-
1
-
-
21844454175
-
Bladder cancer clinical trials
-
Lerner SP: Bladder cancer clinical trials. Urol Oncol 2005;23:275-279.
-
(2005)
Urol Oncol
, vol.23
, pp. 275-279
-
-
Lerner, S.P.1
-
2
-
-
0033857218
-
Gemcitabine and cisplatin versus methotrexate, vinblastine, doxorubicin, and cisplatin in advanced or metastatic bladder cancer: Results of a large, randomized, multinational, multicenter, phase III study
-
von der Maase H, Hansen SW, Roberts JT, et al: Gemcitabine and cisplatin versus methotrexate, vinblastine, doxorubicin, and cisplatin in advanced or metastatic bladder cancer: results of a large, randomized, multinational, multicenter, phase III study. J Clin Oncol 2000;18:3068-3077.
-
(2000)
J Clin Oncol
, vol.18
, pp. 3068-3077
-
-
Von Der Maase, H.1
Hansen, S.W.2
Roberts, J.T.3
-
3
-
-
0030025773
-
Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours
-
Graeber TG, Osmanian C, Jacks T, et al: Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours. Nature 1996;379:88-91.
-
(1996)
Nature
, vol.379
, pp. 88-91
-
-
Graeber, T.G.1
Osmanian, C.2
Jacks, T.3
-
4
-
-
0032053823
-
The unique physiology of solid tumors: Opportunities (and problems) for cancer therapy
-
Brown JM, Giaccia AJ: The unique physiology of solid tumors: opportunities (and problems) for cancer therapy. Cancer Res 1998;58:1408-1416.
-
(1998)
Cancer Res
, vol.58
, pp. 1408-1416
-
-
Brown, J.M.1
Giaccia, A.J.2
-
7
-
-
56149089262
-
Hypoxia-inducible factor 1 and cancer pathogenesis
-
Semenza GL: Hypoxia-inducible factor 1 and cancer pathogenesis. IUBMB Life 2008;60:591-597.
-
(2008)
IUBMB Life
, vol.60
, pp. 591-597
-
-
Semenza, G.L.1
-
8
-
-
0033571682
-
Overexpression of hypoxia-inducible factor 1alpha in common human cancers and their metastases
-
Zhong H, De Marzo AM, Laughner E, et al: Overexpression of hypoxia-inducible factor 1alpha in common human cancers and their metastases. Cancer Res 1999;59:5830-5835.
-
(1999)
Cancer Res
, vol.59
, pp. 5830-5835
-
-
Zhong, H.1
De Marzo, A.M.2
Laughner, E.3
-
9
-
-
0034282518
-
Overexpression of hypoxia-inducible factor 1alpha is a marker for an unfavorable prognosis in early-stage invasive cervical cancer
-
Birner P, Schindl M, Obermair A, et al: Overexpression of hypoxia-inducible factor 1alpha is a marker for an unfavorable prognosis in early-stage invasive cervical cancer. Cancer Res 2000;60:4693-4696.
-
(2000)
Cancer Res
, vol.60
, pp. 4693-4696
-
-
Birner, P.1
Schindl, M.2
Obermair, A.3
-
10
-
-
3142534607
-
Hypoxia-inducible factor 1 alpha expression correlates with angiogenesis and unfavorable prognosis in bladder cancer
-
Theodoropoulos VE, Lazaris A, Sofras F, et al: Hypoxia-inducible factor 1 alpha expression correlates with angiogenesis and unfavorable prognosis in bladder cancer. Eur Urol 2004;46:200-208.
-
(2004)
Eur Urol
, vol.46
, pp. 200-208
-
-
Theodoropoulos, V.E.1
Lazaris, A.2
Sofras, F.3
-
11
-
-
77950916788
-
Evaluation of relationship between HIF-1alpha immunoreactivity and stage, grade, angiogenic profile and proliferative index in bladder urothelial carcinomas
-
Deniz H, Karakok M, Yagci F, et al: Evaluation of relationship between HIF-1alpha immunoreactivity and stage, grade, angiogenic profile and proliferative index in bladder urothelial carcinomas. Int Urol Nephrol 2010;42:103-107.
