Ubiquinone (coenzyme Q10) prevents renal mitochondrial dysfunction in an experimental model of type 2 diabetes

Free Radical Biology and Medicine

Volumn 52, Issue 3, 2012, Pages 716-723

  Sourris, Karly C ^a,b   Harcourt, Brooke E ^a,b   Tang, Peter H ^c   Morley, Amy L ^a   Huynh, Karina ^a,b   Penfold, Sally A ^a   Coughlan, Melinda T ^a,b   Cooper, Mark E ^a,b   Nguyen, Tuong Vi ^a   Ritchie, Rebecca H ^a,b   Forbes, Josephine M ^a,b,d  

^a BAKER IDI HEART AND DIABETES INSTITUTE   (Australia)

^b MONASH UNIVERSITY   (Australia)

^c UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^d MATER MEDICAL RESEARCH INSTITUTE   (Australia)

Author keywords

Coenzyme Q; Diabetic nephropathy; Free radicals; Mitochondrial dysfunction

Indexed keywords

ADENOSINE TRIPHOSPHATE; ALBUMIN; COLLAGEN; CREATININE; HYDROGEN PEROXIDE; SUCCINATE DEHYDROGENASE (UBIQUINONE); SUPEROXIDE; SUPEROXIDE DISMUTASE; UBIDECARENONE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DIABETIC NEPHROPATHY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; ENZYME ACTIVITY; FEMALE; FOLLOW UP; KIDNEY CORTEX; MITOCHONDRIAL MEMBRANE POTENTIAL; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; OXIDATION; PRIORITY JOURNAL; PROTEIN URINE LEVEL;

ADENOSINE TRIPHOSPHATE; ALBUMINURIA; ANIMALS; CITRATE (SI)-SYNTHASE; CREATININE; CYSTATIN C; DIABETES MELLITUS, TYPE 2; DIABETIC NEPHROPATHIES; FEMALE; KIDNEY; KIDNEY FUNCTION TESTS; MEMBRANE POTENTIAL, MITOCHONDRIAL; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; MICE, OBESE; MITOCHONDRIA; OXIDATION-REDUCTION; RANDOM ALLOCATION; REACTIVE OXYGEN SPECIES; UBIQUINONE;

MUS;

EID: 84856239775     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2011.11.017     Document Type: Article

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