The phosphatidyl inositol 3 kinase-glycogen synthase kinase 3β pathway mediates bilobalide-induced reduction in amyloid β-peptide

Neurochemical Research

Volumn 37, Issue 2, 2012, Pages 298-306

  Shi, Chun ^a   Zheng, Dong Dan ^b   Wu, Feng Ming ^c   Liu, Jun ^b   Xu, Jie ^c  

^a GUANGZHOU MEDICAL UNIVERSITY   (China)

^b SUN YAT SEN UNIVERSITY   (China)

^c SUN YAT SEN UNIVERSITY   (China)

Author keywords

Amyloid precursor protein (APP); Bilobalide (BB); Cathepsin B; Glycogen synthase kinase 3 (GSK3 ); Phosphatidyl inositol 3 kinase (PI3K)

Indexed keywords

AMYLOID PRECURSOR PROTEIN; BETA SECRETASE 1; BILOBALIDE; CATHEPSIN B; GAMMA SECRETASE; GLYCOGEN SYNTHASE KINASE; GLYCOGEN SYNTHASE KINASE 3BETA; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN CELL; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; ENZYME ACTIVITY; ENZYME INHIBITION; IN VITRO STUDY; IN VIVO STUDY; INTRACELLULAR SIGNALING; MOUSE; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN METABOLISM; SENESCENCE ACCELERATED MOUSE;

AMYLOID BETA-PEPTIDES; ANIMALS; CELL LINE; CYCLOPENTANES; FURANS; GINKGOLIDES; GLYCOGEN SYNTHASE KINASE 3; MICE; PHOSPHATIDYLINOSITOL 3-KINASE; SIGNAL TRANSDUCTION;

GINKGO BILOBA; MUS;

EID: 84856393256     PISSN: 03643190     EISSN: 15736903     Source Type: Journal    
DOI: 10.1007/s11064-011-0612-1     Document Type: Article

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