메뉴 건너뛰기




Volumn 7, Issue 1, 2012, Pages

Optimal population of FoxP3 + t cells in tumors requires an antigen priming-dependent trafficking receptor switch

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE RECEPTOR CCR7; CHEMOKINE RECEPTOR CCR8; CHEMOKINE RECEPTOR CXCR4; HELIOS ANTIGEN; L SELECTIN; LYMPHOCYTE ANTIGEN; TRANSCRIPTION FACTOR FOXP3; UNCLASSIFIED DRUG; CHEMOKINE RECEPTOR; DNA BINDING PROTEIN; FORKHEAD TRANSCRIPTION FACTOR; FOXP3 PROTEIN, MOUSE; TRANSCRIPTION FACTOR; ZFPN1A2 PROTEIN, MOUSE;

EID: 84856101841     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0030793     Document Type: Article
Times cited : (30)

References (59)
  • 1
    • 39449126502 scopus 로고    scopus 로고
    • The Foxp3+ regulatory T cell: a jack of all trades, master of regulation
    • Tang Q, Bluestone JA, (2008) The Foxp3+ regulatory T cell: a jack of all trades, master of regulation. Nat Immunol 9: 239-244.
    • (2008) Nat Immunol , vol.9 , pp. 239-244
    • Tang, Q.1    Bluestone, J.A.2
  • 2
    • 34548680982 scopus 로고    scopus 로고
    • Foxp3+ regulatory T cells: selfishness under scrutiny
    • Stephens GL, Shevach EM, (2007) Foxp3+ regulatory T cells: selfishness under scrutiny. Immunity 27: 417-419.
    • (2007) Immunity , vol.27 , pp. 417-419
    • Stephens, G.L.1    Shevach, E.M.2
  • 3
    • 34247277666 scopus 로고    scopus 로고
    • Foxp3 in control of the regulatory T cell lineage
    • Zheng Y, Rudensky AY, (2007) Foxp3 in control of the regulatory T cell lineage. Nat Immunol 8: 457-462.
    • (2007) Nat Immunol , vol.8 , pp. 457-462
    • Zheng, Y.1    Rudensky, A.Y.2
  • 4
    • 33947576560 scopus 로고    scopus 로고
    • FOXP3 modifies the phenotypic and functional properties of regulatory T cells
    • Campbell DJ, Ziegler SF, (2007) FOXP3 modifies the phenotypic and functional properties of regulatory T cells. Nat Rev Immunol 7: 305-310.
    • (2007) Nat Rev Immunol , vol.7 , pp. 305-310
    • Campbell, D.J.1    Ziegler, S.F.2
  • 5
    • 33746098905 scopus 로고    scopus 로고
    • Migration and function of FoxP3+ regulatory T cells in the hematolymphoid system
    • Kim CH, (2006) Migration and function of FoxP3+ regulatory T cells in the hematolymphoid system. Exp Hematol 34: 1033-1040.
    • (2006) Exp Hematol , vol.34 , pp. 1033-1040
    • Kim, C.H.1
  • 6
    • 33847415066 scopus 로고    scopus 로고
    • Natural regulatory T cells: mechanisms of suppression
    • Miyara M, Sakaguchi S, (2007) Natural regulatory T cells: mechanisms of suppression. Trends Mol Med 13: 108-116.
    • (2007) Trends Mol Med , vol.13 , pp. 108-116
    • Miyara, M.1    Sakaguchi, S.2
  • 7
    • 33845944537 scopus 로고    scopus 로고
    • FoxP3+ T Cells Undergo Conventional First Switch to Lymphoid Tissue Homing Receptors in Thymus but Accelerated Second Switch to Nonlymphoid Tissue Homing Receptors in Secondary Lymphoid Tissues
    • Lee JH, Kang SG, Kim CH, (2007) FoxP3+ T Cells Undergo Conventional First Switch to Lymphoid Tissue Homing Receptors in Thymus but Accelerated Second Switch to Nonlymphoid Tissue Homing Receptors in Secondary Lymphoid Tissues. J Immunol 178: 301-311.
