메뉴 건너뛰기




Volumn 34, Issue 2, 2007, Pages 242-247

Effects of YC-1 on hypoxia-inducible factor 1-driven transcription activity, cell proliferative vitality, and apoptosis in hypoxic human pancreatic cancer cells

Author keywords

3 (5 hydroxymethyl 2 furyl) 1 benzyl indazole; Apoptosis; Hypoxia inducible factor 1; Pancreatic cancer; Proliferative vitality

Indexed keywords

1 BENZYL 3 (5 HYDROXYMETHYL 2 FURYL)INDAZOLE; GLUCOSE 6 PHOSPHATE ISOMERASE; HYPOXIA INDUCIBLE FACTOR 1; MESSENGER RNA; VASCULOTROPIN;

EID: 33847164484     PISSN: 08853177     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.mpa.0000250135.95144.b6     Document Type: Article
Times cited : (42)

References (27)
  • 2
    • 0030025773 scopus 로고    scopus 로고
    • Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumors
    • Graeber TG, Osmanian C, Jacks T, et al. Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumors. Nature. 1996;379:88-91.
    • (1996) Nature , vol.379 , pp. 88-91
    • Graeber, T.G.1    Osmanian, C.2    Jacks, T.3
  • 3
    • 0032053823 scopus 로고    scopus 로고
    • The unique physiology of solid tumors: Opportunities (and problems) for cancer therapy
    • Brown JM, Giaccia AJ. The unique physiology of solid tumors: opportunities (and problems) for cancer therapy. Cancer Res. 1998;58:1408-1416.
    • (1998) Cancer Res , vol.58 , pp. 1408-1416
    • Brown, J.M.1    Giaccia, A.J.2
  • 4
    • 0033617186 scopus 로고    scopus 로고
    • Mitogen-activated protein kinase phosphatase-1 (MKP-1) expression is induced by low oxygen conditions found in solid tumor microenvironments: A candidate MKP for the inactivation of hypoxia-inducible stress-activated protein kinase/c-Jun N-terminal protein kinase activity
    • Laderoute KR, Mendonca HL, Calaoagan JM, et al. Mitogen-activated protein kinase phosphatase-1 (MKP-1) expression is induced by low oxygen conditions found in solid tumor microenvironments: a candidate MKP for the inactivation of hypoxia-inducible stress-activated protein kinase/c-Jun N-terminal protein kinase activity. J Biol Chem. 1999;274:12890-12897.
    • (1999) J Biol Chem , vol.274 , pp. 12890-12897
    • Laderoute, K.R.1    Mendonca, H.L.2    Calaoagan, J.M.3
  • 5
    • 0037215306 scopus 로고    scopus 로고
    • Hypoxia inducible factor 1 regulates vascular endothelial growth factor expression in human pancreatic cancer
    • Buchler P, Reber HA, Buchler M, et al. Hypoxia inducible factor 1 regulates vascular endothelial growth factor expression in human pancreatic cancer. Pancreas. 2003;26:56-64.
    • (2003) Pancreas , vol.26 , pp. 56-64
    • Buchler, P.1    Reber, H.A.2    Buchler, M.3
  • 6
    • 0033975850 scopus 로고    scopus 로고
    • Hypoxia response element of the human vascular endothelial growth factor gene mediates transcriptional regulation by nitric oxide: Control of hypoxia-inducible factor-1 activity by nitric oxide
    • Kimura H, Weisz A, Kurashima Y, et al. Hypoxia response element of the human vascular endothelial growth factor gene mediates transcriptional regulation by nitric oxide: control of hypoxia-inducible factor-1 activity by nitric oxide. Blood. 2000;95:189-197.
    • (2000) Blood , vol.95 , pp. 189-197
    • Kimura, H.1    Weisz, A.2    Kurashima, Y.3
  • 7
    • 0033605676 scopus 로고    scopus 로고
    • Inhibition of hypoxia-inducible factor 1 activation by carbon monoxide and nitric oxide. Implication for oxygen sensing and signaling
    • Huang LE, Willmore WG, Gu J, et al. Inhibition of hypoxia-inducible factor 1 activation by carbon monoxide and nitric oxide. Implication for oxygen sensing and signaling. J Biol Chem. 1999;274:9038-9044.
