Inter-organ proteomic analysis reveals insights into the molecular mechanisms underlying the anti-diabetic effects of cis-9, trans-11-conjugated linoleic acid in ob/ob mice

Proteomics

Volumn 12, Issue 3, 2012, Pages 461-476

  Rungapamestry, Vanessa ^a,b   Mcmonagle, Jolene ^b   Reynolds, Clare ^b   Rucklidge, Garry ^a   Reid, Martin ^a   Duncan, Gary ^a   Ross, Karen ^a   Horgan, Graham ^a   Toomey, Sinead ^b   Moloney, Aidan P ^c   de Roos, Baukje ^a   Roche, Helen M ^b  

^a ROWETT RESEARCH INSTITUTE   (United Kingdom)

^b UNIVERSITY COLLEGE DUBLIN   (Ireland)

^c ANIMAL AND GRASSLAND RESEARCH AND INNOVATION CENTRE   (Ireland)

Author keywords

Cellular stress; Cis 9 trans 11 CLA; Inflammation; Insulin sensitivity; Systems biology

Indexed keywords

ADIPONECTIN; CONJUGATED LINOLEIC ACID; FATTY ACID; INSULIN; INTERLEUKIN 6; MONOCYTE CHEMOTACTIC PROTEIN 1; TRIACYLGLYCEROL;

ACTIN FILAMENT; ADIPOSE TISSUE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARBOHYDRATE METABOLISM; CELL STRESS; CONTROLLED STUDY; DIET SUPPLEMENTATION; ENDOPLASMIC RETICULUM STRESS; ENERGY METABOLISM; FOOD INTAKE; GLUCOSE BLOOD LEVEL; GLUCOSE TRANSPORT; INFLAMMATION; INSULIN BLOOD LEVEL; INSULIN SENSITIVITY; LIVER; MALE; MEMBRANE TRANSPORT; METABOLIC SYNDROME X; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; NUTRITIONAL ASSESSMENT; OXIDATION REDUCTION POTENTIAL; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEOMICS; SKELETAL MUSCLE; WEIGHT GAIN;

ADIPONECTIN; ADIPOSE TISSUE; ANIMALS; BLOOD GLUCOSE; FATTY ACIDS, NONESTERIFIED; GENE EXPRESSION; HYPOGLYCEMIC AGENTS; INSULIN; INSULIN RESISTANCE; INTERLEUKIN-6; LINOLEIC ACIDS, CONJUGATED; LIVER; MALE; MICE; MICE, INBRED C57BL; MUSCLE, SKELETAL; OBESITY; TRIGLYCERIDES;

BOS; MUS;

EID: 84856413427     PISSN: 16159853     EISSN: 16159861     Source Type: Journal    
DOI: 10.1002/pmic.201100312     Document Type: Article

References (44)

