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Volumn 47, Issue 10, 2006, Pages 1689-1696

11C-JHU75528: A radiotracer for PET imaging of CB1 cannabinoid receptors

Author keywords

11C JHU75528; Cannabinoid receptor; PET

Indexed keywords

8 CHLORO 2,3,4,5 TETRAHYDRO 3 METHYL 5 PHENYL 1H 3 BENZAZEPIN 7 OL HYDROGEN MALEATE; [4 CYANO 1 (2,4 DICHLOROPHENYL) 5 (4 METHOXYPHENYL) N (PIPERIDIN 1 YL) 1H PYRAZOLE 3 CARBOXAMIDE] C 11; CANNABINOID 1 RECEPTOR; CYTISINE; JHU 75528; KETANSERIN; NALOXONE; NALTRINDOLE; RADIOLIGAND; RADIOPHARMACEUTICAL AGENT; RIMONABANT; SPIPERONE; UNCLASSIFIED DRUG; 4 CYANO 1 (2,4 DICHLOROPHENYL) 5 (4 METHOXYPHENYL) N (PIPERIDIN 1 YL) 1H PYRAZOLE 3 CARBOXAMIDE; 4-CYANO-1-(2,4-DICHLOROPHENYL)-5-(4-METHOXYPHENYL)-N-(PIPERIDIN-1-YL)-1H-PYRAZOLE-3-CARBOXAMIDE; CARBON; LIGAND; PIPERIDINE DERIVATIVE; PYRAZOLE DERIVATIVE;

EID: 34547486580     PISSN: 01615505     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (102)

References (40)
  • 1
    • 18444376760 scopus 로고    scopus 로고
    • International Union of Pharmacology. XXVII. classification of cannabinoid receptors
    • Howlett AC, Barth F, Bonner TI, et al. International Union of Pharmacology. XXVII. classification of cannabinoid receptors. Pharmacol Rev. 2002;54:161-202.
    • (2002) Pharmacol Rev , vol.54 , pp. 161-202
    • Howlett, A.C.1    Barth, F.2    Bonner, T.I.3
  • 2
    • 33644804271 scopus 로고    scopus 로고
    • The therapeutic potential of drugs that target cannabinoid receptors or modulate the tissue levels or actions of endocannabinoids
    • Pertwee RG. The therapeutic potential of drugs that target cannabinoid receptors or modulate the tissue levels or actions of endocannabinoids. AAPS J. 2005;7:E625-E654.
    • (2005) AAPS J , vol.7
    • Pertwee, R.G.1
  • 3
    • 14844296375 scopus 로고    scopus 로고
    • Cannabinoid receptors and their relationships with neuropsychiatric disorders
    • Gambi F, De Berardis D, Sepede G, et al. Cannabinoid receptors and their relationships with neuropsychiatric disorders. Int J Immunopathol Pharmacol. 2005;18:15-19.
    • (2005) Int J Immunopathol Pharmacol , vol.18 , pp. 15-19
    • Gambi, F.1    De Berardis, D.2    Sepede, G.3
  • 4
    • 26044473986 scopus 로고    scopus 로고
    • A role for cannabinoid CB1 receptors in mood and anxiety disorders
    • Witkin JM, Tzavara ET, Nomikos GG. A role for cannabinoid CB1 receptors in mood and anxiety disorders. Behav Pharmacol. 2005;16:315-331.
    • (2005) Behav Pharmacol , vol.16 , pp. 315-331
    • Witkin, J.M.1    Tzavara, E.T.2    Nomikos, G.G.3
  • 5
    • 22844434552 scopus 로고    scopus 로고
    • Cannabinoid CB1 receptors control conditioned drug seeking
    • De Vries TJ, Schoffelmeer AN. Cannabinoid CB1 receptors control conditioned drug seeking. Trends Pharmacol Sci. 2005;26:420-426.
