-
1
-
-
67649797371
-
β-Arrestin-2 mediates anti-apoptotic signaling through regulation of BAD phosphorylation
-
Ahn S., Kim J., Hara M.R., et al. β-Arrestin-2 mediates anti-apoptotic signaling through regulation of BAD phosphorylation. J Biol Chem 2009, 284:8855-8865.
-
(2009)
J Biol Chem
, vol.284
, pp. 8855-8865
-
-
Ahn, S.1
Kim, J.2
Hara, M.R.3
-
2
-
-
4143070533
-
Differential kinetic and spatial patterns of beta-arrestin and G protein-mediated ERK activation by the angiotensin II receptor
-
Ahn S., Shenoy S.K., Wei H., Lefkowitz R.J. Differential kinetic and spatial patterns of beta-arrestin and G protein-mediated ERK activation by the angiotensin II receptor. J Biol Chem 2004, 279:35518-35525.
-
(2004)
J Biol Chem
, vol.279
, pp. 35518-35525
-
-
Ahn, S.1
Shenoy, S.K.2
Wei, H.3
Lefkowitz, R.J.4
-
3
-
-
59449109185
-
Angiotensin II type-1 receptor activation in the adult heart causes blood pressure-independent hypertrophy and cardiac dysfunction
-
Ainscough J.F., Drinkhill M.J., Sedo A., et al. Angiotensin II type-1 receptor activation in the adult heart causes blood pressure-independent hypertrophy and cardiac dysfunction. Cardiovasc Res 2009, 81:592-600.
-
(2009)
Cardiovasc Res
, vol.81
, pp. 592-600
-
-
Ainscough, J.F.1
Drinkhill, M.J.2
Sedo, A.3
-
4
-
-
79951512210
-
Strategies to discover unexpected targets for drugs active at G protein-coupled receptors
-
Allen J.A., Roth B.L. Strategies to discover unexpected targets for drugs active at G protein-coupled receptors. Annu Rev Pharmacol Toxicol 2011, 51:117-144.
-
(2011)
Annu Rev Pharmacol Toxicol
, vol.51
, pp. 117-144
-
-
Allen, J.A.1
Roth, B.L.2
-
5
-
-
79952265050
-
β-Arrestin 1 inhibits the GTPase-activating protein function of ARHGAP21, promoting activation of RhoA following angiotensin II type 1A receptor stimulation
-
Anthony D.F., Sin Y.Y., Vadrevu S., et al. β-Arrestin 1 inhibits the GTPase-activating protein function of ARHGAP21, promoting activation of RhoA following angiotensin II type 1A receptor stimulation. Mol Cell Biol 2011, 31:1066-1075.
-
(2011)
Mol Cell Biol
, vol.31
, pp. 1066-1075
-
-
Anthony, D.F.1
Sin, Y.Y.2
Vadrevu, S.3
-
6
-
-
57249089047
-
Molecular determinants of angiotensin II type 1 receptor functional selectivity
-
Aplin M., Bonde M.M., Hansen J.L. Molecular determinants of angiotensin II type 1 receptor functional selectivity. J Mol Cell Cardiol 2009, 46:15-24.
-
(2009)
J Mol Cell Cardiol
, vol.46
, pp. 15-24
-
-
Aplin, M.1
Bonde, M.M.2
Hansen, J.L.3
-
7
-
-
34247351122
-
The angiotensin type 1 receptor activates extracellular signal-regulated kinases 1 and 2 by G protein-dependent and -independent pathways in cardiac myocytes and Langendorff-perfused hearts
-
Aplin M., Christensen G.L., Schneider M., et al. The angiotensin type 1 receptor activates extracellular signal-regulated kinases 1 and 2 by G protein-dependent and -independent pathways in cardiac myocytes and Langendorff-perfused hearts. Basic Clin Pharmacol Toxicol 2007, 100:289-295.