1. Olefsky, J. M., Glass, C. K., Macrophages, inflammation, and insulin resistance. Annu. Rev. Physiol. 2010, 72, 219-246.
2. Banni, S., Conjugated linoleic acid metabolism. Curr. Opin. Lipidol. 2002, 13, 261-266.
3. Banni, S., Petroni, A., Blasevich, M., Carta, G. et al., Conjugated linoleic acids (CLA) as precursors of a distinct family of PUFA. Lipids 2004, 39, 1143-1146.
4. Churruca, I., Fernandez-Quintela, A., Portillo, M. P., Conjugated linoleic acid isomers: differences in metabolism and biological effects. Biofactors 2009, 35, 105-111.
5. Reynolds, C. M., Roche, H. M., Conjugated linoleic acid and inflammatory cell signalling. Prostaglandins Leukot. Essent. Fatty Acids 2010, 82, 199-204.
6. de Roos, B., Rucklidge, G., Reid, M., Ross, K. et al., Divergent mechanisms of cis9, trans11-and trans10, cis12-conjugated linoleic acid affecting insulin resistance and inflammation in apolipoprotein E knockout mice: a proteomics approach. FASEB J. 2005, 19, 1746-1748.
7. Moloney, F., Toomey, S., Noone, E., Nugent, A. et al., Antidiabetic effects of cis-9, trans-11-conjugated linoleic acid may be mediated via anti-inflammatory effects in white adipose tissue. Diabetes 2007, 56, 574-582.
8. Toomey, S., McMonagle, J., Roche, H. M., Conjugated linoleic acid: a functional nutrient in the different pathophysiological components of the metabolic syndrome? Curr. Opin. Clin. Nutr. Metab. Care 2006, 9, 740-747.
9. Scollan, N., Hocquette, J., Nuernberg, K., Dannenberger, D. et al., Innovations in beef production systems that enhance the nutritional and health value of beef lipids and their relationship with meat quality. Meat Sci. 2006, 74, 17-33.
10. Tricon, S., Yaqoob, P., Conjugated linoleic acid and human health: a critical evaluation of the evidence. Curr. Opin. Clin. Nutr. Metab. Care 2006, 9, 105-110.
11. Mir, P. S., McAllister, T. A., Scott, S., Aalhus, J. et al., Conjugated linoleic acid-enriched beef production. Am. J. Clin. Nutr. 2004, 79, 1207S-1211S.
12. He, M. L., Mir, P. S., Okine, E. K., Napadajlo, H., Effect of conjugated linoleic acids from beef or industrial hydrogenation on growth and adipose tissue characteristics of rats. Nutr. Metab. (Lond). 2009, 6, 19.
13. Reynolds, C. M., Draper, E., Keogh, B., Rahman, A. et al., A conjugated linoleic acid-enriched beef diet attenuates lipopolysaccharide-induced inflammation in mice in part through PPARgamma-mediated suppression of toll-like receptor 4. J. Nutr. 2009, 139, 2351-2357.
14. Matthews, D. R., Hosker, J. P., Rudenski, A. S., Naylor, B. A. et al., Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 1985, 28, 412-419.
15. Perseghin, G., Caumo, A., Caloni, M., Testolin, G. et al., Incorporation of the fasting plasma FFA concentration into QUICKI improves its association with insulin sensitivity in nonobese individuals. J. Clin. Endocrinol. Metab. 2001, 86, 4776-4781.
16. de Roos, B., Rungapamestry, V., Ross, K., Rucklidge, G. et al., Attenuation of inflammation and cellular stress-related pathways maintains insulin sensitivity in obese type I interleukin-1 receptor knockout mice on a high-fat diet. Proteomics 2009, 9, 3244-3256.
17. de Roos, B., Duivenvoorden, I., Rucklidge, G., Reid, M. et al., Response of apolipoprotein E*3-Leiden transgenic mice to dietary fatty acids: combining liver proteomics with physiological data. FASEB J. 2005, 19, 813-815.
18. Arbones-Mainar, J. M., Ross, K., Rucklidge, G. J., Reid, M. et al., Extra virgin olive oils increase hepatic fat accumulation and hepatic antioxidant protein levels in APOE-/- mice. J. Proteome. Res. 2007, 6, 4041-4054.
19. Kramer, J. K. G., Zhou, J., Conjugated linoleic acid and octadecenoic acid: extraction and isolation of lipids. Eur. J. Lipid Sci. Technol. 2001, 103, 594-599.
20. Park, Y., Albright, K. J., Liu, W., Storkson, J. M. et al., Effect of conjugated linoleic acid on body composition in mice. Lipids 1997, 32, 853-858.
21. McGillicuddy, F. C., Harford, K. A., Reynolds, C. M., Oliver, E. et al., Lack of interleukin-1 receptor I (IL-1RI) protects mice from high-fat diet-induced adipose tissue inflammation coincident with improved glucose homeostasis. Diabetes 2011, 60, 1688-1698.
