메뉴 건너뛰기




Volumn 7, Issue 4, 2011, Pages 1460-1467

Thermoresponsive, in situ cross-linkable hydrogels based on N-isopropylacrylamide: Fabrication, characterization and mesenchymal stem cell encapsulation

Author keywords

Cell encapsulation; Covalent cross linking; Hydrogel; N isopropylacrylamide; Thermoresponsive

Indexed keywords

ACRYLIC MONOMERS; AMIDES; CELL CULTURE; CELL ENGINEERING; CROSSLINKING; FABRICATION; PHASE SEPARATION; STEM CELLS; SWELLING; TISSUE ENGINEERING;

EID: 79952189109     PISSN: 17427061     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.actbio.2010.12.027     Document Type: Article
Times cited : (66)

References (38)
  • 1
    • 0037122786 scopus 로고    scopus 로고
    • Thermosensitive sol-gel reversible hydrogels
    • DOI 10.1016/S0169-409X(01)00242-3, PII S0169409X01002423
    • B. Jeong, S.W. Kim, and Y.H. Bae Thermosensitive sol-gel reversible hydrogels Adv Drug Delivery Rev 54 2002 37 51 (Pubitemid 34075313)
    • (2002) Advanced Drug Delivery Reviews , vol.54 , Issue.1 , pp. 37-51
    • Jeong, B.1    Kim, S.W.2    Bae, Y.H.3
  • 2
    • 36549073613 scopus 로고    scopus 로고
    • Thermoresponsive hydrogels in biomedical applications
    • DOI 10.1016/j.ejpb.2007.02.025, PII S0939641107002470, Interactive Polymers for Pharmaceutical and Biomedical Applications
    • L. Klouda, and A.G. Mikos Thermoresponsive hydrogels in biomedical applications Eur J Pharm Biopharm 68 2008 34 45 (Pubitemid 350181413)
    • (2008) European Journal of Pharmaceutics and Biopharmaceutics , vol.68 , Issue.1 , pp. 34-45
    • Klouda, L.1    Mikos, A.G.2
  • 4
    • 73449086675 scopus 로고    scopus 로고
    • PH- and temperature-sensitive polymeric microspheres for drug delivery: The dissolution of copolymers modulates drug release
    • G. Fundueanu, M. Constantin, C. Stanciu, G. Theodoridis, and P. Ascenzi PH- and temperature-sensitive polymeric microspheres for drug delivery: the dissolution of copolymers modulates drug release J Mater Sci 20 2009 2465 2475
    • (2009) J Mater Sci , vol.20 , pp. 2465-2475
    • Fundueanu, G.1    Constantin, M.2    Stanciu, C.3    Theodoridis, G.4    Ascenzi, P.5
  • 5
    • 70349290518 scopus 로고    scopus 로고
    • Subconjunctivally implantable hydrogels with degradable and thermoresponsive properties for sustained release of insulin to the retina
    • G.P. Misra, R.S. Singh, T.S. Aleman, S.G. Jacobson, T.W. Gardner, and T.L. Lowe Subconjunctivally implantable hydrogels with degradable and thermoresponsive properties for sustained release of insulin to the retina Biomaterials 30 2009 6541 6547
    • (2009) Biomaterials , vol.30 , pp. 6541-6547
    • Misra, G.P.1    Singh, R.S.2    Aleman, T.S.3    Jacobson, S.G.4    Gardner, T.W.5    Lowe, T.L.6
  • 6
    • 77955278409 scopus 로고    scopus 로고
    • Comb-type grafted poly(N-isopropylacrylamide) gel modified surfaces for rapid detachment of cell sheet
    • Z. Tang, Y. Akiyama, M. Yamato, and T. Okano Comb-type grafted poly(N-isopropylacrylamide) gel modified surfaces for rapid detachment of cell sheet Biomaterials 31 2010 7435 7443
    • (2010) Biomaterials , vol.31 , pp. 7435-7443
    • Tang, Z.1    Akiyama, Y.2    Yamato, M.3    Okano, T.4
  • 7
    • 77953266516 scopus 로고    scopus 로고
    • Design of a self-cleaning thermoresponsive nanocomposite hydrogel membrane for implantable biosensors
    • R.M. Gant, A.A. Abraham, Y. Hou, B.M. Cummins, M.A. Grunlan, and G.L. Cote Design of a self-cleaning thermoresponsive nanocomposite hydrogel membrane for implantable biosensors Acta Biomater 6 2010 2903 2910
    • (2010) Acta Biomater , vol.6 , pp. 2903-2910
    • Gant, R.M.1    Abraham, A.A.2    Hou, Y.3    Cummins, B.M.4    Grunlan, M.A.5    Cote, G.L.6
  • 8
    • 67650383437 scopus 로고    scopus 로고