-
(2007)
Basic Clin Pharmacol Toxicol
, vol.100
, pp. 289-295
-
-
Aplin, M.1
Christensen, G.L.2
Schneider, M.3
-
8
-
-
34247341288
-
Differential extracellular signal-regulated kinases 1 and 2 activation by the angiotensin type 1 receptor supports distinct phenotypes of cardiac myocytes
-
Aplin M., Christensen G.L., Schneider M., et al. Differential extracellular signal-regulated kinases 1 and 2 activation by the angiotensin type 1 receptor supports distinct phenotypes of cardiac myocytes. Basic Clin Pharmacol Toxicol 2007, 100:296-301.
-
(2007)
Basic Clin Pharmacol Toxicol
, vol.100
, pp. 296-301
-
-
Aplin, M.1
Christensen, G.L.2
Schneider, M.3
-
9
-
-
77955893501
-
Long-term survival of cancer patients compared to heart failure and stroke: A systematic review
-
Askoxylakis V., Thieke C., Pleger S.T., et al. Long-term survival of cancer patients compared to heart failure and stroke: A systematic review. BMC Cancer 2010, 10:105.
-
(2010)
BMC Cancer
, vol.10
, pp. 105
-
-
Askoxylakis, V.1
Thieke, C.2
Pleger, S.T.3
-
10
-
-
34447125603
-
Gain-of-function mutant of angiotensin II receptor, type 1A, causes hypertension and cardiovascular fibrosis in mice
-
Billet S., Bardin S., Verp S., et al. Gain-of-function mutant of angiotensin II receptor, type 1A, causes hypertension and cardiovascular fibrosis in mice. J Clin Invest 2007, 117:1914-1925.
-
(2007)
J Clin Invest
, vol.117
, pp. 1914-1925
-
-
Billet, S.1
Bardin, S.2
Verp, S.3
-
11
-
-
0021058380
-
Operational models of pharmacological agonism
-
Black J.W., Leff P. Operational models of pharmacological agonism. Proc R Soc London B Biol Sci 1983, 220:141-162.
-
(1983)
Proc R Soc London B Biol Sci
, vol.220
, pp. 141-162
-
-
Black, J.W.1
Leff, P.2
-
12
-
-
84856343982
-
Cardiorenal actions of TRV120027, a novel, β-arrestin-biased ligand at the angiotensin II type I receptor, in healthy and heart failure canines: A novel therapeutic strategy for acute heart failure
-
Boerrigter G., Lark M.W., Whalen E.J., et al. Cardiorenal actions of TRV120027, a novel, β-arrestin-biased ligand at the angiotensin II type I receptor, in healthy and heart failure canines: A novel therapeutic strategy for acute heart failure. Circ Heart Fail 2011, 4:770-778.
-
(2011)
Circ Heart Fail
, vol.4
, pp. 770-778
-
-
Boerrigter, G.1
Lark, M.W.2
Whalen, E.J.3
-
13
-
-
77954693401
-
Quantitative phosphoproteomics dissection of seven-transmembrane receptor signaling using full and biased agonists
-
Christensen G.L., Kelstrup C.D., Lyngso C., et al. Quantitative phosphoproteomics dissection of seven-transmembrane receptor signaling using full and biased agonists. Mol Cell Proteomics 2010, 9:1540-1553.
-
(2010)
Mol Cell Proteomics
, vol.9
, pp. 1540-1553
-
-
Christensen, G.L.1
Kelstrup, C.D.2
Lyngso, C.3
-
14
-
-
0030613761
-
Switching of the coupling of the beta2-adrenergic receptor to different G proteins by protein kinase A
-
Daaka Y., Luttrell L.M., Lefkowitz R.J. Switching of the coupling of the beta2-adrenergic receptor to different G proteins by protein kinase A. Nature 1997, 390:88-91.
-
(1997)
Nature
, vol.390
, pp. 88-91
-
-
Daaka, Y.1
Luttrell, L.M.2
Lefkowitz, R.J.3
-
15
-
-
27844583473
-
Divergent behavioral roles of angiotensin receptor intracellular signaling cascades
-
Daniels D., Yee D.K., Faulconbridge L.F., Fluharty S.J. Divergent behavioral roles of angiotensin receptor intracellular signaling cascades. Endocrinology 2005, 146:5552-5560.