22. Hotamisligil, G. S., Inflammation and metabolic disorders. Nature 2006, 444, 860-867.
23. Fatehi-Hassanabad, Z., Chan, C. B., Furman, B. L., Reactive oxygen species and endothelial function in diabetes. Eur. J. Pharmacol. 2010, 636, 8-17.
24. Raisanen, S. R., Lehenkari, P., Tasanen, M., Rahkila, P. et al., Carbonic anhydrase III protects cells from hydrogen peroxide-induced apoptosis. FASEB J. 1999, 13, 513-522.
25. Moynihan, J. B., Ennis, S., Acetazolamide-insensitive carbonic anhydrase activities in liver and tonic skeletal muscle of adult male rats with streptozotocin-induced diabetes mellitus. Biochem. J. 1990, 272, 553-556.
26. Hotamisligil, G. S., Endoplasmic reticulum stress and the inflammatory basis of metabolic disease. Cell 2010, 140, 900-917.
27. Malhotra, J. D., Kaufman, R. J., Endoplasmic reticulum stress and oxidative stress: a vicious cycle or a double-edged sword? Antioxid. Redox. Signal. 2007, 9, 2277-2293.
28. Papp, S., Fadel, M. P., Opas, M., Dissecting focal adhesions in cells differentially expressing calreticulin: a microscopy study. Biol. Cell 2007, 99, 389-402.
29. Hultqvist, M., Olsson, L. M., Gelderman, K. A., Holmdahl, R., The protective role of ROS in autoimmune disease. Trends Immunol. 2009, 30, 201-208.
30. Lim, J. W., Kim, K. H., Kim, H., NF-kappaB p65 regulates nuclear translocation of Ku70 via degradation of heat shock cognate protein 70 in pancreatic acinar AR42J cells. Int. J. Biochem. Cell Biol. 2008, 40, 2065-2077.
31. Wang, Y., Kinzie, E., Berger, F. G., Lim, S. K. et al., Haptoglobin, an inflammation-inducible plasma protein. Redox. Rep. 2001, 6, 379-385.
32. Chiellini, C., Bertacca, A., Novelli, S. E., Gorgun, C. Z. et al., Obesity modulates the expression of haptoglobin in the white adipose tissue via TNFα. J. Cell Physiol. 2002, 190, 251-258.
33. Faye, A., Ramey, G., Foretz, M., Vaulont, S., Haptoglobin is degraded by iron in C57BL/6mice: a possible link with endoplasmic reticulum stress. Blood Cells Mol. Dis. 2007, 39, 229-237.
34. Wang, C. H., Wang, C. C., Wei, Y. H., Mitochondrial dysfunction in insulin insensitivity: implication of mitochondrial role in type 2 diabetes. Ann. NY Acad. Sci. 2010, 1201, 157-165.
35. Chen, H. S., Shan, Y. X., Yang, T. L., Lin, H. D. et al., Insulin deficiency downregulated heat shock protein 60 and IGF-1 receptor signaling in diabetic myocardium. Diabetes 2005, 54, 175-181.
36. Zhang, S. J., Sandstrom, M. E., Lanner, J. T., Thorell, A. et al., Activation of aconitase in mouse fast-twitch skeletal muscle during contraction-mediated oxidative stress. Am. J. Physiol. Cell Physiol. 2007, 293, C1154-C1159.
37. Jun, H. S., Hwang, K., Kim, Y., Park, T., High-fat diet alters PP2A, TC10, and CIP4 expression in visceral adipose tissue of rats. Obesity 2008, 16, 1226-1231.
38. Hojlund, K., Poulsen, M., Staehr, P., Brusgaard, K. et al., Effect of insulin on protein phosphatase 2A expression in muscle in type 2 diabetes. Eur. J. Clin. Invest. 2002, 32, 918-923.
39. Kray, A. E., Carter, R. S., Pennington, K. N., Gomez, R. J. et al., Positive regulation of IkappaB kinase signaling by protein serine/threonine phosphatase 2A. J. Biol. Chem. 2005, 280, 35974-35982.
40. Guilherme, A., Soriano, N. A., Bose, S., Holik, J. et al., EHD2 and the novel EH domain binding protein EHBP1 couple endocytosis to the actin cytoskeleton. J. Biol. Chem. 2004, 279, 10593-10605.
41. Usui, I., Imamura, T., Huang, J., Satoh, H. et al., Cdc42 is a Rho GTPase family member that can mediate insulin signaling to glucose transport in 3T3-L1 adipocytes. J. Biol. Chem. 2003, 278, 13765-13774.
42. Greenberg, C. C., Jurczak, M. J., Danos, A. M., Brady, M. J., Glycogen branches out: new perspectives on the role of glycogen metabolism in the integration of metabolic pathways. Am. J. Physiol. Endocrinol. Metab. 2006, 291, E1-E8.
43. Bickel, P. E., Metabolic fuel selection: the importance of being flexible. J. Clin. Invest. 2004, 114, 1547-1549.
44. Kotani, K., Peroni, O. D., Minokoshi, Y., Boss, O. et al., GLUT4 glucose transporter deficiency increases hepatic lipid production and peripheral lipid utilization. J. Clin. Invest. 2004, 114, 1666-1675.