Distinct polyfunctional CD4 + T cell responses to BCG, ESAT-6 and CFP-10 in tuberculous pleurisy

Tuberculosis

Volumn 92, Issue 1, 2012, Pages 63-71

  Li, Li ^a   Qiao, Dan ^a   Li, Qin ^a   Zhang, Xianlan ^b   Lao, Suihua ^b   Wu, Changyou ^a  

^a SUN YAT SEN UNIVERSITY   (China)

^b Chest Hospital of Guangzhou   (China)

Author keywords

CFP 10; ESAT 6; Polyfunctional CD4 + T cells; Tuberculous pleurisy

Indexed keywords

BCG VACCINE; CD27 ANTIGEN; CD45RA ANTIGEN; CHEMOKINE RECEPTOR CCR7; CULTURE FILTRATE PROTEIN 10; EARLY SECRETORY ANTIGENIC TARGET 6; GAMMA INTERFERON; INTERLEUKIN 2; L SELECTIN; TUMOR NECROSIS FACTOR ALPHA;

ADOLESCENT; ADULT; AGED; ARTICLE; CD4 LYMPHOCYTE COUNT; CD4+ T LYMPHOCYTE; CELLULAR IMMUNITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; FEMALE; HUMAN; HUMAN CELL; MAJOR CLINICAL STUDY; MALE; PERIPHERAL BLOOD MONONUCLEAR CELL; PHENOTYPE; PLEURA FLUID; PRIORITY JOURNAL; TH1 CELL; TUBERCULOUS PLEURISY;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; ANTIGENS, BACTERIAL; BACTERIAL PROTEINS; CD4-POSITIVE T-LYMPHOCYTES; CYTOKINES; FEMALE; HUMANS; LYMPHOCYTE ACTIVATION; MALE; MIDDLE AGED; MYCOBACTERIUM BOVIS; MYCOBACTERIUM TUBERCULOSIS; TUBERCULOSIS, PLEURAL; YOUNG ADULT;

EID: 84856418231     PISSN: 14729792     EISSN: 1873281X     Source Type: Journal    
DOI: 10.1016/j.tube.2011.11.004     Document Type: Article

References (46)

