-
1
-
-
79951558318
-
National, regional, and global trends in body-mass index since 1980: Systematic analysis of health examination surveys and epidemiological studies with 960 country-years and 9.1 million participants
-
Finucane MM, Stevens GA, Cowan MJ, Danaei G, Lin JK, Paciorek CJ, Singh GM, Gutierrez HR, Lu Y, Bahalim AN, et al. National, regional, and global trends in body-mass index since 1980: systematic analysis of health examination surveys and epidemiological studies with 960 country-years and 9.1 million participants. Lancet 2011. 377:557-567.
-
(2011)
Lancet
, vol.377
, pp. 557-567
-
-
Finucane, M.M.1
Stevens, G.A.2
Cowan, M.J.3
Danaei, G.4
Lin, J.K.5
Paciorek, C.J.6
Singh, G.M.7
Gutierrez, H.R.8
Lu, Y.9
Bahalim, A.N.10
-
2
-
-
84855991318
-
-
WHO. Obesity and overweight
-
WHO. Obesity and overweight. http://www.who.int/mediacentre/factsheets/fs311/en/index.html, 2011.
-
(2011)
-
-
-
3
-
-
21844445860
-
Long-term non-pharmacologic weight loss interventions for adults with type 2 diabetes
-
Norris SL, Zhang X, Avenell A, Gregg E, Brown TJ, Schmid CH, Lau J. Long-term non-pharmacologic weight loss interventions for adults with type 2 diabetes. Cochrane Database Syst Rev 2005. 2:CD004095.
-
(2005)
Cochrane Database Syst Rev
, vol.2
-
-
Norris, S.L.1
Zhang, X.2
Avenell, A.3
Gregg, E.4
Brown, T.J.5
Schmid, C.H.6
Lau, J.7
-
4
-
-
34648836960
-
Weight-loss outcomes: A systematic review and meta-analysis of weight-loss clinical trials with a minimum 1-year followup
-
Franz MJ, VanWormer JJ, Crain AL, Boucher JL, Histon T, Caplan W, Bowman JD, Pronk NP. Weight-loss outcomes: a systematic review and meta-analysis of weight-loss clinical trials with a minimum 1-year followup. J Am Diet Assoc 2007. 107:1755-1767.
-
(2007)
J Am Diet Assoc
, vol.107
, pp. 1755-1767
-
-
Franz, M.J.1
Vanwormer, J.J.2
Crain, A.L.3
Boucher, J.L.4
Histon, T.5
Caplan, W.6
Bowman, J.D.7
Pronk, N.P.8
-
5
-
-
79959203897
-
Interventions promoting physical activity among obese populations: A meta-analysis considering global effect, long-term maintenance, physical activity indicators and dose characteristics
-
Gourlan MJ, Trouilloud DO, Sarrazin PG. Interventions promoting physical activity among obese populations: a meta-analysis considering global effect, long-term maintenance, physical activity indicators and dose characteristics. Obes Rev 2011. 12:E633-E645.
-
(2011)
Obes Rev
, vol.12
-
-
Gourlan, M.J.1
Trouilloud, D.O.2
Sarrazin, P.G.3
-
7
-
-
37249083878
-
Long term pharmacotherapy for obesity and overweight: Updated meta-analysis
-
Rucker D, Padwal R, Li SK, Curioni C, Lau DC. Long term pharmacotherapy for obesity and overweight: updated meta-analysis. BMJ 2007. 335:1194-1199.
-
(2007)
BMJ
, vol.335
, pp. 1194-1199
-
-
Rucker, D.1
Padwal, R.2
Li, S.K.3
Curioni, C.4
Lau, D.C.5
-
8
-
-
70849093104
-
Pharmacotherapy for obesity
-
Li M, Cheung BM. Pharmacotherapy for obesity. Br J Clin Pharmacol 2009. 68:804-810.
-
(2009)
Br J Clin Pharmacol
, vol.68
, pp. 804-810
-
-
Li, M.1
Cheung, B.M.2
-
9
-
-
53849093386
-
Industry funding and the reporting quality of large long-term weight loss trials
-
Thomas O, Thabane L, Douketis J, Chu R, Westfall AO, Allison DB. Industry funding and the reporting quality of large long-term weight loss trials. Int J Obes (Lond) 2008. 32:1531-1536.
-
(2008)
Int J Obes (Lond)
, vol.32
, pp. 1531-1536
-
-
Thomas, O.1
Thabane, L.2
Douketis, J.3
Chu, R.4
Westfall, A.O.5
Allison, D.B.6
-
10
-
-
79957988002
-
Bariatric surgery: A systematic review and network meta-analysis of randomized trials
-
Padwal R, Klarenbach S, Wiebe N, Birch D, Karmali S, Manns B, Hazel M, Sharma AM, Tonelli M. Bariatric surgery: a systematic review and network meta-analysis of randomized trials. Obes Rev 2011. 12(8):602-621.
-
(2011)
Obes Rev
, vol.12
, Issue.8
, pp. 602-621
-
-
Padwal, R.1
Klarenbach, S.2
Wiebe, N.3
Birch, D.4
Karmali, S.5
Manns, B.6
Hazel, M.7
Sharma, A.M.8
Tonelli, M.9
-
11
-
-
79951678085
-
Long-term prevention of mortality in morbid obesity through bariatric surgery. a systematic review and meta-analysis of trials performed with gastric banding and gastric bypass
-
Pontiroli AE, Morabito A. Long-term prevention of mortality in morbid obesity through bariatric surgery. a systematic review and meta-analysis of trials performed with gastric banding and gastric bypass. Ann Surg 2011. 253:484-487.
-
(2011)
Ann Surg
, vol.253
, pp. 484-487
-
-
Pontiroli, A.E.1
Morabito, A.2
-
12
-
-
0034917709
-
Impact of overweight on the risk of developing common chronic diseases during a 10-year period
-
Field AE, Coakley EH, Must A, Spadano JL, Laird N, Dietz WH, Rimm E, Colditz GA. Impact of overweight on the risk of developing common chronic diseases during a 10-year period. Arch Intern Med 2001. 161:1581-1586.
-
(2001)
Arch Intern Med
, vol.161
, pp. 1581-1586
-
-
Field, A.E.1
Coakley, E.H.2
Must, A.3
Spadano, J.L.4
Laird, N.5
Dietz, W.H.6
Rimm, E.7
Colditz, G.A.8
-
13
-
-
0030855615
-
Weight change and diabetes incidence: Findings from a national cohort of US adults
-
Ford ES, Williamson DF, Liu S. Weight change and diabetes incidence: findings from a national cohort of US adults. Am J Epidemiol 1997. 146:214-222.
-
(1997)
Am J Epidemiol
, vol.146
, pp. 214-222
-
-
Ford, E.S.1
Williamson, D.F.2
Liu, S.3
-
14
-
-
34548609993
-
Systematic review: Comparative effectiveness and safety of oral medications for type 2 diabetes mellitus
-
Bolen S, Feldman L, Vassy J, Wilson L, Yeh H-C, Marinopoulos S, Wiley C, Selvin E, Wilson R, Bass EB, et al. Systematic review: comparative effectiveness and safety of oral medications for type 2 diabetes mellitus. Ann Intern Med 2007. 147:386-399.
