Simulated microgravity activates MAPK pathways in fibroblasts cultured on microgrooved surface topography

Cell Motility and the Cytoskeleton

Volumn 65, Issue 2, 2008, Pages 116-129

  Loesberg, W A ^a   Walboomers, X F ^a   Van Loon, J J W A ^b   Jansen, John A ^a  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^b VU UNIVERSITY AMSTERDAM   (Netherlands)

Author keywords

Connective tissue; Fibroblast cells; Microgravity; Microtexture

Indexed keywords

ALPHA1 INTEGRIN; BETA1 INTEGRIN; BETA3 INTEGRIN; COLLAGEN TYPE 1; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; STRESS ACTIVATED PROTEIN KINASE;

ANIMAL CELL; ARTICLE; CELL CULTURE; CELL FUNCTION; CELL MOTILITY; CELL SHAPE; CELL STRUCTURE; CONTROLLED STUDY; FIBROBLAST; FLUORESCENCE MICROSCOPE; IMAGE ANALYSIS; IMMUNOBLOTTING; MALE; MICROGRAVITY; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SCANNING ELECTRON MICROSCOPY; TOPOGRAPHY; UPREGULATION;

ANIMALS; ANTIGENS, CD29; BLOTTING, WESTERN; CELL CULTURE TECHNIQUES; CELLS, CULTURED; DERMIS; ELECTROPHORESIS, POLYACRYLAMIDE GEL; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FIBROBLASTS; INTEGRIN ALPHA1; INTEGRIN BETA3; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MALE; MAP KINASE SIGNALING SYSTEM; MICROSCOPY, ELECTRON, SCANNING; MICROSCOPY, FLUORESCENCE; RATS; RATS, WISTAR; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RHO GTP-BINDING PROTEINS; WEIGHTLESSNESS;

EID: 39449111484     PISSN: 08861544     EISSN: 10970169     Source Type: Journal    
DOI: 10.1002/cm.20248     Document Type: Article

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