    • (2007) J Immunol , vol.178 , pp. 301-311
    • Lee, J.H.1    Kang, S.G.2    Kim, C.H.3
  • 8
    • 0024255820 scopus 로고
    • Immunologically mediated regression of a murine lymphoma after treatment with anti-L3T4 antibody. A consequence of removing L3T4+ suppressor T cells from a host generating predominantly Lyt-2+ T cell-mediated immunity
    • Awwad M, North RJ, (1988) Immunologically mediated regression of a murine lymphoma after treatment with anti-L3T4 antibody. A consequence of removing L3T4+ suppressor T cells from a host generating predominantly Lyt-2+ T cell-mediated immunity. J Exp Med 168: 2193-2206.
    • (1988) J Exp Med , vol.168 , pp. 2193-2206
    • Awwad, M.1    North, R.J.2
  • 9
    • 0021248368 scopus 로고
    • Generation and decay of the immune response to a progressive fibrosarcoma. I. Ly-1+2- suppressor T cells down-regulate the generation of Ly-1-2+ effector T cells
    • North RJ, Bursuker I, (1984) Generation and decay of the immune response to a progressive fibrosarcoma. I. Ly-1+2- suppressor T cells down-regulate the generation of Ly-1-2+ effector T cells. J Exp Med 159: 1295-1311.
    • (1984) J Exp Med , vol.159 , pp. 1295-1311
    • North, R.J.1    Bursuker, I.2
  • 10
    • 0020047427 scopus 로고
    • Cyclophosphamide-facilitated adoptive immunotherapy of an established tumor depends on elimination of tumor-induced suppressor T cells
    • North RJ, (1982) Cyclophosphamide-facilitated adoptive immunotherapy of an established tumor depends on elimination of tumor-induced suppressor T cells. J Exp Med 155: 1063-1074.
    • (1982) J Exp Med , vol.155 , pp. 1063-1074
    • North, R.J.1
  • 11
    • 0033168037 scopus 로고    scopus 로고
    • Tumor rejection by in vivo administration of anti-CD25 (interleukin-2 receptor alpha) monoclonal antibody
    • Onizuka S, Tawara I, Shimizu J, Sakaguchi S, Fujita T, et al. (1999) Tumor rejection by in vivo administration of anti-CD25 (interleukin-2 receptor alpha) monoclonal antibody. Cancer Res 59: 3128-3133.
    • (1999) Cancer Res , vol.59 , pp. 3128-3133
    • Onizuka, S.1    Tawara, I.2    Shimizu, J.3    Sakaguchi, S.4    Fujita, T.5
  • 12
    • 0033571105 scopus 로고    scopus 로고
    • Induction of tumor immunity by removing CD25+CD4+ T cells: a common basis between tumor immunity and autoimmunity
    • Shimizu J, Yamazaki S, Sakaguchi S, (1999) Induction of tumor immunity by removing CD25+CD4+ T cells: a common basis between tumor immunity and autoimmunity. J Immunol 163: 5211-5218.
    • (1999) J Immunol , vol.163 , pp. 5211-5218
    • Shimizu, J.1    Yamazaki, S.2    Sakaguchi, S.3
  • 13
    • 34250342883 scopus 로고    scopus 로고
    • The impact of regulatory T cells on carcinogen-induced sarcogenesis
    • Betts G, Twohig J, Van den Broek M, Sierro S, Godkin A, et al. (2007) The impact of regulatory T cells on carcinogen-induced sarcogenesis. Br J Cancer 96: 1849-1854.
    • (2007) Br J Cancer , vol.96 , pp. 1849-1854
    • Betts, G.1    Twohig, J.2    van den Broek, M.3    Sierro, S.4    Godkin, A.5
  • 14
    • 0344153890 scopus 로고    scopus 로고
    • CD4+/CD25+ regulatory cells inhibit activation of tumor-primed CD4+ T cells with IFN-gamma-dependent antiangiogenic activity, as well as long-lasting tumor immunity elicited by peptide vaccination
    • Casares N, Arribillaga L, Sarobe P, Dotor J, Lopez-Diaz de Cerio A, et al. (2003) CD4+/CD25+ regulatory cells inhibit activation of tumor-primed CD4+ T cells with IFN-gamma-dependent antiangiogenic activity, as well as long-lasting tumor immunity elicited by peptide vaccination. J Immunol 171: 5931-5939.