-
(2005)
Endocrinology
, vol.146
, pp. 5552-5560
-
-
Daniels, D.1
Yee, D.K.2
Faulconbridge, L.F.3
Fluharty, S.J.4
-
16
-
-
44849117014
-
Beta-arrestin-mediated signaling regulates protein synthesis
-
DeWire S.M., Kim J., Whalen E.J., et al. Beta-arrestin-mediated signaling regulates protein synthesis. J Biol Chem 2008, 283:10611-10620.
-
(2008)
J Biol Chem
, vol.283
, pp. 10611-10620
-
-
DeWire, S.M.1
Kim, J.2
Whalen, E.J.3
-
17
-
-
79959783092
-
EGFR trans-activation by urotensin II receptor is mediated by beta-arrestin recruitment and confers cardioprotection in pressure overload-induced cardiac hypertrophy
-
Esposito G., Perrino C., Cannavo A., et al. EGFR trans-activation by urotensin II receptor is mediated by beta-arrestin recruitment and confers cardioprotection in pressure overload-induced cardiac hypertrophy. Basic Res Cardiol 2011, 106:577-589.
-
(2011)
Basic Res Cardiol
, vol.106
, pp. 577-589
-
-
Esposito, G.1
Perrino, C.2
Cannavo, A.3
-
18
-
-
78751538699
-
Quantification of functional selectivity at the human alpha(1A)-adrenoceptor
-
Evans B.A., Broxton N., Merlin J., et al. Quantification of functional selectivity at the human alpha(1A)-adrenoceptor. Mol Pharmacol 2011, 79:298-307.
-
(2011)
Mol Pharmacol
, vol.79
, pp. 298-307
-
-
Evans, B.A.1
Broxton, N.2
Merlin, J.3
-
19
-
-
28844460569
-
A transgenic mouse model of heart failure using inducible Gαq
-
Fan G., Jiang Y.P., Lu Z., et al. A transgenic mouse model of heart failure using inducible Gαq. J Biol Chem 2005, 280:40337-40346.
-
(2005)
J Biol Chem
, vol.280
, pp. 40337-40346
-
-
Fan, G.1
Jiang, Y.P.2
Lu, Z.3
-
21
-
-
0141811657
-
The role of a conserved region of the second intracellular loop in AT1 angiotensin receptor activation and signaling
-
Gaborik Z., Jagadeesh G., Zhang M., et al. The role of a conserved region of the second intracellular loop in AT1 angiotensin receptor activation and signaling. Endocrinology 2003, 144:2220-2228.
-
(2003)
Endocrinology
, vol.144
, pp. 2220-2228
-
-
Gaborik, Z.1
Jagadeesh, G.2
Zhang, M.3
-
22
-
-
33751162165
-
Distinct signaling profiles of beta1 and beta2 adrenergic receptor ligands toward adenylyl cyclase and mitogen-activated protein kinase reveals the pluridimensionality of efficacy
-
Galandrin S., Bouvier M. Distinct signaling profiles of beta1 and beta2 adrenergic receptor ligands toward adenylyl cyclase and mitogen-activated protein kinase reveals the pluridimensionality of efficacy. Mol Pharmacol 2006, 70:1575-1584.
-
(2006)
Mol Pharmacol
, vol.70
, pp. 1575-1584
-
-
Galandrin, S.1
Bouvier, M.2
-
23
-
-
77952373578
-
The angiotensin II type 1 receptor induces membrane blebbing by coupling to Rho A, Rho kinase, and myosin light chain kinase
-
Godin C.M., Ferguson S.S. The angiotensin II type 1 receptor induces membrane blebbing by coupling to Rho A, Rho kinase, and myosin light chain kinase. Mol Pharmacol 2010, 77:903-911.
-
(2010)
Mol Pharmacol
, vol.77
, pp. 903-911
-
-
Godin, C.M.1
Ferguson, S.S.2
-
24
-
-
78149400043
-
Beta-blockers: Focus on mechanism of action. Which beta-blocker, when and why?
