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Bioorganic and Medicinal Chemistry Letters

Volumn 22, Issue 3, 2012, Pages 1402-1407

Identification of novel SAR properties of the Jak2 small molecule inhibitor G6: Significance of the para-hydroxyl orientation

(7) Baskin, Rebekah a Gali, Meghanath a Park, Sung O a Zhao, Zhizhuang Joe b Keser, György M c Bisht, Kirpal S a Sayeski, Peter P a

a UNIVERSITY OF FLORIDA (United States)

b UNIVERSITY OF OKLAHOMA COLLEGE OF MEDICINE (United States)

c BUDAPEST UNIVERSITY OF TECHNOLOGY AND ECONOMICS (Hungary)

Author keywords

G6; Jak2 tyrosine kinase; SAR; Small molecule inhibitor; Stilbenoid

Indexed keywords

ANTINEOPLASTIC AGENT; JANUS KINASE 2; JANUS KINASE 2 INHIBITOR; JANUS TYROSINE KINASE 2 G6 INHIBITOR; STILBENE DERIVATIVE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG STRUCTURE; ENZYME INHIBITION; HUMAN; HUMAN CELL; IN VITRO STUDY; STRUCTURE ACTIVITY RELATION;

ANIMALS; BENZYLAMINES; CELL LINE, TUMOR; CELL SURVIVAL; HYDROXYLATION; JANUS KINASE 2; MICE; MICE, TRANSGENIC; MODELS, MOLECULAR; MOLECULAR STRUCTURE; SMALL MOLECULE LIBRARIES; STILBENES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84856214469 PISSN: 0960894X EISSN: 14643405 Source Type: Journal
DOI: 10.1016/j.bmcl.2011.12.042 Document Type: Article

Times cited : (7)

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