    • (2003) J Immunol , vol.171 , pp. 5931-5939
    • Casares, N.1    Arribillaga, L.2    Sarobe, P.3    Dotor, J.4    de Cerio, A.L.-D.5
  • 15
    • 12244285937 scopus 로고    scopus 로고
    • Regulatory T cells suppress tumor-specific CD8 T cell cytotoxicity through TGF-beta signals in vivo
    • Chen ML, Pittet MJ, Gorelik L, Flavell RA, Weissleder R, et al. (2005) Regulatory T cells suppress tumor-specific CD8 T cell cytotoxicity through TGF-beta signals in vivo. Proc Natl Acad Sci U S A 102: 419-424.
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 419-424
    • Chen, M.L.1    Pittet, M.J.2    Gorelik, L.3    Flavell, R.A.4    Weissleder, R.5
  • 16
    • 4644237613 scopus 로고    scopus 로고
    • Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival
    • Curiel TJ, Coukos G, Zou L, Alvarez X, Cheng P, et al. (2004) Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival. Nat Med 10: 942-949.
    • (2004) Nat Med , vol.10 , pp. 942-949
    • Curiel, T.J.1    Coukos, G.2    Zou, L.3    Alvarez, X.4    Cheng, P.5
  • 17
    • 28544433483 scopus 로고    scopus 로고
    • The expression of the regulatory T cell-specific forkhead box transcription factor FoxP3 is associated with poor prognosis in ovarian cancer
    • Wolf D, Wolf AM, Rumpold H, Fiegl H, Zeimet AG, et al. (2005) The expression of the regulatory T cell-specific forkhead box transcription factor FoxP3 is associated with poor prognosis in ovarian cancer. Clin Cancer Res 11: 8326-8331.
    • (2005) Clin Cancer Res , vol.11 , pp. 8326-8331
    • Wolf, D.1    Wolf, A.M.2    Rumpold, H.3    Fiegl, H.4    Zeimet, A.G.5
  • 18
    • 34247523605 scopus 로고    scopus 로고
    • Tumor-infiltrating Foxp3-CD4+CD25+ T cells predict poor survival in renal cell carcinoma
    • Siddiqui SA, Frigola X, Bonne-Annee S, Mercader M, Kuntz SM, et al. (2007) Tumor-infiltrating Foxp3-CD4+CD25+ T cells predict poor survival in renal cell carcinoma. Clin Cancer Res 13: 2075-2081.
    • (2007) Clin Cancer Res , vol.13 , pp. 2075-2081
    • Siddiqui, S.A.1    Frigola, X.2    Bonne-Annee, S.3    Mercader, M.4    Kuntz, S.M.5
  • 19
    • 20044367117 scopus 로고    scopus 로고
    • Outcome in Hodgkin's lymphoma can be predicted from the presence of accompanying cytotoxic and regulatory T cells
    • Alvaro T, Lejeune M, Salvado MT, Bosch R, Garcia JF, et al. (2005) Outcome in Hodgkin's lymphoma can be predicted from the presence of accompanying cytotoxic and regulatory T cells. Clin Cancer Res 11: 1467-1473.
    • (2005) Clin Cancer Res , vol.11 , pp. 1467-1473
    • Alvaro, T.1    Lejeune, M.2    Salvado, M.T.3    Bosch, R.4    Garcia, J.F.5
  • 20
    • 33751194652 scopus 로고    scopus 로고
    • High numbers of tumor-infiltrating FOXP3-positive regulatory T cells are associated with improved overall survival in follicular lymphoma
    • Carreras J, Lopez-Guillermo A, Fox BC, Colomo L, Martinez A, et al. (2006) High numbers of tumor-infiltrating FOXP3-positive regulatory T cells are associated with improved overall survival in follicular lymphoma. Blood 108: 2957-2964.
    • (2006) Blood , vol.108 , pp. 2957-2964
    • Carreras, J.1    Lopez-Guillermo, A.2    Fox, B.C.3    Colomo, L.4    Martinez, A.5
  • 21
    • 31544455880 scopus 로고    scopus 로고
    • Prognostic value of tumor-infiltrating CD4+ T-cell subpopulations in head and neck cancers
    • Badoual C, Hans S, Rodriguez J, Peyrard S, Klein C, et al. (2006) Prognostic value of tumor-infiltrating CD4+ T-cell subpopulations in head and neck cancers. Clin Cancer Res 12: 465-472.
