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Volumn 6, Issue 4, 2010, Pages 1297-1306

Micro-structured smart hydrogels with enhanced protein loading and release efficiency

Author keywords

Drug delivery; Hydrogels; Porous materials; Responsive polymers

Indexed keywords

ACRYLIC MONOMERS; BODY FLUIDS; CONTROLLED DRUG DELIVERY; EFFICIENCY; ENZYMES; GENE TRANSFER; HYDROGELS; MICROCHANNELS; MICROSTRUCTURE; POLYDIMETHYLSILOXANE; POROSITY; SILICONES; SODIUM DODECYL SULFATE; SULFUR COMPOUNDS; SWELLING; TARGETED DRUG DELIVERY;

EID: 76949100649     PISSN: 17427061     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.actbio.2009.11.005     Document Type: Article
Times cited : (52)

References (44)
  • 2
    • 24944437204 scopus 로고    scopus 로고
    • Poly(N-isopropylacrylamide) nanoparticle-incorporated PNIPAAm hydrogels with fast shrinking kinetics
    • Zhang J.T., Huang S.W., Xue Y.N., and Zhuo R.X. Poly(N-isopropylacrylamide) nanoparticle-incorporated PNIPAAm hydrogels with fast shrinking kinetics. Macromol Rapid Commun 26 (2005) 1346-1351
    • (2005) Macromol Rapid Commun , vol.26 , pp. 1346-1351
    • Zhang, J.T.1    Huang, S.W.2    Xue, Y.N.3    Zhuo, R.X.4
  • 3
    • 12044255391 scopus 로고
    • Volume phase transition and released phenomena of polymer gels
    • Shibayama M., and Tanaka T. Volume phase transition and released phenomena of polymer gels. Adv Polym Sci 109 (1993) 1-62
    • (1993) Adv Polym Sci , vol.109 , pp. 1-62
    • Shibayama, M.1    Tanaka, T.2
  • 4
    • 0004991063 scopus 로고
    • Poly(N-isopropylacrylamide): experiment, theory and application
    • Schild H.G. Poly(N-isopropylacrylamide): experiment, theory and application. Prog Polym Sci 17 (1992) 163-249
    • (1992) Prog Polym Sci , vol.17 , pp. 163-249
    • Schild, H.G.1
  • 5
    • 34547608403 scopus 로고    scopus 로고
    • Smart polymeric gels: redefining the limits of biomedical devices
    • Chaterji S., Kwon K., and Park K. Smart polymeric gels: redefining the limits of biomedical devices. Prog Polym Sci 32 (2007) 1083-1122
    • (2007) Prog Polym Sci , vol.32 , pp. 1083-1122
    • Chaterji, S.1    Kwon, K.2    Park, K.3
  • 6
    • 36249024780 scopus 로고    scopus 로고
    • Hydrogel nanocomposites as remote-controlled biomaterials
    • Satarkar N.S., and Hilt J.Z. Hydrogel nanocomposites as remote-controlled biomaterials. Acta Biomater 4 (2008) 11-16
    • (2008) Acta Biomater , vol.4 , pp. 11-16
    • Satarkar, N.S.1    Hilt, J.Z.2
  • 7
    • 33751520245 scopus 로고    scopus 로고
    • Thermo- and pH-responsive polymers in drug delivery
    • Schmaljohann D. Thermo- and pH-responsive polymers in drug delivery. Adv Drug Deliv Rev 58 (2006) 1655-1670
    • (2006) Adv Drug Deliv Rev , vol.58 , pp. 1655-1670
    • Schmaljohann, D.1
  • 8
    • 33745135423 scopus 로고    scopus 로고
    • Hydrogels in biology and medicine: from molecular principles to bionanotechnology
    • Peppas N.A., Hilt J.Z., Khademhosseini A., and Langer R. Hydrogels in biology and medicine: from molecular principles to bionanotechnology. Adv Mater 18 (2006) 1345-1360