1. S.H. Kaufmann, S.T. Cole, V. Mizrahi, E. Rubin, and C. Nathan Mycobacterium tuberculosis and the host response J Exp Med 201 2005 1693 1697 (Pubitemid 41002887)
2. E.L. Corbett, C.J. Watt, N. Walker, D. Maher, B.G. Williams, M.C. Raviglione, and C. Dye The growing burden of tuberculosis: global trends and interactions with the HIV epidemic Arch Intern Med 163 2003 1009 1021 (Pubitemid 36548927)
3. S.H. Kaufmann Tuberculosis: back on the immunologists' agenda Immunity 24 2006 351 357
4. A.S. Mustafa Development of new vaccines and diagnostic reagents against tuberculosis Mol Immunol 39 2002 113 119 (Pubitemid 35245389)
5. A. Soysal, K.A. Millington, M. Bakir, D. Dosanjh, Y. Aslan, J.J. Deeks, S. Efe, I. Staveley, K. Ewer, and A. Lalvani Effect of BCG vaccination on risk of Mycobacterium tuberculosis infection in children with household tuberculosis contact: a prospective community-based study Lancet 366 2005 1443 1451 (Pubitemid 41483810)
6. D. Young, and C. Dye The development and impact of tuberculosis vaccines Cell 124 2006 683 687 (Pubitemid 43261442)
7. S.H. Kaufmann Recent findings in immunology give tuberculosis vaccines a new boost Trends Immunol 26 2005 660 667 (Pubitemid 41628199)
8. A.A. Pathan, K.A. Wilkinson, P. Klenerman, H. McShane, R.N. Davidson, G. Pasvol, A.V. Hill, and A. Lalvani Direct ex vivo analysis of antigen-specific IFN-gamma-secreting CD4 T cells in Mycobacterium tuberculosis-infected individuals: associations with clinical disease state and effect of treatment J Immunol 167 2001 5217 5225 (Pubitemid 33009758)
9. A. Lalvani, P. Nagvenkar, Z. Udwadia, A.A. Pathan, K.A. Wilkinson, J.S. Shastri, K. Ewer, A.V. Hill, A. Mehta, and C. Rodrigues Enumeration of T cells specific for RD1-encoded antigens suggests a high prevalence of latent Mycobacterium tuberculosis infection in healthy urban Indians J Infect Dis 183 2001 469 477 (Pubitemid 32105605)
10. H. Shams, P. Klucar, S.E. Weis, A. Lalvani, P.K. Moonan, H. Safi, B. Wizel, K. Ewer, G.T. Nepom, D.M. Lewinsohn, P. Andersen, and P.F. Barnes Characterization of a Mycobacterium tuberculosis peptide that is recognized by human CD4+ and CD8+ T cells in the context of multiple HLA alleles J Immunol 173 2004 1966 1977 (Pubitemid 38971633)
11. T. Ulrichs, M.E. Munk, H. Mollenkopf, S. Behr-Perst, R. Colangeli, M.L. Gennaro, and S.H. Kaufmann Differential T cell responses to Mycobacterium tuberculosis ESAT6 in tuberculosis patients and healthy donors Eur J Immunol 28 1998 3949 3958 (Pubitemid 28558625)
12. J.C. Delgado, A. Baena, S. Thim, and A.E. Goldfeld Aspartic acid homozygosity at codon 57 of HLA-DQ beta is associated with susceptibility to pulmonary tuberculosis in Cambodia J Immunol 176 2006 1090 1097 (Pubitemid 43099710)
13. A.S. Mustafa, F.A. Shaban, R. Al-Attiyah, A.T. Abal, A.M. El-Shamy, P. Andersen, and F. Oftung Human Th1 cell lines recognize the Mycobacterium tuberculosis ESAT-6 antigen and its peptides in association with frequently expressed HLA class II molecules Scand J Immunol 57 2003 125 134 (Pubitemid 36232879)
14. L. Aaron, D. Saadoun, I. Calatroni, O. Launay, N. Mémain, V. Vincent, G. Marchal, B. Dupont, O. Bouchaud, D. Valeyre, and O. Lortholary Tuberculosis in HIV-infected patients: a comprehensive review Clin Microbiol Infect 10 2004 388 398 (Pubitemid 38714564)
15. A.M. Elliott, W.S. Hodsdon, J. Kyosiimire, M.A. Quigley, J.S. Nakiyingi, P.B. Namujju, C. Watera, N. French, C.F. Gilks, H.M. Dockrell, and J.A. Whitworth Cytokine responses and progression to active tuberculosis in HIV-1-infected Ugandans: a prospective study Trans R Soc Trop Med Hyg 98 2004 660 670 (Pubitemid 40029118)
16. J.L. Flynn, J. Chan, K.J. Triebold, D.K. Dalton, T.A. Stewart, and B.R. Bloom An essential role for interferon gamma in resistance to Mycobacterium tuberculosis infection J Exp Med 178 1993 2249 2254 (Pubitemid 23344886)
