A better prognosis for genetic association studies in mice

Trends in Genetics

Volumn 28, Issue 2, 2012, Pages 62-69

  Zheng, Ming ^a   Dill, David ^b   Peltz, Gary ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Stanford University   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ABCB1B PROTEIN; ADRB2 PROTEIN; AOX1 PROTEIN; ATP1B3 PROTEIN; BIOLOGICAL MARKER; CYP2C29 PROTEIN; GLUCURONOSYLTRANSFERASE 1A1; KCNJ9 PROTEIN; MAPK8 PROTEIN; MESSENGER RNA; NALP1B PROTEIN; PLG PROTEIN; SEROTONIN 3A RECEPTOR; UNCLASSIFIED DRUG;

CANDIDIASIS; DIAGNOSTIC ACCURACY; DIAGNOSTIC VALUE; DISEASE PREDISPOSITION; DNA POLYMORPHISM; FALSE POSITIVE RESULT; GENE; GENE EXPRESSION; GENE LOCUS; GENE MAPPING; GENETIC ASSOCIATION; GENETIC PREDISPOSITION; GENETIC VARIABILITY; GENOTYPE; H2-EALPHA GENE; HEREDITY; HUMAN; INTERMETHOD COMPARISON; NONHUMAN; POSTOPERATIVE PAIN; PRIORITY JOURNAL; QUANTITATIVE TRAIT LOCUS MAPPING; REVIEW; SINGLE NUCLEOTIDE POLYMORPHISM; WITHDRAWAL SYNDROME;

ANIMALS; BIOMEDICAL RESEARCH; GENETIC PREDISPOSITION TO DISEASE; GENOME-WIDE ASSOCIATION STUDY; HAPLOTYPES; HUMANS; MICE; MODELS, GENETIC; PROGNOSIS;

MURINAE; MUS;

EID: 84856218101     PISSN: 01689525     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tig.2011.10.006     Document Type: Review

References (37)

