[ 125I]SD-7015 reveals fine modalities of CB 1 cannabinoid receptor density in the prefrontal cortex during progression of Alzheimer's disease

Neurochemistry International

Volumn 60, Issue 3, 2012, Pages 286-291

  Farkas, Szabolcs ^a   Nagy, Katalin ^a   Palkovits, Miklós ^b   Kovács, Gábor G ^c   Jia, Zhisheng ^d   Donohue, Sean ^e   Pike, Vic ^e   Halldin, Christer ^d   Máthé, Domokos ^f,g   Harkany, Tibor ^d   Gulyás, Balázs ^d   Csiba, László ^a  

^a UNIVERSITY OF DEBRECEN   (Hungary)

^b SEMMELWEIS UNIVERSITY OF MEDICINE   (Hungary)

^c MEDICAL UNIVERSITY OF VIENNA   (Austria)

^d KAROLINSKA INSTITUTE   (Sweden)

^e NATIONAL INSTITUTE OF MENTAL HEALTH   (United States)

^f SEMMELWEIS UNIVERSITY   (Hungary)

^g CROmed Ltd   (Hungary)

Author keywords

125I SD7015; Alzheimer's disease; Biomarker; Braak classification; CB 1R; Endocannabinoid system; Human brain autoradiography; Molecular imaging

Indexed keywords

CANNABINOID 1 RECEPTOR; CANNABINOID 1 RECEPTOR AGONIST; IODINE 125; RIMONABANT; SD 7015; UNCLASSIFIED DRUG; 4 CYANO 1 (2 IODOPHENYL) 5 (4 METHOXYPHENYL) N (PIPERIDIN 1 YL) 1H PYRAZOLE 3 CARBOXAMIDE; 4-CYANO-1-(2-IODOPHENYL)-5-(4-METHOXYPHENYL)-N-(PIPERIDIN-1-YL)-1H-PYRAZOLE-3-CARBOXAMIDE; DIAGNOSTIC AGENT; PYRAZOLE DERIVATIVE; RADIOPHARMACEUTICAL AGENT;

ALZHEIMER DISEASE; ARTICLE; AUTORADIOGRAPHY; CONTROLLED STUDY; DISEASE COURSE; HUMAN; HUMAN TISSUE; LIGAND BINDING; PATHOLOGY; PREFRONTAL CORTEX; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR DENSITY; STAGING; UPREGULATION; AGED; AGING; CALIBRATION; DRUG EFFECT; FEMALE; HEALTH CARE FACILITY; MALE; METABOLISM; MIDDLE AGED; PHYSIOLOGY; SCINTISCANNING;

AGED; AGED, 80 AND OVER; AGING; ALZHEIMER DISEASE; AUTORADIOGRAPHY; CALIBRATION; DISEASE PROGRESSION; FEMALE; HUMANS; MALE; MIDDLE AGED; PREFRONTAL CORTEX; PYRAZOLES; RADIOPHARMACEUTICALS; RECEPTOR, CANNABINOID, CB1; TISSUE BANKS;

EID: 84856359746     PISSN: 01970186     EISSN: 18729754     Source Type: Journal    
DOI: 10.1016/j.neuint.2011.11.004     Document Type: Article

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