    • (2006) Clin Cancer Res , vol.12 , pp. 465-472
    • Badoual, C.1    Hans, S.2    Rodriguez, J.3    Peyrard, S.4    Klein, C.5
  • 22
    • 58249089749 scopus 로고    scopus 로고
    • Tumor-infiltrating FOXP3+ T regulatory cells show strong prognostic significance in colorectal cancer
    • Salama P, Phillips M, Grieu F, Morris M, Zeps N, et al. (2009) Tumor-infiltrating FOXP3+ T regulatory cells show strong prognostic significance in colorectal cancer. J Clin Oncol 27: 186-192.
    • (2009) J Clin Oncol , vol.27 , pp. 186-192
    • Salama, P.1    Phillips, M.2    Grieu, F.3    Morris, M.4    Zeps, N.5
  • 23
    • 38049064586 scopus 로고    scopus 로고
    • Localisation pattern of Foxp3+ regulatory T cells is associated with clinical behaviour in gastric cancer
    • Mizukami Y, Kono K, Kawaguchi Y, Akaike H, Kamimura K, et al. (2008) Localisation pattern of Foxp3+ regulatory T cells is associated with clinical behaviour in gastric cancer. Br J Cancer 98: 148-153.
    • (2008) Br J Cancer , vol.98 , pp. 148-153
    • Mizukami, Y.1    Kono, K.2    Kawaguchi, Y.3    Akaike, H.4    Kamimura, K.5
  • 24
    • 62449250053 scopus 로고    scopus 로고
    • Regulatory T cells recruited through CCL22/CCR4 are selectively activated in lymphoid infiltrates surrounding primary breast tumors and lead to an adverse clinical outcome
    • Gobert M, Treilleux I, Bendriss-Vermare N, Bachelot T, Goddard-Leon S, et al. (2009) Regulatory T cells recruited through CCL22/CCR4 are selectively activated in lymphoid infiltrates surrounding primary breast tumors and lead to an adverse clinical outcome. Cancer Res 69: 2000-2009.
    • (2009) Cancer Res , vol.69 , pp. 2000-2009
    • Gobert, M.1    Treilleux, I.2    Bendriss-Vermare, N.3    Bachelot, T.4    Goddard-Leon, S.5
  • 25
    • 44749086828 scopus 로고    scopus 로고
    • Local and systemic induction of CD4+CD25+ regulatory T-cell population by non-Hodgkin lymphoma
    • Mittal S, Marshall NA, Duncan L, Culligan DJ, Barker RN, et al. (2008) Local and systemic induction of CD4+CD25+ regulatory T-cell population by non-Hodgkin lymphoma. Blood 111: 5359-5370.
    • (2008) Blood , vol.111 , pp. 5359-5370
    • Mittal, S.1    Marshall, N.A.2    Duncan, L.3    Culligan, D.J.4    Barker, R.N.5
  • 26
    • 34250198303 scopus 로고    scopus 로고
    • Melanoma induces immunosuppression by up-regulating FOXP3(+) regulatory T cells
    • Baumgartner J, Wilson C, Palmer B, Richter D, Banerjee A, et al. (2007) Melanoma induces immunosuppression by up-regulating FOXP3(+) regulatory T cells. J Surg Res 141: 72-77.
    • (2007) J Surg Res , vol.141 , pp. 72-77
    • Baumgartner, J.1    Wilson, C.2    Palmer, B.3    Richter, D.4    Banerjee, A.5
  • 27
    • 33847337912 scopus 로고    scopus 로고
    • Tumor evasion of the immune system by converting CD4+CD25- T cells into CD4+CD25+ T regulatory cells: role of tumor-derived TGF-beta
    • Liu VC, Wong LY, Jang T, Shah AH, Park I, et al. (2007) Tumor evasion of the immune system by converting CD4+CD25- T cells into CD4+CD25+ T regulatory cells: role of tumor-derived TGF-beta. J Immunol 178: 2883-2892.
    • (2007) J Immunol , vol.178 , pp. 2883-2892
    • Liu, V.C.1    Wong, L.Y.2    Jang, T.3    Shah, A.H.4    Park, I.5
  • 28
    • 20444464066 scopus 로고    scopus 로고
    • Tumor cyclooxygenase-2/prostaglandin E2-dependent promotion of FOXP3 expression and CD4+ CD25+ T regulatory cell activities in lung cancer
    • Sharma S, Yang SC, Zhu L, Reckamp K, Gardner B, et al. (2005) Tumor cyclooxygenase-2/prostaglandin E2-dependent promotion of FOXP3 expression and CD4+ CD25+ T regulatory cell activities in lung cancer. Cancer Res 65: 5211-5220.
