Engineering and Functionalization of the Disulfide-Constrained Miniprotein Min-23 as a Scaffold for Diagnostic Application

ChemMedChem

Volumn 7, Issue 2, 2012, Pages 237-247

  Zoller, Frederic ^a,b   Schwaebel, Thimon ^b   Markert, Annette ^a   Haberkorn, Uwe ^a,b   Mier, Walter ^b  

^a GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^b UNIVERSITY HOSPITAL HEIDELBERG   (Germany)

Author keywords

Diagnostic imaging; Miniproteins; Peptide chemistry; Positron emission tomography; Scaffolds

Indexed keywords

DISULFIDE; MINIPROTEIN 23; SCAFFOLD PROTEIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; DIAGNOSTIC IMAGING; DISULFIDE BOND; HUMAN; IN VITRO STUDY; IN VIVO STUDY; ISOTOPE LABELING; NONHUMAN; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN ENGINEERING; PROTEIN FOLDING; PROTEIN FUNCTION; PROTEIN SYNTHESIS; RAT; SOLID PHASE SYNTHESIS;

AMINO ACID SEQUENCE; ANIMALS; CONTRAST MEDIA; DISULFIDES; HUMANS; INDIUM RADIOISOTOPES; ISOTOPE LABELING; MICE; MOLECULAR SEQUENCE DATA; NEOPLASMS; PEPTIDES; POSITRON-EMISSION TOMOGRAPHY; PROTEIN ENGINEERING; PROTEIN FOLDING; TISSUE DISTRIBUTION;

EID: 84856406821     PISSN: 18607179     EISSN: 18607187     Source Type: Journal    
DOI: 10.1002/cmdc.201100497     Document Type: Article

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