-
(2007)
Ann Intern Med
, vol.147
, pp. 386-399
-
-
Bolen, S.1
Feldman, L.2
Vassy, J.3
Wilson, L.4
Yeh, H.-C.5
Marinopoulos, S.6
Wiley, C.7
Selvin, E.8
Wilson, R.9
Bass, E.B.10
-
15
-
-
84855991313
-
Effects of glucagon-like peptide-1 receptor agonists on weight loss: Systematic review and meta-analyses of randomised controlled trials
-
In press
-
Vilsboll T, Christensen M, Junker A, Knop FK, Gluud LL. Effects of glucagon-like peptide-1 receptor agonists on weight loss: systematic review and meta-analyses of randomised controlled trials. BMJ 2011. In press.
-
(2011)
BMJ
-
-
Vilsboll, T.1
Christensen, M.2
Junker, A.3
Knop, F.K.4
Gluud, L.L.5
-
16
-
-
0027227370
-
Glucagon-like peptide-1 (7-36)amide and glucose-dependent insulinotropic polypeptide secretion in response to nutrient ingestion in man: Acute post-prandial and 24-h secretion patterns
-
Elliott RM, Morgan LM, Tredger JA, Deacon S, Wright J, Marks V. Glucagon-like peptide-1 (7-36)amide and glucose-dependent insulinotropic polypeptide secretion in response to nutrient ingestion in man: acute post-prandial and 24-h secretion patterns. J Endocrinol 1993. 138:159-166.
-
(1993)
J Endocrinol
, vol.138
, pp. 159-166
-
-
Elliott, R.M.1
Morgan, L.M.2
Tredger, J.A.3
Deacon, S.4
Wright, J.5
Marks, V.6
-
17
-
-
0028953577
-
Degradation of glucagon-like peptide-1 by human plasma in vitro yields an Nterminally truncated peptide that is a major endogenous metabolite in vivo
-
Deacon CF, Johnsen AH, Holst JJ. Degradation of glucagon-like peptide-1 by human plasma in vitro yields an Nterminally truncated peptide that is a major endogenous metabolite in vivo. J Clin Endocrinol Metab 1995. 80:952-957.
-
(1995)
J Clin Endocrinol Metab
, vol.80
, pp. 952-957
-
-
Deacon, C.F.1
Johnsen, A.H.2
Holst, J.J.3
-
18
-
-
0037241085
-
Similar elimination rates of glucagon-like peptide-1 in obese type 2 diabetic patients and healthy subjects
-
Vilsboll T, Agerso H, Krarup T, Holst JJ. Similar elimination rates of glucagon-like peptide-1 in obese type 2 diabetic patients and healthy subjects. J Clin Endocrinol Metab 2003. 88:220-224.
-
(2003)
J Clin Endocrinol Metab
, vol.88
, pp. 220-224
-
-
Vilsboll, T.1
Agerso, H.2
Krarup, T.3
Holst, J.J.4
-
19
-
-
0028867442
-
Distribution of GLP-1 binding sites in the rat brain: Evidence that exendin-4 is a ligand of brain GLP-1 binding sites
-
Göke R, Larsen PJ, Mikkelsen JD, Sheikh SP. Distribution of GLP-1 binding sites in the rat brain: evidence that exendin-4 is a ligand of brain GLP-1 binding sites. Eur J Neurosci 1995. 7:2294-2300.
-
(1995)
Eur J Neurosci
, vol.7
, pp. 2294-2300
-
-
Göke, R.1
Larsen, P.J.2
Mikkelsen, J.D.3
Sheikh, S.P.4
-
20
-
-
63849248275
-
Evidence that intestinal glucagon-like peptide-1 plays a physiological role in satiety
-
Williams DL, Baskin DG, Schwartz MW. Evidence that intestinal glucagon-like peptide-1 plays a physiological role in satiety. Endocrinology 2009. 150:1680-1687.
-
(2009)
Endocrinology
, vol.150
, pp. 1680-1687
-
-
Williams, D.L.1
Baskin, D.G.2
Schwartz, M.W.3
-
21
-
-
13344282056
-
A role for glucagon-like peptide-1 in the central regulation of feeding
-
Turton MD, O'Shea D, Gunn I, Beak SA, Edwards CM, Meeran K, Choi SJ, Taylor GM, Heath MM, Lambert PD, et al. A role for glucagon-like peptide-1 in the central regulation of feeding. Nature 1996. 379:69-72.
-
(1996)
Nature
, vol.379
, pp. 69-72
-
-
Turton, M.D.1
O'Shea, D.2
Gunn, I.3
Beak, S.A.4
Edwards, C.M.5
Meeran, K.6
Choi, S.J.7
Taylor, G.M.8
Heath, M.M.9
Lambert, P.D.10
-
22
-
-
12244268666
-
On the physiology of GIP and GLP-1
-
Holst JJ. On the physiology of GIP and GLP-1. Horm Metab Res 2004. 36:747-754.
-
(2004)
Horm Metab Res
, vol.36
, pp. 747-754
-
-
Holst, J.J.1
-
23
-
-
34547951456
-
Liraglutide, a oncedaily human glucagon-like peptide-1 analog, minimizes food intake in severely obese minipigs
-
Raun K, von Voss P, Knudsen LB. Liraglutide, a oncedaily human glucagon-like peptide-1 analog, minimizes food intake in severely obese minipigs. Obesity (Silver Spring) 2007. 15:1710-1716.
-
(2007)
Obesity (Silver Spring)
, vol.15
, pp. 1710-1716
-
-
Raun, K.1
von Voss, P.2
Knudsen, L.B.3
-
24
-
-
0029859220
-
Central administration of GLP-1-(7-36) amide inhibits food and water intake in rats
-
Tang-Christensen M, Larsen PJ, Göke R, Fink-Jensen A, Jessop DS, Moller M, Sheikh SP. Central administration of GLP-1-(7-36) amide inhibits food and water intake in rats. Am J Physiol 1996. 271:R848-R856.
-
(1996)
Am J Physiol
, vol.271
-
-
Tang-Christensen, M.1
Larsen, P.J.2
Göke, R.3
Fink-Jensen, A.4
Jessop, D.S.5
Moller, M.6
Sheikh, S.P.7
-
25
-
-
34247639607
-
Characterization of brainstem preproglucagon projections to the paraventricular and dorsomedial hypothalamic nuclei
-
Vrang N, Hansen M, Larsen PJ, Tang-Christensen M. Characterization of brainstem preproglucagon projections to the paraventricular and dorsomedial hypothalamic nuclei. Brain Res 2007. 1149:118-126.
-
(2007)
Brain Res
, vol.1149
, pp. 118-126
-
-
Vrang, N.1
Hansen, M.2
Larsen, P.J.3
Tang-Christensen, M.4
-
26
-
-
0031924498
-
Glucagonlike peptide 1(7-36) amide's central inhibition of feeding and peripheral inhibition of drinking are abolished by neonatal monosodium glutamate treatment
-
Tang-Christensen M, Vrang N, Larsen PJ. Glucagonlike peptide 1(7-36) amide's central inhibition of feeding and peripheral inhibition of drinking are abolished by neonatal monosodium glutamate treatment. Diabetes 1998. 47:530-537.
-
(1998)
Diabetes
, vol.47
, pp. 530-537
-
-
Tang-Christensen, M.1
Vrang, N.2
Larsen, P.J.3
-
28
-
-
0032830989
-
Interoceptive stress activates glucagon-like peptide-1 neurons that project to the hypothalamus
-
Rinaman L. Interoceptive stress activates glucagon-like peptide-1 neurons that project to the hypothalamus. Am J Physiol 1999. 277:R582-R590.
-
(1999)
Am J Physiol
, vol.277
-
-
Rinaman, L.1
-
29
-
-
0029903111
-
Glucagonlike peptide I receptors in the subfornical organ and the area postrema are accessible to circulating glucagon-like peptide I
-
Orskov C, Poulsen SS, Møller M, Holst JJ. Glucagonlike peptide I receptors in the subfornical organ and the area postrema are accessible to circulating glucagon-like peptide I. Diabetes 1996. 45:832-835.