    • (1999) J Biol Chem , vol.274 , pp. 9038-9044
    • Huang, L.E.1    Willmore, W.G.2    Gu, J.3
  • 8
    • 0028109332 scopus 로고
    • YC-1, a novel activator of platelet guanylate cyclase
    • Ko FN, Wu CC, Kuo SC, et al. YC-1, a novel activator of platelet guanylate cyclase. Blood. 1994;84:4226-4233.
    • (1994) Blood , vol.84 , pp. 4226-4233
    • Ko, F.N.1    Wu, C.C.2    Kuo, S.C.3
  • 9
    • 10744229867 scopus 로고    scopus 로고
    • Cobalt chloride and low oxygen tension trigger differentiation of acute myeloid leukemic cells: Possible mediation of hypoxia-inducible factor-1α
    • Huang Y, Du KM, Xue ZH, et al. Cobalt chloride and low oxygen tension trigger differentiation of acute myeloid leukemic cells: possible mediation of hypoxia-inducible factor-1α. Leukemia. 2003;17:2065-2073.
    • (2003) Leukemia , vol.17 , pp. 2065-2073
    • Huang, Y.1    Du, K.M.2    Xue, Z.H.3
  • 10
    • 0033571682 scopus 로고    scopus 로고
    • Overexpression of hypoxia-inducible factor-1α in common human cancers and their metastases
    • Zhong H, De Marzo AM, Laughner E, et al. Overexpression of hypoxia-inducible factor-1α in common human cancers and their metastases. Cancer Res. 1999;59:5830-5835.
    • (1999) Cancer Res , vol.59 , pp. 5830-5835
    • Zhong, H.1    De Marzo, A.M.2    Laughner, E.3
  • 13
    • 0033233243 scopus 로고    scopus 로고
    • 2 homeostasis by hypoxia-inducible factor 1
    • 2 homeostasis by hypoxia-inducible factor 1. Annu Rev Cell Dev Biol. 1999;15:551-578.
    • (1999) Annu Rev Cell Dev Biol , vol.15 , pp. 551-578
    • Semenza, G.L.1
  • 14
    • 0033587146 scopus 로고    scopus 로고
    • The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis
    • Maxwell PH, Wiesener MS, Chang GW, et al. The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis. Nature. 1999;339:271-275.
    • (1999) Nature , vol.339 , pp. 271-275
    • Maxwell, P.H.1    Wiesener, M.S.2    Chang, G.W.3
  • 15
    • 0032493368 scopus 로고    scopus 로고
    • 2-dependent degradation domain via the ubiquitin-proteasome pathway
    • 2-dependent degradation domain via the ubiquitin-proteasome pathway. Proc Natl Acad Sci U S A. 1998;95:7987-7992.
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 7987-7992
    • Huang, L.E.1    Gu, J.2    Schau, M.3
  • 16
    • 0036469038 scopus 로고    scopus 로고
    • Asparagine hydroxylation of the HIF-transactivation domain a hypoxic switch
    • Lando D, Peet DJ, Whelan DA, et al. Asparagine hydroxylation of the HIF-transactivation domain a hypoxic switch. Science. 2002;295:858-861.
    • (2002) Science , vol.295 , pp. 858-861
    • Lando, D.1    Peet, D.J.2    Whelan, D.A.3
  • 17
    • 4644275138 scopus 로고    scopus 로고
    • HIF-1: The knows and unknows of hypoxia sensing
    • Zagorska A, Dulak J. HIF-1: the knows and unknows of hypoxia sensing. Acta Biochim Pol. 2004;51:563-585.
    • (2004) Acta Biochim Pol , vol.51 , pp. 563-585
    • Zagorska, A.1    Dulak, J.2
  • 18
    • 0028068606 scopus 로고
    • Transcriptional regulation of genes encoding glycolytic enzymes by hypoxia-inducible factor 1
    • Semenza GL, Roth PH, Fang HM, et al. Transcriptional regulation of genes encoding glycolytic enzymes by hypoxia-inducible factor 1. J Biol Chem. 1994;269:23757-23763.
    • (1994) J Biol Chem , vol.269 , pp. 23757-23763
    • Semenza, G.L.1    Roth, P.H.2    Fang, H.M.3
  • 19
    • 0029761644 scopus 로고    scopus 로고
    • Activation of vascular endothelial growth factor gene transcription by hypoxia-inducible factor 1
    • Forsythe JA, Jiang BH, Iyer NV, et al. Activation of vascular endothelial growth factor gene transcription by hypoxia-inducible factor 1. Mol Cell Biol. 1996;16:4604-4613.