    • Synthesis, characterization and therapeutic efficacy of a biodegradable, thermoresponsive hydrogel designed for application in chronic infarcted myocardium
    • K.L. Fujimoto, Z. Ma, D.M. Nelson, R. Hashizume, J. Guan, and K. Tobita Synthesis, characterization and therapeutic efficacy of a biodegradable, thermoresponsive hydrogel designed for application in chronic infarcted myocardium Biomaterials 30 2009 4357 4368
    • (2009) Biomaterials , vol.30 , pp. 4357-4368
    • Fujimoto, K.L.1    Ma, Z.2    Nelson, D.M.3    Hashizume, R.4    Guan, J.5    Tobita, K.6
  • 9
    • 43149085742 scopus 로고    scopus 로고
    • Protein-reactive, thermoresponsive copolymers with high flexibility and biodegradability
    • DOI 10.1021/bm701265j
    • J. Guan, Y. Hong, Z. Ma, and W.R. Wagner Protein-reactive, thermoresponsive copolymers with high flexibility and biodegradability Biomacromolecules 9 2008 1283 1292 (Pubitemid 351639583)
    • (2008) Biomacromolecules , vol.9 , Issue.4 , pp. 1283-1292
    • Guan, J.1    Hong, Y.2    Ma, Z.3    Wagner, W.R.4
  • 10
    • 0033517611 scopus 로고    scopus 로고
    • Synthesis and characterization of injectable poly(N-isopropylacrylamide)- based hydrogels that support tissue formation in vitro
    • DOI 10.1021/ma990130w
    • R.A. Stile, W.R. Burghardt, and K.E. Healy Synthesis and characterization of injectable poly(N-isopropylacrylamide)-based hydrogels that support tissue formation in vitro Macromolecules 32 1999 7370 7379 (Pubitemid 30537680)
    • (1999) Macromolecules , vol.32 , Issue.22 , pp. 7370-7379
    • Stile, R.A.1    Burghardt, W.R.2    Healy, K.E.3
  • 12
    • 0004991063 scopus 로고
    • Poly(N-isopropylacrylamide): Experiment, theory and application
    • H.G. Schild Poly(N-isopropylacrylamide): experiment, theory and application Prog Polym Sci 17 1992 163 249
    • (1992) Prog Polym Sci , vol.17 , pp. 163-249
    • Schild, H.G.1
  • 13
    • 77955778221 scopus 로고    scopus 로고
    • In situ forming hydrogels by tandem thermal gelling and Michael addition reaction between thermosensitive triblock copolymers and thiolated hyaluronan
    • R. Censi, P.J. Fieten, P. di Martino, W.E. Hennink, and T. Vermonden In situ forming hydrogels by tandem thermal gelling and Michael addition reaction between thermosensitive triblock copolymers and thiolated hyaluronan Macromolecules 43 2010 5771 5778
    • (2010) Macromolecules , vol.43 , pp. 5771-5778
    • Censi, R.1    Fieten, P.J.2    Di Martino, P.3    Hennink, W.E.4    Vermonden, T.5
  • 14
    • 34548535410 scopus 로고    scopus 로고
    • Poly(N-isopropylacrylamide-co-poly(ethylene glycol))-acrylate simultaneously physically and chemically gelling polymer systems
    • DOI 10.1002/app.26760
    • V. Cheng, B.H. Lee, C. Pauken, and B.L. Vernon Poly(N- isopropylacrylamide-co-poly(ethylene glycol))-acrylate simultaneously physically and chemically gelling polymer systems J Appl Polym Sci 106 2007 1201 1207 (Pubitemid 47384101)
    • (2007) Journal of Applied Polymer Science , vol.106 , Issue.2 , pp. 1201-1207
    • Cheng, V.1    Lee, B.H.2    Pauken, C.3    Vernon, B.L.4
  • 15
    • 33745610186 scopus 로고    scopus 로고
    • In-situ injectable physically and chemically gelling NIPAAm-based copolymer system for embolization
    • DOI 10.1021/bm060211h
    • B.H. Lee, B. West, R. McLemore, C. Pauken, and B.L. Vernon In-situ injectable physically and chemically gelling NIPAAm-based copolymer system for embolization Biomacromolecules 7 2006 2059 2064 (Pubitemid 43985133)
    • (2006) Biomacromolecules , vol.7 , Issue.6 , pp. 2059-2064
    • Lee, B.H.1    West, B.2    McLemore, R.3    Pauken, C.4    Vernon, B.L.5
  • 16
    • 34547129075 scopus 로고    scopus 로고
    • Simultaneously physically and chemically gelling polymer system utilizing a poly(NIPAAm-co-cysteamine)-based copolymer
