-
1
-
-
77950373635
-
Leptin therapy in insulin-deficient type I diabetes.
-
Wang MY, Chen L, Clark GO et al. Leptin therapy in insulin-deficient type I diabetes. Proc Natl Acad Sci U S A 2010: 107: 4813-4819.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 4813-4819
-
-
Wang, M.Y.1
Chen, L.2
Clark, G.O.3
-
2
-
-
0028139089
-
Positional cloning of the mouse obese gene and its human homologue.
-
Zhang Y, Proenca R, Maffei M, Barone M, Leopold L, Friedman JM. Positional cloning of the mouse obese gene and its human homologue. Nature 1994: 372: 425-432.
-
(1994)
Nature
, vol.372
, pp. 425-432
-
-
Zhang, Y.1
Proenca, R.2
Maffei, M.3
Barone, M.4
Leopold, L.5
Friedman, J.M.6
-
3
-
-
0032558725
-
Leptin and the regulation of body weight in mammals.
-
Friedman JM, Halaas JL. Leptin and the regulation of body weight in mammals. Nature 1998: 395: 763-770.
-
(1998)
Nature
, vol.395
, pp. 763-770
-
-
Friedman, J.M.1
Halaas, J.L.2
-
4
-
-
45549103125
-
Partial leptin deficiency favors diet-induced obesity and related metabolic disorders in mice.
-
Begriche K, Letteron P, Abbey-Toby A et al. Partial leptin deficiency favors diet-induced obesity and related metabolic disorders in mice. Am J Physiol Endocrinol Metab 2008: 294: E939-E951.
-
(2008)
Am J Physiol Endocrinol Metab
, vol.294
-
-
Begriche, K.1
Letteron, P.2
Abbey-Toby, A.3
-
5
-
-
0033517284
-
Leptin reverses insulin resistance and diabetes mellitus in mice with congenital lipodystrophy.
-
Shimomura I, Hammer RE, Ikemoto S, Brown MS, Goldstein JL. Leptin reverses insulin resistance and diabetes mellitus in mice with congenital lipodystrophy. Nature 1999: 401: 73-76.
-
(1999)
Nature
, vol.401
, pp. 73-76
-
-
Shimomura, I.1
Hammer, R.E.2
Ikemoto, S.3
Brown, M.S.4
Goldstein, J.L.5
-
6
-
-
0037067570
-
Role for stearoyl-CoA desaturase-1 in leptin-mediated weight loss.
-
Cohen P, Miyazaki M, Socci ND et al. Role for stearoyl-CoA desaturase-1 in leptin-mediated weight loss. Science 2002: 297: 240-243.
-
(2002)
Science
, vol.297
, pp. 240-243
-
-
Cohen, P.1
Miyazaki, M.2
Socci, N.D.3
-
7
-
-
0037326196
-
Peroxisome proliferator-activated receptor-gamma coactivator 1 alpha (PGC-1 alpha): transcriptional coactivator and metabolic regulator.
-
Puigserver P, Spiegelman BM. Peroxisome proliferator-activated receptor-gamma coactivator 1 alpha (PGC-1 alpha): transcriptional coactivator and metabolic regulator. Endocr Rev 2003: 24: 78-90.
-
(2003)
Endocr Rev
, vol.24
, pp. 78-90
-
-
Puigserver, P.1
Spiegelman, B.M.2
-
8
-
-
0037122766
-
Leptin stimulates fatty-acid oxidation by activating AMP-activated protein kinase.
-
Minokoshi Y, Kim YB, Peroni OD et al. Leptin stimulates fatty-acid oxidation by activating AMP-activated protein kinase. Nature 2002: 415: 339-343.
-
(2002)
Nature
, vol.415
, pp. 339-343
-
-
Minokoshi, Y.1
Kim, Y.B.2
Peroni, O.D.3
-
9
-
-
11144357287
-
Site and mechanism of leptin action in a rodent form of congenital lipodystrophy.
-
Asilmaz E, Cohen P, Miyazaki M et al. Site and mechanism of leptin action in a rodent form of congenital lipodystrophy. J Clin Invest 2004: 113: 414-424.
-
(2004)
J Clin Invest
, vol.113
, pp. 414-424
-
-
Asilmaz, E.1
Cohen, P.2
Miyazaki, M.3
-
10
-
-
0034776770
-
Selective deletion of leptin receptor in neurons leads to obesity.
-
Cohen P, Zhao C, Cai X et al. Selective deletion of leptin receptor in neurons leads to obesity. J Clin Invest 2001: 108: 1113-1121.
-
(2001)
J Clin Invest
, vol.108
, pp. 1113-1121
-
-
Cohen, P.1
Zhao, C.2
Cai, X.3
-
11
-
-
79551600048
-
Glucagon receptor knockout prevents insulin-deficient type 1 diabetes in mice.
