
    • X Yang X Yu 2009 An introduction to epitope prediction methods and software Rev Med Virol 19 77 96 10.1002/rmv.602 1:CAS:528:DC%2BD1MXkt1eltr8%3D 19101924
    • (2009) Rev Med Virol , vol.19 , pp. 77-96
    • Yang, X.1    Yu, X.2
  • 89
    • 22144458334 scopus 로고    scopus 로고
    • d molecules, a haplotype of the BALB/c mouse
    • DOI 10.1093/nar/gki479
    • GL Zhang KN Srinivasan A Veeramani, et al. 2005 PREDBALB/c: a system for the prediction of peptide binding to H2d molecules, a haplotype of the BALB/c mouse Nucleic Acids Res 33 Web Server issue W180 W183 10.1093/nar/gki479 1:CAS:528:DC%2BD2MXlslyqtbw%3D 15980450 (Pubitemid 44529904)
    • (2005) Nucleic Acids Research , vol.33 , Issue.WEB. SERV. ISS.
    • Zhang, G.L.1    Srinivasan, K.N.2    Veeraman, A.3    August, J.T.4    Brusic, V.5
  • 90
    • 28044452174 scopus 로고    scopus 로고
    • Neural models for predicting viral vaccine targets
    • 10.1142/S0219720005001466
    • GL Zhang AM Khan KN Srinivasan, et al. 2007 Neural models for predicting viral vaccine targets J Bioinform Comput Biol 3 1207 1225 10.1142/ S0219720005001466
    • (2007) J Bioinform Comput Biol , vol.3 , pp. 1207-1225
    • Zhang, G.L.1    Khan, A.M.2    Srinivasan, K.N.3
  • 91
    • 65649117727 scopus 로고    scopus 로고
    • The role of CD4 T cell help for CD8 CTL activation
    • 10.1016/j.bbrc.2009.04.134 1:CAS:528:DC%2BD1MXmsVCgsLc%3D 19410556
    • S Zhang H Zhang J Zhao 2009 The role of CD4 T cell help for CD8 CTL activation Biochem Biophys Res Commun 384 405 408 10.1016/j.bbrc.2009.04.134 1:CAS:528:DC%2BD1MXmsVCgsLc%3D 19410556
    • (2009) Biochem Biophys Res Commun , vol.384 , pp. 405-408
    • Zhang, S.1    Zhang, H.2    Zhao, J.3


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