    • (1996) Mol Cell Biol , vol.16 , pp. 4604-4613
    • Forsythe, J.A.1    Jiang, B.H.2    Iyer, N.V.3
  • 20
    • 0029944965 scopus 로고    scopus 로고
    • Dimerization, DNA binding, and transactivation properties of hypoxia-inducible factor 1
    • Jiang BH, Rue E, Wang GL, et al. Dimerization, DNA binding, and transactivation properties of hypoxia-inducible factor 1. J Biol Chem. 1996;271:17771-17778.
    • (1996) J Biol Chem , vol.271 , pp. 17771-17778
    • Jiang, B.H.1    Rue, E.2    Wang, G.L.3
  • 21
    • 0035884701 scopus 로고    scopus 로고
    • HIF-1-dependent regulation of hypoxic induction of the cell death factors BNIP3 and NIX in human tumors
    • Sowter HM, Ratcliffe PJ, Watson P, et al. HIF-1-dependent regulation of hypoxic induction of the cell death factors BNIP3 and NIX in human tumors. Cancer Res. 2001;61:6669-6673.
    • (2001) Cancer Res , vol.61 , pp. 6669-6673
    • Sowter, H.M.1    Ratcliffe, P.J.2    Watson, P.3
  • 22
    • 0037414180 scopus 로고    scopus 로고
    • YC-1: A potential anticancer drug targeting hypoxia-inducible factor-1
    • Yeo EJ, Chun YS, Cho YS, et al. YC-1: a potential anticancer drug targeting hypoxia-inducible factor-1. J Natl Cancer Inst. 2003;95:516-525.
    • (2003) J Natl Cancer Inst , vol.95 , pp. 516-525
    • Yeo, E.J.1    Chun, Y.S.2    Cho, Y.S.3
  • 23
    • 0032734962 scopus 로고    scopus 로고
    • Release of nitric oxide from endothelial cells stimulated by YC-1, an activator of soluble guanylate cyclase
    • Wohlfart P, Malinski T, Ruetten H, et al. Release of nitric oxide from endothelial cells stimulated by YC-1, an activator of soluble guanylate cyclase. Br J Pharmacol. 1999;128:1316-1322.
    • (1999) Br J Pharmacol , vol.128 , pp. 1316-1322
    • Wohlfart, P.1    Malinski, T.2    Ruetten, H.3
  • 24
    • 0037297175 scopus 로고    scopus 로고
    • Regulation of vascular endothelial growth factor synthesis by nitric oxide: Facts and controversies
    • Dulak J, Jozkowicz A. Regulation of vascular endothelial growth factor synthesis by nitric oxide: facts and controversies. Antioxid Redox Signal. 2003;5:123-132.
    • (2003) Antioxid Redox Signal , vol.5 , pp. 123-132
    • Dulak, J.1    Jozkowicz, A.2
  • 25
    • 0032560504 scopus 로고    scopus 로고
    • Inhibition of hypoxia-inducible factor 1 activity by nitric oxide donors in hypoxia
    • Sogawa K, Numayama-Tsuruta K, Ema M, et al. Inhibition of hypoxia-inducible factor 1 activity by nitric oxide donors in hypoxia. Proc Natl Acad Sci USA. 1998;95:7368-7373.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 7368-7373
    • Sogawa, K.1    Numayama-Tsuruta, K.2    Ema, M.3
  • 26
    • 8044253996 scopus 로고    scopus 로고
    • Structural and functional analysis of hypoxia-inducible factor 1
    • Semenaz GL, Agani F, Booth G, et al. Structural and functional analysis of hypoxia-inducible factor 1. Kidney Int. 1997;51:553-555.
    • (1997) Kidney Int , vol.51 , pp. 553-555
    • Semenaz, G.L.1    Agani, F.2    Booth, G.3
  • 27
    • 0035418621 scopus 로고    scopus 로고
    • Constitutive expression of hypoxia-inducible factor-1α renders pancreatic cancer cells resistant to apoptosis induced by hypoxia and nutrient deprivation
    • Akakura N, Kobayashi M, Horiuchi I, et al. Constitutive expression of hypoxia-inducible factor-1α renders pancreatic cancer cells resistant to apoptosis induced by hypoxia and nutrient deprivation. Cancer Res. 2001;61:6548-6554.
    • (2001) Cancer Res , vol.61 , pp. 6548-6554
    • Akakura, N.1    Kobayashi, M.2    Horiuchi, I.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.