    • (2005) Trends Pharmacol Sci , vol.26 , pp. 420-426
    • De Vries, T.J.1    Schoffelmeer, A.N.2
  • 6
    • 19544370717 scopus 로고    scopus 로고
    • Control of the reinforcing effects of nicotine by associated environmental stimuli in animals and humans
    • Le Foll B, Goldberg SR. Control of the reinforcing effects of nicotine by associated environmental stimuli in animals and humans. Trends Pharmacol Sci. 2005;26:287-293.
    • (2005) Trends Pharmacol Sci , vol.26 , pp. 287-293
    • Le Foll, B.1    Goldberg, S.R.2
  • 7
    • 15444363610 scopus 로고    scopus 로고
    • Cannabinoids and the regulation of ingestive behaviour
    • Vickers SP, Kennett GA. Cannabinoids and the regulation of ingestive behaviour. Curr Drug Targets. 2005;6:215-223.
    • (2005) Curr Drug Targets , vol.6 , pp. 215-223
    • Vickers, S.P.1    Kennett, G.A.2
  • 8
    • 0028129936 scopus 로고
    • SR141716A, a potent and selective antagonist of the brain cannabinoid receptor
    • Rinaldi-Carmona M, Barth F, Heaulme M, et al. SR141716A, a potent and selective antagonist of the brain cannabinoid receptor. FEBS Lett. 1994;350:240-244.
    • (1994) FEBS Lett , vol.350 , pp. 240-244
    • Rinaldi-Carmona, M.1    Barth, F.2    Heaulme, M.3
  • 9
    • 17144382751 scopus 로고    scopus 로고
    • Effects of the cannabinoid-1 receptor blocker rimonabant on weight reduction and cardiovascular risk factors in overweight patients: 1-year experience from the RIO-Europe study
    • Van Gaal LF, Rissanen AM, Scheen AJ, Ziegler O, Rossner S. Effects of the cannabinoid-1 receptor blocker rimonabant on weight reduction and cardiovascular risk factors in overweight patients: 1-year experience from the RIO-Europe study. Lancet. 2005;365:1389-1397.
    • (2005) Lancet , vol.365 , pp. 1389-1397
    • Van Gaal, L.F.1    Rissanen, A.M.2    Scheen, A.J.3    Ziegler, O.4    Rossner, S.5
  • 10
    • 2942556913 scopus 로고    scopus 로고
    • Clinical trials update and cumulative meta-analyses from the American College of Cardiology: WATCH, SCD-HeFT, DINAMIT, CASINO, INSPIRE, STRATUS-US, RIO-lipids and cardiac resynchronisation therapy in heart failure
    • Cleland JG, Ghosh J, Freemantle N, et al. Clinical trials update and cumulative meta-analyses from the American College of Cardiology: WATCH, SCD-HeFT, DINAMIT, CASINO, INSPIRE, STRATUS-US, RIO-lipids and cardiac resynchronisation therapy in heart failure. Eur J Heart Fail. 2004;6:501-508.
    • (2004) Eur J Heart Fail , vol.6 , pp. 501-508
    • Cleland, J.G.1    Ghosh, J.2    Freemantle, N.3
  • 12
    • 0033058682 scopus 로고    scopus 로고
    • 18F] SR144385: A selective radioligand for positron emission tomographic studies of brain cannabinoid receptors
    • 18F] SR144385: a selective radioligand for positron emission tomographic studies of brain cannabinoid receptors. J Labelled Compds Radiopharm. 1999;42:589-596.
    • (1999) J Labelled Compds Radiopharm , vol.42 , pp. 589-596
    • Mathews, W.B.1    Ravert, H.T.2    Musachio, J.L.3
  • 13
    • 0034353125 scopus 로고    scopus 로고
    • 18F] SR147963: Selective radioligands for positron emission tomographic studies of brain cannabinoid receptors
    • 18F] SR147963: selective radioligands for positron emission tomographic studies of brain cannabinoid receptors. Nucl Med Biol. 2000;27:757-762.