-
(1996)
Diabetes
, vol.45
, pp. 832-835
-
-
Orskov, C.1
Poulsen, S.S.2
Møller, M.3
Holst, J.J.4
-
30
-
-
67649636449
-
Intrameal hepatic portal and intraperitoneal infusions of glucagon-like peptide-1 reduce spontaneous meal size in the rat via different mechanisms
-
Rüttimann EB, Arnold M, Hillebrand JJ, Geary N, Langhans W. Intrameal hepatic portal and intraperitoneal infusions of glucagon-like peptide-1 reduce spontaneous meal size in the rat via different mechanisms. Endocrinology 2009. 150:1174-1181.
-
(2009)
Endocrinology
, vol.150
, pp. 1174-1181
-
-
Rüttimann, E.B.1
Arnold, M.2
Hillebrand, J.J.3
Geary, N.4
Langhans, W.5
-
31
-
-
41349098117
-
An albumin-exendin-4 conjugate engages central and peripheral circuits regulating murine energy and glucose homeostasis
-
Baggio LL, Huang Q, Cao X, Drucker DJ. An albumin-exendin-4 conjugate engages central and peripheral circuits regulating murine energy and glucose homeostasis. Gastroenterology 2008. 134:1137-1147.
-
(2008)
Gastroenterology
, vol.134
, pp. 1137-1147
-
-
Baggio, L.L.1
Huang, Q.2
Cao, X.3
Drucker, D.J.4
-
32
-
-
70349664297
-
Potential of albiglutide, a long-acting GLP-1 receptor agonist, in type 2 diabetes: A randomized controlled trial exploring weekly, biweekly, and monthly dosing
-
Rosenstock J, Reusch J, Bush M, Yang F, Stewart M. Potential of albiglutide, a long-acting GLP-1 receptor agonist, in type 2 diabetes: a randomized controlled trial exploring weekly, biweekly, and monthly dosing. Diabetes Care 2009. 32:1880-1886.
-
(2009)
Diabetes Care
, vol.32
, pp. 1880-1886
-
-
Rosenstock, J.1
Reusch, J.2
Bush, M.3
Yang, F.4
Stewart, M.5
-
33
-
-
0037195478
-
Glucagon-like peptide-1 evokes action potentials and increases cytosolic Ca2+ in rat nodose ganglion neurons
-
Kakei M, Yada T, Nakagawa A, Nakabayashi H. Glucagon-like peptide-1 evokes action potentials and increases cytosolic Ca2+ in rat nodose ganglion neurons. Auton Neurosci 2002. 102:39-44.
-
(2002)
Auton Neurosci
, vol.102
, pp. 39-44
-
-
Kakei, M.1
Yada, T.2
Nakagawa, A.3
Nakabayashi, H.4
-
34
-
-
35748957503
-
The physiology of glucagon-like peptide 1
-
Holst JJ. The physiology of glucagon-like peptide 1. Physiol Rev 2007. 87:1409-1439.
-
(2007)
Physiol Rev
, vol.87
, pp. 1409-1439
-
-
Holst, J.J.1
-
35
-
-
0024210769
-
Gastric distension and gastric capacity in relation to food intake in humans
-
Geliebter A. Gastric distension and gastric capacity in relation to food intake in humans. Physiol Behav 1988. 44:665-668.
-
(1988)
Physiol Behav
, vol.44
, pp. 665-668
-
-
Geliebter, A.1
-
36
-
-
0030667056
-
Glucagon-like peptide 1 inhibition of gastric emptying outweighs its insulinotropic effects in healthy humans
-
Nauck MA, Niedereichholz U, Ettler R, Holst JJ, Orskov C, Ritzel R, Schmiegel WH. Glucagon-like peptide 1 inhibition of gastric emptying outweighs its insulinotropic effects in healthy humans. Am J Physiol 1997. 273:E981-E988.
-
(1997)
Am J Physiol
, vol.273
-
-
Nauck, M.A.1
Niedereichholz, U.2
Ettler, R.3
Holst, J.J.4
Orskov, C.5
Ritzel, R.6
Schmiegel, W.H.7
-
37
-
-
77649085155
-
Gastrointestinal targets of appetite regulation in humans
-
Delzenne N, Blundell J, Brouns F, Cunningham K, De Graaf K, Erkner A, Lluch A, Mars M, Peters HPF, Westerterp-Plantenga M. Gastrointestinal targets of appetite regulation in humans. Obes Rev 2010. 11:234-250.
-
(2010)
Obes Rev
, vol.11
, pp. 234-250
-
-
Delzenne, N.1
Blundell, J.2
Brouns, F.3
Cunningham, K.4
de Graaf, K.5
Erkner, A.6
Lluch, A.7
Mars, M.8
Peters, H.P.F.9
Westerterp-Plantenga, M.10
-
38
-
-
0002300343
-
Glucagon-like peptide-1: A potent regulator of food intake in humans
-
Gutzwiller JP, Göke B, Drewe J, Hildebrand P, Ketterer S, Handschin D, Winterhalder R, Conen D, Beglinger C. Glucagon-like peptide-1: a potent regulator of food intake in humans. Gut 1999. 44:81-86.
-
(1999)
Gut
, vol.44
, pp. 81-86
-
-
Gutzwiller, J.P.1
Göke, B.2
Drewe, J.3
Hildebrand, P.4
Ketterer, S.5
Handschin, D.6
Winterhalder, R.7
Conen, D.8
Beglinger, C.9
-
39
-
-
79960616174
-
Liraglutide: Short-lived effect on gastric emptying - long-lasting effects on body-weight
-
Knudsen LB, Tang-Christensen M, Jelsing J, Vrang N, Raun K. Liraglutide: short-lived effect on gastric emptying - long-lasting effects on body-weight. Diabetologia 2010. 53:860.
-
(2010)
Diabetologia
, vol.53
, pp. 860
-
-
Knudsen, L.B.1
Tang-Christensen, M.2
Jelsing, J.3
Vrang, N.4
Raun, K.5
-
40
-
-
79959404178
-
Rapid tachyphylaxis of the glucagon-like peptide 1-induced deceleration of gastric emptying in humans
-
Nauck MA, Kemmeries G, Holst JJ, Meier JJ. Rapid tachyphylaxis of the glucagon-like peptide 1-induced deceleration of gastric emptying in humans. Diabetes 2011. 60:1561-1565.
-
(2011)
Diabetes
, vol.60
, pp. 1561-1565
-
-
Nauck, M.A.1
Kemmeries, G.2
Holst, J.J.3
Meier, J.J.4
-
41
-
-
0027184119
-
Exendin-4 is a high potency agonist and truncated exendin-(9-39)-amide an antagonist at the glucagon-like peptide 1-(7-36)-amide receptor of insulinsecreting beta-cells
-
Göke R, Fehmann HC, Linn T, Schmidt H, Krause M, Eng J, Göke B. Exendin-4 is a high potency agonist and truncated exendin-(9-39)-amide an antagonist at the glucagon-like peptide 1-(7-36)-amide receptor of insulinsecreting beta-cells. J Biol Chem 1993. 268:19650-19655.