-
Gorre F., Vandekerckhove H. Beta-blockers: Focus on mechanism of action. Which beta-blocker, when and why?. Acta Cardiol 2010, 65:565-570.
-
(2010)
Acta Cardiol
, vol.65
, pp. 565-570
-
-
Gorre, F.1
Vandekerckhove, H.2
-
25
-
-
48049099668
-
The human angiotensin AT(1) receptor supports G protein-independent extracellular signal-regulated kinase 1/2 activation and cellular proliferation
-
Hansen J.L., Aplin M., Hansen J.T., et al. The human angiotensin AT(1) receptor supports G protein-independent extracellular signal-regulated kinase 1/2 activation and cellular proliferation. Eur J Pharmacol 2008, 590:255-263.
-
(2008)
Eur J Pharmacol
, vol.590
, pp. 255-263
-
-
Hansen, J.L.1
Aplin, M.2
Hansen, J.T.3
-
26
-
-
36148981452
-
Vascular smooth muscle G(q) signaling is involved in high blood pressure in both induced renal and genetic vascular smooth muscle-derived models of hypertension
-
Harris D.M., Cohn H.I., Pesant S., et al. Vascular smooth muscle G(q) signaling is involved in high blood pressure in both induced renal and genetic vascular smooth muscle-derived models of hypertension. Am J Physiol Heart Circ Physiol 2007, 293:H3072-H3079.
-
(2007)
Am J Physiol Heart Circ Physiol
, vol.293
-
-
Harris, D.M.1
Cohn, H.I.2
Pesant, S.3
-
27
-
-
0036208442
-
Side-chain substitutions within angiotensin II reveal different requirements for signaling, internalization, and phosphorylation of type 1A angiotensin receptors
-
Holloway A.C., Qian H., Pipolo L., et al. Side-chain substitutions within angiotensin II reveal different requirements for signaling, internalization, and phosphorylation of type 1A angiotensin receptors. Mol Pharmacol 2002, 61:768-777.
-
(2002)
Mol Pharmacol
, vol.61
, pp. 768-777
-
-
Holloway, A.C.1
Qian, H.2
Pipolo, L.3
-
28
-
-
15744390934
-
Beta-arrestin 2-dependent angiotensin II type 1A receptor-mediated pathway of chemotaxis
-
Hunton D.L., Barnes W.G., Kim J., et al. Beta-arrestin 2-dependent angiotensin II type 1A receptor-mediated pathway of chemotaxis. Mol Pharmacol 2005, 67:1229-1236.
-
(2005)
Mol Pharmacol
, vol.67
, pp. 1229-1236
-
-
Hunton, D.L.1
Barnes, W.G.2
Kim, J.3
-
29
-
-
65549154913
-
2009 focused update: ACCF/AHA guidelines for the diagnosis and management of heart failure in adults: A report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines: Developed in collaboration with the International Society for Heart and Lung Transplantation
-
Jessup M., Abraham W.T., Casey D.E., et al. 2009 focused update: ACCF/AHA guidelines for the diagnosis and management of heart failure in adults: A report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines: Developed in collaboration with the International Society for Heart and Lung Transplantation. Circulation 2009, 119:1977-2016.
-
(2009)
Circulation
, vol.119
, pp. 1977-2016
-
-
Jessup, M.1
Abraham, W.T.2
Casey, D.E.3
-
30
-
-
69649097791
-
'7TM receptor allostery: Putting numbers to shapeshifting proteins
-
Kenakin T.P. '7TM receptor allostery: Putting numbers to shapeshifting proteins. Trends Pharmacol Sci 2009, 30:460-469.
