Preliminary evaluation of 177Lu-labeled knottin peptides for integrin receptor-targeted radionuclide therapy

European Journal of Nuclear Medicine and Molecular Imaging

Volumn 38, Issue 4, 2011, Pages 613-622

  Jiang, Lei ^a,b   Miao, Zheng ^b   Kimura, Richard H ^c   Liu, Hongguang ^b   Cochran, Jennifer R ^c   Culter, Cathy S ^d   Bao, Ande ^e   Li, Peiyong ^a   Cheng, Zhen ^b  

^a SHANGHAI JIAO TONG UNIVERSITY   (China)

^b STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c STANFORD CANCER INSTITUTE   (United States)

^d UNIVERSITY OF MISSOURI   (United States)

^e UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

Author keywords

177Lu; Cystine knot peptide; Integrin; Radionuclide therapy

Indexed keywords

1,4,7,10 TETRAAZACYCLODODECANE 1,4,7,10 TETRAACETIC ACID; INTEGRIN RECEPTOR; KNOTTIN; LUTETIUM 177; PEPTIDE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DOSIMETRY; DRUG DISTRIBUTION; GLIOMA; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ISOTOPE LABELING; MALE; MOUSE; NONHUMAN; PROTEIN STABILITY; PROTEIN TRANSPORT; RADIATION ABSORPTION; RECEPTOR BINDING; XENOGRAFT;

ADULT; AMINO ACID SEQUENCE; ANIMALS; CELL LINE, TUMOR; CELL TRANSFORMATION, NEOPLASTIC; CYSTINE-KNOT MINIPROTEINS; GENE EXPRESSION REGULATION, NEOPLASTIC; HETEROCYCLIC COMPOUNDS, 1-RING; HUMANS; INTEGRINS; LUTETIUM; MALE; MICE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PLATELET MEMBRANE GLYCOPROTEINS; PROTEIN CONFORMATION; RADIATION DOSAGE; RADIOCHEMISTRY; RADIOISOTOPES; RADIOTHERAPY;

EID: 79953718744     PISSN: 16197070     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00259-010-1684-x     Document Type: Article

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