    • (2005) Cancer Res , vol.65 , pp. 5211-5220
    • Sharma, S.1    Yang, S.C.2    Zhu, L.3    Reckamp, K.4    Gardner, B.5
  • 29
    • 44449101245 scopus 로고    scopus 로고
    • Tumor-induced impairment of TCR signaling results in compromised functionality of tumor-infiltrating regulatory T cells
    • Lutsiak ME, Tagaya Y, Adams AJ, Schlom J, Sabzevari H, (2008) Tumor-induced impairment of TCR signaling results in compromised functionality of tumor-infiltrating regulatory T cells. J Immunol 180: 5871-5881.
    • (2008) J Immunol , vol.180 , pp. 5871-5881
    • Lutsiak, M.E.1    Tagaya, Y.2    Adams, A.J.3    Schlom, J.4    Sabzevari, H.5
  • 30
    • 79957815661 scopus 로고    scopus 로고
    • In situ prior proliferation of CD4+ CCR6+ regulatory T cells facilitated by TGF-beta secreting DCs is crucial for their enrichment and suppression in tumor immunity
    • Xu L, Xu W, Wen Z, Xiong S, (2011) In situ prior proliferation of CD4+ CCR6+ regulatory T cells facilitated by TGF-beta secreting DCs is crucial for their enrichment and suppression in tumor immunity. PLoS One 6: e20282.
    • (2011) PLoS One , vol.6
    • Xu, L.1    Xu, W.2    Wen, Z.3    Xiong, S.4
  • 31
    • 69049107358 scopus 로고    scopus 로고
    • Instability of the transcription factor Foxp3 leads to the generation of pathogenic memory T cells in vivo
    • Zhou X, Bailey-Bucktrout SL, Jeker LT, Penaranda C, Martinez-Llordella M, et al. (2009) Instability of the transcription factor Foxp3 leads to the generation of pathogenic memory T cells in vivo. Nat Immunol 10: 1000-1007.
    • (2009) Nat Immunol , vol.10 , pp. 1000-1007
    • Zhou, X.1    Bailey-Bucktrout, S.L.2    Jeker, L.T.3    Penaranda, C.4    Martinez-Llordella, M.5
  • 32
    • 0023821578 scopus 로고
    • Introduction of soluble protein into the class I pathway of antigen processing and presentation
    • Moore MW, Carbone FR, Bevan MJ, (1988) Introduction of soluble protein into the class I pathway of antigen processing and presentation. Cell 54: 777-785.
    • (1988) Cell , vol.54 , pp. 777-785
    • Moore, M.W.1    Carbone, F.R.2    Bevan, M.J.3
  • 33
    • 77954730539 scopus 로고    scopus 로고
    • Retinoic acid determines the precise tissue tropism of inflammatory Th17 cells in the intestine
    • Wang C, Kang SG, HogenEsch H, Love PE, Kim CH, (2010) Retinoic acid determines the precise tissue tropism of inflammatory Th17 cells in the intestine. J Immunol 184: 5519-5526.
    • (2010) J Immunol , vol.184 , pp. 5519-5526
    • Wang, C.1    Kang, S.G.2    HogenEsch, H.3    Love, P.E.4    Kim, C.H.5
  • 34
    • 58849152515 scopus 로고    scopus 로고
    • The roles of CCR6 in migration of Th17 cells and regulation of effector T-cell balance in the gut
    • Wang C, Kang SG, Lee J, Sun Z, Kim CH, (2009) The roles of CCR6 in migration of Th17 cells and regulation of effector T-cell balance in the gut. Mucosal Immunol 2: 173-183.
    • (2009) Mucosal Immunol , vol.2 , pp. 173-183
    • Wang, C.1    Kang, S.G.2    Lee, J.3    Sun, Z.4    Kim, C.H.5
  • 35
    • 77951638740 scopus 로고    scopus 로고
    • Expression of Helios, an Ikaros transcription factor family member, differentiates thymic-derived from peripherally induced Foxp3+ T regulatory cells
    • Thornton AM, Korty PE, Tran DQ, Wohlfert EA, Murray PE, et al. (2010) Expression of Helios, an Ikaros transcription factor family member, differentiates thymic-derived from peripherally induced Foxp3+ T regulatory cells. J Immunol 184: 3433-3441.
