Chronic methadone treatment shows a better cost/benefit ratio than chronic morphine in mice

Journal of Pharmacology and Experimental Therapeutics

Volumn 340, Issue 2, 2012, Pages 386-392

  Enquist, Johan ^a   Ferwerda, Madeline ^a   Milan Lobo, Laura ^a   Whistler, Jennifer L ^a,b  

^a UNIVERSITY OF CALIFORNIA SAN FRANCISCO   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

METHADONE; MORPHINE SULFATE; MU OPIATE RECEPTOR;

ANALGESIC ACTIVITY; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; COST BENEFIT ANALYSIS; DRUG CHOICE; DRUG DEPENDENCE; DRUG TOLERANCE; ENDOCYTOSIS; HEAT STRESS; LONG TERM CARE; MOUSE; MOUSE STRAIN; NONHUMAN; PAIN; PRIORITY JOURNAL; PROTECTION; PROTEIN DEGRADATION; RECEPTOR DOWN REGULATION; TAIL FLICK TEST; TREATMENT DURATION; WITHDRAWAL SYNDROME;

ANALGESICS, OPIOID; ANIMALS; AREA UNDER CURVE; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG TOLERANCE; ENDOCYTOSIS; GENE KNOCK-IN TECHNIQUES; METHADONE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MORPHINE; MUTATION; NALOXONE; PAIN; PAIN MEASUREMENT; PAIN THRESHOLD; RECEPTORS, OPIOID, MU; SUBSTANCE WITHDRAWAL SYNDROME; SUBSTANCE-RELATED DISORDERS;

EID: 84855999372     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.111.187583     Document Type: Article

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