    • DOI 10.1021/bm070267r
    • S.A. Robb, B.H. Lee, R. McLemore, and B.L. Vernon Simultaneously physically and chemically gelling polymer system utilizing a poly(NIPAAm-co-cysteamine)-based copolymer Biomacromolecules 8 2007 2294 2300 (Pubitemid 47104317)
    • (2007) Biomacromolecules , vol.8 , Issue.7 , pp. 2294-2300
    • Robb, S.A.1    Lee, B.H.2    McLemore, R.3    Vernon, B.L.4
  • 17
    • 46849118467 scopus 로고    scopus 로고
    • Synthesis and characterization of injectable, thermally and chemically gelable, amphiphilic poly(N-isopropylacrylamide)-based macromers
    • DOI 10.1021/bm8000414
    • M.C. Hacker, L. Klouda, B.B. Ma, J.D. Kretlow, and A.G. Mikos Synthesis and characterization of injectable, thermally and chemically gelable, amphiphilic poly(N-isopropylacrylamide)-based macromers Biomacromolecules 9 2008 1558 1570 (Pubitemid 351954429)
    • (2008) Biomacromolecules , vol.9 , Issue.6 , pp. 1558-1570
    • Hacker, M.C.1    Klouda, L.2    Ma, B.B.3    Kretlow, J.D.4    Mikos, A.G.5
  • 18
    • 67749137593 scopus 로고    scopus 로고
    • Cytocompatibility evaluation of amphiphilic, thermally responsive and chemically crosslinkable macromers for in situ forming hydrogels
    • L. Klouda, M.C. Hacker, J.D. Kretlow, and A.G. Mikos Cytocompatibility evaluation of amphiphilic, thermally responsive and chemically crosslinkable macromers for in situ forming hydrogels Biomaterials 30 2009 4558 4566
    • (2009) Biomaterials , vol.30 , pp. 4558-4566
    • Klouda, L.1    Hacker, M.C.2    Kretlow, J.D.3    Mikos, A.G.4
  • 19
    • 77049094746 scopus 로고    scopus 로고
    • Osteogenic differentiation of mesenchymal stem cells on pregenerated extracellular matrix scaffolds in the absence of osteogenic cell culture supplements
    • R.A. Thibault, L. Scott Baggett, A.G. Mikos, and F.K. Kasper Osteogenic differentiation of mesenchymal stem cells on pregenerated extracellular matrix scaffolds in the absence of osteogenic cell culture supplements Tissue Eng 16 2010 431 440
    • (2010) Tissue Eng , vol.16 , pp. 431-440
    • Thibault, R.A.1    Scott Baggett, L.2    Mikos, A.G.3    Kasper, F.K.4
  • 20
    • 61849142793 scopus 로고    scopus 로고
    • In vitro generation of an osteochondral construct using injectable hydrogel composites encapsulating rabbit marrow mesenchymal stem cells
    • X. Guo In vitro generation of an osteochondral construct using injectable hydrogel composites encapsulating rabbit marrow mesenchymal stem cells Biomaterials 30 2009 2741 2752
    • (2009) Biomaterials , vol.30 , pp. 2741-2752
    • Guo, X.1
  • 21
    • 77955885763 scopus 로고    scopus 로고
    • Modulation of osteogenic properties of biodegradable polymer/ extracellular matrix scaffolds generated with a flow perfusion bioreactor
    • J. Liao, X. Guo, D. Nelson, F.K. Kasper, and A.G. Mikos Modulation of osteogenic properties of biodegradable polymer/extracellular matrix scaffolds generated with a flow perfusion bioreactor Acta Biomater 6 2010 2386 2393
    • (2010) Acta Biomater , vol.6 , pp. 2386-2393
    • Liao, J.1    Guo, X.2    Nelson, D.3    Kasper, F.K.4    Mikos, A.G.5
  • 22
    • 33644517215 scopus 로고    scopus 로고
    • In vitro generated extracellular matrix and fluid shear stress synergistically enhance 3D osteoblastic differentiation
    • N. Datta, Q.P. Pham, U. Sharma, V.I. Sikavitsas, J.A. Jansen, and A.G. Mikos In vitro generated extracellular matrix and fluid shear stress synergistically enhance 3D osteoblastic differentiation Proc Natl Acad Sci USA 103 2006 2488 2493
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 2488-2493
    • Datta, N.1    Pham, Q.P.2    Sharma, U.3    Sikavitsas, V.I.4    Jansen, J.A.5    Mikos, A.G.6
  • 23
    • 32144437418 scopus 로고    scopus 로고
    • How useful is SBF in predicting in vivo bone bioactivity?
