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Volumn 241, Issue 2, 2012, Pages 257-269

ΔNp63 is regulated by BMP4 signaling and is required for early epidermal development in Xenopus

Author keywords

Np63; Apoptosis; BMP4; Epidermis; Specification

Indexed keywords

BONE MORPHOGENETIC PROTEIN 4; PROTEIN BAX; PROTEIN BCL 2; PROTEIN DELTA NP63; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

EID: 84856226759     PISSN: 10588388     EISSN: 10970177     Source Type: Journal    
DOI: 10.1002/dvdy.23706     Document Type: Article
Times cited : (21)

References (76)
  • 1
    • 0029856611 scopus 로고    scopus 로고
    • Amphibian Bufo arenarum vitronectin-like protein: its localization during oogenesis
    • Aybar MJ, Genta SB, Villecco EI, Riera AN, Sanchez SS. 1996. Amphibian Bufo arenarum vitronectin-like protein: its localization during oogenesis. Int J Dev Biol 40: 997-1008.
    • (1996) Int J Dev Biol , vol.40 , pp. 997-1008
    • Aybar, M.J.1    Genta, S.B.2    Villecco, E.I.3    Riera, A.N.4    Sanchez, S.S.5
  • 2
    • 0037326619 scopus 로고    scopus 로고
    • Snail precedes slug in the genetic cascade required for the specification and migration of the Xenopus neural crest
    • Aybar MJ, Nieto MA, Mayor R. 2003. Snail precedes slug in the genetic cascade required for the specification and migration of the Xenopus neural crest. Development 130: 483-494.
    • (2003) Development , vol.130 , pp. 483-494
    • Aybar, M.J.1    Nieto, M.A.2    Mayor, R.3
  • 3
    • 0036791348 scopus 로고    scopus 로고
    • How death shapes life during development
    • Baehrecke EH. 2002. How death shapes life during development. Nat Rev Mol Cell Biol 3: 779-787.
    • (2002) Nat Rev Mol Cell Biol , vol.3 , pp. 779-787
    • Baehrecke, E.H.1
  • 4
    • 0036001336 scopus 로고    scopus 로고
    • Zebrafish DeltaNp63 is a direct target of Bmp signaling and encodes a transcriptional repressor blocking neural specification in the ventral ectoderm
    • Bakkers J, Hild M, Kramer C, Furutani-Seiki M, Hammerschmidt M. 2002. Zebrafish DeltaNp63 is a direct target of Bmp signaling and encodes a transcriptional repressor blocking neural specification in the ventral ectoderm. Dev Cell 2: 617-627.
    • (2002) Dev Cell , vol.2 , pp. 617-627
    • Bakkers, J.1    Hild, M.2    Kramer, C.3    Furutani-Seiki, M.4    Hammerschmidt, M.5
  • 5
    • 16844386318 scopus 로고    scopus 로고
    • IGFBP-3 is a direct target of transcriptional regulation by DeltaNp63alpha in squamous epithelium
    • Barbieri CE, Perez CA, Johnson KN, Ely KA, Billheimer D, Pietenpol JA. 2005. IGFBP-3 is a direct target of transcriptional regulation by DeltaNp63alpha in squamous epithelium. Cancer Res 65: 2314-2320.
    • (2005) Cancer Res , vol.65 , pp. 2314-2320
    • Barbieri, C.E.1    Perez, C.A.2    Johnson, K.N.3    Ely, K.A.4    Billheimer, D.5    Pietenpol, J.A.6
  • 6
    • 33747872417 scopus 로고    scopus 로고
    • Loss of p63 leads to increased cell migration and up-regulation of genes involved in invasion and metastasis
    • Barbieri CE, Tang LJ, Brown KA, Pietenpol JA. 2006. Loss of p63 leads to increased cell migration and up-regulation of genes involved in invasion and metastasis. Cancer Res 66: 7589-7597.
