Rotary culture promotes the proliferation of MCF-7 cells encapsulated in three-dimensional collagen-alginate hydrogels via activation of the ERK1/2-MAPK pathway

Biomedical Materials

Volumn 7, Issue 1, 2012, Pages

  Zheng, Hongxia ^a   Tian, Weiming ^a,b   Yan, Hongji ^a   Yue, Lei ^a   Zhang, Yao ^a   Han, Fengtong ^a   Chen, Xiongbiao ^c   Li, Yu ^a  

^a HARBIN INSTITUTE OF TECHNOLOGY   (China)

^b Chinese Astronaut Research and Training Center   (China)

^c UNIVERSITY OF SASKATCHEWAN   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CELL PROLIFERATION; CELLS; COLLAGEN; FLOW CYTOMETRY; HYDROGELS; THREE DIMENSIONAL; TISSUE;

CONTROL GROUPS; CULTURE SYSTEMS; CYCLIND1; CYTOSKELETONS; FUNCTIONAL TISSUE; INDIRECT IMMUNOFLUORESCENCE; MCF-7 CELLS; MITOTIC SPINDLE; MTT ASSAYS; PROLIFERATION RATE; STATIC CULTURE; THREE-DIMENSIONAL (3D);

CELL CULTURE;

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; ALGINIC ACID; COLLAGEN; CYCLIN D1; CYCLINE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; BIOMIMETIC MATERIAL; GLUCURONIC ACID; HEXURONIC ACID; TISSUE SCAFFOLD;

ARTICLE; CELL CULTURE; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL CYCLE S PHASE; CELL ENCAPSULATION; CELL PROLIFERATION; CELL STRAIN MCF 7; CONTROLLED STUDY; CYTOSKELETON; ENZYME ACTIVATION; FEMALE; FLOW CYTOMETRY; HUMAN; HUMAN CELL; HYDROGEL; IMMUNOFLUORESCENCE; MITOSIS SPINDLE; PROTEIN EXPRESSION; SPHEROID CELL; BREAST TUMOR; CHEMISTRY; EXTRACELLULAR MATRIX; MATERIALS TESTING; MECHANOTRANSDUCTION; METHODOLOGY; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; ROTATION; SIGNAL TRANSDUCTION; TISSUE ENGINEERING; TUMOR CELL LINE;

ALGINATES; BIOMIMETIC MATERIALS; BREAST NEOPLASMS; CELL LINE, TUMOR; CELL PROLIFERATION; COLLAGEN; EXTRACELLULAR MATRIX; GLUCURONIC ACID; HEXURONIC ACIDS; HUMANS; HYDROGELS; MAP KINASE SIGNALING SYSTEM; MATERIALS TESTING; MECHANOTRANSDUCTION, CELLULAR; ROTATION; TISSUE ENGINEERING; TISSUE SCAFFOLDS;

EID: 84856473425     PISSN: 17486041     EISSN: 1748605X     Source Type: Journal    
DOI: 10.1088/1748-6041/7/1/015003     Document Type: Article

References (49)