1. Flint J., et al. Strategies for mapping and cloning quantitative trait genes in rodents. Nat. Rev. Genet. 2005, 6:271-286.
2. Payseur B.A., Place M. Prospects for association mapping in classical inbred mouse strains. Genetics 2007, 175:1999-2008.
3. Su W.L., et al. Assessing the prospects of genome-wide association studies performed in inbred mice. Mamm. Genome 2010, 21:143-152.
4. Chu L.F., et al. From mouse to man: the 5-HT3 receptor modulates physical dependence on opioid narcotics. Pharmacogenet. Genomics 2009, 19:193-205.
5. Hu Y., et al. The role of IL-1 in wound biology part I: murine in silico and in vitro experimental analysis. Anesth. Analg. 2010, 111:1525-1533.
6. Hu Y., et al. The role of IL-1 in wound biology part II: in vivo and human translational studies. Anesth. Analg. 2010, 111:1534-1542.
7. Liao G., et al. In silico genetics: identification of a functional element regulating H2-Ea gene expression. Science 2004, 306:690-695.
8. Wang J., et al. Computational genetics: from mouse to man?. Trends Genet. 2005, 21:526-532.
9. Yalcin B., et al. Unexpected complexity in the haplotypes of commonly used inbred strains of laboratory mice. Proc. Natl. Acad. Sci. U.S.A. 2004, 101:9734-9739.
10. Wang J., et al. Haplotypic structure of the mouse genome. Computational Genetics and Genomics: New Tools for Understanding Disease 2005, 71-83. Humana Press. G. Peltz (Ed.).
11. Wade C.M., et al. The mosaic structure of variation in the laboratory mouse genome. Nature 2002, 420:574-578.
12. Kang H.M., et al. Efficient control of population structure in model organism association mapping. Genetics 2008, 178:1709-1723.
13. Kirby A., et al. Fine mapping in 94 inbred mouse strains using a high-density haplotype resource. Genetics 2010, 185:1081-1095.
14. Peltz G., et al. Next-generation computational genetic analysis: multiple complement alleles control survival after Candida albicans infection. Infect. Immun. 2011, 79:4472-4479.
15. Yalcin B., et al. Commercially available outbred mice for genome-wide association studies. PLoS Genet. 2010, 6:e1001085.
16. Zheng M., et al. Computational genetic mapping in mice: 'the ship has sailed'. Sci. Translational Med. 2009, 1. 3ps4.
17. Liu H.-H., et al. An integrative genomic analysis identifies Bhmt2 as a diet-dependent genetic factor protecting against acetaminophen-induced liver toxicity. Genome Res. 2010, 20:28-35.
18. Zhang X., et al. In silico and in vitro pharmacogenetics: aldehyde oxidase rapidly metabolizes a p38 kinase inhibitor. Pharmacogenomics J. 2011, 11:15-24.
19. Smith S.B., et al. Quantitative trait locus and computational mapping identifies Kcnj9 (GIRK3) as a candidate gene affecting analgesia from multiple drug classes. Pharmacogenet. Genomics 2008, 18:231-241.
20. LaCroix-Fralish M.L., et al. The β3 subunit of the Na+, K+-ATPase affects pain sensitivity. Pain 2009, 144:294-302.
21. Guenet J.L., Bonhomme F. Wild mice: an ever-increasing contribution to a popular mammalian model. Trends Genet. 2003, 19:24-31.
22. Reuveni E., et al. The consequence of natural selection on genetic variation in the mouse. Genomics 2010, 95:196-202.
23. Beck J.A., et al. Genealogies of mouse inbred strains. Nat. Genet. 2000, 24:23-25.
24. Valdar W., et al. Genome-wide genetic association of complex traits in heterogeneous stock mice. Nat. Genet. 2006, 38:879-887.
25. Valdar W., et al. Simulating the collaborative cross: power of quantitative trait loci detection and mapping resolution in large sets of recombinant inbred strains of mice. Genetics 2006, 172:1783-1797.
26. Keane T.M., et al. Mouse genomic variation and its effect on phenotypes and gene regulation. Nature 2011, 477:289-294.
27. Chanock S.J., et al. Replicating genotype-phenotype associations. Nature 2007, 447:655-660.
28. Flint J., Mott R. Applying mouse complex-trait resources to behavioural genetics. Nature 2008, 456:724-727.
29. Hutchins L.N., et al. CGDSNPdb: a database resource for error-checked and imputed mouse SNPs. Database 2010, 2010:baq008.
30. Iraqi F.A., et al. The Collaborative Cross, developing a resource for mammalian systems genetics: a status report of the Wellcome Trust cohort. Mamm. Genome 2008, 19:379-381.
31. Guo Y.Y., et al. In silico pharmacogenetics: warfarin metabolism. Nat. Biotechnol. 2006, 24:531-536.
32. Guo Y.Y., et al. In vitro and in silico pharmacogenetic analysis in mice. Proc. Natl. Acad. Sci. U.S.A. 2007, 104:17735-17740.
33. Zaas A.K., et al. Plasminogen alleles influence susceptibility to invasive aspergillosis. PLoS Genet. 2008, 4:e1000101.
34. Tregoning J.S., et al. Genetic susceptibility to the delayed sequelae of RSV infection is MHC-dependent, but modified by other genetic loci. J. Immunol. 2010, 185:5384-5391.
35. Liang D., et al. A genetic analysis of opioid-induced hyperalgesia in mice. Anesthesiology 2006, 104:1054-1062.
36. Liang D.Y., et al. Genetic variants of the P-glycoprotein gene Abcb1b modulate opioid-induced hyperalgesia, tolerance and dependence. Pharmacogenet. Genomics 2006, 16:825-835.
37. Li X., et al. Expression genetics identifies spinal mechanisms supporting formalin late phase behaviors. Mol. Pain 2010, 6:11.