    • (2010) J Immunol , vol.184 , pp. 3433-3441
    • Thornton, A.M.1    Korty, P.E.2    Tran, D.Q.3    Wohlfert, E.A.4    Murray, P.E.5
  • 37
    • 84862943660 scopus 로고    scopus 로고
    • FoxP3+ T cells undergo conventional first switch to lymphoid tissue homing receptors in thymus but accelerated second switch to non-lymphoid tissue homing receptors in secondary lymphoid tissues
    • Lee J, Kang SG, Kim CH, (2006) FoxP3+ T cells undergo conventional first switch to lymphoid tissue homing receptors in thymus but accelerated second switch to non-lymphoid tissue homing receptors in secondary lymphoid tissues. J Immunol Pending.
    • (2006) J Immunol Pending
    • Lee, J.1    Kang, S.G.2    Kim, C.H.3
  • 38
    • 33646168597 scopus 로고    scopus 로고
    • FOXP3: of mice and men
    • Ziegler SF, (2006) FOXP3: of mice and men. Annu Rev Immunol 24: 209-226.
    • (2006) Annu Rev Immunol , vol.24 , pp. 209-226
    • Ziegler, S.F.1
  • 39
    • 77952513877 scopus 로고    scopus 로고
    • FOXP3 and its role in the immune system
    • Kim CH, (2009) FOXP3 and its role in the immune system. Adv Exp Med Biol 665: 17-29.
    • (2009) Adv Exp Med Biol , vol.665 , pp. 17-29
    • Kim, C.H.1
  • 40
    • 51049101255 scopus 로고    scopus 로고
    • CD4+ FoxP3+ regulatory T cells confer infectious tolerance in a TGF-beta-dependent manner
    • Andersson J, Tran DQ, Pesu M, Davidson TS, Ramsey H, et al. (2008) CD4+ FoxP3+ regulatory T cells confer infectious tolerance in a TGF-beta-dependent manner. J Exp Med 205: 1975-1981.
    • (2008) J Exp Med , vol.205 , pp. 1975-1981
    • Andersson, J.1    Tran, D.Q.2    Pesu, M.3    Davidson, T.S.4    Ramsey, H.5
  • 41
    • 36549030784 scopus 로고    scopus 로고
    • The inhibitory cytokine IL-35 contributes to regulatory T-cell function
    • Collison LW, Workman CJ, Kuo TT, Boyd K, Wang Y, et al. (2007) The inhibitory cytokine IL-35 contributes to regulatory T-cell function. Nature 450: 566-569.
    • (2007) Nature , vol.450 , pp. 566-569
    • Collison, L.W.1    Workman, C.J.2    Kuo, T.T.3    Boyd, K.4    Wang, Y.5
  • 42
    • 77954721060 scopus 로고    scopus 로고
    • Regulatory T cells in tumor immunity
    • Nishikawa H, Sakaguchi S, (2010) Regulatory T cells in tumor immunity. Int J Cancer 127: 759-767.
    • (2010) Int J Cancer , vol.127 , pp. 759-767
    • Nishikawa, H.1    Sakaguchi, S.2
  • 43
    • 64849098858 scopus 로고    scopus 로고
    • NK-dependent increases in CCL22 secretion selectively recruits regulatory T cells to the tumor microenvironment
    • Mailloux AW, Young MR, (2009) NK-dependent increases in CCL22 secretion selectively recruits regulatory T cells to the tumor microenvironment. J Immunol 182: 2753-2765.
    • (2009) J Immunol , vol.182 , pp. 2753-2765
    • Mailloux, A.W.1    Young, M.R.2
  • 44
    • 63149148047 scopus 로고    scopus 로고
    • Disruption of CCR5-dependent homing of regulatory T cells inhibits tumor growth in a murine model of pancreatic cancer
    • Tan MC, Goedegebuure PS, Belt BA, Flaherty B, Sankpal N, et al. (2009) Disruption of CCR5-dependent homing of regulatory T cells inhibits tumor growth in a murine model of pancreatic cancer. J Immunol 182: 1746-1755.
