Imaging and quantitation of cannabinoid CB1 receptors in human and monkey brains using 18F-labeled inverse agonist radioligands

Journal of Nuclear Medicine

Volumn 51, Issue 1, 2010, Pages 112-120

  Terry, Garth E ^a,b   Hirvonen, Jussi ^a   Liow, Jeih San ^a   Zoghbi, Sami S ^a   Gladding, Robert ^a   Tauscher, Johannes T ^c   Schaus, John M ^a,c   Phebus, Lee ^c   Felder, Christian C ^c   Morse, Cheryl L ^a   Donohue, Sean R ^a   Pike, Victor W ^a   Halldin, Christer ^b   Innis, Robert B ^a  

^a NATIONAL INSTITUTE OF MENTAL HEALTH   (United States)

^b KAROLINSKA INSTITUTE   (Sweden)

^c ELI LILLY AND COMPANY   (United States)

Author keywords

Brain imaging neuroimaging; Positron emission tomography

Indexed keywords

CANNABINOID 1 RECEPTOR; RADIOLIGAND; RIMONABANT;

ADULT; ARTICLE; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; DRUG BLOOD LEVEL; FEMALE; HUMAN; HUMAN EXPERIMENT; ISOTOPE LABELING; MALE; MOLECULAR IMAGING; MONKEY; NEUROIMAGING; NONHUMAN; NORMAL HUMAN; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RADIOACTIVITY; RECEPTOR BINDING; TEST RETEST RELIABILITY;

ADULT; ANIMALS; AREA UNDER CURVE; BRAIN; BRAIN CHEMISTRY; FEMALE; FLUORODEOXYGLUCOSE F18; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; ISOTOPE LABELING; MACACA MULATTA; MALE; PLASMA; PYRROLIDINONES; RADIOPHARMACEUTICALS; RECEPTOR, CANNABINOID, CB1; SKULL; YOUNG ADULT;

EID: 75149158928     PISSN: 01615505     EISSN: None     Source Type: Journal    
DOI: 10.2967/jnumed.109.067074     Document Type: Article

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