2-amino-3-methylimidazo[4,5-f]quinoline (iq) promotes mouse hepatocarcinogenesis by activating transforming growth factor-β and Wnt/β-catenin signaling pathways

Toxicological Sciences

Volumn 125, Issue 2, 2012, Pages 392-400

  Xie, Xiao Li ^a   Wei, Min ^a   Kakehashi, Anna ^a   Yamano, Shotaro ^a   Tajiri, Masaki ^a   Wanibuchi, Hideki ^a  

^a OSAKA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

E cadherin; Hepatocarcinogenesis; IQ; TGF pathway; Wnt catenin pathway

Indexed keywords

2 AMINO 3 METHYLIMIDAZO[4,5 F]QUINOLINE; BETA CATENIN; CYCLIN D1; CYCLIN DEPENDENT KINASE INHIBITOR 1; MYC PROTEIN; PROTEIN C JUN; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 1; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 2; UVOMORULIN; WNT PROTEIN; WNT1 PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BASOPHILIA; CELL MEMBRANE; CELL NUCLEUS; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOPLASM; EOSINOPHILIA; LIVER ADENOMA; LIVER CARCINOGENESIS; LIVER CELL CARCINOMA; MALE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RAT; SIGNAL TRANSDUCTION; UPREGULATION;

MUS;

EID: 84856090878     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfr314     Document Type: Article

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