Elucidation of the sugar recognition ability of the lectin domain of UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 3 by using unnatural glycopeptide substrates

Glycobiology

Volumn 22, Issue 3, 2012, Pages 429-438

  Yoshimura, Yayoi ^a,b   Nudelman, Aaron S ^c   Levery, Steven B ^c   Wandall, Hans H ^c   Bennett, Eric P ^c   Hindsgaul, Ole ^b   Clausen, Henrik ^c   Nishimura, Shin Ichiro ^a  

^a HOKKAIDO UNIVERSITY   (Japan)

^b CARLSBERG LABORATORY   (Denmark)

^c UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

ETD MS MS; lectin domain; mucin type O glycosylation; polypeptide GalNAc transferase; unnatural glycopeptide substrate

Indexed keywords

ALPHA LEVO FUCOSE O THREONINE; ALPHA N ACETYL DEXTRO GALACTOSAMINE O THREONINE; BETA N ACETYL DEXTRO GALACTOSAMINE O THREONINE; BETA N ACETYL DEXTRO GLUCOSAMINE O THREONINE; GLYCOPEPTIDE; LECTIN; MUCIN 5AC; N ACETYLGALACTOSAMINE; N ACETYLGALACTOSAMINYLTRANSFERASE 3; N ACETYLGLUCOSAMINE; POLYPEPTIDE; SUGAR; UNCLASSIFIED DRUG;

ANALYTIC METHOD; ARTICLE; ASSAY; CONTROLLED STUDY; ELECTRON TRANSFER DISSOCIATION; ENZYME SUBSTRATE; GLYCOSYLATION; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; PRIORITY JOURNAL; PROTEIN DOMAIN; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SYNTHESIS; TANDEM MASS SPECTROMETRY; TANDEM REPEAT;

AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; BINDING, COMPETITIVE; CELL LINE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; ENZYME ASSAYS; FUCOSE; GALACTOSAMINE; GLYCOPEPTIDES; GLYCOSYLATION; HUMANS; MOLECULAR SEQUENCE DATA; MUCIN 5AC; N-ACETYLGALACTOSAMINYLTRANSFERASES; PEPTIDES; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; SUBSTRATE SPECIFICITY;

EID: 84856238781     PISSN: 09596658     EISSN: 14602423     Source Type: Journal    
DOI: 10.1093/glycob/cwr159     Document Type: Article

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