-
(2009)
Trends Pharmacol Sci
, vol.30
, pp. 460-469
-
-
Kenakin, T.P.1
-
32
-
-
55749084393
-
Beta-blockers alprenolol and carvedilol stimulate beta-arrestin-mediated EGFR transactivation
-
Kim I.M., Tilley D.G., Chen J., et al. Beta-blockers alprenolol and carvedilol stimulate beta-arrestin-mediated EGFR transactivation. Proc Natl Acad Sci USA 2008, 105:14555-14560.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 14555-14560
-
-
Kim, I.M.1
Tilley, D.G.2
Chen, J.3
-
33
-
-
0029957543
-
Mechanisms of beta-adrenergic receptor desensitization: From molecular biology to heart failure
-
Lohse M.J., Engelhardt S., Danner S., Bohm M. Mechanisms of beta-adrenergic receptor desensitization: From molecular biology to heart failure. Basic Res Cardiol 1996, 91(Suppl 2):29-34.
-
(1996)
Basic Res Cardiol
, vol.91
, Issue.SUPPL. 2
, pp. 29-34
-
-
Lohse, M.J.1
Engelhardt, S.2
Danner, S.3
Bohm, M.4
-
34
-
-
77951872871
-
β-Arrestin-dependent activation of Ca(2+)/calmodulin kinase II after β(1)-adrenergic receptor stimulation
-
Mangmool S., Shukla A.K., Rockman H.A. β-Arrestin-dependent activation of Ca(2+)/calmodulin kinase II after β(1)-adrenergic receptor stimulation. J Cell Biol 2010, 189:573-587.
-
(2010)
J Cell Biol
, vol.189
, pp. 573-587
-
-
Mangmool, S.1
Shukla, A.K.2
Rockman, H.A.3
-
35
-
-
77957221089
-
μ-Opioid receptors: Correlation of agonist efficacy for signalling with ability to activate internalization
-
McPherson J., Rivero G., Baptist M., et al. μ-Opioid receptors: Correlation of agonist efficacy for signalling with ability to activate internalization. Mol Pharmacol 2010, 78:756-766.
-
(2010)
Mol Pharmacol
, vol.78
, pp. 756-766
-
-
McPherson, J.1
Rivero, G.2
Baptist, M.3
-
36
-
-
27544458100
-
Influence of heart rate, blood pressure, and beta-blocker dose on outcome and the differences in outcome between carvedilol and metoprolol tartrate in patients with chronic heart failure: Results from the COMET trial
-
Metra M., Torp-Pedersen C., Swedberg K., et al. Influence of heart rate, blood pressure, and beta-blocker dose on outcome and the differences in outcome between carvedilol and metoprolol tartrate in patients with chronic heart failure: Results from the COMET trial. Eur Heart J 2005, 26:2259-2268.
-
(2005)
Eur Heart J
, vol.26
, pp. 2259-2268
-
-
Metra, M.1
Torp-Pedersen, C.2
Swedberg, K.3
-
37
-
-
34848820302
-
β-Arrestin-mediated β1-adrenergic receptor transactivation of the EGFR confers cardioprotection
-
Noma T., Lemaire A., Naga Prasad S.V., et al. β-Arrestin-mediated β1-adrenergic receptor transactivation of the EGFR confers cardioprotection. J Clin Invest 2007, 117:2445-2458.
-
(2007)
J Clin Invest
, vol.117
, pp. 2445-2458
-
-
Noma, T.1
Lemaire, A.2
Naga Prasad, S.V.3
-
38
-
-
3142776467
-
Comparison of carvedilol and metoprolol on clinical outcomes in patients with chronic heart failure in the Carvedilol or Metoprolol European Trial (COMET): Randomised controlled trial
-
Poole-Wilson P.A., Swedberg K., Cleland J.G., et al. Comparison of carvedilol and metoprolol on clinical outcomes in patients with chronic heart failure in the Carvedilol or Metoprolol European Trial (COMET): Randomised controlled trial. Lancet 2003, 362:7-13.
-
(2003)
Lancet
, vol.362
, pp. 7-13
-
-
Poole-Wilson, P.A.1
Swedberg, K.2
Cleland, J.G.3
-
39
-
-
80051979129
-
Quantifying ligand bias at seven-transmembrane receptors
-
Rajagopal S., Ahn S., Rominger D.H., et al. Quantifying ligand bias at seven-transmembrane receptors. Mol Pharmacol 2011, 80:367-377.