    • (2006) Adv Mater , vol.18 , pp. 1345-1360
    • Peppas, N.A.1    Hilt, J.Z.2    Khademhosseini, A.3    Langer, R.4
  • 9
    • 34547576746 scopus 로고    scopus 로고
    • Temperature-responsive cell culture surfaces for regenerative medicine with cell sheet engineering
    • Yamato M., Akiyama Y., Kobayashi J., Yang J., Kikuchi A., and Okano T. Temperature-responsive cell culture surfaces for regenerative medicine with cell sheet engineering. Prog Polym Sci 32 (2007) 1123-1133
    • (2007) Prog Polym Sci , vol.32 , pp. 1123-1133
    • Yamato, M.1    Akiyama, Y.2    Kobayashi, J.3    Yang, J.4    Kikuchi, A.5    Okano, T.6
  • 10
    • 0038136902 scopus 로고    scopus 로고
    • Temperature-sensitive poly(N-isopropylacrylamide) hydrogels with macroporous structure and fast response rate
    • Zhang J.T., Cheng S.X., Huang S.W., and Zhuo R.X. Temperature-sensitive poly(N-isopropylacrylamide) hydrogels with macroporous structure and fast response rate. Macromol Rapid Commun 24 (2003) 447-451
    • (2003) Macromol Rapid Commun , vol.24 , pp. 447-451
    • Zhang, J.T.1    Cheng, S.X.2    Huang, S.W.3    Zhuo, R.X.4
  • 11
    • 0041807971 scopus 로고    scopus 로고
    • Preparation of macroporous poly(N-isopropylacrylamide) hydrogel with improved temperature sensitivity
    • Zhang J.T., Cheng S.X., and Zhuo R.X. Preparation of macroporous poly(N-isopropylacrylamide) hydrogel with improved temperature sensitivity. J Polym Sci Part A: Polym Chem 41 (2003) 2390-2392
    • (2003) J Polym Sci Part A: Polym Chem , vol.41 , pp. 2390-2392
    • Zhang, J.T.1    Cheng, S.X.2    Zhuo, R.X.3
  • 12
    • 23944519694 scopus 로고    scopus 로고
    • Controlled release from and tissue response to physically bonded hydrogel nanoparticle assembly
    • Hu Z.B., Xia X.H., Marquez M., Weng H., and Tang L.P. Controlled release from and tissue response to physically bonded hydrogel nanoparticle assembly. Macromol Symp 227 (2005) 275-284
    • (2005) Macromol Symp , vol.227 , pp. 275-284
    • Hu, Z.B.1    Xia, X.H.2    Marquez, M.3    Weng, H.4    Tang, L.P.5
  • 13
    • 22944469105 scopus 로고    scopus 로고
    • Biodegradable thermoresponsive hydrogels for aqueous encapsulation and controlled release of hydrophilic model drugs
    • Huang X., and Lowe T.L. Biodegradable thermoresponsive hydrogels for aqueous encapsulation and controlled release of hydrophilic model drugs. Biomacromolecules 6 (2005) 2131-2139
    • (2005) Biomacromolecules , vol.6 , pp. 2131-2139
    • Huang, X.1    Lowe, T.L.2
  • 14
    • 64249159628 scopus 로고    scopus 로고
    • In vitro analysis of PNIPAAm-PEG, a novel, injectable scaffold for spinal cord repair
    • Comolli N., Neuhuber B., Fischer I., and Lowman A. In vitro analysis of PNIPAAm-PEG, a novel, injectable scaffold for spinal cord repair. Acta Biomater 5 (2009) 1046-1055
    • (2009) Acta Biomater , vol.5 , pp. 1046-1055
    • Comolli, N.1    Neuhuber, B.2    Fischer, I.3    Lowman, A.4
  • 15
    • 56349083623 scopus 로고    scopus 로고
    • Poly(N-isopropylacrylamide-co-acrylamide) cross-linked thermoresponsive microspheres obtained from preformed polymers: influence of the physico-chemical characteristics of drugs on their release profiles