    • (2000) Nucl Med Biol , vol.27 , pp. 757-762
    • Mathews, W.B.1    Scheffel, U.2    Finley, P.3
  • 14
    • 0036701658 scopus 로고    scopus 로고
    • Carbon-11 labeled radioligands for imaging brain cannabinoid receptors
    • Mathews WB, Scheffel U, Rauseo PA, et al. Carbon-11 labeled radioligands for imaging brain cannabinoid receptors. Nucl Med Biol. 2002;29:671-677.
    • (2002) Nucl Med Biol , vol.29 , pp. 671-677
    • Mathews, W.B.1    Scheffel, U.2    Rauseo, P.A.3
  • 15
    • 0037434591 scopus 로고    scopus 로고
    • Synthesis, structure-activity relationship, and evaluation of SR141716 analogues: Development of central cannabinoid receptor ligands with lower lipophilicity
    • Katoch-Rouse R, Pavlova OA, Caulder T, Hoffman AF, Mukhin AG, Horti AG. Synthesis, structure-activity relationship, and evaluation of SR141716 analogues: development of central cannabinoid receptor ligands with lower lipophilicity. J Med Chem. 2003;46:642-645.
    • (2003) J Med Chem , vol.46 , pp. 642-645
    • Katoch-Rouse, R.1    Pavlova, O.A.2    Caulder, T.3    Hoffman, A.F.4    Mukhin, A.G.5    Horti, A.G.6
  • 16
    • 0042365056 scopus 로고    scopus 로고
    • Regioselective F-18 radiolabeling of AM694, a CB1 cannabinoid receptor ligand
    • Willis PG, Katoch-Rouse R, Horti AG. Regioselective F-18 radiolabeling of AM694, a CB1 cannabinoid receptor ligand. J Labelled Compds Radiopharm. 2003;46:799-804.
    • (2003) J Labelled Compds Radiopharm , vol.46 , pp. 799-804
    • Willis, P.G.1    Katoch-Rouse, R.2    Horti, A.G.3
  • 17
    • 0037238625 scopus 로고    scopus 로고
    • 18F]fluorination: A PET radiotracer for studying CB1 cannabinoid receptors
    • 18F]fluorination: a PET radiotracer for studying CB1 cannabinoid receptors. J Labelled Compds Radiopharm. 2003;46:93-98.
    • (2003) J Labelled Compds Radiopharm , vol.46 , pp. 93-98
    • Katoch-Rouse, R.1    Horti, A.G.2
  • 18
    • 18944392211 scopus 로고    scopus 로고
    • Development of PET and SPECT radioligands for cannabinoid receptors
    • Makriyannis A, Biegel D, eds, New York, NY: Marcel Dekker, Inc
    • Gatley SJ, Gifford AN, Ding Y-S, et al. Development of PET and SPECT radioligands for cannabinoid receptors. In: Makriyannis A, Biegel D, eds. Drug Discovery Strategies and Methods. New York, NY: Marcel Dekker, Inc.; 2004:129-146.
    • (2004) Drug Discovery Strategies and Methods , pp. 129-146
    • Gatley, S.J.1    Gifford, A.N.2    Ding, Y.-S.3
  • 19
    • 0031972639 scopus 로고    scopus 로고
    • Imaging the brain marijuana receptor: Development of a radioligand that binds to cannabinoid CB1 receptors in vivo
    • Gatley SJ, Lan R, Volkow ND, et al. Imaging the brain marijuana receptor: development of a radioligand that binds to cannabinoid CB1 receptors in vivo. J Neurochem. 1998;70:417-423.
    • (1998) J Neurochem , vol.70 , pp. 417-423
    • Gatley, S.J.1    Lan, R.2    Volkow, N.D.3
  • 20
    • 18944375992 scopus 로고    scopus 로고
    • 18F]AM5144 and related pyrazole compounds
    • 18F]AM5144 and related pyrazole compounds. Nucl Med Biol. 2005;32:361-366.
