The PI3K-Akt pathway regulates calpain 6 expression, proliferation, and apoptosis

Cellular Signalling

Volumn 23, Issue 5, 2011, Pages 827-836

  Liu, Yonglei ^a   Mei, Chuanzhong ^a   Sun, Lidong ^a   Li, Xin ^a   Liu, Mingzhu ^a   Wang, Liying ^a,b,c   Li, Zengxia ^a,b,c   Yin, Peng ^a   Zhao, Chao ^a   Shi, Yinghong ^a   Qiu, Shuangjian ^a   Fan, Jia ^a   Zha, Xiliang ^a,b,c  

^a FUDAN UNIVERSITY   (China)

^b BEIJING HOSPITAL   (China)

^c BEIJING UNIVERSITY OF POSTS AND TELECOMMUNICATIONS   (China)

Author keywords

Akt; AP1; Calpain 6; FoxD3; Oct 1; PI3K

Indexed keywords

CALPAIN; CALPAIN 6; DNA FRAGMENT; GLYCOGEN SYNTHASE KINASE 3BETA; OCTAMER TRANSCRIPTION FACTOR 1; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR AP 1; TRANSCRIPTION FACTOR FOXD3; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; BINDING SITE; CANCER CELL; CELL PROLIFERATION; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVITY; ENZYME STABILITY; GENE DELETION; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION;

ANIMALS; APOPTOSIS; BINDING SITES; CALPAIN; CELL LINE; CELL PROLIFERATION; FIBROBLASTS; FORKHEAD TRANSCRIPTION FACTORS; HUMANS; MICE; OCTAMER TRANSCRIPTION FACTOR-1; PHOSPHATIDYLINOSITOL 3-KINASES; PROMOTER REGIONS, GENETIC; PROTO-ONCOGENE PROTEINS C-AKT; REPRESSOR PROTEINS; RNA INTERFERENCE; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTOR AP-1;

EID: 79951855699     PISSN: 08986568     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cellsig.2011.01.005     Document Type: Article

References (35)

1. Croall D.E., Ersfeld K. Genome Biol. 2007, 8:218.
2. Srivastava A.K., McMillan S., Jermak C., Shomaker M., Copeland-Yates S.A., Sossey-Alaoui K., Mumm S., Schlessinger D., Nagaraja R. Genomics 1999, 58:188.
3. Dear T.N., Boehm T. Mech. Dev. 1999, 89:201.
4. Tonami K., Kurihara Y., Aburatani H., Uchijima Y., Asano T., Kurihara H. Mol. Cell. Biol. 2007, 27:2548.
5. Rho S.B., Byun H.J., Park S.Y., Chun T. Cancer Lett. 2008, 271:306.
6. Lee S.J., Choi Y.L., Lee E.J., Kim B.G., Bae D.S., Ahn G.H., Lee J.H. Int. J. Gynecol. Cancer 2007, 17:248.
7. Lee S.J., Kim B.G., Choi Y.L., Lee J.W. Oncol. Rep. 2008, 19:859.
8. Matena K., Boehm T., Dear N. Genomics 1998, 48:117.
9. Chin Y.R., Toker A. Cell. Signal. 2009, 21:470.
10. Liu P., Cheng H., Roberts T.M., Zhao J.J. Nat. Rev. Drug Discov. 2009, 8:627.
11. Manning B.D., Cantley L.C. Cell 2007, 129:1261.
12. Carnero A. Curr. Pharm. Des. 2010, 16:34.
13. Bader A.G., Kang S., Zhao L., Vogt P.K. Nat. Rev. Cancer 2005, 5:921.
14. Toker A., Yoeli-Lerner M. Cancer Res. 2006, 66:3963.
15. Hodgkinson C.P., Sale E.M., Sale G.J. Biochemistry 2002, 41:10351.
16. Héron-Milhavet L., Franckhauser C., Rana V., Berthenet C., Fisher D., Hemmings B.A., Fernandez A., Lamb N.J. Mol. Cell. Biol. 2006, 26:8267.
17. Gao D., Inuzuka H., Tseng A., Chin R.Y., Toker A., Wei W. Nat. Cell Biol. 2009, 11:397.
18. Moro L., Arbini A.A., Yao J.L., di Sant'Agnese P.A., Marra E., Greco M. Cell Death Differ. 2009, 16:571.
19. Gonzalez E., McGraw T.E. Proc. Natl Acad. Sci. USA 2009, 106:7004.
20. Yap T.A., Garrett M.D., Walton M.I., Raynaud F., de Bono J.S., Workman P. Curr. Opin. Pharmacol. 2008, 8:393.
21. Fulda S. Curr. Cancer Drug Targets 2009, 9:729.
22. Sabatini D.M. Nat. Rev. Cancer 2006, 6:729.
23. Beaulieu J.M., Gainetdinov R.R., Caron M.G. Annu. Rev. Pharmacol. Toxicol. 2009, 49:327.
24. Liang J., Slingerland J.M. Cell Cycle 2003, 2:339.
25. Shaulian E. Cell. Signal. 2010, 22:894.
26. Eferl R., Wagner E.F. Nat. Rev. Cancer 2003, 3:859.
27. Sutton J., Costa R., Klug M., Field L., Xu D., Largaespada D., Fletcher C., Jenkins N., Copeland N., Klemsz M., Hromas R. J. Biol. Chem. 1996, 271:23126.
28. Kakizawa T., Miyamoto T., Ichikawa K., Kaneko A., Suzuki S., Hara M., Nagasawa T., Takeda T., Mori J., Kumagai M., Hashizume K. J. Biol. Chem. 1999, 274:19103.
29. Kakizawa T., Miyamoto T., Ichikawa K., Takeda T., Suzuki S., Mori J., Kumagai M., Yamashita K., Hashizume K. J. Biol. Chem. 2001, 276:9720.
30. Ivanov V.N., Krasilnikov M., Ronai Z. J. Biol. Chem. 2002, 277:4932.
31. George Paul A., Sharma-Walia N., Kerur N., White C., Chandran B. Cancer Res. 2010, 70:3697.
32. Lee M.Y., Lim H.W., Lee S.H., Han H.J. Stem Cells 2009, 27:1858.
33. Cakir M., Grossman A.B. Expert Opin. Ther. Targets 2009, 13:1121.
34. Brauer P.M., Tyner A.L. Cell Cycle 2009, 8:2728.
35. Dear N., Matena K., Vingron M., Boehm T. Genomics 1997, 45:175.