    • Fundueanu G., Constantin M., and Ascenzi P. Poly(N-isopropylacrylamide-co-acrylamide) cross-linked thermoresponsive microspheres obtained from preformed polymers: influence of the physico-chemical characteristics of drugs on their release profiles. Acta Biomater 5 (2009) 363-373
    • (2009) Acta Biomater , vol.5 , pp. 363-373
    • Fundueanu, G.1    Constantin, M.2    Ascenzi, P.3
  • 16
    • 57549105074 scopus 로고    scopus 로고
    • Temperature responsive pore-filled membranes based on a BSA/poly(N-isopropylacrylamide) hydrogel
    • Zhang R., Bowyer A., Eisenthal R., and Hubble J. Temperature responsive pore-filled membranes based on a BSA/poly(N-isopropylacrylamide) hydrogel. Adv Polym Tech 27 (2008) 27-34
    • (2008) Adv Polym Tech , vol.27 , pp. 27-34
    • Zhang, R.1    Bowyer, A.2    Eisenthal, R.3    Hubble, J.4
  • 17
    • 43249118501 scopus 로고    scopus 로고
    • Preparation of temperature-sensitive poly(N-isopropylacrylamide)/beta-cyclodextrin-grafted polyethylenimine hydrogels for drug delivery
    • Zhang J.T., Xue Y.N., Gao F.Z., Huang S.W., and Zhuo R.X. Preparation of temperature-sensitive poly(N-isopropylacrylamide)/beta-cyclodextrin-grafted polyethylenimine hydrogels for drug delivery. J Appl Polym Sci 108 (2008) 3031-3037
    • (2008) J Appl Polym Sci , vol.108 , pp. 3031-3037
    • Zhang, J.T.1    Xue, Y.N.2    Gao, F.Z.3    Huang, S.W.4    Zhuo, R.X.5
  • 18
    • 0346256860 scopus 로고    scopus 로고
    • Advances in biomaterials, drug delivery, and bionanotechnology
    • Langer R., and Peppas N.A. Advances in biomaterials, drug delivery, and bionanotechnology. AICHE J 49 (2003) 2990-3006
    • (2003) AICHE J , vol.49 , pp. 2990-3006
    • Langer, R.1    Peppas, N.A.2
  • 19
    • 27744572795 scopus 로고    scopus 로고
    • A novel sol-gel strategy to prepare temperature-sensitive hydrogel for encapsulation of protein
    • Zhang J.T., Huang S.W., and Zhuo R.X. A novel sol-gel strategy to prepare temperature-sensitive hydrogel for encapsulation of protein. Colloid Polym Sci 284 (2005) 209-213
    • (2005) Colloid Polym Sci , vol.284 , pp. 209-213
    • Zhang, J.T.1    Huang, S.W.2    Zhuo, R.X.3
  • 20
    • 0032482152 scopus 로고    scopus 로고
    • Temperature-responsive gels and thermogelling polymer matrices for protein and peptide delivery
    • Bromberg L.E., and Ron E.S. Temperature-responsive gels and thermogelling polymer matrices for protein and peptide delivery. Adv Drug Deliv Rev 31 (1998) 197-221
    • (1998) Adv Drug Deliv Rev , vol.31 , pp. 197-221
    • Bromberg, L.E.1    Ron, E.S.2
  • 22
    • 0031754230 scopus 로고    scopus 로고
    • Enhanced loading and activity retention of bioactive proteins in hydrogel delivery systems
    • Gehrke S.H., Uhden L.H., and McBride J.F. Enhanced loading and activity retention of bioactive proteins in hydrogel delivery systems. J Control Release 55 (1998) 21-33
    • (1998) J Control Release , vol.55 , pp. 21-33
    • Gehrke, S.H.1    Uhden, L.H.2    McBride, J.F.3
  • 23