    • (2005) Nucl Med Biol , vol.32 , pp. 361-366
    • Li, Z.1    Gifford, A.2    Liu, Q.3
  • 21
    • 11144356598 scopus 로고    scopus 로고
    • 9-tetrahydrocannabinol therapy and whole-body scanning for assessment of radiation dose in Tourette patients
    • 9-tetrahydrocannabinol therapy and whole-body scanning for assessment of radiation dose in Tourette patients. Biol Psychiatry. 2004;55:904-915.
    • (2004) Biol Psychiatry , vol.55 , pp. 904-915
    • Berding, G.1    Muller-Vahl, K.2    Schneider, U.3
  • 22
    • 24744436637 scopus 로고    scopus 로고
    • Synthesis and structure-activity relationship of a novel series of aminoalkylindoles with potential for imaging the neuronal cannabinoid receptor by positron emission tomography
    • Willis PG, Pavlova OA, Chefer SI, Vaupel DB, Mukhin AG, Horti AG. Synthesis and structure-activity relationship of a novel series of aminoalkylindoles with potential for imaging the neuronal cannabinoid receptor by positron emission tomography. J Med Chem. 2005;48:5813-5822.
    • (2005) J Med Chem , vol.48 , pp. 5813-5822
    • Willis, P.G.1    Pavlova, O.A.2    Chefer, S.I.3    Vaupel, D.B.4    Mukhin, A.G.5    Horti, A.G.6
  • 23
    • 0344983883 scopus 로고    scopus 로고
    • Relationships between radiotracer properties and image quality in molecular imaging of the brain with positron emission tomography
    • Laruelle M, Slifstein M, Huang Y. Relationships between radiotracer properties and image quality in molecular imaging of the brain with positron emission tomography. Mol Imaging Biol. 2003;5:363-375.
    • (2003) Mol Imaging Biol , vol.5 , pp. 363-375
    • Laruelle, M.1    Slifstein, M.2    Huang, Y.3
  • 24
    • 0344121272 scopus 로고    scopus 로고
    • Determination of lipophilicity and its use as a predictor of blood-brain barrier penetration of molecular imaging agents
    • Waterhouse RN. Determination of lipophilicity and its use as a predictor of blood-brain barrier penetration of molecular imaging agents. Mol Imaging Biol. 2003;5:376-389.
    • (2003) Mol Imaging Biol , vol.5 , pp. 376-389
    • Waterhouse, R.N.1
  • 25
    • 35048860855 scopus 로고    scopus 로고
    • Development of C-11-NIDA-41020: A potential radiotracer for studying cerebral cannabinoid receptors (CB1) by PET
    • Presented at: May 25-28, Turku, Finland
    • Katoch-Rouse R, Chefer SI, Pavlova OA, et al. Development of C-11-NIDA-41020: a potential radiotracer for studying cerebral cannabinoid receptors (CB1) by PET. Presented at: IX Symposium on the Medical Applications of Cyclotrons; May 25-28, 2002; Turku, Finland.
    • (2002) IX Symposium on the Medical Applications of Cyclotrons
    • Katoch-Rouse, R.1    Chefer, S.I.2    Pavlova, O.A.3
  • 26
    • 0141958109 scopus 로고    scopus 로고
    • In silico prediction of blood-brain barrier permeation
    • Clark DE. In silico prediction of blood-brain barrier permeation. Drug Discov Today. 2003;8:927-933.
    • (2003) Drug Discov Today , vol.8 , pp. 927-933
    • Clark, D.E.1
  • 27
    • 0033538481 scopus 로고    scopus 로고
    • Cannabinoid receptor interactions with the antagonists SR141716A and SR144528
    • Shire D, Calandra B, Bouaboula M, et al. Cannabinoid receptor interactions with the antagonists SR141716A and SR144528. Life Sci. 1999;65:627-635.
    • (1999) Life Sci , vol.65 , pp. 627-635
    • Shire, D.1    Calandra, B.2    Bouaboula, M.3
  • 29
    • 0027455623 scopus 로고
    • 18F]fluoro-dopa and positron emission tomography: Error analysis and application to normal subjects
    • 18F]fluoro-dopa and positron emission tomography: error analysis and application to normal subjects. J Cereb Blood Flow Metab. 1993;13:43-56.