1. Cuzick J et al 2011 Preventive therapy for breast cancer: a consensus statement Lancet Oncol. 12 496-503
2. Li Q, Chow A B and Mattingly R R 2010 Three-dimensional overlay culture models of human breast cancer reveal a critical sensitivity to mitogen-activated protein kinase inhibitors J. Pharmacol. Exp. Ther. 332 821-8
3. Yamada K M and Cukierman E 2007 Modeling tissue morphogenesis and cancer in 3D Cell 130 601-10
4. Elliott N T and Yuan F 2010 A review of three-dimensional in vitro tissue models for drug discovery and transport studies J. Pharm. Sci. 100 59-74
5. Fischbach C, Chen R, Matsumoto T, Schmelzle T, Brugge J S, Polverini P J and Mooney D J 2007 Engineering tumors with 3D scaffolds Nature Methods 4 855-60 (Pubitemid 350055585)
6. Kim J B, Stein R and O'Hare M J 2004 Three-dimensional in vitro tissue culture models of breast cancer - a review Breast Cancer Res. Treat. 85 281-91 (Pubitemid 38987263)
7. McGuigan A P, Bruzewicz D A, Glavan A, Butte M J and Whitesides G M 2008 Cell encapsulation in sub-mm sized gel modules using replica molding PLoS One 3 e2258
8. Frampton J P, Hynd M R, Shuler M L and Shain W 2011 Fabrication and optimization of alginate hydrogel constructs for use in 3D neural cell culture Biomed. Mater. 6 015002
9. Wang J et al 2009 Simulated microgravity promotes cellular senescence via oxidant stress in rat PC12 cells Neurochem. Int. 55 710-6
10. Hunt N C and Grover L M 2010 Cell encapsulation using biopolymer gels for regenerative medicine Biotechnol. Lett. 32 733-42
11. Dhiman H K, Ray A R and Panda A K 2004 Characterization and evaluation of chitosan matrix for in vitro growth of MCF-7 breast cancer cell lines Biomaterials 25 5147-54 (Pubitemid 38510400)
12. Cukierman E, Pankov R and Yamada K M 2002 Cell interactions with three-dimensional matrices Curr. Opin. Cell Biol. 14 633-9 (Pubitemid 35247748)
13. Cukierman E, Pankov R, Stevens D R and Yamada K M 2001 Taking cell-matrix adhesions to the third dimension Science 294 1708-12 (Pubitemid 33104840)
14. Alsberg E, Kong H J, Hirano Y, Smith M K, Albeiruti A and Mooney D J 2003 Regulating bone formation via controlled scaffold degradation J. Dent. Res. 82 903-8 (Pubitemid 41756872)
15. Wu Y M, Tang J, Zhao P, Chen Z N and Jiang J L 2009 Morphological changes and molecular expressions of hepatocellular carcinoma cells in three-dimensional culture model Exp. Mol. Pathol. 87 133-40
16. Kuo C K and Ma P X 2001 Ionically crosslinked alginate hydrogels as scaffolds for tissue engineering: part 1. Structure, gelation rate and mechanical properties Biomaterials 22 511-21 (Pubitemid 32015873)
17. Matthew I R, Browne R M, Frame J W and Millar B G 1995 Subperiosteal behaviour of alginate and cellulose wound dressing materials Biomaterials 16 275-8
18. Larreta-Garde V and Panouille M 2009 Gelation behaviour of gelatin and alginate mixtures Food Hydrocolloids 23 1074-80
19. Draget K I, Skjak-Braek G and Smidsrod O 1997 Alginate based new materials Int. J. Biol. Macromol. 21 47-55 (Pubitemid 27368019)
20. Dhiman H K, Ray A R and Panda A K 2005 Three-dimensional chitosan scaffold-based MCF-7 cell culture for the determination of the cytotoxicity of tamoxifen Biomaterials 26 979-86 (Pubitemid 39213976)
21. Unsworth B R and Lelkes P I 1998 Growing tissues in microgravity Nature Med. 4 901-7 (Pubitemid 28364028)
22. Hammond T G and Hammond J M 2001 Optimized suspension culture: the rotating-wall vessel Am. J. Physiol. Renal Physiol. 281 F12-25
23. Waters S L, Cummings L J, Shakesheff K M and Rose F R 2006 Tissue growth in a rotating bioreactor: part I. Mechanical stability Math. Med. Biol. 23 311-37 (Pubitemid 44896817)
24. Boehrs J, Zaharias R S, Laffoon J, Ko Y J and Schneider G B 2008 Three-dimensional culture environments enhance osteoblast differentiation J. Prosthodont. 17 517-21
25. Li S, Ma Z, Niu Z, Qian H, Xuan D, Hou R and Ni L 2009 NASA-approved rotary bioreactor enhances proliferation and osteogenesis of human periodontal ligament stem cells Stem Cells Dev. 18 1273-82
26. Gao H L, Lin T, Kang H J and Chen X B 2007 Synthesis, spectra and crystal structure of complex [Ag(chlsp)(2)](CF3CO2) Chin. J. Inorg. Chem. 23 1429-31
27. Bucaro M A, Fertala J, Adams C S, Steinbeck M, Ayyaswamy P, Mukundakrishnan K, Shapiro I M and Risbud M V 2004 Bone cell survival in microgravity: evidence that modeled microgravity increases osteoblast sensitivity to apoptogens Ann. NY Acad. Sci. 1027 64-73 (Pubitemid 39656759)