    • (2006) Cancer Res , vol.66 , pp. 7589-7597
    • Barbieri, C.E.1    Tang, L.J.2    Brown, K.A.3    Pietenpol, J.A.4
  • 8
    • 0034235282 scopus 로고    scopus 로고
    • Is chordin a long-range- or short-range-acting factor? Roles for BMP1-related metalloproteases in chordin and BMP4 autofeedback loop regulation
    • Blitz IL, Shimmi O, Wunnenberg-Stapleton K, O'Connor MB, Cho KW. 2000. Is chordin a long-range- or short-range-acting factor? Roles for BMP1-related metalloproteases in chordin and BMP4 autofeedback loop regulation. Dev Biol 223: 120-138.
    • (2000) Dev Biol , vol.223 , pp. 120-138
    • Blitz, I.L.1    Shimmi, O.2    Wunnenberg-Stapleton, K.3    O'Connor, M.B.4    Cho, K.W.5
  • 9
    • 53649102358 scopus 로고    scopus 로고
    • A new role for the Endothelin-1/Endothelin-A receptor signaling during early neural crest specification
    • Bonano M, Tribulo C, De Calisto J, Marchant L, Sanchez SS, Mayor R, Aybar MJ. 2008. A new role for the Endothelin-1/Endothelin-A receptor signaling during early neural crest specification. Dev Biol 323: 114-129.
    • (2008) Dev Biol , vol.323 , pp. 114-129
    • Bonano, M.1    Tribulo, C.2    De Calisto, J.3    Marchant, L.4    Sanchez, S.S.5    Mayor, R.6    Aybar, M.J.7
  • 11
    • 74549130412 scopus 로고    scopus 로고
    • Conservation of DNA-binding specificity and oligomerisation properties within the p53 family
    • Brandt T, Petrovich M, Joerger AC, Veprintsev DB. 2009. Conservation of DNA-binding specificity and oligomerisation properties within the p53 family. BMC Genomics 10: 628.
    • (2009) BMC Genomics , vol.10 , pp. 628
    • Brandt, T.1    Petrovich, M.2    Joerger, A.C.3    Veprintsev, D.B.4
  • 12
    • 12344249105 scopus 로고    scopus 로고
    • Six1 promotes a placodal fate within the lateral neurogenic ectoderm by functioning as both a transcriptional activator and repressor
    • Brugmann SA, Pandur PD, Kenyon KL, Pignoni F, Moody SA. 2004. Six1 promotes a placodal fate within the lateral neurogenic ectoderm by functioning as both a transcriptional activator and repressor. Development 131: 5871-5881.
    • (2004) Development , vol.131 , pp. 5871-5881
    • Brugmann, S.A.1    Pandur, P.D.2    Kenyon, K.L.3    Pignoni, F.4    Moody, S.A.5
  • 15
    • 33748767359 scopus 로고    scopus 로고
    • Grainyhead-like 3, a transcription factor identified in a microarray screen, promotes the specification of the superficial layer of the embryonic epidermis
    • Chalmers AD, Lachani K, Shin Y, Sherwood V, Cho KW, Papalopulu N. 2006. Grainyhead-like 3, a transcription factor identified in a microarray screen, promotes the specification of the superficial layer of the embryonic epidermis. Mech Dev 123: 702-718.
    • (2006) Mech Dev , vol.123 , pp. 702-718
    • Chalmers, A.D.1    Lachani, K.2    Shin, Y.3    Sherwood, V.4    Cho, K.W.5    Papalopulu, N.6
  • 17
    • 71049136612 scopus 로고    scopus 로고
    • p63 Suppresses non-epidermal lineage markers in a bone morphogenetic protein-dependent manner via repression of Smad7
    • De Rosa L, Antonini D, Ferone G, Russo MT, Yu PB, Han R, Missero C. 2009. p63 Suppresses non-epidermal lineage markers in a bone morphogenetic protein-dependent manner via repression of Smad7. J Biol Chem 284: 30574-30582.
    • (2009) J Biol Chem , vol.284 , pp. 30574-30582
    • De Rosa, L.1    Antonini, D.2    Ferone, G.3    Russo, M.T.4    Yu, P.B.5    Han, R.6    Missero, C.7
  • 18
    • 0034743628 scopus 로고    scopus 로고
    • p63alpha and DeltaNp63alpha can induce cell cycle arrest and apoptosis and differentially regulate p53 target genes
    • Dohn M, Zhang S, Chen X. 2001. p63alpha and DeltaNp63alpha can induce cell cycle arrest and apoptosis and differentially regulate p53 target genes. Oncogene 20: 3193-3205.