17. D.A. Lammas, E. De Heer, J.D. Edgar, V. Novelli, A. Ben-Smith, R. Baretto, P. Drysdale, J. Binch, C. MacLennan, D.S. Kumararatne, S. Panchalingam, T.H. Ottenhoff, J.L. Casanova, and J.F. Emile Heterogeneity in the granulomatous response to mycobacterial infection in patients with defined genetic mutations in the interleukin 12-dependent interferon-gamma production pathway Int J Exp Pathol 83 2002 1 20 (Pubitemid 34638943)
18. R. Kamijo, J. Le, D. Shapiro, E.A. Havell, S. Huang, M. Aguet, M. Bosland, and J. Vilcek Mice that lack the interferon-gamma receptor have profoundly altered responses to infection with Bacillus Calmette-Guerin and subsequent challenge with lipopolysaccharide J Exp Med 178 1993 1435 1440 (Pubitemid 23277375)
19. E.M. Agger, and P. Andersen Tuberculosis subunit vaccine development: on the role of interferon-gamma Vaccine 19 2001 2298 2302 (Pubitemid 32234231)
20. T.M. Doherty, and P. Andersen Vaccines for tuberculosis: novel concepts and recent progress Clin Microbiol Rev 18 2005 687 702 (Pubitemid 41504511)
21. O.Y. Saliu, C. Sofer, D.S. Stein, S.K. Schwander, and R.S. Wallis Tumor-necrosis-factor blockers: differential effects on mycobacterial immunity J Infect Dis 194 2006 486 492 (Pubitemid 44162660)
22. S. Stenger Immunological control of tuberculosis: role of tumour necrosis factor and more Ann Rheum Dis 64 2005 v24 v28
23. C. Bouneaud, Z. Garcia, P. Kourilsky, and C. Pannetier Lineage relationships, homeostasis, and recall capacities of central- and effector-memory CD8 T cells in vivo J Exp Med 201 2005 579 590 (Pubitemid 40289548)
24. F. Sallusto, D. Lenig, R. Forster, M. Lipp, and A. Lanzavecchia Two subsets of memory T lymphocytes with distinct homing potentials and effector functions Nature 401 1999 708 712
25. D.R. Roach, A.G. Bean, C. Demangel, M.P. France, H. Briscoe, and W.J. Britton TNF regulates chemokine induction essential for cell recruitment, granuloma formation, and clearance of mycobacterial infection J Immunol 168 2002 4620 4627 (Pubitemid 34441368)
26. P.A. Darrah, D.T. Patel, P.M. De Luca, R.W. Lindsay, D.F. Davey, B.J. Flynn, S.T. Hoff, P. Andersen, S.G. Reed, S.L. Morris, M. Roederer, and R.A. Seder Multifunctional TH1 cells define a correlate of vaccine-mediated protection against Leishmania major Nat Med 13 2007 843 850 (Pubitemid 47038186)
27. N.E. Beveridge, D.A. Price, J.P. Casazza, A.A. Pathan, C.R. Sander, T.E. Asher, D.R. Ambrozak, M.L. Precopio, P. Scheinberg, N.C. Alder, M. Roederer, R.A. Koup, D.C. Douek, A.V. Hill, and H. McShane Immunisation with BCG and recombinant MVA85A induces long-lasting, polyfunctional Mycobacterium tuberculosis-specific CD4+ memory T lymphocyte populations Eur J Immunol 37 2007 3089 3100 (Pubitemid 350131288)
28. C.L. Day, N. Mkhwanazi, S. Reddy, Z. Mncube, M. van der Stok, P. Klenerman, and B.D. Walker Detection of polyfunctional Mycobacterium tuberculosis-specific T cells and association with viral load in HIV-1-infected persons J Infect Dis 197 2008 990 999 (Pubitemid 351590027)
29. J. Patiala Initial tuberculous pleuritis in the Finnish armed forces in 1939-1945 with special reference to eventual postpleuritic tuberculosis Acta Tuberc Scand Suppl 36 1954 1 57
30. W.H. Roper, and J.J. Waring Primary serofibrinous pleural effusion in military personnel Am Rev Tuberc 71 1955 616 634
31. M.C. Souza, C. Penido, M.F. Costa, and M.G. Henriques Mechanisms of T-lymphocyte accumulation during experimental pleural infection induced by Mycobacterium bovis BCG Infect Immun 76 2008 5686 5693
32. F. Budak, E.K. Uzaslan, S. Cangur, G. Goral, and H.B. Oral Increased pleural soluble fas ligand (sFasL) levels in tuberculosis pleurisy and its relation with T-helper type 1 cytokines Lung 186 2008 337 343