28. Bai X P, Zheng H X, Fang R, Wang T R, Hou X L, Li Y, Chen X B and Tian W M 2011 Fabrication of engineered heart tissue grafts from alginate/collagen barium composite microbeads Biomed. Mater. 6 045002
29. Schwarz R P, Goodwin T J and Wolf D A 1992 Cell culture for three-dimensional modeling in rotating-wall vessels: an application of simulated microgravity J. Tissue Cult. Methods 14 51-7
30. Bucaro M A, Zahm A M, Risbud M V, Ayyaswamy P S, Mukundakrishnan K, Steinbeck M J, Shapiro I M and Adams C S 2007 The effect of simulated microgravity on osteoblasts is independent of the induction of apoptosis J. Cell Biochem. 102 483-95 (Pubitemid 47519421)
31. Carlsson S I, Bertilaccio M T, Ballabio E and Maier J A 2003 Endothelial stress by gravitational unloading: effects on cell growth and cytoskeletal organization Biochim. Biophys. Acta 1642 173-9 (Pubitemid 37315660)
32. Hughes-Fulford M 2003 Function of the cytoskeleton in gravisensing during spaceflight Adv. Space Res. 32 1585-93 (Pubitemid 38034110)
33. Kim J B 2005 Three-dimensional tissue culture models in cancer biology Semin. Cancer Biol. 15 365-77
34. Ishikawa M, Sekine K, Okamura A, Zheng Y W, Ueno Y, Koike N, Tanaka J and Taniguchi H 2011 Reconstitution of hepatic tissue architectures from fetal liver cells obtained from a three-dimensional culture with a rotating wall vessel bioreactor J. Biosci. Bioeng. 111 711-8
35. Yi Z C, Xia B, Xue M, Zhang G Y, Wang H, Zhou H M, Sun Y and Zhuang F Y 2009 Simulated microgravity inhibits the proliferation of K562 erythroleukemia cells but does not result in apoptosis Adv. Space Res. 44 233-44
36. Takeda M, Magaki T, Okazaki T, Kawahara Y, Manabe T, Yuge L and Kurisu K 2009 Effects of simulated microgravity on proliferation and chemosensitivity in malignant glioma cells Neurosci. Lett. 463 54-9
37. Qian A R, Zhang W, Xie L, Weng Y Y, Yang P F, Wang Z, Hu L F, Xu H Y, Tian Z C and Shang P 2008 Simulated weightlessness alters biological characteristics of human breast cancer cell line MCF-7 Acta Astronaut. 63 947-58
38. Grimm D et al 2002 Simulated microgravity alters differentiation and increases apoptosis in human follicular thyroid carcinoma cells FASEB J. 16 604-6
39. Coussens L M, Fingleton B and Matrisian L M 2002 Matrix metalloproteinase inhibitors and cancer: trials and tribulations Science 295 2387-92 (Pubitemid 34270240)
40. Slentz D H, Truskey G A and Kraus W E 2001 Effects of chronic exposure to simulated microgravity on skeletal muscle cell proliferation and differentiation In Vitro Cell Dev. Biol. Anim. 37 148-56 (Pubitemid 32423835)
41. Plett P A, Frankovitz S M, Abonour R and Orschell-Traycoff C M 2001 Proliferation of human hematopoietic bone marrow cells in simulated microgravity In Vitro Cell Dev. Biol. Anim. 37 73-8 (Pubitemid 32327953)
42. Chiu B, Wan J Z, Abley D and Akabutu J 2005 Induction of vascular endothelial phenotype and cellular proliferation from human cord blood stem cells cultured in simulated microgravity Acta Astronaut. 56 918-22 (Pubitemid 40467248)
43. Huang Y, Dai Z Q, Ling S K, Zhang H Y, Wan Y M and Li Y H 2009 Gravity, a regulation factor in the differentiation of rat bone marrow mesenchymal stem cells J. Biomed. Sci. 16 87
44. Qian A R et al 2008 Gravitational environment produced by a superconducting magnet affects osteoblast morphology and functions Acta Astronaut. 63 929-46
45. Clement J Q, Lacy S M and Wilson B L 2008 Gene expression profiling of human epidermal keratinocytes in simulated microgravity and recovery cultures Genomics Proteomics Bioinformatics 6 8-28 (Pubitemid 351847758)
46. Leonardi E, Girlando S, Serio G, Mauri F A, Perrone G, Scampini S, Dalla Palma P and Barbareschi M 1992 PCNA and Ki67 expression in breast carcinoma: correlations with clinical and biological variables J. Clin. Pathol. 45 416-9
47. Bravo R, Frank R, Blundell P A and Macdonald-Bravo H 1987 Cyclin/PCNA is the auxiliary protein of DNA polymerase-delta Nature 326 515-7 (Pubitemid 17055498)
48. Chang L and Karin M 2001 Mammalian MAP kinase signalling cascades Nature 410 37-40 (Pubitemid 32225829)
49. Loesberg W A, Walboomers X F, van Loon J J and Jansen J A 2008 Simulated microgravity activates MAPK pathways in fibroblasts cultured on microgrooved surface topography Cell Motil. Cytoskeleton 65 116-29 (Pubitemid 351272973)