    • (2009) J Immunol , vol.182 , pp. 1746-1755
    • Tan, M.C.1    Goedegebuure, P.S.2    Belt, B.A.3    Flaherty, B.4    Sankpal, N.5
  • 45
    • 42149152160 scopus 로고    scopus 로고
    • CCL17 and CCL22 chemokines within tumor microenvironment are related to accumulation of Foxp3+ regulatory T cells in gastric cancer
    • Mizukami Y, Kono K, Kawaguchi Y, Akaike H, Kamimura K, et al. (2008) CCL17 and CCL22 chemokines within tumor microenvironment are related to accumulation of Foxp3+ regulatory T cells in gastric cancer. Int J Cancer 122: 2286-2293.
    • (2008) Int J Cancer , vol.122 , pp. 2286-2293
    • Mizukami, Y.1    Kono, K.2    Kawaguchi, Y.3    Akaike, H.4    Kamimura, K.5
  • 46
    • 33745261751 scopus 로고    scopus 로고
    • Specific recruitment of CC chemokine receptor 4-positive regulatory T cells in Hodgkin lymphoma fosters immune privilege
    • Ishida T, Ishii T, Inagaki A, Yano H, Komatsu H, et al. (2006) Specific recruitment of CC chemokine receptor 4-positive regulatory T cells in Hodgkin lymphoma fosters immune privilege. Cancer Res 66: 5716-5722.
    • (2006) Cancer Res , vol.66 , pp. 5716-5722
    • Ishida, T.1    Ishii, T.2    Inagaki, A.3    Yano, H.4    Komatsu, H.5
  • 47
    • 33646239606 scopus 로고    scopus 로고
    • Tumor-induced expansion of regulatory T cells by conversion of CD4+CD25- lymphocytes is thymus and proliferation independent
    • Valzasina B, Piconese S, Guiducci C, Colombo MP, (2006) Tumor-induced expansion of regulatory T cells by conversion of CD4+CD25- lymphocytes is thymus and proliferation independent. Cancer Res 66: 4488-4495.
    • (2006) Cancer Res , vol.66 , pp. 4488-4495
    • Valzasina, B.1    Piconese, S.2    Guiducci, C.3    Colombo, M.P.4
  • 48
    • 65549158084 scopus 로고    scopus 로고
    • Tumor-derived TGF-beta mediates conversion of CD4+Foxp3+ regulatory T cells in a murine model of pancreas cancer
    • Moo-Young TA, Larson JW, Belt BA, Tan MC, Hawkins WG, et al. (2009) Tumor-derived TGF-beta mediates conversion of CD4+Foxp3+ regulatory T cells in a murine model of pancreas cancer. J Immunother 32: 12-21.
    • (2009) J Immunother , vol.32 , pp. 12-21
    • Moo-Young, T.A.1    Larson, J.W.2    Belt, B.A.3    Tan, M.C.4    Hawkins, W.G.5
  • 49
    • 0348223787 scopus 로고    scopus 로고
    • Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory T cells by TGF-beta induction of transcription factor Foxp3
    • Chen W, Jin W, Hardegen N, Lei KJ, Li L, et al. (2003) Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory T cells by TGF-beta induction of transcription factor Foxp3. J Exp Med 198: 1875-1886.
    • (2003) J Exp Med , vol.198 , pp. 1875-1886
    • Chen, W.1    Jin, W.2    Hardegen, N.3    Lei, K.J.4    Li, L.5
  • 50
  • 51
    • 34447503805 scopus 로고    scopus 로고
    • Reciprocal TH17 and regulatory T cell differentiation mediated by retinoic acid
    • Mucida D, Park Y, Kim G, Turovskaya O, Scott I, et al. (2007) Reciprocal TH17 and regulatory T cell differentiation mediated by retinoic acid. Science 317: 256-260.
    • (2007) Science , vol.317 , pp. 256-260
    • Mucida, D.1    Park, Y.2    Kim, G.3    Turovskaya, O.4    Scott, I.5
  • 52
    • 22544436066 scopus 로고    scopus 로고
    • Prostaglandin E2 induces FOXP3 gene expression and T regulatory cell function in human CD4+ T cells
    • Baratelli F, Lin Y, Zhu L, Yang SC, Heuze-Vourc'h N, et al. (2005) Prostaglandin E2 induces FOXP3 gene expression and T regulatory cell function in human CD4+ T cells. J Immunol 175: 1483-1490.