    • DOI 10.1016/j.biomaterials.2006.01.017, PII S0142961206000457
    • T. Kokubo, and H. Takadama How useful is SBF in predicting in vivo bone bioactivity? Biomaterials 27 2006 2907 2915 (Pubitemid 43208916)
    • (2006) Biomaterials , vol.27 , Issue.15 , pp. 2907-2915
    • Kokubo, T.1    Takadama, H.2
  • 24
    • 0029403702 scopus 로고
    • Synthesis and characterization of thermo- and chemomechanically responsive poly(N-isopropylacrylamide-co-methacrylic acid) hydrogels
    • C.S. Brazel, and N.A. Peppas Synthesis and characterization of thermo- and chemomechanically responsive poly(N-isopropylacrylamide-co-methacrylic acid) hydrogels Macromolecules 28 1995 8016 8020
    • (1995) Macromolecules , vol.28 , pp. 8016-8020
    • Brazel, C.S.1    Peppas, N.A.2
  • 25
    • 31544469769 scopus 로고    scopus 로고
    • PH- and temperature-responsive hydrogels from crosslinked triblock copolymers prepared via consecutive atom transfer radical polymerizations
    • F.J. Xu, E.T. Kang, and K.G. Neoh pH- and temperature-responsive hydrogels from crosslinked triblock copolymers prepared via consecutive atom transfer radical polymerizations Biomaterials 27 2006 2787 2797
    • (2006) Biomaterials , vol.27 , pp. 2787-2797
    • Xu, F.J.1    Kang, E.T.2    Neoh, K.G.3
  • 26
    • 0029267842 scopus 로고
    • Comb-type grafted hydrogels with rapid de-swelling response to temperature changes
    • R. Yoshida, K. Uchida, Y. Kaneko, K. Sakai, A. Kikuchi, and Y. Sakurai Comb-type grafted hydrogels with rapid de-swelling response to temperature changes Nature 374 1995 240 242
    • (1995) Nature , vol.374 , pp. 240-242
    • Yoshida, R.1    Uchida, K.2    Kaneko, Y.3    Sakai, K.4    Kikuchi, A.5    Sakurai, Y.6
  • 28
    • 0842345370 scopus 로고    scopus 로고
    • Thermally cross-linked oligo(poly(ethylene glycol) fumarate) hydrogels support osteogenic differentiation of encapsulated marrow stromal cells in vitro
    • DOI 10.1021/bm030067p
    • J.S. Temenoff, H. Park, E. Jabbari, D.E. Conway, T.L. Sheffield, and C.G. Ambrose Thermally cross-linked oligo(poly(ethylene glycol) fumarate) hydrogels support osteogenic differentiation of encapsulated marrow stromal cells in vitro Biomacromolecules 5 2004 5 10 (Pubitemid 38181306)
    • (2004) Biomacromolecules , vol.5 , Issue.1 , pp. 5-10
    • Temenoff, J.S.1    Park, H.2    Jabbari, E.3    Conway, D.E.4    Sheffield, T.L.5    Ambrose, C.G.6    Mikos, A.G.7
  • 30
    • 27244461231 scopus 로고    scopus 로고
    • Proliferation and osteogenic differentiation of mesenchymal stem cells cultured onto three different polymers in vitro
    • DOI 10.1007/s10439-005-5889-2
    • M. Jager, T. Feser, H. Denck, and R. Krauspe Proliferation and osteogenic differentiation of mesenchymal stem cells cultured onto three different polymers in vitro Ann Biomed Eng 33 2005 1319 1332 (Pubitemid 41521250)
    • (2005) Annals of Biomedical Engineering , vol.33 , Issue.10 , pp. 1319-1332
    • Jager, M.1    Feser, T.2    Denck, H.3    Krauspe, R.4
  • 32
    • 0016698688 scopus 로고
    • Fetal bovine serum: A multivariate standard
    • K.V. Honn, J.A. Singley, and W. Chavin Fetal bovine serum: a multivariate standard Exp Biol Med 149 1975 344 347
    • (1975) Exp Biol Med , vol.149 , pp. 344-347