-
(1993)
J Biol Chem
, vol.268
, pp. 19650-19655
-
-
Göke, R.1
Fehmann, H.C.2
Linn, T.3
Schmidt, H.4
Krause, M.5
Eng, J.6
Göke, B.7
-
42
-
-
0026648961
-
Isolation and characterization of exendin-4, an exendin-3 analogue, from Heloderma suspectum venom. Further evidence for an exendin receptor on dispersed acini from guinea pig pancreas
-
Eng J, Kleinman WA, Singh L, Singh G, Raufman JP. Isolation and characterization of exendin-4, an exendin-3 analogue, from Heloderma suspectum venom. Further evidence for an exendin receptor on dispersed acini from guinea pig pancreas. J Biol Chem 1992. 267:7402-7405.
-
(1992)
J Biol Chem
, vol.267
, pp. 7402-7405
-
-
Eng, J.1
Kleinman, W.A.2
Singh, L.3
Singh, G.4
Raufman, J.P.5
-
43
-
-
77956893157
-
Liraglutide: The therapeutic promise from animal models
-
Knudsen LB. Liraglutide: the therapeutic promise from animal models. Int J Clin Pract Suppl 2010. 64:4-11.
-
(2010)
Int J Clin Pract Suppl
, vol.64
, pp. 4-11
-
-
Knudsen, L.B.1
-
44
-
-
84855657088
-
Safety, tolerability and sustained weight loss over 2 years with the once-daily human GLP-1 analog, liraglutide
-
In press
-
Astrup A, Carraro R, Finer N, Harper A, Kunesova M, Lean ME, Niskanen L, Rasmussen MF, Rissanen A, Rössner S, et al. Safety, tolerability and sustained weight loss over 2 years with the once-daily human GLP-1 analog, liraglutide. Int J Obes (Lond) 2011. In press.
-
(2011)
Int J Obes (Lond)
-
-
Astrup, A.1
Carraro, R.2
Finer, N.3
Harper, A.4
Kunesova, M.5
Lean, M.E.6
Niskanen, L.7
Rasmussen, M.F.8
Rissanen, A.9
Rössner, S.10
-
45
-
-
77951523535
-
Association of pancreatitis with glucagon-like peptide-1 agonist use
-
Anderson SL, Trujillo JM. Association of pancreatitis with glucagon-like peptide-1 agonist use. Ann Pharmacother 2010. 44:904-909.
-
(2010)
Ann Pharmacother
, vol.44
, pp. 904-909
-
-
Anderson, S.L.1
Trujillo, J.M.2
-
46
-
-
65949111736
-
Increased risk of acute pancreatitis and biliary disease observed in patients with type 2 diabetes: A retrospective cohort study
-
Noel RA, Braun DK, Patterson RE, Bloomgren GL. Increased risk of acute pancreatitis and biliary disease observed in patients with type 2 diabetes: a retrospective cohort study. Diabetes Care 2009. 32:834-838.
-
(2009)
Diabetes Care
, vol.32
, pp. 834-838
-
-
Noel, R.A.1
Braun, D.K.2
Patterson, R.E.3
Bloomgren, G.L.4
-
47
-
-
84855983163
-
-
FDA briefing materials. Table of contents liraglutide. April 2, 2011
-
FDA briefing materials. Table of contents liraglutide. April 2, 2009. www.fda.gov/./Drugs/EndocrinologicandMetabolicDrugsAdvisoryCommittee/UCM148645.pdf, 2011.
-
(2009)
-
-
-
48
-
-
83655191987
-
Incretin receptors in non-neoplastic and neoplastic thyroid C cells in rodents and humans: Relevance for incretin-based diabetes therapy
-
In press
-
Waser B, Beetschen K, Pellegata NS, Reubi JC. Incretin receptors in non-neoplastic and neoplastic thyroid C cells in rodents and humans: relevance for incretin-based diabetes therapy. Neuroendocrinology 2011. In press.
-
(2011)
Neuroendocrinology
-
-
Waser, B.1
Beetschen, K.2
Pellegata, N.S.3
Reubi, J.C.4
-
49
-
-
77950228684
-
Glucagon-like Peptide-1 receptor agonists activate rodent thyroid C-cells causing calcitonin release and C-cell proliferation
-
Bjerre Knudsen L, Madsen LW, Andersen S, Almholt K, de Boer AS, Drucker DJ, Gotfredsen C, Egerod FL, Hegelund AC, Jacobsen H, et al. Glucagon-like Peptide-1 receptor agonists activate rodent thyroid C-cells causing calcitonin release and C-cell proliferation. Endocrinology 2010. 151:1473-1486.
-
(2010)
Endocrinology
, vol.151
, pp. 1473-1486
-
-
Bjerre, K.L.1
Madsen, L.W.2
Andersen, S.3
Almholt, K.4
de Boer, A.S.5
Drucker, D.J.6
Gotfredsen, C.7
Egerod, F.L.8
Hegelund, A.C.9
Jacobsen, H.10
-
50
-
-
79959559653
-
Pancreatitis, pancreatic, and thyroid cancer with glucagon-like peptide-1-based therapies
-
Elashoff M, Matveyenko AV, Gier B, Elashoff R, Butler PC. Pancreatitis, pancreatic, and thyroid cancer with glucagon-like peptide-1-based therapies. Gastroenterology 2011. 141:150-156.
-
(2011)
Gastroenterology
, vol.141
, pp. 150-156
-
-
Elashoff, M.1
Matveyenko, A.V.2
Gier, B.3
Elashoff, R.4
Butler, P.C.5
-
51
-
-
84856000245
-
-
Anti-diabetic drugs: cardio/cerebrovascular adverse effect and pancreatitis/pancreatic cancer. European Medicines Agency, Priorities for Drug Safety Research
-
Anti-diabetic drugs: cardio/cerebrovascular adverse effect and pancreatitis/pancreatic cancer. European Medicines Agency, 2011, Priorities for Drug Safety Research.
-
(2011)
-
-
-
52
-
-
0031690479
-
Inhibition of the activity of dipeptidyl-peptidase IV as a treatment for type 2 diabetes
-
Holst JJ, Deacon CF. Inhibition of the activity of dipeptidyl-peptidase IV as a treatment for type 2 diabetes. Diabetes 1998. 47:1663-1670.
-
(1998)
Diabetes
, vol.47
, pp. 1663-1670
-
-
Holst, J.J.1
Deacon, C.F.2
-
53
-
-
33644842108
-
Dipeptidyl peptidase IV inhibitors: A promising new therapeutic approach for the management of type 2 diabetes
-
Deacon CF, Holst JJ. Dipeptidyl peptidase IV inhibitors: a promising new therapeutic approach for the management of type 2 diabetes. Int J Biochem Cell Biol 2006. 38:831-844.
-
(2006)
Int J Biochem Cell Biol
, vol.38
, pp. 831-844
-
-
Deacon, C.F.1
Holst, J.J.2
-
54
-
-
9444285818
-
Twelve- and 52-week efficacy of the dipeptidyl peptidase IV inhibitor LAF237 in metformin-treated patients with type 2 diabetes
-
Ahren B, Gomis R, Standl E, Mills D, Schweizer A. Twelve- and 52-week efficacy of the dipeptidyl peptidase IV inhibitor LAF237 in metformin-treated patients with type 2 diabetes. Diabetes Care 2004. 27:2874-2880.
-
(2004)
Diabetes Care
, vol.27
, pp. 2874-2880
-
-
Ahren, B.1
Gomis, R.2
Standl, E.3
Mills, D.4
Schweizer, A.5
-
55
-
-
41549105255
-
Glucagon-like peptide-1, glucose homeostasis and diabetes
-
Holst JJ, Deacon CF, Vilsboll T, Krarup T, Madsbad S. Glucagon-like peptide-1, glucose homeostasis and diabetes. Trends Mol Med 2008. 14:161-168.