    • (2001) Oncogene , vol.20 , pp. 3193-3205
    • Dohn, M.1    Zhang, S.2    Chen, X.3
  • 19
    • 79952321348 scopus 로고    scopus 로고
    • Embryonic frog epidermis: a model for the study of cell-cell interactions in the development of mucociliary disease
    • Dubaissi E, Papalopulu N. 2011. Embryonic frog epidermis: a model for the study of cell-cell interactions in the development of mucociliary disease. Dis Model Mech 4: 179-192.
    • (2011) Dis Model Mech , vol.4 , pp. 179-192
    • Dubaissi, E.1    Papalopulu, N.2
  • 20
    • 0036892018 scopus 로고    scopus 로고
    • Complex transcriptional effects of p63 isoforms: identification of novel activation and repression domains
    • Ghioni P, Bolognese F, Duijf PH, Van Bokhoven H, Mantovani R, Guerrini L. 2002. Complex transcriptional effects of p63 isoforms: identification of novel activation and repression domains. Mol Cell Biol 22: 8659-8668.
    • (2002) Mol Cell Biol , vol.22 , pp. 8659-8668
    • Ghioni, P.1    Bolognese, F.2    Duijf, P.H.3    Van Bokhoven, H.4    Mantovani, R.5    Guerrini, L.6
  • 23
    • 0032212681 scopus 로고    scopus 로고
    • Programmed cell death during Xenopus development: a spatio-temporal analysis
    • Hensey C, Gautier J. 1998. Programmed cell death during Xenopus development: a spatio-temporal analysis. Dev Biol 203: 36-48.
    • (1998) Dev Biol , vol.203 , pp. 36-48
    • Hensey, C.1    Gautier, J.2
  • 24
    • 0004498233 scopus 로고
    • Epidermal keratin gene expressed in embryos of Xenopus laevis
    • Jonas E, Sargent TD, Dawid IB. 1985. Epidermal keratin gene expressed in embryos of Xenopus laevis. Proc Natl Acad Sci U S A 82: 5413-5417.
    • (1985) Proc Natl Acad Sci U S A , vol.82 , pp. 5413-5417
    • Jonas, E.1    Sargent, T.D.2    Dawid, I.B.3
  • 27
    • 0942301281 scopus 로고    scopus 로고
    • p63 is the molecular switch for initiation of an epithelial stratification program
    • Koster MI, Kim S, Mills AA, DeMayo FJ, Roop DR. 2004. p63 is the molecular switch for initiation of an epithelial stratification program. Genes & development 18: 126-131.
    • (2004) Genes & development , vol.18 , pp. 126-131
    • Koster, M.I.1    Kim, S.2    Mills, A.A.3    DeMayo, F.J.4    Roop, D.R.5
  • 28
    • 12344252567 scopus 로고    scopus 로고
    • Genetic pathways required for epidermal morphogenesis
    • Koster MI, Roop DR. 2004. Genetic pathways required for epidermal morphogenesis. Eur J Cell Biol 83: 625-629.
    • (2004) Eur J Cell Biol , vol.83 , pp. 625-629
    • Koster, M.I.1    Roop, D.R.2
  • 29
    • 0031901224 scopus 로고    scopus 로고
    • Neural crest induction in Xenopus: evidence for a two-signal model
    • LaBonne C, Bronner-Fraser M. 1998. Neural crest induction in Xenopus: evidence for a two-signal model. Development 125: 2403-2414.
    • (1998) Development , vol.125 , pp. 2403-2414
    • LaBonne, C.1    Bronner-Fraser, M.2
  • 30
    • 33646711244 scopus 로고    scopus 로고
    • p63 regulates multiple signalling pathways required for ectodermal organogenesis and differentiation
    • Laurikkala J, Mikkola ML, James M, Tummers M, Mills AA, Thesleff I. 2006. p63 regulates multiple signalling pathways required for ectodermal organogenesis and differentiation. Development 133: 1553-1563.