-
(2010)
Int Urol Nephrol
, vol.42
, pp. 103-107
-
-
Deniz, H.1
Karakok, M.2
Yagci, F.3
-
12
-
-
0028109332
-
YC-1, a novel activator of platelet guanylate cyclase
-
Ko FN, Wu CC, Kuo SC, et al: YC-1, a novel activator of platelet guanylate cyclase. Blood 1994;84:4226-4233.
-
(1994)
Blood
, vol.84
, pp. 4226-4233
-
-
Ko, F.N.1
Wu, C.C.2
Kuo, S.C.3
-
14
-
-
0035871942
-
Inhibitory effect of YC-1 on the hypoxic induction of erythropoietin and vascular endothelial growth factor in Hep3B cells
-
Chun YS, Yeo EJ, Choi E, et al: Inhibitory effect of YC-1 on the hypoxic induction of erythropoietin and vascular endothelial growth factor in Hep3B cells. Biochem Pharmacol 2001;61:947-954.
-
(2001)
Biochem Pharmacol
, vol.61
, pp. 947-954
-
-
Chun, Y.S.1
Yeo, E.J.2
Choi, E.3
-
15
-
-
33846990665
-
A domain responsible for HIF-1alpha degradation by YC-1, a novel anticancer agent
-
Kim HL, Yeo EJ, Chun YS, et al: A domain responsible for HIF-1alpha degradation by YC-1, a novel anticancer agent. Int J Oncol 2006;29:255-260.
-
(2006)
Int J Oncol
, vol.29
, pp. 255-260
-
-
Kim, H.L.1
Yeo, E.J.2
Chun, Y.S.3
-
17
-
-
21344454920
-
YC-1-inhibited proliferation of rat mesangial cells through suppression of cyclin D1-independent of cGMP pathway and partially reversed by p38 MAPK inhibitor
-
Chiang WC, Teng CM, Lin SL, et al: YC-1-inhibited proliferation of rat mesangial cells through suppression of cyclin D1-independent of cGMP pathway and partially reversed by p38 MAPK inhibitor. Eur J Pharmacol 2005;517:1-10.
-
(2005)
Eur J Pharmacol
, vol.517
, pp. 1-10
-
-
Chiang, W.C.1
Teng, C.M.2
Lin, S.L.3
-
18
-
-
33747888997
-
Suppression of hypoxia inducible factor-1alpha (HIF-1alpha) by YC-1 is dependent on murine double minute 2 (Mdm2)
-
Lau CK, Yang ZF, Lam CT, et al: Suppression of hypoxia inducible factor-1alpha (HIF-1alpha) by YC-1 is dependent on murine double minute 2 (Mdm2). Biochem Biophys Res Commun 2006;348:1443-1448.
-
(2006)
Biochem Biophys Res Commun
, vol.348
, pp. 1443-1448
-
-
Lau, C.K.1
Yang, Z.F.2
Lam, C.T.3
-
19
-
-
57749106966
-
A novel mode of action of YC-1 in HIF inhibition: Stimulation of FIH-dependent p300 dissociation from HIF-1{alpha}
-
Li SH, Shin DH, Chun YS, et al: A novel mode of action of YC-1 in HIF inhibition: stimulation of FIH-dependent p300 dissociation from HIF-1{alpha}. Mol Cancer Ther 2008;7:3729-3738.
-
(2008)
Mol Cancer Ther
, vol.7
, pp. 3729-3738
-
-
Li, S.H.1
Shin, D.H.2
Chun, Y.S.3
-
20
-
-
0030816109
-
Hypoxia-inducible factor-1 modulates gene expression in solid tumors and influences both angiogenesis and tumor growth
-
Maxwell PH, Dachs GU, Gleadle JM, et al: Hypoxia-inducible factor-1 modulates gene expression in solid tumors and influences both angiogenesis and tumor growth. Proc Natl Acad Sci USA 1997;94:8104-8109.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 8104-8109
-
-
Maxwell, P.H.1
Dachs, G.U.2
Gleadle, J.M.3
-
21
-
-
43549124115
-
Hypoxiainducible factor-1alpha expression correlates with focal macrophage infiltration, angiogenesis and unfavourable prognosis in urothelial carcinoma
-
Chai CY, Chen WT, Hung WC, et al: Hypoxiainducible factor-1alpha expression correlates with focal macrophage infiltration, angiogenesis and unfavourable prognosis in urothelial carcinoma. J Clin Pathol 2008;61:658-664.