    • Honn, K.V.1    Singley, J.A.2    Chavin, W.3
  • 33
    • 57349151568 scopus 로고    scopus 로고
    • Cell culture systems for studies of bone and tooth mineralization
    • A.L. Boskey, and R. Roy Cell culture systems for studies of bone and tooth mineralization Chem Rev 108 2008 4716 4733
    • (2008) Chem Rev , vol.108 , pp. 4716-4733
    • Boskey, A.L.1    Roy, R.2
  • 34
    • 41749089807 scopus 로고    scopus 로고
    • Calcium oxalate crystals in fetal bovine serum: Implications for cell culture, phagocytosis and biomineralization studies in vitro
    • DOI 10.1002/jcb.21515
    • C.E. Pedraza, Y.C. Chien, and M.D. McKee Calcium oxalate crystals in fetal bovine serum: implications for cell culture, phagocytosis and biomineralization studies in vitro J Cell Biochem 103 2008 1379 1393 (Pubitemid 351490708)
    • (2008) Journal of Cellular Biochemistry , vol.103 , Issue.5 , pp. 1379-1393
    • Pedraza, C.E.1    Chien, Y.-C.2    McKee, M.D.3
  • 35
    • 33646461569 scopus 로고    scopus 로고
    • The elastic lamellae of devitalized arteries calcify when incubated in serum: Evidence for a serum calcification factor
    • DOI 10.1161/01.ATV.0000216406.44762.7c, PII 0004360520060500000021
    • P.A. Price, W.S. Chan, D.M. Jolson, and M.K. Williamson The elastic lamellae of devitalized arteries calcify when incubated in serum: evidence for a serum calcification factor Arterioscler Thromb Vasc Biol 26 2006 1079 1085 (Pubitemid 43732115)
    • (2006) Arteriosclerosis, Thrombosis, and Vascular Biology , vol.26 , Issue.5 , pp. 1079-1085
    • Price, P.A.1    Wai, S.C.2    Jolson, D.M.3    Williamson, M.K.4
  • 36
    • 2442477536 scopus 로고    scopus 로고
    • Evidence for a Serum Factor That Initiates the Re-calcification of Demineralized Bone
    • DOI 10.1074/jbc.M307880200
    • P.A. Price, H.H. June, N.J. Hamlin, and M.K. Williamson Evidence for a serum factor that initiates the re-calcification of demineralized bone J Biol Chem 279 2004 19169 19180 (Pubitemid 38623348)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.18 , pp. 19169-19180
    • Price, P.A.1    June, H.H.2    Hamlin, N.J.3    Williamson, M.K.4
  • 37
    • 4944260157 scopus 로고    scopus 로고
    • Mineralization of decalcified bone occurs under cell culture conditions and requires bovine serum but not cells
    • DOI 10.1007/s00223-004-0190-1
    • N.J. Hamlin, and P.A. Price Mineralization of decalcified bone occurs under cell culture conditions and requires bovine serum but not cells Calcif Tissue Int 75 2004 231 242 (Pubitemid 39331652)
    • (2004) Calcified Tissue International , vol.75 , Issue.3 , pp. 231-242
    • Hamlin, N.J.1    Price, P.A.2
  • 38
    • 0025597854 scopus 로고
    • Calcium and orthophosphate deposits in vitro do not imply osteoblast-mediated mineralization: Mineralization by betaglycerophosphate in the absence of osteoblasts
    • H.I. Khouja, A. Bevington, G.J. Kemp, and R.G. Russell Calcium and orthophosphate deposits in vitro do not imply osteoblast-mediated mineralization: mineralization by betaglycerophosphate in the absence of osteoblasts Bone 11 1990 385 391
    • (1990) Bone , vol.11 , pp. 385-391
    • Khouja, H.I.1    Bevington, A.2    Kemp, G.J.3    Russell, R.G.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.