-
(2008)
Trends Mol Med
, vol.14
, pp. 161-168
-
-
Holst, J.J.1
Deacon, C.F.2
Vilsboll, T.3
Krarup, T.4
Madsbad, S.5
-
56
-
-
0027220436
-
Glucagonlike peptide-1-(7-36) amide, oxyntomodulin, and glucagon interact with a common receptor in a somatostatin-secreting cell line
-
Gros L, Thorens B, Bataille D, Kervran A. Glucagonlike peptide-1-(7-36) amide, oxyntomodulin, and glucagon interact with a common receptor in a somatostatin-secreting cell line. Endocrinology 1993. 133:631-638
-
(1993)
Endocrinology
, vol.133
, pp. 631-638
-
-
Gros, L.1
Thorens, B.2
Bataille, D.3
Kervran, A.4
-
57
-
-
0023910424
-
Oxyntomodulin (glicentin-(33-69)): Pharmacokinetics, binding to liver cell membranes, effects on isolated perfused pig pancreas, and secretion from isolated perfused lower small intestine of pigs
-
Baldissera FG, Holst JJ, Knuhtsen S, Hilsted L, Nielsen OV. Oxyntomodulin (glicentin-(33-69)): pharmacokinetics, binding to liver cell membranes, effects on isolated perfused pig pancreas, and secretion from isolated perfused lower small intestine of pigs. Regul Pept 1988. 21:151-166.
-
(1988)
Regul Pept
, vol.21
, pp. 151-166
-
-
Baldissera, F.G.1
Holst, J.J.2
Knuhtsen, S.3
Hilsted, L.4
Nielsen, O.V.5
-
58
-
-
0030901415
-
Enteroglucagon
-
Holst JJ. Enteroglucagon. Annu Rev Physiol 1997. 59:257-271.
-
(1997)
Annu Rev Physiol
, vol.59
, pp. 257-271
-
-
Holst, J.J.1
-
59
-
-
0020377971
-
Isolation of glucagon-37 (bioactive enteroglucagon/oxyntomodulin) from porcine jejuno-ileum. Characterization of the peptide
-
Bataille D, Tatemoto K, Gespach C, Jörnvall H, Rosselin G, Mutt V. Isolation of glucagon-37 (bioactive enteroglucagon/oxyntomodulin) from porcine jejuno-ileum. Characterization of the peptide. FEBS Lett 1982. 146:79-86.
-
(1982)
FEBS Lett
, vol.146
, pp. 79-86
-
-
Bataille, D.1
Tatemoto, K.2
Gespach, C.3
Jörnvall, H.4
Rosselin, G.5
Mutt, V.6
-
60
-
-
0023714388
-
Oxyntomodulin: A potential hormone from the distal gut. Pharmacokinetics and effects on gastric acid and insulin secretion in man
-
Schjoldager BT, Baldissera FG, Mortensen PE, Holst JJ, Christiansen J. Oxyntomodulin: a potential hormone from the distal gut. Pharmacokinetics and effects on gastric acid and insulin secretion in man. Eur J Clin Invest 1988. 18:499-503.
-
(1988)
Eur J Clin Invest
, vol.18
, pp. 499-503
-
-
Schjoldager, B.T.1
Baldissera, F.G.2
Mortensen, P.E.3
Holst, J.J.4
Christiansen, J.5
-
61
-
-
63849300305
-
Investigation of structure-activity relationships of Oxyntomodulin (Oxm) using Oxm analogs
-
Druce MR, Minnion JS, Field BC, Patel SR, Shillito JC, Tilby M, Beale KE, Murphy KG, Ghatei MA, Bloom SR. Investigation of structure-activity relationships of Oxyntomodulin (Oxm) using Oxm analogs. Endocrinology 2009. 150:1712-1722.
-
(2009)
Endocrinology
, vol.150
, pp. 1712-1722
-
-
Druce, M.R.1
Minnion, J.S.2
Field, B.C.3
Patel, S.R.4
Shillito, J.C.5
Tilby, M.6
Beale, K.E.7
Murphy, K.G.8
Ghatei, M.A.9
Bloom, S.R.10
-
62
-
-
0034807498
-
Oxyntomodulin inhibits food intake in the rat
-
Dakin CL, Gunn I, Small CJ, Edwards CM, Hay DL, Smith DM, Ghatei MA, Bloom SR. Oxyntomodulin inhibits food intake in the rat. Endocrinology 2001. 142:4244-4250.
-
(2001)
Endocrinology
, vol.142
, pp. 4244-4250
-
-
Dakin, C.L.1
Gunn, I.2
Small, C.J.3
Edwards, C.M.4
Hay, D.L.5
Smith, D.M.6
Ghatei, M.A.7
Bloom, S.R.8
-
63
-
-
23644443678
-
Subcutaneous oxyntomodulin reduces body weight in overweight and obese subjects: A double-blind, randomized, controlled trial
-
Wynne K, Park AJ, Small CJ, Patterson M, Ellis SM, Murphy KG, Wren AM, Frost GS, Meeran K, Ghatei MA, et al. Subcutaneous oxyntomodulin reduces body weight in overweight and obese subjects: a double-blind, randomized, controlled trial. Diabetes 2005. 54:2390-2395.
-
(2005)
Diabetes
, vol.54
, pp. 2390-2395
-
-
Wynne, K.1
Park, A.J.2
Small, C.J.3
Patterson, M.4
Ellis, S.M.5
Murphy, K.G.6
Wren, A.M.7
Frost, G.S.8
Meeran, K.9
Ghatei, M.A.10
-
64
-
-
33749339257
-
Oxyntomodulin increases energy expenditure in addition to decreasing energy intake in overweight and obese humans: A randomised controlled trial
-
Wynne K, Park AJ, Small CJ, Meeran K, Ghatei MA, Frost GS, Bloom SR. Oxyntomodulin increases energy expenditure in addition to decreasing energy intake in overweight and obese humans: a randomised controlled trial. Int J Obes (Lond) 2006. 30:1729-1736.
-
(2006)
Int J Obes (Lond)
, vol.30
, pp. 1729-1736
-
-
Wynne, K.1
Park, A.J.2
Small, C.J.3
Meeran, K.4
Ghatei, M.A.5
Frost, G.S.6
Bloom, S.R.7
-
65
-
-
70349644658
-
Glucagon-like peptide 1/glucagon receptor dual agonism reverses obesity in mice
-
Pocai A, Carrington PE, Adams JR, Wright M, Eiermann G, Zhu L, Du X, Petrov A, Lassman ME, Jiang G, et al. Glucagon-like peptide 1/glucagon receptor dual agonism reverses obesity in mice. Diabetes 2009. 58:2258-2266.
-
(2009)
Diabetes
, vol.58
, pp. 2258-2266
-
-
Pocai, A.1
Carrington, P.E.2
Adams, J.R.3
Wright, M.4
Eiermann, G.5
Zhu, L.6
Du, X.7
Petrov, A.8
Lassman, M.E.9
Jiang, G.10
-
66
-
-
4143116741
-
Oxyntomodulin and glucagon-like peptide-1 differentially regulate murine food intake and energy expenditure
-
Baggio LL, Huang Q, Brown TJ, Drucker DJ. Oxyntomodulin and glucagon-like peptide-1 differentially regulate murine food intake and energy expenditure. Gastroenterology 2004. 127:546-558.
-
(2004)
Gastroenterology
, vol.127
, pp. 546-558
-
-
Baggio, L.L.1
Huang, Q.2
Brown, T.J.3
Drucker, D.J.4
-
67
-
-
0022398837
-
Human distribution and release of a putative new gut hormone, peptide YY
-
Adrian TE, Ferri GL, Bacarese-Hamilton AJ, Fuessl HS, Polak JM, Bloom SR. Human distribution and release of a putative new gut hormone, peptide YY. Gastroenterology 1985. 89:1070-1077.