-
(2008)
J Clin Pathol
, vol.61
, pp. 658-664
-
-
Chai, C.Y.1
Chen, W.T.2
Hung, W.C.3
-
22
-
-
0037414180
-
YC-1: A potential anticancer drug targeting hypoxiainducible factor 1
-
Yeo EJ, Chun YS, Cho YS, et al: YC-1: a potential anticancer drug targeting hypoxiainducible factor 1. J Natl Cancer Inst 2003;95:516-525.
-
(2003)
J Natl Cancer Inst
, vol.95
, pp. 516-525
-
-
Yeo, E.J.1
Chun, Y.S.2
Cho, Y.S.3
-
23
-
-
33847164484
-
Effects of YC-1 on hypoxia-inducible factor 1-driven transcription activity, cell proliferative vitality, and apoptosis in hypoxic human pancreatic cancer cells
-
Zhao Q, Du J, Gu H, et al: Effects of YC-1 on hypoxia-inducible factor 1-driven transcription activity, cell proliferative vitality, and apoptosis in hypoxic human pancreatic cancer cells. Pancreas 2007;34:242-247.
-
(2007)
Pancreas
, vol.34
, pp. 242-247
-
-
Zhao, Q.1
Du, J.2
Gu, H.3
-
24
-
-
79960981590
-
Effects of YC-1 targeting hypoxia-inducible factor 1 alpha in esophageal squamous carcinoma cell line Eca109 cells
-
Feng Y, Zhu H, Ling T, et al: Effects of YC-1 targeting hypoxia-inducible factor 1 alpha in esophageal squamous carcinoma cell line Eca109 cells. Cell Biol Int 2011;35:491-497.
-
(2011)
Cell Biol Int
, vol.35
, pp. 491-497
-
-
Feng, Y.1
Zhu, H.2
Ling, T.3
-
25
-
-
8044253996
-
Structural and functional analysis of hypoxia-inducible factor 1
-
Semenza GL, Agani F, Booth G, et al: Structural and functional analysis of hypoxia-inducible factor 1. Kidney Int 1997;51:553-555.
-
(1997)
Kidney Int
, vol.51
, pp. 553-555
-
-
Semenza, G.L.1
Agani, F.2
Booth, G.3
-
26
-
-
37349002494
-
Anticancer mechanisms of YC-1 in human lung cancer cell line, NCI-H226
-
Chen CJ, Hsu MH, Huang LJ, et al: Anticancer mechanisms of YC-1 in human lung cancer cell line, NCI-H226. Biochem Pharmacol 2008;75:360-368.
-
(2008)
Biochem Pharmacol
, vol.75
, pp. 360-368
-
-
Chen, C.J.1
Hsu, M.H.2
Huang, L.J.3
-
27
-
-
24944488029
-
Dual-specificity phosphatase DUSP1 protects overactivation of hypoxia-inducible factor 1 through inactivating ERK MAPK
-
Liu C, Shi Y, Du Y, et al: Dual-specificity phosphatase DUSP1 protects overactivation of hypoxia-inducible factor 1 through inactivating ERK MAPK. Exp Cell Res 2005;309:410-418.
-
(2005)
Exp Cell Res
, vol.309
, pp. 410-418
-
-
Liu, C.1
Shi, Y.2
Du, Y.3
-
28
-
-
33847267684
-
A critical role for p38 MAP kinase in NF-kappaB signaling during intermittent hypoxia/reoxygenation
-
Ryan S, McNicholas WT, Taylor CT: A critical role for p38 MAP kinase in NF-kappaB signaling during intermittent hypoxia/reoxygenation. Biochem Biophys Res Commun 2007;355:728-733.
-
(2007)
Biochem Biophys Res Commun
, vol.355
, pp. 728-733
-
-
Ryan, S.1
McNicholas, W.T.2
Taylor, C.T.3
|