Stability of lyophilized siRNA nanosome formulations

International Journal of Pharmaceutics

Volumn 423, Issue 2, 2012, Pages 525-534

  Kundu, Anup K ^a   Chandra, Partha K ^b   Hazari, Sidhartha ^b   Ledet, Grace ^a   Pramar, Yashoda V ^a   Dash, Srikanta ^b   Mandal, Tarun K ^a  

^a XAVIER UNIVERSITY OF LOUISIANA   (United States)

^b TULANE UNIVERSITY HEALTH SCIENCES CENTER   (United States)

Author keywords

Hepatitis C virus; Lyophilization; Nanosome; siRNA delivery; Stability

Indexed keywords

ALPHA INTERFERON; LIPOSOME; NANOPARTICLE; SMALL INTERFERING RNA;

ARTICLE; CELL CULTURE; CELL VIABILITY; CONTROLLED STUDY; DRUG FORMULATION; DRUG STABILITY; DRUG STORAGE; FREEZE DRYING; GENE SILENCING; HEPATITIS C VIRUS; HUMAN; IN VITRO STUDY; NANOENCAPSULATION; NONHUMAN; PARTICLE SIZE; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; RNA SEQUENCE; RNA STABILITY; ZETA POTENTIAL;

ANTIVIRAL AGENTS; CELL LINE, TUMOR; DRUG RESISTANCE, VIRAL; FREEZE DRYING; GENE THERAPY; HEPACIVIRUS; HUMANS; INTERFERON-ALPHA; LIPIDS; LIPOSOMES; NANOPARTICLES; NANOTECHNOLOGY; NUCLEIC ACID CONFORMATION; PARTICLE SIZE; PROTAMINES; RNA INTERFERENCE; RNA STABILITY; RNA, SMALL INTERFERING; TIME FACTORS; TRANSFECTION; VIRUS REPLICATION;

EID: 84856558643     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2011.11.040     Document Type: Article

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