Riluzole and gabapentinoids activate glutamate transporters to facilitate glutamate-induced glutamate release from cultured astrocytes

European Journal of Pharmacology

Volumn 677, Issue 1-3, 2012, Pages 87-92

  Yoshizumi, Masaru ^a   Eisenach, James C ^a   Hayashida, Ken Ichiro ^a  

^a WAKE FOREST SCHOOL OF MEDICINE   (United States)

Author keywords

Astrocyte; Gabapentin; Glutamate transporter; Riluzole

Indexed keywords

2 [2 [4 (4 NITROBENZYLOXY)PHENYL]ETHYL]ISOTHIOUREA METHANESULFONATE; 3 EXO AMINOBICYCLO [2.2.1] HEPTANE 2 EXO CARBOXYLIC ACID; 3 HYDROXYASPARTIC ACID; ADENOSINE TRIPHOSPHATE; CALCIUM ION; CARBOXYLIC ACID DERIVATIVE; GABAPENTIN; GLUTAMATE TRANSPORTER; GLUTAMIC ACID; ISOLEUCINE; PREGABALIN; RILUZOLE; THREO BETA BENZYLOXYASPARTIC ACID; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; CALCIUM CELL LEVEL; CALCIUM SIGNALING; CALCIUM TRANSPORT; CONTROLLED STUDY; DRUG TARGETING; NERVE CELL CULTURE; NEUROTRANSMITTER RELEASE; NEUROTRANSMITTER UPTAKE; NEWBORN; NONHUMAN; PHARMACOLOGICAL BLOCKING; PRIORITY JOURNAL; RAT; SODIUM CALCIUM EXCHANGE;

AMINES; AMINO ACID TRANSPORT SYSTEM X-AG; ANIMALS; ASTROCYTES; BIOLOGICAL TRANSPORT; CALCIUM; CELLS, CULTURED; CYCLOHEXANECARBOXYLIC ACIDS; GAMMA-AMINOBUTYRIC ACID; GLUTAMIC ACID; INTRACELLULAR SPACE; LIGANDS; PROTEIN SUBUNITS; RATS; RILUZOLE; SODIUM;

EID: 84856284864     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2011.12.015     Document Type: Article

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