    • (2006) Development , vol.133 , pp. 1553-1563
    • Laurikkala, J.1    Mikkola, M.L.2    James, M.3    Tummers, M.4    Mills, A.A.5    Thesleff, I.6
  • 31
    • 0036114018 scopus 로고    scopus 로고
    • A dominant-negative form of p63 is required for epidermal proliferation in zebrafish
    • Lee H, Kimelman D. 2002. A dominant-negative form of p63 is required for epidermal proliferation in zebrafish. Dev Cell 2: 607-616.
    • (2002) Dev Cell , vol.2 , pp. 607-616
    • Lee, H.1    Kimelman, D.2
  • 32
  • 36
    • 0035059668 scopus 로고    scopus 로고
    • Xenopus p63 expression in early ectoderm and neurectoderm
    • Lu P, Barad M, Vize PD. 2001. Xenopus p63 expression in early ectoderm and neurectoderm. Mech Dev 102: 275-278.
    • (2001) Mech Dev , vol.102 , pp. 275-278
    • Lu, P.1    Barad, M.2    Vize, P.D.3
  • 37
    • 0034913235 scopus 로고    scopus 로고
    • Differential regulation of Dlx gene expression by a BMP morphogenetic gradient
    • Luo T, Matsuo-Takasaki M, Lim JH, Sargent TD. 2001. Differential regulation of Dlx gene expression by a BMP morphogenetic gradient. Int J Dev Biol 45: 681-684.
    • (2001) Int J Dev Biol , vol.45 , pp. 681-684
    • Luo, T.1    Matsuo-Takasaki, M.2    Lim, J.H.3    Sargent, T.D.4
  • 38
    • 0036570364 scopus 로고    scopus 로고
    • Transcription factor AP-2 is an essential and direct regulator of epidermal development in Xenopus
    • Luo T, Matsuo-Takasaki M, Thomas ML, Weeks DL, Sargent TD. 2002. Transcription factor AP-2 is an essential and direct regulator of epidermal development in Xenopus. Dev Biol 245: 136-144.
    • (2002) Dev Biol , vol.245 , pp. 136-144
    • Luo, T.1    Matsuo-Takasaki, M.2    Thomas, M.L.3    Weeks, D.L.4    Sargent, T.D.5
  • 40
    • 73349128422 scopus 로고    scopus 로고
    • Nkx-2.3 gene in mouse epidermal maturation
    • Ma CM. 2009. Nkx-2.3 gene in mouse epidermal maturation. Biol Res 42: 267-280.
    • (2009) Biol Res , vol.42 , pp. 267-280
    • Ma, C.M.1
  • 41
    • 0032525780 scopus 로고    scopus 로고
    • The inductive properties of mesoderm suggest that the neural crest cells are specified by a BMP gradient
    • Marchant L, Linker C, Ruiz P, Guerrero N, Mayor R. 1998. The inductive properties of mesoderm suggest that the neural crest cells are specified by a BMP gradient. Dev Biol 198: 319-329.
    • (1998) Dev Biol , vol.198 , pp. 319-329
    • Marchant, L.1    Linker, C.2    Ruiz, P.3    Guerrero, N.4    Mayor, R.5
  • 43
    • 33847055513 scopus 로고    scopus 로고
    • p63 in skin appendage development
    • Mikkola ML. 2007. p63 in skin appendage development. Cell Cycle 6: 285-290.
    • (2007) Cell Cycle , vol.6 , pp. 285-290
    • Mikkola, M.L.1
  • 44
    • 0033594491 scopus 로고    scopus 로고
    • p63 is a p53 homologue required for limb and epidermal morphogenesis
    • Mills AA, Zheng B, Wang XJ, Vogel H, Roop DR, Bradley A. 1999. p63 is a p53 homologue required for limb and epidermal morphogenesis. Nature 398: 708-713.
