N-demethylation is a major route of 2-amino-3-methylimidazo[4,5-f]quinoline metabolism in mouse

Drug Metabolism and Disposition

Volumn 36, Issue 6, 2008, Pages 1143-1152

  Lakshmi, Vijaya M ^a,b   Fong, Fu Hsu ^c   Zenser, Terry V ^a,b  

^a VETERANS AFFAIRS MEDICAL CENTER   (United States)

^b SAINT LOUIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 AMINO 3 METHYLIMIDAZO [4,5 F] QUINOLINE; 5 O GLUCURONIDE; 5 SULFATE; DRUG METABOLITE; ELLIPTICINE; ETHOXYRESORUFIN DEETHYLASE; GLUCURONIDE; N DEMETHYLASE; QUINOLINE DERIVATIVE; SULFAMIC ACID;

ANIMAL TISSUE; ARTICLE; CARCINOGENICITY; CONTROLLED STUDY; DRUG METABOLISM; DRUG URINE LEVEL; ELECTROSPRAY MASS SPECTROMETRY; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MOUSE; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; CARCINOGENS; FEMALE; LIVER; MICE; MICE, INBRED C57BL; MICROSOMES, LIVER; QUINOLINES; RATS; RATS, INBRED F344;

MUS; RATTUS; RODENTIA;

EID: 44149110917     PISSN: 00909556     EISSN: 1521009X     Source Type: Journal    
DOI: 10.1124/dmd.107.019166     Document Type: Article

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