    • 0344306512 scopus 로고    scopus 로고
    • Macroporous poly(N-isopropylacrylamide) hydrogels with fast response rates and improved protein release properties
    • Cheng S.X., Zhang J.T., and Zhuo R.X. Macroporous poly(N-isopropylacrylamide) hydrogels with fast response rates and improved protein release properties. J Biomed Mater Res Part A 67A (2003) 96-103
    • (2003) J Biomed Mater Res Part A , vol.67 A , pp. 96-103
    • Cheng, S.X.1    Zhang, J.T.2    Zhuo, R.X.3
  • 25
    • 35948984499 scopus 로고    scopus 로고
    • Novel synthesis of macroporous poly(N-isopropylacrylamide) hydrogels using oil-in-water emulsions
    • Tokuyama H., and Kanehara A. Novel synthesis of macroporous poly(N-isopropylacrylamide) hydrogels using oil-in-water emulsions. Langmuir 23 (2007) 11246-11251
    • (2007) Langmuir , vol.23 , pp. 11246-11251
    • Tokuyama, H.1    Kanehara, A.2
  • 26
    • 46949101093 scopus 로고    scopus 로고
    • A liquid template method to prepare porous poly(N-isopropylacrylamide) hydrogel with superfast shrinking kinetics
    • Zhang J.T., and Jandt K.D. A liquid template method to prepare porous poly(N-isopropylacrylamide) hydrogel with superfast shrinking kinetics. Macromol Rapid Commun 29 (2008) 593-597
    • (2008) Macromol Rapid Commun , vol.29 , pp. 593-597
    • Zhang, J.T.1    Jandt, K.D.2
  • 27
    • 19344373131 scopus 로고    scopus 로고
    • Oil coating of hydrophobic surfaces from aqueous media: formation and kinetic study
    • Essafi W., Wong K., Bibette J., and Poulin P. Oil coating of hydrophobic surfaces from aqueous media: formation and kinetic study. J Colloid Interface Sci 286 (2005) 730-738
    • (2005) J Colloid Interface Sci , vol.286 , pp. 730-738
    • Essafi, W.1    Wong, K.2    Bibette, J.3    Poulin, P.4
  • 28
    • 0037465483 scopus 로고    scopus 로고
    • Wide-range control of deswelling time for thermosensitive poly(N-isopropylacrylamide) gel treated by freeze-drying
    • Kato N., Sakai Y., and Shibata S. Wide-range control of deswelling time for thermosensitive poly(N-isopropylacrylamide) gel treated by freeze-drying. Macromolecules 36 (2003) 961-963
    • (2003) Macromolecules , vol.36 , pp. 961-963
    • Kato, N.1    Sakai, Y.2    Shibata, S.3
  • 29
    • 33645388175 scopus 로고    scopus 로고
    • Nanoporous protein particles through templating mesoporous silica spheres
    • Wang Y.J., and Caruso F. Nanoporous protein particles through templating mesoporous silica spheres. Adv Mater 18 (2006) 795-800
    • (2006) Adv Mater , vol.18 , pp. 795-800
    • Wang, Y.J.1    Caruso, F.2
  • 30
    • 0025702686 scopus 로고
    • Thermal analysis of the volume phase transition with N-isopropylacrylamide gels
    • Otake K., Inomata H., Konno M., and Saito S. Thermal analysis of the volume phase transition with N-isopropylacrylamide gels. Macromolecules 23 (1990) 283-289
    • (1990) Macromolecules , vol.23 , pp. 283-289
    • Otake, K.1    Inomata, H.2    Konno, M.3    Saito, S.4
  • 31
    • 0035121247 scopus 로고    scopus 로고
    • Dynamic properties of temperature-sensitive poly(N-isopropylacrylamide) gel cross-linked through siloxane linkage