-
(2011)
Mol Pharmacol
, vol.80
, pp. 367-377
-
-
Rajagopal, S.1
Ahn, S.2
Rominger, D.H.3
-
40
-
-
0027182438
-
Molecular characterization of angiotensin II-induced hypertrophy of cardiac myocytes and hyperplasia of cardiac fibroblasts: Critical role of the AT1 receptor subtype
-
Sadoshima J., Izumo S. Molecular characterization of angiotensin II-induced hypertrophy of cardiac myocytes and hyperplasia of cardiac fibroblasts: Critical role of the AT1 receptor subtype. Circ Res 1993, 73:413-423.
-
(1993)
Circ Res
, vol.73
, pp. 413-423
-
-
Sadoshima, J.1
Izumo, S.2
-
42
-
-
0037088597
-
AT1 receptor mutant lacking heterotrimeric G protein coupling activates the Src-Ras-ERK pathway without nuclear translocation of ERKs
-
Seta K., Nanamori M., Modrall J.G., et al. AT1 receptor mutant lacking heterotrimeric G protein coupling activates the Src-Ras-ERK pathway without nuclear translocation of ERKs. J Biol Chem 2002, 277:9268-9277.
-
(2002)
J Biol Chem
, vol.277
, pp. 9268-9277
-
-
Seta, K.1
Nanamori, M.2
Modrall, J.G.3
-
44
-
-
0034820506
-
More "malignant" than cancer?. Five-year survival following a first admission for heart failure
-
Stewart S., MacIntyre K., Hole D.J., et al. More "malignant" than cancer?. Five-year survival following a first admission for heart failure. Eur J Heart Fail 2001, 3:315-322.
-
(2001)
Eur J Heart Fail
, vol.3
, pp. 315-322
-
-
Stewart, S.1
MacIntyre, K.2
Hole, D.J.3
-
45
-
-
77953291767
-
Troglitazone stimulates beta-arrestin-dependent cardiomyocyte contractility via the angiotensin II type 1A receptor
-
Tilley D.G., Nguyen A.D., Rockman H.A. Troglitazone stimulates beta-arrestin-dependent cardiomyocyte contractility via the angiotensin II type 1A receptor. Biochem Biophys Res Commun 2010, 396:921-926.
-
(2010)
Biochem Biophys Res Commun
, vol.396
, pp. 921-926
-
-
Tilley, D.G.1
Nguyen, A.D.2
Rockman, H.A.3
-
46
-
-
33845903110
-
Functional selectivity and classical concepts of quantitative pharmacology
-
Urban J.D., Clarke W.P., von Zastrow M., et al. Functional selectivity and classical concepts of quantitative pharmacology. J Pharmacol Exp Ther 2007, 320:1-13.
-
(2007)
J Pharmacol Exp Ther
, vol.320
, pp. 1-13
-
-
Urban, J.D.1
Clarke, W.P.2
von Zastrow, M.3
-
47
-
-
64949190067
-
Blood pressure reduction and renin-angiotensin system inhibition for prevention of congestive heart failure: A meta-analysis
-
Verdecchia P., Angeli F., Cavallini C., et al. Blood pressure reduction and renin-angiotensin system inhibition for prevention of congestive heart failure: A meta-analysis. Eur Heart J 2009, 30:679-688.
-
(2009)
Eur Heart J
, vol.30
, pp. 679-688
-
-
Verdecchia, P.1
Angeli, F.2
Cavallini, C.3
-
48
-
-
78649609643
-
Selectively engaging beta-arrestins at the angiotensin II type 1 receptor reduces blood pressure and increases cardiac performance
-
Violin J.D., DeWire S.M., Yamashita D., et al. Selectively engaging beta-arrestins at the angiotensin II type 1 receptor reduces blood pressure and increases cardiac performance. J Pharmacol Exp Ther 2010, 335:572-579.