-
(1985)
Gastroenterology
, vol.89
, pp. 1070-1077
-
-
Adrian, T.E.1
Ferri, G.L.2
Bacarese-Hamilton, A.J.3
Fuessl, H.S.4
Polak, J.M.5
Bloom, S.R.6
-
68
-
-
0029826237
-
Influence of meal composition on postprandial peripheral plasma concentrations of vasoactive peptides in man
-
Pedersen-Bjergaard U, Host U, Kelbaek H, Schifter S, Rehfeld JF, Faber J, Christensen NJ. Influence of meal composition on postprandial peripheral plasma concentrations of vasoactive peptides in man. Scand J Clin Lab Invest 1996. 56:497-503.
-
(1996)
Scand J Clin Lab Invest
, vol.56
, pp. 497-503
-
-
Pedersen-Bjergaard, U.1
Host, U.2
Kelbaek, H.3
Schifter, S.4
Rehfeld, J.F.5
Faber, J.6
Christensen, N.J.7
-
69
-
-
0019310264
-
Isolation of two novel candidate hormones using a chemical method for finding naturally occurring polypeptides
-
Tatemoto K, Mutt V. Isolation of two novel candidate hormones using a chemical method for finding naturally occurring polypeptides. Nature 1980. 285:417-418.
-
(1980)
Nature
, vol.285
, pp. 417-418
-
-
Tatemoto, K.1
Mutt, V.2
-
70
-
-
0027494070
-
Proteolytic processing of neuropeptide Y and peptide YY by dipeptidyl peptidase IV
-
Mentlein R, Dahms P, Grandt D, Krüger R. Proteolytic processing of neuropeptide Y and peptide YY by dipeptidyl peptidase IV. Regul Pept 1993. 49:133-144.
-
(1993)
Regul Pept
, vol.49
, pp. 133-144
-
-
Mentlein, R.1
Dahms, P.2
Grandt, D.3
Krüger, R.4
-
71
-
-
0028173653
-
Two molecular forms of peptide YY (PYY) are abundant in human blood: Characterization of a radioimmunoassay recognizing PYY 1-36 and PYY 3-36
-
Grandt D, Schimiczek M, Beglinger C, Layer P, Goebell H, Eysselein VE, Reeve JR Jr. Two molecular forms of peptide YY (PYY) are abundant in human blood: characterization of a radioimmunoassay recognizing PYY 1-36 and PYY 3-36. Regul Pept 1994. 51:151-159.
-
(1994)
Regul Pept
, vol.51
, pp. 151-159
-
-
Grandt, D.1
Schimiczek, M.2
Beglinger, C.3
Layer, P.4
Goebell, H.5
Eysselein, V.E.6
Reeve Jr., J.R.7
-
73
-
-
0023137272
-
Effects of peptide YY (PYY) on mouth to caecum intestinal transit time and on the rate of gastric emptying in healthy volunteers
-
Savage AP, Adrian TE, Carolan G, Chatterjee VK, Bloom SR. Effects of peptide YY (PYY) on mouth to caecum intestinal transit time and on the rate of gastric emptying in healthy volunteers. Gut 1987. 28:166-170.
-
(1987)
Gut
, vol.28
, pp. 166-170
-
-
Savage, A.P.1
Adrian, T.E.2
Carolan, G.3
Chatterjee, V.K.4
Bloom, S.R.5
-
74
-
-
0021997192
-
Effect of peptide YY on gastric, pancreatic, and biliary function in humans
-
Adrian TE, Savage AP, Sagor GR, Allen JM, Bacarese-Hamilton AJ, Tatemoto K, Polak JM, Bloom SR. Effect of peptide YY on gastric, pancreatic, and biliary function in humans. Gastroenterology 1985. 89:494-499.
-
(1985)
Gastroenterology
, vol.89
, pp. 494-499
-
-
Adrian, T.E.1
Savage, A.P.2
Sagor, G.R.3
Allen, J.M.4
Bacarese-Hamilton, A.J.5
Tatemoto, K.6
Polak, J.M.7
Bloom, S.R.8
-
75
-
-
0036013030
-
Receptor subtypes Y1 and Y5 mediate neuropeptide Y induced feeding in the guinea-pig
-
Lecklin A, Lundell I, Paananen L, Wikberg JE, Männistö PT, Larhammar D. Receptor subtypes Y1 and Y5 mediate neuropeptide Y induced feeding in the guinea-pig. Br J Pharmacol 2002. 135:2029-2037.
-
(2002)
Br J Pharmacol
, vol.135
, pp. 2029-2037
-
-
Lecklin, A.1
Lundell, I.2
Paananen, L.3
Wikberg, J.E.4
Männistö, P.T.5
Larhammar, D.6
-
76
-
-
77954380946
-
Twelve weeks treatment with the DPP-4 inhibitor, sitagliptin, prevents degradation of peptide YY and improves glucose and non-glucose induced insulin secretion in patients with type 2 diabetes mellitus
-
Aaboe K, Knop FK, Vilsboll T, Deacon CF, Holst JJ, Madsbad S, Krarup T. Twelve weeks treatment with the DPP-4 inhibitor, sitagliptin, prevents degradation of peptide YY and improves glucose and non-glucose induced insulin secretion in patients with type 2 diabetes mellitus. Diabetes Obes Metab 2010. 12:323-333.
-
(2010)
Diabetes Obes Metab
, vol.12
, pp. 323-333
-
-
Aaboe, K.1
Knop, F.K.2
Vilsboll, T.3
Deacon, C.F.4
Holst, J.J.5
Madsbad, S.6
Krarup, T.7
-
77
-
-
34047216695
-
Effects of PYY1-36 and PYY3-36 on appetite, energy intake, energy expenditure, glucose and fat metabolism in obese and lean subjects
-
Sloth B, Holst JJ, Flint A, Gregersen NT, Astrup A. Effects of PYY1-36 and PYY3-36 on appetite, energy intake, energy expenditure, glucose and fat metabolism in obese and lean subjects. Am J Physiol Endocrinol Metab 2007. 292:E1062-E1068.
-
(2007)
Am J Physiol Endocrinol Metab
, vol.292
-
-
Sloth, B.1
Holst, J.J.2
Flint, A.3
Gregersen, N.T.4
Astrup, A.5
-
78
-
-
34249862701
-
Efficacy and safety of intranasal peptide YY3-36 for weight reduction in obese adults
-
Gantz I, Erondu N, Mallick M, Musser B, Krishna R, Tanaka WK, Snyder K, Stevens C, Stroh MA, Zhu H, et al. Efficacy and safety of intranasal peptide YY3-36 for weight reduction in obese adults. J Clin Endocrinol Metab 2007. 92:1754-1757.
-
(2007)
J Clin Endocrinol Metab
, vol.92
, pp. 1754-1757
-
-
Gantz, I.1
Erondu, N.2
Mallick, M.3
Musser, B.4
Krishna, R.5
Tanaka, W.K.6
Snyder, K.7
Stevens, C.8
Stroh, M.A.9
Zhu, H.10
-
79
-
-
77954252801
-
PYY3-36 and oxyntomodulin can be additive in their effect on food intake in overweight and obese humans
-
Field BC, Wren AM, Peters V, Baynes KC, Martin NM, Patterson M, Alsaraf S, Amber V, Wynne K, Ghatei MA, et al. PYY3-36 and oxyntomodulin can be additive in their effect on food intake in overweight and obese humans. Diabetes 2010. 59:1635-1639.