    • Zhang X.Z., and Zhuo R.X. Dynamic properties of temperature-sensitive poly(N-isopropylacrylamide) gel cross-linked through siloxane linkage. Langmuir 17 (2001) 12-16
    • (2001) Langmuir , vol.17 , pp. 12-16
    • Zhang, X.Z.1    Zhuo, R.X.2
  • 32
    • 33846411413 scopus 로고    scopus 로고
    • Effect of silk fibroin interpenetrating networks on swelling/deswelling kinetics and rheological properties of poly(N-isopropylacrylamide) hydrogels
    • Gil E.S., and Hudson S.M. Effect of silk fibroin interpenetrating networks on swelling/deswelling kinetics and rheological properties of poly(N-isopropylacrylamide) hydrogels. Biomacromolecules 8 (2007) 258-264
    • (2007) Biomacromolecules , vol.8 , pp. 258-264
    • Gil, E.S.1    Hudson, S.M.2
  • 33
    • 56349112744 scopus 로고    scopus 로고
    • Temperature-sensitive PVA/PNIPAAm semi-IPN hydrogels with enhanced responsive properties
    • Zhang J.T., Bhat R., and Jandt K.D. Temperature-sensitive PVA/PNIPAAm semi-IPN hydrogels with enhanced responsive properties. Acta Biomater 4 (2008) 488-497
    • (2008) Acta Biomater , vol.4 , pp. 488-497
    • Zhang, J.T.1    Bhat, R.2    Jandt, K.D.3
  • 34
    • 0343938456 scopus 로고    scopus 로고
    • Fundamental studies of a novel, biodegradable PEG-b-PLA hydrogel
    • Metters A.T., Anseth K.S., and Bowman C.N. Fundamental studies of a novel, biodegradable PEG-b-PLA hydrogel. Polymer 41 (2000) 3993-4004
    • (2000) Polymer , vol.41 , pp. 3993-4004
    • Metters, A.T.1    Anseth, K.S.2    Bowman, C.N.3
  • 35
    • 1542364229 scopus 로고    scopus 로고
    • Preparation and properties of poly(N-isoproplyacrylamide)/poly(N-isopropylacrylamide) interpenetrating polymer networks for drug delivery
    • Zhang J.T., Huang S.W., Cheng S.X., and Zhuo R.X. Preparation and properties of poly(N-isoproplyacrylamide)/poly(N-isopropylacrylamide) interpenetrating polymer networks for drug delivery. J Polym Sci Part A: Polym Chem 42 (2004) 1249-1254
    • (2004) J Polym Sci Part A: Polym Chem , vol.42 , pp. 1249-1254
    • Zhang, J.T.1    Huang, S.W.2    Cheng, S.X.3    Zhuo, R.X.4
  • 36
    • 0027591475 scopus 로고
    • Effect of comonomer hydrophilicity and ionization on the lower critical solution temperature of N-isopropylacrylamide copolymers
    • Feil H., Bae Y.H., Jan F.J., and Kim S.W. Effect of comonomer hydrophilicity and ionization on the lower critical solution temperature of N-isopropylacrylamide copolymers. Macromolecules 26 (1993) 2496-2500
    • (1993) Macromolecules , vol.26 , pp. 2496-2500
    • Feil, H.1    Bae, Y.H.2    Jan, F.J.3    Kim, S.W.4
  • 37
    • 0028414088 scopus 로고
    • Sigmoidal swelling profiles for temperature-responsive poly(N-isopropylacrylamide-co-butyl methacrylate) hydrogels
    • Yoshida R., Okuyama Y., Sakai K., Okano T., and Sakurai Y. Sigmoidal swelling profiles for temperature-responsive poly(N-isopropylacrylamide-co-butyl methacrylate) hydrogels. J Membr Sci 89 (1994) 267-277
    • (1994) J Membr Sci , vol.89 , pp. 267-277
    • Yoshida, R.1    Okuyama, Y.2    Sakai, K.3    Okano, T.4    Sakurai, Y.5