    • (1993) J Cereb Blood Flow Metab , vol.13 , pp. 43-56
    • Kuwabara, H.1    Cumming, P.2    Reith, J.3
  • 31
    • 0041335224 scopus 로고    scopus 로고
    • 11C]DASB positron emission tomography studies of the serotonin transporter in human brain
    • 11C]DASB positron emission tomography studies of the serotonin transporter in human brain. J Cereb Blood Flow Metab. 2003;23:1096-1112.
    • (2003) J Cereb Blood Flow Metab , vol.23 , pp. 1096-1112
    • Ichise, M.1    Liow, J.S.2    Lu, J.Q.3
  • 33
    • 0031047273 scopus 로고    scopus 로고
    • Cannabinoid receptors in the human brain: A detailed anatomical and quantitative autoradiographic study in the fetal, neonatal and adult human brain
    • Glass M, Dragunow M, Faull RL. Cannabinoid receptors in the human brain: a detailed anatomical and quantitative autoradiographic study in the fetal, neonatal and adult human brain. Neuroscience. 1997;77:299-318.
    • (1997) Neuroscience , vol.77 , pp. 299-318
    • Glass, M.1    Dragunow, M.2    Faull, R.L.3
  • 35
    • 0141782243 scopus 로고    scopus 로고
    • Demethylation of radiolabelled dextromethorphan in rat microsomes and intact hepatocytes
    • Di Marco A, Yao D, Laufer R. Demethylation of radiolabelled dextromethorphan in rat microsomes and intact hepatocytes. Eur J Biochem. 2003;270:3768-3777.
    • (2003) Eur J Biochem , vol.270 , pp. 3768-3777
    • Di Marco, A.1    Yao, D.2    Laufer, R.3
  • 37
    • 1642523101 scopus 로고    scopus 로고
    • 3H]SR141716A binding to cannabinoid CB1 receptors is increased in the anterior cingulate cortex in schizophrenia
    • 3H]SR141716A binding to cannabinoid CB1 receptors is increased in the anterior cingulate cortex in schizophrenia. Prog Neuropsychopharmacol Biol Psychiatry. 2004;28:355-360.
    • (2004) Prog Neuropsychopharmacol Biol Psychiatry , vol.28 , pp. 355-360
    • Zavitsanou, K.1    Garrick, T.2    Huang, X.F.3
  • 38
    • 12444281775 scopus 로고    scopus 로고
    • New perspectives in the studies on endocannabinoid and cannabis: Cannabinoid receptors and schizophrenia
    • Ujike H, Morita Y. New perspectives in the studies on endocannabinoid and cannabis: cannabinoid receptors and schizophrenia. J Pharmacol Sci. 2004;96:376-381.
    • (2004) J Pharmacol Sci , vol.96 , pp. 376-381
    • Ujike, H.1    Morita, Y.2
  • 39
    • 1542344972 scopus 로고    scopus 로고
    • 35S]GTPgammaS binding in the prefrontal cortex of depressed suicide victims
    • 35S]GTPgammaS binding in the prefrontal cortex of depressed suicide victims. Mol Psychiatry. 2004;9:184-190.
    • (2004) Mol Psychiatry , vol.9 , pp. 184-190
    • Hungund, B.L.1    Vinod, K.Y.2    Kassir, S.A.3
  • 40
    • 14644422174 scopus 로고    scopus 로고
    • Elevated levels of endocannabinoids and CB1 receptor-mediated G-protein signaling in the prefrontal cortex of alcoholic suicide victims
    • Vinod KY, Arango V, Xie S, et al. Elevated levels of endocannabinoids and CB1 receptor-mediated G-protein signaling in the prefrontal cortex of alcoholic suicide victims. Biol Psychiatry. 2005;57:480-486.
    • (2005) Biol Psychiatry , vol.57 , pp. 480-486
    • Vinod, K.Y.1    Arango, V.2    Xie, S.3


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