    • (2005) J Immunol , vol.175 , pp. 1483-1490
    • Baratelli, F.1    Lin, Y.2    Zhu, L.3    Yang, S.C.4    Heuze-Vourc'h, N.5
  • 53
    • 80051946730 scopus 로고    scopus 로고
    • Progesterone promotes differentiation of human cord blood fetal T cells into T regulatory cells but suppresses their differentiation into th17 cells
    • Lee JH, Ulrich B, Cho J, Park J, Kim CH, (2011) Progesterone promotes differentiation of human cord blood fetal T cells into T regulatory cells but suppresses their differentiation into th17 cells. J Immunol 187: 1778-1787.
    • (2011) J Immunol , vol.187 , pp. 1778-1787
    • Lee, J.H.1    Ulrich, B.2    Cho, J.3    Park, J.4    Kim, C.H.5
  • 54
    • 55249095393 scopus 로고    scopus 로고
    • Hypoxia controls CD4+CD25+ regulatory T-cell homeostasis via hypoxia-inducible factor-1alpha
    • Ben-Shoshan J, Maysel-Auslender S, Mor A, Keren G, George J, (2008) Hypoxia controls CD4+CD25+ regulatory T-cell homeostasis via hypoxia-inducible factor-1alpha. Eur J Immunol 38: 2412-2418.
    • (2008) Eur J Immunol , vol.38 , pp. 2412-2418
    • Ben-Shoshan, J.1    Maysel-Auslender, S.2    Mor, A.3    Keren, G.4    George, J.5
  • 55
    • 80052277906 scopus 로고    scopus 로고
    • Control of T(H)17/T(reg) Balance by Hypoxia-Inducible Factor 1
    • Dang EV, Barbi J, Yang HY, Jinasena D, Yu H, et al. (2011) Control of T(H)17/T(reg) Balance by Hypoxia-Inducible Factor 1. Cell 146: 772-784.
    • (2011) Cell , vol.146 , pp. 772-784
    • Dang, E.V.1    Barbi, J.2    Yang, H.Y.3    Jinasena, D.4    Yu, H.5
  • 56
    • 79960369458 scopus 로고    scopus 로고
    • HIF1alpha-dependent glycolytic pathway orchestrates a metabolic checkpoint for the differentiation of TH17 and Treg cells
    • Shi LZ, Wang R, Huang G, Vogel P, Neale G, et al. (2011) HIF1alpha-dependent glycolytic pathway orchestrates a metabolic checkpoint for the differentiation of TH17 and Treg cells. J Exp Med 208: 1367-1376.
    • (2011) J Exp Med , vol.208 , pp. 1367-1376
    • Shi, L.Z.1    Wang, R.2    Huang, G.3    Vogel, P.4    Neale, G.5
  • 57
    • 80051801789 scopus 로고    scopus 로고
    • Expanded subpopulation of FoxP3(+) T regulatory cells in renal cell carcinoma co-express Helios, indicating they could be derived from natural but not induced Tregs
    • Elkord E, Sharma S, Burt DJ, Hawkins RE, (2011) Expanded subpopulation of FoxP3(+) T regulatory cells in renal cell carcinoma co-express Helios, indicating they could be derived from natural but not induced Tregs. Clin Immunol 140: 218-222.
    • (2011) Clin Immunol , vol.140 , pp. 218-222
    • Elkord, E.1    Sharma, S.2    Burt, D.J.3    Hawkins, R.E.4
  • 58
    • 33750795581 scopus 로고    scopus 로고
    • CD4+CXCR4highCD69+ T cells accumulate in lung adenocarcinoma
    • Wald O, Izhar U, Amir G, Avniel S, Bar-Shavit Y, et al. (2006) CD4+CXCR4highCD69+ T cells accumulate in lung adenocarcinoma. J Immunol 177: 6983-6990.
    • (2006) J Immunol , vol.177 , pp. 6983-6990
    • Wald, O.1    Izhar, U.2    Amir, G.3    Avniel, S.4    Bar-Shavit, Y.5
  • 59
    • 23044472074 scopus 로고    scopus 로고
    • The greater chemotactic network for lymphocyte trafficking: chemokines and beyond
    • Kim CH, (2005) The greater chemotactic network for lymphocyte trafficking: chemokines and beyond. Curr Opin Hematol 12: 298-304.
    • (2005) Curr Opin Hematol , vol.12 , pp. 298-304
    • Kim, C.H.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.