Lethal synergism between influenza virus and Streptococcus pneumoniae: Characterization of a mouse model and the role of platelet-activating factor receptor

Journal of Infectious Diseases

Volumn 186, Issue 3, 2002, Pages 341-350

  McCullers, Jonathan A ^a   Rehg, Jerold E ^a  

^a ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 [N (2 METHOXY 3 OCTADECYLCARBAMOYLOXYPROPOXYCARBONYL)ACETAMIDOMETHYL] 1 ETHYLPYRIDINIUM CHLORIDE; THROMBOCYTE ACTIVATING FACTOR RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BACTERIAL VIRULENCE; COMORBIDITY; CONTROLLED STUDY; FEMALE; INFLUENZA; LETHALITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; STREPTOCOCCUS INFECTION; STREPTOCOCCUS PNEUMONIA; VIRUS VIRULENCE;

ANIMALS; DISEASE MODELS, ANIMAL; FEMALE; LUNG; MICE; MICE, INBRED BALB C; ORTHOMYXOVIRIDAE; ORTHOMYXOVIRIDAE INFECTIONS; PLATELET MEMBRANE GLYCOPROTEINS; PNEUMONIA, PNEUMOCOCCAL; PYRIDINIUM COMPOUNDS; RECEPTORS, CELL SURFACE; RECEPTORS, G-PROTEIN-COUPLED; STREPTOCOCCUS PNEUMONIAE;

EID: 0036681856     PISSN: 00221899     EISSN: None     Source Type: Journal    
DOI: 10.1086/341462     Document Type: Article

References (47)

1. The impact of influenza epidemics on hospitalizations
2. The impact of influenza epidemics on mortality: Introducing a severity index
3. A further investigation into influenzo-pneumococcal and influenzo-streptococcal septicaemia
4. Asiatic influenza in the Middle East: An outbreak in a small community
5. Asian influenza
6. Bacteriological and pathological observations on influenza as seen in France during 1918
7. Influenza and its complications
8. Studies on influenza in the pandemic of 1957-58. II. Pulmonary complications of influenza
9. Notes on cases of influenza in a base hospital in Italy
10. Global epidemiology of infectious diseases
11. Bacteriology and histopathology of the respiratory tract and lungs of fatal Asian influenza
12. Adherence of type I Streptococcus pneumoniae to tracheal epithelium of mice infected with influenza A/PR8 virus
13. Surveillance and impact of influenza in the United States
14. The molecular basis of pneumococcal infection: A hypothesis
15. PAf receptor anchors Streptococcus pneumoniae to activated human endothelial cells
16. Acid exposure stimulates the adherence of Streptococcus pneumoniae to cultured human airway epithelial cells: Effects on platelet-activating factor receptor expression
17. The biology of pneumococcal infection
18. Streptococcus pneumoniae anchor to activated human cells by the receptor for platelet-activating factor
19. A kinetic study of immune mediators in the lungs of mice infected with influenza A virus
20. Respiratory viral infection predisposing for bacterial disease: A concise review
21. Effect of lacto-N-neotetraose, asialoganglioside-GM1 and neuraminidase on adherence of otitis media-associated serotypes of Streptococcus pneumoniae to chinchilla tracheal epithelium
22. Adenovirus infection enhances in vitro adherence of Streptococcus pneumoniae
23. Experimental alteration of chinchilla middle ear mucosae by bacterial neuraminidase
24. Changes in the structure of the cell surface carbohydrates of the chinchilla tubotympanum following Streptococcus pneumoniae-induced otitis media
25. Apoptosis: A mechanism of cell killing by influenza A and B viruses
26. Influenza A virus accelerates neutrophil apoptosis and markedly potentiates apoptotic effects of bacteria
27. Neutrophil deactivation by influenza A virus: Role of hemagglutinin binding to specific sialic acid-bearing cellular proteins
28. Influenza A virus-induced polymorphonuclear leukocyte dysfunction in the pathogenesis of experimental pneumococcal otitis media
29. Effect of virus infection on the inflammatory response: Depression of macrophage accumulation in influenza-infected mice
30. Pulmonary antibacterial defenses during mild and severe influenza virus infection
31. Role of Staphylococcus protease in the development of influenza pneumonia
32. Synergistic role of staphylococcal proteases in the induction of influenza virus pathogenicity
33. The role of proteolytic cleavage of viral glycoproteins in the pathogenesis of influenza virus infections
34. A mouse model of dual infection with influenza virus and Streptococcus pneumoniae
35. CV-6209, a highly potent antagonist of platelet activating factor in vitro and in vivo
36. The susceptibility of swine to the virus of human influenza
37. Combined infection of mice with H. influenzae and influenza virus by the intranasal route
38. Sulfonamide chemotherapy of combined infection with influenza virus and bacteria
39. Otitis media: The chinchilla model
40. Molecular pathogenesis of pneumococcal pneumonia
41. Pathogenesis of pneumococcal pneumonia
42. Pathogenesis of pneumococcal infection
43. Oligosaccharides interfere with the establishment and progression of experimental pneumococcal pneumonia
44. C3 as substrate for adhesion of Streptococcus pneumoniae
45. The polymeric immunoglobulin receptor translocates pneumococci across human nasopharyngeal epithelial cells
46. Pathogenesis of pneumococcal pneumonia