Melphalan-induced apoptosis in multiple myeloma cells is associated with a cleavage of Mcl-1 and Bim and a decrease in the Mcl-1/Bim complex

Oncogene

Volumn 24, Issue 54, 2005, Pages 8076-8079

  Gomez Bougie, Patricia ^a   Oliver, Lisa ^a   Le Gouill, Steven ^a   Bataille, Régis ^a   Amiot, Martine ^a  

^a INSTITUT DE BIOLOGIE   (France)

Author keywords

Bcl 2; BH3 only Bim; Mcl 1; Melphalan; Multiple myeloma

Indexed keywords

BIM PROTEIN; CASPASE; CYTOCHROME C; MELPHALAN; PROTEIN BAX; PROTEIN BCL XL; PROTEIN MCL 1;

APOPTOSIS; ARTICLE; DEATH; DOWN REGULATION; HUMAN; HUMAN CELL; MULTIPLE MYELOMA; MYELOMA CELL; PRIORITY JOURNAL; PROTEIN FUNCTION;

ANTINEOPLASTIC AGENTS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; DOWN-REGULATION; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MELPHALAN; MEMBRANE PROTEINS; MULTIPLE MYELOMA; NEOPLASM PROTEINS; PROTEIN ISOFORMS; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2; TUMOR CELLS, CULTURED;

EID: 28544442011     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/sj.onc.1208949     Document Type: Article

References (27)

1. Bouillet P, Metcalf D, Huang DC, Tarlinton DM, Kay TW, Kontgen F, Adams JM and Strasser A. (1999). Science, 286, 1735-1738.
2. Chen D and Zhou Q. (2004). Proc. Natl. Acad. Sci. USA, 101, 1235-1240.
3. Clem RJ, Cheng EH, Karp CL, Kirsch DG, Ueno K, Takahashi A, Kastan MB, Griffin DE, Earnshaw WC, Velivona MA and Hardwick JM. (1998). Proc. Natl. Acad. Sci. USA, 95, 554-559.
4. Cory S, Huang DC and Adams JM. (2003). Oncogene, 22, 8590-8607.
5. Craig RW. (2002). Leukemia, 16, 444-454.
6. Degterev A, Lugovskoy A, Cardone M, Mulley B, Wagner G, Mitchison T and Yuan J. (2001). Nat. Cell Biol., 3, 173-182.
7. Derenne S, Monia B, Dean NM, Taylor JK, Rapp MJ, Harousseau JL, Bataille R and Amiot M. (2002). Blood, 100, 194-199.
8. Gomez-Bougie P, Bataille R and Amiot M. (2004). Eur. J. Immunol., 34, 3156-3164.
9. Gomez-Bougie P, Bataille R and Amiot M. (2005). Eur. J. Immunol., 35, 971-976.
10. Gross A, McDonnell JM and Korsmeyer SJ. (1999). Genes Dev., 13, 1899-1911.
11. Herrant M, Jacquel A, Marchetti S, Belhacene N, Colosetti P, Luciano F and Auberger P. (2004). Oncogene, 23, 7863-7873.
12. Huang DC and Strasser A. (2000). Cell, 103, 839-842.
13. Jourdan M, Veyrune JL, Vos JD, Redal N, Couderc G and Klein B. (2003). Oncogene, 22, 2950-2959.
14. Michels J, Johnson and Packham G. (2005). Int. J. Biochem. Cell Biol., 37, 267-271.
15. Michels J, O'Neill JW, Dallman CL, Mouzakiti A, Habens F, Brimmell M, Zhang KY, Craig RW, Marcusson EG, Johnson PW and Packham G. (2004). Oncogene, 23, 4818-4827.
16. Moreau P, Facon T, Attal M, Hulin C, Michallet M, Maloisel F, Sotto JJ, Guilhot F, Marit G, Doyen C, Jaubert J, Fuzibet JG, Francois S, Benboubker L, Monconduit M, Voillat L, Macro M, Berthou C, Dorvaux V, Pignon B, Rio B, Matthes T, Casassus P, Caillot D, Najman N, Grosbois B, Bataille R, Harousseau JL and Intergroupe Francophone du Myelome. (2002). Blood, 99, 731-735.
17. Morishima N, Nakanishi K, Takenouchi H, Shibata T and Yasuhiko Y. (2002). J. Biol. Chem., 277, 34287-34294.
18. O'Connor L, Strasser A, O'Reilly LA, Hausmann G, Adams JM, Cory S and Huang DC. (1998). EMBO J., 17, 384-395.
19. Oliver L, Priault M, Tremblais K, LeCabellec MT, Meflah K, Manon S and Vallette FM. (2000). FEBS Lett., 487, 161-165.
20. Opferman JT, Letai A, Beard C, Sorcinelli MD, Ong CC and Korsmeyer SJ. (2003). Nature, 426, 671-676.
21. Pei XY, Dai Y and Grant S. (2003). Leukemia, 10, 2036-2045.
22. Schmelz K, Wieder T, Tamm I, Muller A, Essmann F, Geilen CC, Schulze-Osthoff K, Dorken B and Daniel PT. (2004). Oncogene, 23, 6743-6759.
23. Snowden RT, Sun XM, Dyer MJ and Cohen GM. (2003). Leukemia, 10, 1981-1989.
24. Tzung SP, Kim KM, Basanez G, Giedt CD, Simon J, Zimmerberg J, Zhang KY and Hockenbery DM. (2001). Nat. Cell Biol., 3, 183-191.
25. von Haefen C, Wieder T, Essmann F, Schulze-Osthoff K, Dorken B and Daniel PT. (2003). Oncogene, 22, 2236-2247.
26. Zhang B, Gojo I and Fenton RG. (2002). Blood, 9, 1885-1893.
27. Zhu Y, Swanson BJ, Wang M, Hildeman DA, Schaefer BC, Liu X, Suzuki H, Mihara K, Kappler J and Marrack P. (2004). Proc. Natl. Acad. Sci. USA, 101, 7681-7686.