    • (1999) Nature , vol.398 , pp. 708-713
    • Mills, A.A.1    Zheng, B.2    Wang, X.J.3    Vogel, H.4    Roop, D.R.5    Bradley, A.6
  • 45
    • 77952743819 scopus 로고    scopus 로고
    • Dominant negative (DeltaN) p63alpha induces drug resistance in hepatocellular carcinoma by interference with apoptosis signaling pathways
    • Mundt HM, Stremmel W, Melino G, Krammer PH, Schilling T, Muller M. 2010. Dominant negative (DeltaN) p63alpha induces drug resistance in hepatocellular carcinoma by interference with apoptosis signaling pathways. Biochem Biophys Res Commun 396: 335-341.
    • (2010) Biochem Biophys Res Commun , vol.396 , pp. 335-341
    • Mundt, H.M.1    Stremmel, W.2    Melino, G.3    Krammer, P.H.4    Schilling, T.5    Muller, M.6
  • 48
    • 0029843358 scopus 로고    scopus 로고
    • The Xvent-2 homeobox gene is part of the BMP-4 signalling pathway controlling [correction of controling] dorsoventral patterning of Xenopus mesoderm
    • Onichtchouk D, Gawantka V, Dosch R, Delius H, Hirschfeld K, Blumenstock C, Niehrs C. 1996. The Xvent-2 homeobox gene is part of the BMP-4 signalling pathway controlling [correction of controling] dorsoventral patterning of Xenopus mesoderm. Development 122: 3045-3053.
    • (1996) Development , vol.122 , pp. 3045-3053
    • Onichtchouk, D.1    Gawantka, V.2    Dosch, R.3    Delius, H.4    Hirschfeld, K.5    Blumenstock, C.6    Niehrs, C.7
  • 49
    • 0034266073 scopus 로고    scopus 로고
    • Xenopus Six1 gene is expressed in neurogenic cranial placodes and maintained in the differentiating lateral lines
    • Pandur PD, Moody SA. 2000. Xenopus Six1 gene is expressed in neurogenic cranial placodes and maintained in the differentiating lateral lines. Mech Dev 96: 253-257.
    • (2000) Mech Dev , vol.96 , pp. 253-257
    • Pandur, P.D.1    Moody, S.A.2
  • 51
  • 52
    • 79951528196 scopus 로고    scopus 로고
    • Specification of ion transport cells in the Xenopus larval skin
    • Quigley IK, Stubbs JL, Kintner C. 2011. Specification of ion transport cells in the Xenopus larval skin. Development 138: 705-714.
    • (2011) Development , vol.138 , pp. 705-714
    • Quigley, I.K.1    Stubbs, J.L.2    Kintner, C.3
  • 54
    • 34247252481 scopus 로고    scopus 로고
    • A functional enhancer of keratin14 is a direct transcriptional target of deltaNp63
    • Romano RA, Birkaya B, Sinha S. 2007. A functional enhancer of keratin14 is a direct transcriptional target of deltaNp63. J Invest Dermatol 127: 1175-1186.
    • (2007) J Invest Dermatol , vol.127 , pp. 1175-1186
    • Romano, R.A.1    Birkaya, B.2    Sinha, S.3
  • 55
    • 66049096917 scopus 로고    scopus 로고
    • An active role of the DeltaN isoform of p63 in regulating basal keratin genes K5 and K14 and directing epidermal cell fate
    • Romano RA, Ortt K, Birkaya B, Smalley K, Sinha S. 2009. An active role of the DeltaN isoform of p63 in regulating basal keratin genes K5 and K14 and directing epidermal cell fate. PloS One 4: e5623.
    • (2009) PloS One , vol.4
    • Romano, R.A.1    Ortt, K.2    Birkaya, B.3    Smalley, K.4    Sinha, S.5
  • 56
    • 0029557213 scopus 로고
    • Programmed cell death in development
    • Sanders EJ, Wride MA. 1995. Programmed cell death in development. Int Rev Cytol 163: 105-173.
    • (1995) Int Rev Cytol , vol.163 , pp. 105-173
    • Sanders, E.J.1    Wride, M.A.2
  • 57
    • 0034927392 scopus 로고    scopus 로고
    • Requirement of FoxD3-class signaling for neural crest determination in Xenopus
    • Sasai N, Mizuseki K, Sasai Y. 2001. Requirement of FoxD3-class signaling for neural crest determination in Xenopus. Development 128: 2525-2536.