-
Lee Y, Wang MY, Du XQ, Charron MJ, Unger RH. Glucagon receptor knockout prevents insulin-deficient type 1 diabetes in mice. Diabetes 2011: 60: 391-397.
-
(2011)
Diabetes
, vol.60
, pp. 391-397
-
-
Lee, Y.1
Wang, M.Y.2
Du, X.Q.3
Charron, M.J.4
Unger, R.H.5
-
12
-
-
77954980506
-
Glucagon deficiency reduces hepatic glucose production and improves glucose tolerance in adult mice.
-
Hancock AS, Du A, Liu J, Miller M, May CL. Glucagon deficiency reduces hepatic glucose production and improves glucose tolerance in adult mice. Mol Endocrinol 2010: 24: 1605-1614.
-
(2010)
Mol Endocrinol
, vol.24
, pp. 1605-1614
-
-
Hancock, A.S.1
Du, A.2
Liu, J.3
Miller, M.4
May, C.L.5
-
13
-
-
4344690525
-
Recombinant human leptin in women with hypothalamic amenorrhea.
-
Welt CK, Chan JL, Bullen J et al. Recombinant human leptin in women with hypothalamic amenorrhea. N Engl J Med 2004: 351: 987-997.
-
(2004)
N Engl J Med
, vol.351
, pp. 987-997
-
-
Welt, C.K.1
Chan, J.L.2
Bullen, J.3
-
14
-
-
0037148928
-
Leptin-replacement therapy for lipodystrophy.
-
Oral EA, Simha V, Ruiz E et al. Leptin-replacement therapy for lipodystrophy. N Engl J Med 2002: 346: 570-578.
-
(2002)
N Engl J Med
, vol.346
, pp. 570-578
-
-
Oral, E.A.1
Simha, V.2
Ruiz, E.3
-
15
-
-
0036800760
-
Beneficial effects of leptin on obesity, T cell hyporesponsiveness, and neuroendocrine/metabolic dysfunction of human congenital leptin deficiency.
-
Farooqi IS, Matarese G, Lord GM et al. Beneficial effects of leptin on obesity, T cell hyporesponsiveness, and neuroendocrine/metabolic dysfunction of human congenital leptin deficiency. J Clin Invest 2002: 110: 1093-1103.
-
(2002)
J Clin Invest
, vol.110
, pp. 1093-1103
-
-
Farooqi, I.S.1
Matarese, G.2
Lord, G.M.3
-
16
-
-
69749086148
-
Enhanced weight loss with pramlintide/metreleptin: an integrated neurohormonal approach to obesity pharmacotherapy.
-
Ravussin E, Smith SR, Mitchell JA et al. Enhanced weight loss with pramlintide/metreleptin: an integrated neurohormonal approach to obesity pharmacotherapy. Obesity (Silver Spring) 2009: 17: 1736-1743.
-
(2009)
Obesity (Silver Spring)
, vol.17
, pp. 1736-1743
-
-
Ravussin, E.1
Smith, S.R.2
Mitchell, J.A.3
-
17
-
-
0037636366
-
The physiology of cellular liporegulation.
-
Unger RH. The physiology of cellular liporegulation. Annu Rev Physiol 2003: 65: 333-347.
-
(2003)
Annu Rev Physiol
, vol.65
, pp. 333-347
-
-
Unger, R.H.1
-
18
-
-
77953954942
-
Rationale for leptin-replacement therapy for severe lipodystrophy.
-
Oral EA, Chan JL. Rationale for leptin-replacement therapy for severe lipodystrophy. Endocr Pract 2010: 16: 324-333.
-
(2010)
Endocr Pract
, vol.16
, pp. 324-333
-
-
Oral, E.A.1
Chan, J.L.2
-
19
-
-
38149012112
-
Type 1 diabetes associated with acquired generalized lipodystrophy and insulin resistance: the effect of long-term leptin therapy.
-
Park JY, Chong AY, Cochran EK et al. Type 1 diabetes associated with acquired generalized lipodystrophy and insulin resistance: the effect of long-term leptin therapy. J Clin Endocrinol Metab 2008: 93: 26-31.
-
(2008)
J Clin Endocrinol Metab
, vol.93
, pp. 26-31
-
-
Park, J.Y.1
Chong, A.Y.2
Cochran, E.K.3
-
20
-
-
1942441000
-
Efficacy of recombinant methionyl human leptin therapy for the extreme insulin resistance of the Rabson-Mendenhall syndrome.
-
Cochran E, Young JR, Sebring N, DePaoli A, Oral EA, Gorden P. Efficacy of recombinant methionyl human leptin therapy for the extreme insulin resistance of the Rabson-Mendenhall syndrome. J Clin Endocrinol Metab 2004: 89: 1548-1554.
-
(2004)
J Clin Endocrinol Metab
, vol.89
, pp. 1548-1554
-
-
Cochran, E.1
Young, J.R.2
Sebring, N.3
DePaoli, A.4
Oral, E.A.5
Gorden, P.6
|