Lack of Abcc3 expression impairs bile-acid induced liver growth and delays hepatic regeneration after partial hepatectomy in mice

Journal of Hepatology

Volumn 56, Issue 2, 2012, Pages 367-373

  Fernández Barrena, Maite G ^a,d   Monte, Maria J ^b,d   Latasa, Maria U ^a   Uriarte, Iker ^d   Vicente, Eva ^a   Chang, Haisul C Y ^a   Rodriguez Ortigosa, Carlos M ^a,d   Elferink, Ronald Oude ^c   Berasain, Carmen ^a   Marin, Jose J G ^b,d   Prieto, Jesus ^a,d   Ávila, Matias A ^a  

^a UNIVERSITY OF NAVARRA   (Spain)

^b UNIVERSITY OF SALAMANCA   (Spain)

^c ACADEMIC MEDICAL CENTER   (Netherlands)

^d INSTITUTO DE SALUD CARLOS III   (Spain)

Author keywords

Bile acids; Liver regeneration; Mrp3 Abcc3

Indexed keywords

ABCC3 PROTEIN; BILE ACID; CHOLIC ACID; FARNESOID X RECEPTOR; MULTIDRUG RESISTANCE PROTEIN 3; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; DIET SUPPLEMENTATION; DNA SYNTHESIS; GENE EXPRESSION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IN VIVO STUDY; LIVER; LIVER REGENERATION; MOUSE; NONHUMAN; PARTIAL HEPATECTOMY; PRIORITY JOURNAL; TANDEM MASS SPECTROMETRY;

ANIMALS; BILE ACIDS AND SALTS; BIOLOGICAL TRANSPORT, ACTIVE; CHOLIC ACID; HEPATECTOMY; LIVER; LIVER REGENERATION; MALE; MICE; MICE, KNOCKOUT; MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS; RECEPTORS, CYTOPLASMIC AND NUCLEAR; SIGNAL TRANSDUCTION;

EID: 84855979428     PISSN: 01688278     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jhep.2011.05.031     Document Type: Article

References (29)