  • 38
    • 20444436467 scopus 로고    scopus 로고
    • Temperature sensitive poly [N-isopropylacrylamide-co(acryloyl beta-cyclodextrin)] for improved drug release
    • Zhang J.T., Huang S.W., Liu J., and Zhuo R.X. Temperature sensitive poly [N-isopropylacrylamide-co(acryloyl beta-cyclodextrin)] for improved drug release. Macromol Biosci 5 (2005) 192-196
    • (2005) Macromol Biosci , vol.5 , pp. 192-196
    • Zhang, J.T.1    Huang, S.W.2    Liu, J.3    Zhuo, R.X.4
  • 39
    • 0033106062 scopus 로고    scopus 로고
    • Temperature modulated protein release from pH/temperature-sensitive hydrogels
    • Park T.G. Temperature modulated protein release from pH/temperature-sensitive hydrogels. Biomaterials 20 (1999) 517-521
    • (1999) Biomaterials , vol.20 , pp. 517-521
    • Park, T.G.1
  • 40
    • 0028028760 scopus 로고
    • Estimation of temperature dependent pore size in poly(N-isopropylacrylamide) hydrogel beads
    • Park T.G., and Hoffman A.S. Estimation of temperature dependent pore size in poly(N-isopropylacrylamide) hydrogel beads. Biotechnol Prog 10 (1994) 82-86
    • (1994) Biotechnol Prog , vol.10 , pp. 82-86
    • Park, T.G.1    Hoffman, A.S.2
  • 41
    • 0036461227 scopus 로고    scopus 로고
    • Preparation and characterization of macroporous Poly(N-isopropylacrylamide) hydrogels for the controlled release of proteins
    • Zhuo R.X., and Li W. Preparation and characterization of macroporous Poly(N-isopropylacrylamide) hydrogels for the controlled release of proteins. J Polym Sci, Part A: Polym Chem 41 (2003) 152-159
    • (2003) J Polym Sci, Part A: Polym Chem , vol.41 , pp. 152-159
    • Zhuo, R.X.1    Li, W.2
  • 42
    • 1542358202 scopus 로고    scopus 로고
    • Synthesis, characterization and controlled drug release of thermosensitive IPN-PNIPAAm hydrogels
    • Zhang X.Z., Wu D.Q., and Chu C.C. Synthesis, characterization and controlled drug release of thermosensitive IPN-PNIPAAm hydrogels. Biomaterials 25 (2004) 3793-3805
    • (2004) Biomaterials , vol.25 , pp. 3793-3805
    • Zhang, X.Z.1    Wu, D.Q.2    Chu, C.C.3
  • 43
    • 33745685843 scopus 로고    scopus 로고
    • Macroporous poly (N-isopropylacrylamide) hydrogels with adjustable size "cut-off" for the efficient and reversible immobilization of biomacromolecules
    • Fanger C., Wack H., and Ulbricht M. Macroporous poly (N-isopropylacrylamide) hydrogels with adjustable size "cut-off" for the efficient and reversible immobilization of biomacromolecules. Macromol Biosci 6 (2006) 393-402
    • (2006) Macromol Biosci , vol.6 , pp. 393-402
    • Fanger, C.1    Wack, H.2    Ulbricht, M.3
  • 44
    • 0012454921 scopus 로고
    • Electric polarization in proteins-dielectric dispersion and Kerr effect studies of isoionic bovine serum albumin
    • Maser P., Squire P.G., and O'Konski C.T. Electric polarization in proteins-dielectric dispersion and Kerr effect studies of isoionic bovine serum albumin. J Phys Chem 70 (1966) 744
    • (1966) J Phys Chem , vol.70 , pp. 744
    • Maser, P.1    Squire, P.G.2    O'Konski, C.T.3


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