    • (2001) Development , vol.128 , pp. 2525-2536
    • Sasai, N.1    Mizuseki, K.2    Sasai, Y.3
  • 58
    • 0031080963 scopus 로고    scopus 로고
    • Ectodermal patterning in vertebrate embryos
    • Sasai Y, De Robertis EM. 1997. Ectodermal patterning in vertebrate embryos. Dev Biol 182: 5-20.
    • (1997) Dev Biol , vol.182 , pp. 5-20
    • Sasai, Y.1    De Robertis, E.M.2
  • 59
    • 0029009530 scopus 로고
    • Regulation of neural induction by the Chd and Bmp-4 antagonistic patterning signals in Xenopus
    • Sasai Y, Lu B, Steinbeisser H, De Robertis EM. 1995. Regulation of neural induction by the Chd and Bmp-4 antagonistic patterning signals in Xenopus. Nature 376: 333-336.
    • (1995) Nature , vol.376 , pp. 333-336
    • Sasai, Y.1    Lu, B.2    Steinbeisser, H.3    De Robertis, E.M.4
  • 60
    • 3042587085 scopus 로고    scopus 로고
    • Molecular anatomy of placode development in Xenopus laevis
    • Schlosser G, Ahrens K. 2004. Molecular anatomy of placode development in Xenopus laevis. Dev Biol 271: 439-466.
    • (2004) Dev Biol , vol.271 , pp. 439-466
    • Schlosser, G.1    Ahrens, K.2
  • 61
    • 34247511981 scopus 로고    scopus 로고
    • p63 Is essential for the proliferative potential of stem cells in stratified epithelia
    • Senoo M, Pinto F, Crum CP, McKeon F. 2007. p63 Is essential for the proliferative potential of stem cells in stratified epithelia. Cell 129: 523-536.
    • (2007) Cell , vol.129 , pp. 523-536
    • Senoo, M.1    Pinto, F.2    Crum, C.P.3    McKeon, F.4
  • 62
    • 0031239298 scopus 로고    scopus 로고
    • Regulation of epidermal induction by BMP2 and BMP7 signaling
    • Suzuki A, Kaneko E, Ueno N, Hemmati-Brivanlou A. 1997a. Regulation of epidermal induction by BMP2 and BMP7 signaling. Dev Biol 189: 112-122.
    • (1997) Dev Biol , vol.189 , pp. 112-122
    • Suzuki, A.1    Kaneko, E.2    Ueno, N.3    Hemmati-Brivanlou, A.4
  • 63
    • 0030964620 scopus 로고    scopus 로고
    • Xenopus msx1 mediates epidermal induction and neural inhibition by BMP4
    • Suzuki A, Ueno N, Hemmati-Brivanlou A. 1997b. Xenopus msx1 mediates epidermal induction and neural inhibition by BMP4. Development 124: 3037-3044.
    • (1997) Development , vol.124 , pp. 3037-3044
    • Suzuki, A.1    Ueno, N.2    Hemmati-Brivanlou, A.3
  • 66
    • 0346505182 scopus 로고    scopus 로고
    • Regulation of Msx genes by a Bmp gradient is essential for neural crest specification
    • Tribulo C, Aybar MJ, Nguyen VH, Mullins MC, Mayor R. 2003. Regulation of Msx genes by a Bmp gradient is essential for neural crest specification. Development 130: 6441-6452.
    • (2003) Development , vol.130 , pp. 6441-6452
    • Tribulo, C.1    Aybar, M.J.2    Nguyen, V.H.3    Mullins, M.C.4    Mayor, R.5
  • 67
    • 14244260205 scopus 로고    scopus 로고
    • A balance between the anti-apoptotic activity of Slug and the apoptotic activity of msx1 is required for the proper development of the neural crest
    • Tribulo C, Aybar MJ, Sanchez SS, Mayor R. 2004. A balance between the anti-apoptotic activity of Slug and the apoptotic activity of msx1 is required for the proper development of the neural crest. Dev Biol 275: 325-342.