1. G.K. Michalopoulos Liver regeneration J Cell Physiol 213 2007 286 300 (Pubitemid 47509705)
2. N. Fausto, J.S. Campbell, and K.J. Riehle Liver regeneration Hepatology 43 2006 S45 S53
3. W. Huang, K. Ma, J. Zhang, M. Qatanani, J. Cuvillier, and J. Liu Nuclear receptor-dependent bile acid signaling is required for normal liver regeneration Science 312 2006 233 236
4. I.L. Csanaky, L.M. Aleksunes, A.Y. Tanaka, and C.D. Klaassen Role of hepatic transporters in prevention of bile acid toxicity after partial hepatectomy in mice Am J Physiol Gastrointest Liver Physiol 297 2009 G419 G433
5. G.R. Sainz, M.J. Monte, E.R. Barbero, M.C. Herrera, and J.J.G. Marin Bile secretion by the rat liver during synchronized regeneration Int J Exp Pathol 78 1997 109 116 (Pubitemid 27241675)
6. A.F. Hofmann The enterohepatic circulation of bile acids in mammals: form and functions Front Biosci 14 2009 2584 2598
7. L. Zhang, X. Huang, Z. Meng, B. Dong, S. Shiah, and D.D. Moore Significance and mechanisms of CYP7a1 gene regulation during the acute phase of liver regeneration Mol Endocrinol 23 2009 137 145
8. Doignon I, Julien B, Serrire-Lanneau V, Garcin I, Alonso G, Nicou A, et al. Immediate neuroendocrine signaling after partial hepatectomy through acute portal hyperpressure and cholestasis. J Hepatol 2010, Epub ahead of print.
9. A. Rao, J. Haywood, A.L. Craddock, M.G. Belinsky, G.D. Kruh, and P.A. Dawson The organic solute transporter α-β, Ostα-Ostβ, is essential for intestinal bile acid transport and homeostasis Proc Natl Acad Sci USA 105 2008 3891 3896 (Pubitemid 351723495)
10. P. Borst, and C. de Wolf Van de Wetering. Multidrug resistance associated proteins 3, 4 and 5 Pflugers Arch-Eur J Physiol 453 2007 661 673
11. G. Zollner, P. Fickert, A. Fuchsbichler, D. Silbert, M. Wagner, and S. Arbeiter Role of nuclear bile acid receptor, FXR, in adaptive ABC transporter regulation by cholic and ursodeoxycholic acid in mouse liver, kidney and intestine J Hepatol 39 2003 480 488 (Pubitemid 37204645)
12. T. Kamisako, H. Ogawa, and K. Yamamoto Effect of cholesterol, cholic acid and cholestyramine administration on the intestinal mRNA expressions related to cholesterol and bile acid metabolism in the rat J Gastroenterol Hepatol 22 2007 1832 1837 (Pubitemid 47525090)
13. A.A. Khan, E.C.Y. Chow, R.J. Porte, K.S. Pang, and G.M. Groothuis The role of lithocholic acid in the regulation of bile acid detoxification, synthesis, and transport proteins in rat and human intestine and liver slices Toxicol in Vitro 25 2011 80 90
14. +-dependent bile-acid transporter Biochem J 369 2003 23 30 (Pubitemid 36174121)
15. N. Zelcer, K. van de Wetering, R. de Waart, G.L. Scheffer, H.U. Marschall, and P.R. Wielinga Mice lacking Mrp3 (Abcc3) have normal bile salt transport, but altered hepatic transport of endogenous glucuronides J Hepatol 44 2006 768 775
16. S.M. Houten, D.H. Volle, C.L. Cummins, D.J. Manelsdorf, and J. Auwerx In vivo imaging of farnesoid X receptor activity reveals the ileum as the primary bile acid signaling tissue Mol Endocrinol 21 2007 1312 1323 (Pubitemid 46984739)
17. F. Liu, Y. Song, and D. Liu Hydrodynamics-based transfection in animals by systemic administration of plasmid DNA Gene Ther 6 1999 1258 1266 (Pubitemid 29359019)
18. C. Berasain, E.R. García-Trevijano, J. Castillo, E. Erroba, D.C. Lee, and J. Prieto Amphiregulin: an early trigger of liver regeneration in mice Gastroenterology 128 2005 424 432 (Pubitemid 40431094)
19. -/- mice PLoS One 5 12 2010 e15690
20. M.J. Monte, M.C. Martinez-Diez, M.Y. El-Mir, M.E. Mendoza, P. Bravo, and O. Bachs Changes in the pool of bile acids in hepatocyte nuclei during rat liver regeneration J Hepatol 36 2002 534 542 (Pubitemid 34407343)
21. N.S. Nytofte, M.A. Serrano, M.J. Monte, E. Gonzalez-Sanchez, Z. Tumer, and K. Ladefoged A homozygous nonsense mutation (c.214C->A) in the biliverdin reductase alpha gene (BLVRA) results in accumulation of biliverdin during episodes of cholestasis J Med Genet 48 2011 219 225
22. D.J. Shin, J.A. Campos, G. Gil, and T.F. Osborne PGC-1α activates CYP7A1 and bile acid biosynthesis J Biol Chem 278 2003 50047 50052 (Pubitemid 37548841)
23. W.D. Chen, Y.D. Wang, L. Zhang, S. Shiah, M. Wang, and F. Yang Farnesoid X receptor alleviates age-related proliferation defects in regenerating mouse livers by activating forkhead Box m1b transcription Hepatology 51 2010 953 962
24. B.T. Kren, C.M.P. Rodrigues, K.D.R. Setchell, and C.J. Steer Modulation of steady-state messenger RNA levels in the regenerating rat liver with bile acid feeding Liver Transplant 7 2001 321 334 (Pubitemid 32331536)
25. Chen WD, Wang YD, Meng Z, Zhang L, Huang W. Nuclear bile acid receptor FXR in the hepatic regeneration. Biochim Biophys Acta 2010, Epub ahead of print.
26. S. Teng, and M. Piquette-Miller Hepatoprotective role of PXR activation and Mrp3 in cholic acid-induced cholestasis Brit J Pharmacol 151 2007 367 376 (Pubitemid 46842676)
27. A. Inokuchi, E. Hinoshita, Y. Iwamoto, K. Kohno, M. Kuwano, and T. Uchiumi Enhanced expression of the human multidrug resistance protein 3 by bile salt in human enterocytes: a transcriptional control of a plausible bile acid transporter J Biol Chem 276 2001 49822 49829
28. M. Belinsky, P.A. Dawson, I. Shchaveleva, L.J. Bain, R. Wang, and V. Ling Analysis of the in vivo functions of Mrp3 Mol Pharmacol 68 2005 160 168 (Pubitemid 41002955)
29. Y. Kitamura, H. Kusuhara, and Y. Sugiyama Basolateral efflux mediated by multidrug resistance-associated protein 3 (Mrp3/Abcc3) facilitates intestinal absorption of folates in mouse Pharmaceutical Res 27 2010 665 672