-
(2010)
J Pharmacol Exp Ther
, vol.335
, pp. 572-579
-
-
Violin, J.D.1
DeWire, S.M.2
Yamashita, D.3
-
49
-
-
6344258936
-
2+/calmodulin kinase signaling pathway
-
2+/calmodulin kinase signaling pathway. Circ Res 2004, 95:798-806.
-
(2004)
Circ Res
, vol.95
, pp. 798-806
-
-
Wang, W.1
Zhu, W.2
Wang, S.3
-
50
-
-
0141703263
-
Independent β-arrestin 2 and G protein-mediated pathways for angiotensin II activation of extracellular signal-regulated kinases 1 and 2
-
Wei H., Ahn S., Shenoy S.K., et al. Independent β-arrestin 2 and G protein-mediated pathways for angiotensin II activation of extracellular signal-regulated kinases 1 and 2. Proc Natl Acad Sci USA 2003, 100:10782-10787.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 10782-10787
-
-
Wei, H.1
Ahn, S.2
Shenoy, S.K.3
-
52
-
-
79952488185
-
Therapeutic potential of β-arrestin- and G protein-biased agonists
-
Whalen E.J., Rajagopal S., Lefkowitz R.J. Therapeutic potential of β-arrestin- and G protein-biased agonists. Trends Mol Med 2011, 17:126-139.
-
(2011)
Trends Mol Med
, vol.17
, pp. 126-139
-
-
Whalen, E.J.1
Rajagopal, S.2
Lefkowitz, R.J.3
-
53
-
-
36749094552
-
A unique mechanism of beta-blocker action: Carvedilol stimulates beta-arrestin signaling
-
Wisler J.W., DeWire S.M., Whalen E.J., et al. A unique mechanism of beta-blocker action: Carvedilol stimulates beta-arrestin signaling. Proc Natl Acad Sci USA 2007, 104:16657-16662.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 16657-16662
-
-
Wisler, J.W.1
DeWire, S.M.2
Whalen, E.J.3
-
54
-
-
77956998735
-
Global phosphorylation analysis of beta-arrestin-mediated signaling downstream of a seven transmembrane receptor (7TMR)
-
Xiao K., Sun J., Kim J., et al. Global phosphorylation analysis of beta-arrestin-mediated signaling downstream of a seven transmembrane receptor (7TMR). Proc Natl Acad Sci USA 2010, 107:15299-15304.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 15299-15304
-
-
Xiao, K.1
Sun, J.2
Kim, J.3
-
55
-
-
70349613570
-
β1-Adrenergic receptors stimulate cardiac contractility and CaMKII activation in vivo and enhance cardiac dysfunction following myocardial infarction
-
Yoo B., Lemaire A., Mangmool S., et al. β1-Adrenergic receptors stimulate cardiac contractility and CaMKII activation in vivo and enhance cardiac dysfunction following myocardial infarction. Am J Physiol Heart Circ Physiol 2009, 297:H1377-H1386.
-
(2009)
Am J Physiol Heart Circ Physiol
, vol.297
-
-
Yoo, B.1
Lemaire, A.2
Mangmool, S.3
-
56
-
-
27644468385
-
αi coupling causes hypertrophy and bradycardia in transgenic mice
-
αi coupling causes hypertrophy and bradycardia in transgenic mice. J Clin Invest 2005, 115:3045-3056.
-
(2005)
J Clin Invest
, vol.115
, pp. 3045-3056
-
-
Zhai, P.1
Yamamoto, M.2
Galeotti, J.3
-
57
-
-
0038643573
-
The deltaC isoform of CaMKII is activated in cardiac hypertrophy and induces dilated cardiomyopathy and heart failure
-
Zhang T., Maier L.S., Dalton N.D., et al. The deltaC isoform of CaMKII is activated in cardiac hypertrophy and induces dilated cardiomyopathy and heart failure. Circ Res 2003, 92:912-919.
-
(2003)
Circ Res
, vol.92
, pp. 912-919
-
-
Zhang, T.1
Maier, L.S.2
Dalton, N.D.3
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