    • (2004) Dev Biol , vol.275 , pp. 325-342
    • Tribulo, C.1    Aybar, M.J.2    Sanchez, S.S.3    Mayor, R.4
  • 68
    • 33751230475 scopus 로고    scopus 로고
    • p63 regulates proliferation and differentiation of developmentally mature keratinocytes
    • Truong AB, Kretz M, Ridky TW, Kimmel R, Khavari PA. 2006. p63 regulates proliferation and differentiation of developmentally mature keratinocytes. Genes Dev 20: 3185-3197.
    • (2006) Genes Dev , vol.20 , pp. 3185-3197
    • Truong, A.B.1    Kretz, M.2    Ridky, T.W.3    Kimmel, R.4    Khavari, P.A.5
  • 69
    • 0037377761 scopus 로고    scopus 로고
    • The Delta Np63 alpha phosphoprotein binds the p21 and 14-3-3 sigma promoters in vivo and has transcriptional repressor activity that is reduced by Hay-Wells syndrome-derived mutations
    • Westfall MD, Mays DJ, Sniezek JC, Pietenpol JA. 2003. The Delta Np63 alpha phosphoprotein binds the p21 and 14-3-3 sigma promoters in vivo and has transcriptional repressor activity that is reduced by Hay-Wells syndrome-derived mutations. Mol Cell Biol 23: 2264-2276.
    • (2003) Mol Cell Biol , vol.23 , pp. 2264-2276
    • Westfall, M.D.1    Mays, D.J.2    Sniezek, J.C.3    Pietenpol, J.A.4
  • 70
    • 0029059425 scopus 로고
    • Induction of epidermis and inhibition of neural fate by Bmp-4
    • Wilson PA, Hemmati-Brivanlou A. 1995. Induction of epidermis and inhibition of neural fate by Bmp-4. Nature 376: 331-333.
    • (1995) Nature , vol.376 , pp. 331-333
    • Wilson, P.A.1    Hemmati-Brivanlou, A.2
  • 71
    • 0030886059 scopus 로고    scopus 로고
    • Concentration-dependent patterning of the Xenopus ectoderm by BMP4 and its signal transducer Smad1
    • Wilson PA, Lagna G, Suzuki A, Hemmati-Brivanlou A. 1997. Concentration-dependent patterning of the Xenopus ectoderm by BMP4 and its signal transducer Smad1. Development 124: 3177-3184.
    • (1997) Development , vol.124 , pp. 3177-3184
    • Wilson, P.A.1    Lagna, G.2    Suzuki, A.3    Hemmati-Brivanlou, A.4
  • 73
    • 0036468523 scopus 로고    scopus 로고
    • On the shoulders of giants: p63, p73 and the rise of p53
    • Yang A, Kaghad M, Caput D, McKeon F. 2002. On the shoulders of giants: p63, p73 and the rise of p53. Trends Genet 18: 90-95.
    • (2002) Trends Genet , vol.18 , pp. 90-95
    • Yang, A.1    Kaghad, M.2    Caput, D.3    McKeon, F.4
  • 74
    • 0032161624 scopus 로고    scopus 로고
    • p63, a p53 homolog at 3q27-29, encodes multiple products with transactivating, death-inducing, and dominant-negative activities
    • Yang A, Kaghad M, Wang Y, Gillett E, Fleming MD, Dotsch V, Andrews NC, Caput D, McKeon F. 1998. p63, a p53 homolog at 3q27-29, encodes multiple products with transactivating, death-inducing, and dominant-negative activities. Mol Cell 2: 305-316.
    • (1998) Mol Cell , vol.2 , pp. 305-316
    • Yang, A.1    Kaghad, M.2    Wang, Y.3    Gillett, E.4    Fleming, M.D.5    Dotsch, V.6    Andrews, N.C.7    Caput, D.8    McKeon, F.9
  • 76
    • 0030598829 scopus 로고    scopus 로고
    • The Spemann organizer signal noggin binds and inactivates bone morphogenetic protein 4
    • Zimmerman LB, De Jesus-Escobar JM, Harland RM. 1996. The Spemann organizer signal noggin binds and inactivates bone morphogenetic protein 4. Cell 86: 599-606.
    • (1996) Cell , vol.86 , pp. 599-606
    • Zimmerman, L.B.1    De Jesus-Escobar, J.M.2    Harland, R.M.3


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