33. J. Nemeth, H.M. Winkler, R.H. Zwick, R. Rumetshofer, P. Schenk, O.C. Burghuber, W. Graninger, M. Ramharter, and S. Winkler Recruitment of Mycobacterium tuberculosis specific CD4+ T cells to the site of infection for diagnosis of active tuberculosis J Intern Med 265 2009 163 168
34. F. Sallusto, J. Geginat, and A. Lanzavecchia Central memory and effector memory T cell subsets: function, generation, and maintenance Annu Rev Immunol 22 2004 745 763 (Pubitemid 38680440)
35. K.M. Huster, M. Koffler, C. Stemberger, M. Schiemann, H. Wagner, and D.H. Busch Unidirectional development of CD8+ central memory T cells into protective Listeria-specific effector memory T cells Eur J Immunol 36 2006 1453 1464 (Pubitemid 43942135)
36. R.D. Fritsch, X. Shen, G.P. Sims, K.S. Hathcock, R.J. Hodes, and P.E. Lipsky Stepwise differentiation of CD4 memory T cells defined by expression of CCR7 and CD27 J Immunol 175 2005 6489 6497 (Pubitemid 41598891)
37. A.P. Soares, T.J. Scriba, S. Joseph, R. Harbacheuski, R.A. Murray, S.J. Gelderbloem, A. Hawkridge, G.D. Hussey, H. Maecker, G. Kaplan, and W.A. Hanekom Bacillus Calmette-Guerin vaccination of human newborns induces T cells with complex cytokine and phenotypic profiles J Immunol 180 2008 3569 3577
38. M. Losi, A. Bossink, L. Codecasa, C. Jafari, M. Ernst, S. Thijsen, D. Cirillo, M. Ferrarese, U. Greinert, L.M. Fabbri, L. Richeldi, and C. Lange Use of a T-cell interferon-gamma release assay for the diagnosis of tuberculous pleurisy Eur Respir J 30 2007 1173 1179 (Pubitemid 351194766)
39. P.F. Barnes, S.D. Mistry, C.L. Cooper, C. Pirmez, T.H. Rea, and R.L. Modlin Compartmentalization of a CD4+ T lymphocyte subpopulation in tuberculous pleuritis J Immunol 142 1989 1114 1119 (Pubitemid 19067479)
40. A. Harari, F. Vallelian, P.R. Meylan, and G. Pantaleo Functional heterogeneity of memory CD4 T cell responses in different conditions of antigen exposure and persistence J Immunol 174 2005 1037 1045 (Pubitemid 40094300)
41. K.A. Millington, J.A. Innes, S. Hackforth, T.S. Hinks, J.J. Deeks, D.P. Dosanjh, V. Guyot-Revol, R. Gunatheesan, P. Klenerman, and A. Lalvani Dynamic relationship between IFN-gamma and IL-2 profile of Mycobacterium tuberculosis-specific T cells and antigen load J Immunol 178 2007 5217 5226 (Pubitemid 46595306)
42. T.J. Scriba, M. Tameris, N. Mansoor, E. Smit, L. van der Merwe, F. Isaacs, A. Keyser, S. Moyo, N. Brittain, A. Lawrie, S. Gelderbloem, A. Veldsman, M. Hatherill, A. Hawkridge, A.V. Hill, G.D. Hussey, H. Mahomed, H. McShane, and W.A. Hanekom Modified vaccinia Ankara-expressing Ag85A, a novel tuberculosis vaccine, is safe in adolescents and children, and induces polyfunctional CD4+ T cells Eur J Immunol 40 2010 279 290
43. C. Aagaard, T.T. Hoang, A. Izzo, R. Billeskov, J. Troudt, K. Arnett, A. Keyser, T. Elvang, P. Andersen, and J. Dietrich Protection and polyfunctional T cells induced by Ag85B-TB10.4/IC31 against Mycobacterium tuberculosis is highly dependent on the antigen dose PLoS One 4 2009 e5930
44. C.S. Aagaard, T.T. Hoang, C. Vingsbo-Lundberg, J. Dietrich, and P. Andersen Quality and vaccine efficacy of CD4+ T cell responses directed to dominant and subdominant epitopes in ESAT-6 from Mycobacterium tuberculosis J Immunol 183 2009 2659 2668
45. T.J. Scriba, B. Kalsdorf, D.A. Abrahams, F. Isaacs, J. Hofmeister, G. Black, H.Y. Hassan, R.J. Wilkinson, G. Walzl, S.J. Gelderbloem, H. Mahomed, G.D. Hussey, and W.A. Hanekom Distinct, specific IL-17- and IL-22-producing CD4+ T cell subsets contribute to the human anti-mycobacterial immune response J Immunol 180 2008 1962 1970
46. E.K. Forbes, C. Sander, E.O. Ronan, H. McShane, A.V. Hill, P.C. Beverley, and E.Z. Tchilian Multifunctional, high-level cytokine-producing Th1 cells in the lung, but not spleen, correlate with protection against Mycobacterium tuberculosis aerosol challenge in mice J Immunol 181 2008 4955 4964