Identification and functional characterization of a primate-specific E2F1 binding motif regulating MCPH1 expression

FEBS Journal

Volumn 279, Issue 3, 2012, Pages 491-503

  Shi, Lei ^a,b   Su, Bing ^a  

^a KUNMING INSTITUTE OF ZOOLOGY   (China)

^b UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

Author keywords

E2F1; evolution; gene regulation; MCPH1; primates; promoter activity

Indexed keywords

BRAIN PROTEIN; MESSENGER RNA; MICROCEPHALIN PROTEIN; TRANSCRIPTION FACTOR E2F1; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; CONTROLLED STUDY; E2F1 GENE; ELECTROPHORETIC MOBILITY; GENE; GENE DELETION; GENE EXPRESSION REGULATION; GENE FUNCTION; GENE INTERACTION; GENE LOCATION; GENE MAPPING; GENE OVEREXPRESSION; GENE SILENCING; GENE STRUCTURE; INHIBITION KINETICS; MICROCEPHALIN GENE; MOLECULAR CLONING; MOLECULAR EVOLUTION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIMATE; PRIORITY JOURNAL; PROMOTER REGION; SEQUENCE ANALYSIS; TRANSACTIVATION; TRANSCRIPTION INITIATION SITE; UPREGULATION;

AMINO ACID MOTIFS; ANIMALS; BASE SEQUENCE; BINDING SITES; CELL CYCLE CHECKPOINTS; CLONING, MOLECULAR; E2F1 TRANSCRIPTION FACTOR; EVOLUTION, MOLECULAR; HUMANS; MACACA MULATTA; MOLECULAR SEQUENCE DATA; NERVE TISSUE PROTEINS; PAN TROGLODYTES; PRIMATES; PROMOTER REGIONS, GENETIC; TRANSCRIPTION, GENETIC;

PRIMATES; VERTEBRATA;

EID: 84856086311     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/j.1742-4658.2011.08441.x     Document Type: Article

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