-
(2010)
Diabetes
, vol.59
, pp. 1635-1639
-
-
Field, B.C.1
Wren, A.M.2
Peters, V.3
Baynes, K.C.4
Martin, N.M.5
Patterson, M.6
Alsaraf, S.7
Amber, V.8
Wynne, K.9
Ghatei, M.A.10
-
80
-
-
0017899221
-
Immunochemical studies on cholecystokinin. II. Distribution and molecular heterogeneity in the central nervous system and small intestine of man and hog
-
Rehfeld JF. Immunochemical studies on cholecystokinin. II. Distribution and molecular heterogeneity in the central nervous system and small intestine of man and hog. J Biol Chem 1978. 253:4022-4030.
-
(1978)
J Biol Chem
, vol.253
, pp. 4022-4030
-
-
Rehfeld, J.F.1
-
81
-
-
33745605514
-
The endoproteolytic maturation of progastrin and procholecystokinin
-
Rehfeld JF. The endoproteolytic maturation of progastrin and procholecystokinin. J Mol Med 2006. 84:544-550.
-
(2006)
J Mol Med
, vol.84
, pp. 544-550
-
-
Rehfeld, J.F.1
-
82
-
-
0025815331
-
Bischof-Delaloye A. Role of cholecystokinin in the regulation of gastric emptying and pancreatic enzyme secretion in humans. Studies with the cholecystokinin-receptor antagonist loxiglumide
-
Fried M, Erlacher U, Schwizer W, Löchner C, Koerfer J, Beglinger C, Jansen JB, Lamers CB, Harder F, Bischof-Delaloye A. Role of cholecystokinin in the regulation of gastric emptying and pancreatic enzyme secretion in humans. Studies with the cholecystokinin-receptor antagonist loxiglumide. Gastroenterology 1991. 101:503-511.
-
(1991)
Gastroenterology
, vol.101
, pp. 503-511
-
-
Fried, M.1
Erlacher, U.2
Schwizer, W.3
Löchner, C.4
Koerfer, J.5
Beglinger, C.6
Jansen, J.B.7
Lamers, C.B.8
Harder, F.9
-
83
-
-
0026040149
-
Cholinergic dependence of gallbladder response to cholecystokinin in the guinea pig in vivo
-
Takahashi T, May D, Owyang C. Cholinergic dependence of gallbladder response to cholecystokinin in the guinea pig in vivo. Am J Physiol 1991. 261:G565-G569.
-
(1991)
Am J Physiol
, vol.261
-
-
Takahashi, T.1
May, D.2
Owyang, C.3
-
84
-
-
76149116843
-
Role of fat hydrolysis in regulating glucagon-like Peptide-1 secretion
-
Beglinger S, Drewe J, Schirra J, Göke B, D'Amato M, Beglinger C. Role of fat hydrolysis in regulating glucagon-like Peptide-1 secretion. J Clin Endocrinol Metab 2010. 95:879-886.
-
(2010)
J Clin Endocrinol Metab
, vol.95
, pp. 879-886
-
-
Beglinger, S.1
Drewe, J.2
Schirra, J.3
Göke, B.4
D'amato, M.5
Beglinger, C.6
-
85
-
-
34147178061
-
Effect of CCK-1 receptor blockade on ghrelin and PYY secretion in men
-
Degen L, Drewe J, Piccoli F, Gräni K, Oesch S, Bunea R, D'Amato M, Beglinger C. Effect of CCK-1 receptor blockade on ghrelin and PYY secretion in men. Am J Physiol Regul Integr Comp Physiol 2007. 292:R1391-R1399.
-
(2007)
Am J Physiol Regul Integr Comp Physiol
, vol.292
-
-
Degen, L.1
Drewe, J.2
Piccoli, F.3
Gräni, K.4
Oesch, S.5
Bunea, R.6
D'amato, M.7
Beglinger, C.8
-
86
-
-
0017855781
-
Localisation of gastrins to neuro- and adenohypophysis
-
Rehfeld JF. Localisation of gastrins to neuro- and adenohypophysis. Nature 1978. 271:771-773.
-
(1978)
Nature
, vol.271
, pp. 771-773
-
-
Rehfeld, J.F.1
-
87
-
-
0023010844
-
Intracranial infusion of CCK-8 derivatives suppresses food intake in rats
-
Mori T, Nagai K, Nakagawa H, Yanaihara N. Intracranial infusion of CCK-8 derivatives suppresses food intake in rats. Am J Physiol 1986. 251:R718-R723.
-
(1986)
Am J Physiol
, vol.251
-
-
Mori, T.1
Nagai, K.2
Nakagawa, H.3
Yanaihara, N.4
-
88
-
-
0021433344
-
Cholecystokinin persistently suppresses meal size but not food intake in freefeeding rats
-
West DB, Fey D, Woods SC. Cholecystokinin persistently suppresses meal size but not food intake in freefeeding rats. Am J Physiol 1984. 246:R776-R787.
-
(1984)
Am J Physiol
, vol.246
-
-
West, D.B.1
Fey, D.2
Woods, S.C.3
-
90
-
-
38349104637
-
Stimulation of cholecystokinin-A receptors with GI181771X does not cause weight loss in overweight or obese patients
-
Jordan J, Greenway FL, Leiter LA, Li Z, Jacobson P, Murphy K, Hill J, Kler L, Aftring RP. Stimulation of cholecystokinin-A receptors with GI181771X does not cause weight loss in overweight or obese patients. Clin Pharmacol Ther 2008. 83:281-287.
-
(2008)
Clin Pharmacol Ther
, vol.83
, pp. 281-287
-
-
Jordan, J.1
Greenway, F.L.2
Leiter, L.A.3
Li, Z.4
Jacobson, P.5
Murphy, K.6
Hill, J.7
Kler, L.8
Aftring, R.P.9
-
91
-
-
0033052247
-
Behavioral effects of AR-R 15849, a highly selective CCK-A agonist
-
Simmons RD, Kaiser FC, Hudzik TJ. Behavioral effects of AR-R 15849, a highly selective CCK-A agonist. Pharmacol Biochem Behav 1999. 62:549-557.
-
(1999)
Pharmacol Biochem Behav
, vol.62
, pp. 549-557
-
-
Simmons, R.D.1
Kaiser, F.C.2
Hudzik, T.J.3
-
92
-
-
0026691637
-
Behavioral effects of A71623, a highly selective CCKA agonist tetrapeptide
-
Asin KE, Bednarz L, Nikkel AL, Gore PA Jr, Montana WE, Cullen MJ, Shiosaki K, Craig R, Nadzan AM. Behavioral effects of A71623, a highly selective CCKA agonist tetrapeptide. Am J Physiol 1992. 263:R125-R135.
-
(1992)
Am J Physiol
, vol.263
-
-
Asin, K.E.1
Bednarz, L.2
Nikkel, A.L.3
Gore Jr., P.A.4
Montana, W.E.5
Cullen, M.J.6
Shiosaki, K.7
Craig, R.8
Nadzan, A.M.9
-
93
-
-
41549102091
-
Leptin-mediated hypothalamic pathway of cholecystokinin (CCK-8) to regulate body weight in free-feeding rats
-
Merino B, Cano V, Guzman R, Somoza B, Ruiz-Gayo M. Leptin-mediated hypothalamic pathway of cholecystokinin (CCK-8) to regulate body weight in free-feeding rats. Endocrinology 2008. 149:1994-2000.
