An essential epitope of anti-MUC1 monoclonal antibody KL-6 revealed by focused glycopeptide library

Journal of the American Chemical Society

Volumn 131, Issue 47, 2009, Pages 17102-17109

  Ohyabu, Naoki ^a   Hinou, Hiroshi ^a   Matsushita, Takahiko ^a   Izumi, Ryukou ^a   Shimizu, Hiroki ^b   Kawamoto, Keiko ^c   Numata, Yoshito ^c   Togame, Hiroko ^a   Takemoto, Hiroshi ^a   Kondo, Hirosato ^c   Nishimura, Shin Ichiro ^a,b  

^a HOKKAIDO UNIVERSITY   (Japan)

^b NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY AIST   (Japan)

^c SHIONOGI AND CO LTD   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING AFFINITIES; BREAST CANCER; CANCER VACCINE; COLORECTAL ADENOCARCINOMA; COMPOUND LIBRARIES; DIAGNOSTIC PROTOCOLS; GLYCOPEPTIDE LIBRARY; GLYCOPEPTIDES; HEPATOCELLULAR CARCINOMA; HEPTAPEPTIDES; HIGH MOLECULAR WEIGHT; HUMAN SERUM; IMMUNOTHERAPEUTICS; MUC1 GLYCOPEPTIDES; MUC1 GLYCOPROTEIN; NOVEL STRATEGIES;

AMINES; ANTIGENS; BINDING ENERGY; BIOMARKERS; ESTERIFICATION; GLYCOPROTEINS; GLYCOSYLATION; MONOCLONAL ANTIBODIES; SUGAR (SUCROSE); SUGARS; SURFACE PLASMON RESONANCE; TUMORS; VACCINES;

PEPTIDES;

GLYCOPEPTIDE; HEPTAPEPTIDE; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY KL 6; MUCIN 1; N ACETYLGALACTOSAMINE; PEPTIDE LIBRARY; PROLYLASPARTYLTHREONYLARGINYLPROLYLALANYLPROLINE; TUMOR MARKER; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ANTIBODY SPECIFICITY; ANTIGEN RECOGNITION; ARTICLE; BINDING COMPETITION; BIOTINYLATION; CONCENTRATION RESPONSE; ENZYME LINKED IMMUNOSORBENT ASSAY; EPITOPE MAPPING; INTERSTITIAL PNEUMONIA;

ANTIBODIES, MONOCLONAL; ENZYME-LINKED IMMUNOSORBENT ASSAY; GLYCOPEPTIDES; HUMANS; MUCIN-1;

EID: 72249100589     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja903361f     Document Type: Article

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