Prediction of the appropriate size of drug molecules that could be released by a pulsatile mechanism from pH/thermoresponsive microspheres obtained from preformed polymers

Acta Biomaterialia

Volumn 8, Issue 3, 2012, Pages 1281-1289

  Fundueanu, Gheorghe ^a,b   Constantin, Marieta ^a   Oanea, Ionela ^a   Harabagiu, Valeria ^a   Ascenzi, Paolo ^c   Simionescu, Bogdan C ^a,d  

^a PETRU PONI INSTITUTE OF MACROMOLECULAR CHEMISTRY   (Romania)

^b UNIVERSITY OF FERRARA   (Italy)

^c ROMA TRE UNIVERSITY   (Italy)

^d GHEORGHE ASACHI TECHNICAL UNIVERSITY OF IASI   (Romania)

Author keywords

Drug delivery system; Inverse size exclusion chromatography; Lower critical solution temperature; pH thermoresponsive copolymers; Smart polymers

Indexed keywords

ACRYLIC MONOMERS; BENZOIC ACID; CHROMATOGRAPHIC ANALYSIS; CROSSLINKING; INVERSE PROBLEMS; MOLECULAR WEIGHT; MOLECULES; SALICYLIC ACID; SIZE EXCLUSION CHROMATOGRAPHY; TARGETED DRUG DELIVERY;

CRITICAL SOLUTION TEMPERATURE; DRUG-DELIVERY SYSTEMS; INVERSE SIZE EXCLUSION CHROMATOGRAPHY; LOW CRITICAL SOLUTION TEMPERATURE; LOWER CRITICAL; PH/THERMORESPONSIVE COPOLYMER; PULSATILES; SMART POLYMERS; THERMO-RESPONSIVE COPOLYMERS; THERMO-RESPONSIVE MICROSPHERES;

CONTROLLED DRUG DELIVERY;

BENZOIC ACID; BOVINE SERUM ALBUMIN; DICLOFENAC; HEPARIN; LIDOCAINE; LYSOZYME; MICROSPHERE; N ALLOC ETHYLENEDIAMINE; N ISOPROPYLACRYLAMIDE; NICOTINIC ACID; POLYMER; SALICYLIC ACID; UNCLASSIFIED DRUG;

ARTICLE; DRUG RELEASE; MOLECULAR SIZE; MOLECULAR WEIGHT; PH; PHASE TRANSITION; PRIORITY JOURNAL; TEMPERATURE;

BOVINAE;

EID: 84856555129     PISSN: 17427061     EISSN: 18787568     Source Type: Journal    
DOI: 10.1016/j.actbio.2011.09.007     Document Type: Article

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