-
(2008)
Endocrinology
, vol.149
, pp. 1994-2000
-
-
Merino, B.1
Cano, V.2
Guzman, R.3
Somoza, B.4
Ruiz-Gayo, M.5
-
94
-
-
78951494193
-
Additive effects of cannabinoid CB1 receptors blockade and cholecystokinin on feeding inhibition
-
Orio L, Crespo I, Lopez-Moreno JA, Reyes-Cabello C, Rodriguez de Fonseca F, Gomez de Heras R. Additive effects of cannabinoid CB1 receptors blockade and cholecystokinin on feeding inhibition. Pharmacol Biochem Behav 2011. 98:220-226.
-
(2011)
Pharmacol Biochem Behav
, vol.98
, pp. 220-226
-
-
Orio, L.1
Crespo, I.2
Lopez-Moreno, J.A.3
Reyes-Cabello, C.4
de Fonseca, F.R.5
de Heras, R.G.6
-
95
-
-
38849090670
-
Identification of the acyltransferase that octanoylates ghrelin, an appetite-stimulating peptide hormone
-
Yang J, Brown MS, Liang G, Grishin NV, Goldstein JL. Identification of the acyltransferase that octanoylates ghrelin, an appetite-stimulating peptide hormone. Cell 2008. 132:387-396.
-
(2008)
Cell
, vol.132
, pp. 387-396
-
-
Yang, J.1
Brown, M.S.2
Liang, G.3
Grishin, N.V.4
Goldstein, J.L.5
-
96
-
-
2942528459
-
Biological, physiological, pathophysiological, and pharmacological aspects of ghrelin
-
van der Lely AJ, Tschöp M, Heiman ML, Ghigo E. Biological, physiological, pathophysiological, and pharmacological aspects of ghrelin. Endocr Rev 2004. 25:426-457.
-
(2004)
Endocr Rev
, vol.25
, pp. 426-457
-
-
van der Lely, A.J.1
Tschöp, M.2
Heiman, M.L.3
Ghigo, E.4
-
97
-
-
0033540056
-
Ghrelin is a growth-hormone-releasing acylated peptide from stomach
-
Kojima M, Hosoda H, Date Y, Nakazato M, Matsuo H, Kangawa K. Ghrelin is a growth-hormone-releasing acylated peptide from stomach. Nature 1999. 402:656-660.
-
(1999)
Nature
, vol.402
, pp. 656-660
-
-
Kojima, M.1
Hosoda, H.2
Date, Y.3
Nakazato, M.4
Matsuo, H.5
Kangawa, K.6
-
98
-
-
0035216623
-
Ghrelin enhances appetite and increases food intake in humans
-
Wren AM, Seal LJ, Cohen MA, Brynes AE, Frost GS, Murphy KG, Dhillo WS, Ghatei MA, Bloom SR. Ghrelin enhances appetite and increases food intake in humans. J Clin Endocrinol Metab 2001. 86:5992.
-
(2001)
J Clin Endocrinol Metab
, vol.86
, pp. 5992
-
-
Wren, A.M.1
Seal, L.J.2
Cohen, M.A.3
Brynes, A.E.4
Frost, G.S.5
Murphy, K.G.6
Dhillo, W.S.7
Ghatei, M.A.8
Bloom, S.R.9
-
99
-
-
0035433977
-
A preprandial rise in plasma ghrelin levels suggests a role in meal initiation in humans
-
Cummings DE, Purnell JQ, Frayo RS, Schmidova K, Wisse BE, Weigle DS. A preprandial rise in plasma ghrelin levels suggests a role in meal initiation in humans. Diabetes 2001. 50:1714-1719.
-
(2001)
Diabetes
, vol.50
, pp. 1714-1719
-
-
Cummings, D.E.1
Purnell, J.Q.2
Frayo, R.S.3
Schmidova, K.4
Wisse, B.E.5
Weigle, D.S.6
-
100
-
-
2942558193
-
Plasma ghrelin levels and hunger scores in humans initiating meals voluntarily without time- and foodrelated cues
-
Cummings DE, Frayo RS, Marmonier C, Aubert R, Chapelot D. Plasma ghrelin levels and hunger scores in humans initiating meals voluntarily without time- and foodrelated cues. Am J Physiol Endocrinol Metab 2004. 287:E297-E304.
-
(2004)
Am J Physiol Endocrinol Metab
, vol.287
-
-
Cummings, D.E.1
Frayo, R.S.2
Marmonier, C.3
Aubert, R.4
Chapelot, D.5
-
101
-
-
3142761626
-
Hyperghrelinemia is a common feature of Prader-Willi syndrome and pituitary stalk interruption: A pathophysiological hypothesis
-
Tauber M, Conte Auriol F, Moulin P, Molinas C, Delagnes V, Salles JP. Hyperghrelinemia is a common feature of Prader-Willi syndrome and pituitary stalk interruption: a pathophysiological hypothesis. Horm Res 2004. 62:49-54.
-
(2004)
Horm Res
, vol.62
, pp. 49-54
-
-
Tauber, M.1
Conte, A.F.2
Moulin, P.3
Molinas, C.4
Delagnes, V.5
Salles, J.P.6
-
102
-
-
85147051487
-
Food fails to suppress ghrelin levels in obese humans
-
English PJ, Ghatei MA, Malik IA, Bloom SR, Wilding JP. Food fails to suppress ghrelin levels in obese humans. J Clin Endocrinol Metab 2002. 87:2984.
-
J Clin Endocrinol Metab
, vol.2002
, pp. 87
-
-
English, P.J.1
Ghatei, M.A.2
Malik, I.A.3
Bloom, S.R.4
Wilding, J.P.5
-
103
-
-
1842480284
-
Ghrelin stimulation of growth hormone release and appetite is mediated through the growth hormone secretagogue receptor
-
Sun Y, Wang P, Zheng H, Smith RG. Ghrelin stimulation of growth hormone release and appetite is mediated through the growth hormone secretagogue receptor. Proc Natl Acad Sci USA 2004. 101:4679-4684.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 4679-4684
-
-
Sun, Y.1
Wang, P.2
Zheng, H.3
Smith, R.G.4
-
104
-
-
27344437877
-
A novel growth hormone secretagogue-1a receptor antagonist that blocks ghrelin-induced growth hormone secretion but induces increased body weight gain
-
Halem HA, Taylor JE, Dong JZ, Shen Y, Datta R, Abizaid A, Diano S, Horvath TL, Culler MD. A novel growth hormone secretagogue-1a receptor antagonist that blocks ghrelin-induced growth hormone secretion but induces increased body weight gain. Neuroendocrinology 2005. 81:339-349.
-
(2005)
Neuroendocrinology
, vol.81
, pp. 339-349
-
-
Halem, H.A.1
Taylor, J.E.2
Dong, J.Z.3
Shen, Y.4
Datta, R.5
Abizaid, A.6
Diano, S.7
Horvath, T.L.8
Culler, M.D.9
-
105
-
-
34247239893
-
Synthesis and pharmacological in vitro and in vivo evaluations of novel triazole derivatives as ligands of the ghrelin receptor
-
Demange L, Boeglin D, Moulin A, Mousseaux D, Ryan J, Berge G, Gagne D, Heitz A, Perrissoud D, Locatelli V, et al. Synthesis and pharmacological in vitro and in vivo evaluations of novel triazole derivatives as ligands of the ghrelin receptor. J Med Chem 2007. 50:1939-1957.
-
(2007)
J Med Chem
, vol.50
, pp. 1939-1957
-
-
Demange, L.1
Boeglin, D.2
Moulin, A.3
Mousseaux, D.4
Ryan, J.5
Berge, G.6
Gagne, D.7
Heitz, A.8
Perrissoud, D.9
Locatelli, V.10
|