Glycopeptide-preferring polypeptide GalNAc transferase 10 (ppGalNAc T10), involved in mucin-type O-glycosylation, has a unique GalNAc-O-Ser/Thr-binding site in its catalytic domain not found in ppGalNAc T1 or T2

Journal of Biological Chemistry

Volumn 284, Issue 30, 2009, Pages 20387-20397

  Perrine, Cynthia L ^a   Ganguli, Anjali ^b,e   Wu, Peng ^b,f   Bertozzi, Carolyn R ^b   Fritz, Timothy A ^b,g   Raman, Jayalakshmi ^b   Tabak, Lawrence A ^b   Gerken, Thomas A ^a,c,d  

^a CASE WESTERN RESERVE UNIVERSITY   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c LAWRENCE BERKELEY NATIONAL LABORATORY   (United States)

^d NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^e Forest Laboratories   (United States)

^f ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^g CENTER FOR BIOLOGICS EVALUATION AND RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACCEPTOR SITES; CATALYTIC DOMAINS; FILLING IN; GLYCOPEPTIDE; GLYCOSYLATED; HYDROPHILIC RESIDUES; ISOFORM; ISOFORMS; O-GLYCOSYLATION; PEPTIDE SUBSTRATES; SUBSTRATE SPECIFICITY;

AMINES; BINDING ENERGY; BINDING SITES; ENZYMES; ESTERIFICATION; GLYCOSYLATION; INTERNET PROTOCOLS; SUGAR (SUCROSE);

SUBSTRATES;

GLYCOPEPTIDE; ISOPROTEIN; MUCIN; N ALPHA ACETYLGALACTOSAMINYLTRANSFERASE 1; N ALPHA ACETYLGALACTOSAMINYLTRANSFERASE 10; N ALPHA ACETYLGALACTOSAMINYLTRANSFERASE 2; POLYPEPTIDE; SERINE; THREONINE; UNCLASSIFIED DRUG;

ARTICLE; BINDING SITE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; ENZYME SPECIFICITY; ENZYME SUBSTRATE; GLYCOSYLATION; HYDROPHILICITY; HYDROPHOBICITY; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; PROTEIN VARIANT;

AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; BIOTINYLATION; CATALYTIC DOMAIN; CATTLE; GLYCOPEPTIDES; GLYCOSYLATION; HUMANS; MOLECULAR SEQUENCE DATA; MUCINS; N-ACETYLGALACTOSAMINYLTRANSFERASES; SUBSTRATE SPECIFICITY;

EID: 67749133871     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.017236     Document Type: Article

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