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Volumn 2, Issue 3, 2011, Pages 240-246

Cellular and molecular effects of thiazolidinediones on bone cells: A review

Author keywords

Diabetes mellitus; Osteoblast; Osteoclast; Osteocyte; Ppary; Thiazolidinediones

Indexed keywords

ENGLITAZONE; GLITAZONE DERIVATIVE; LOBEGLITAZONE; NETOGLITAZONE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PIOGLITAZONE; ROSIGLITAZONE; TROGLITAZONE;

EID: 84855957644     PISSN: None     EISSN: 21524114     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (8)

References (49)
  • 1
    • 60449089649 scopus 로고    scopus 로고
    • Medical management of hyperglycemia in type 2 diabetes: A consensus algorithm for the initiation and adjustment of therapy: A consensus statement of the American Diabetes Association and the European Association for the Study of Diabetes
    • Nathan DM, Buse JB, Davidson MB, Ferrannini E, Holman RR, Sherwin R and Zinman B. Medical management of hyperglycemia in type 2 diabetes: a consensus algorithm for the initiation and adjustment of therapy: a consensus statement of the American Diabetes Association and the European Association for the Study of Diabetes. Diabetes Care 2009; 32: 193-203.
    • (2009) Diabetes Care , vol.32 , pp. 193-203
    • Nathan, D.M.1    Buse, J.B.2    Davidson, M.B.3    Ferrannini, E.4    Holman, R.R.5    Sherwin, R.6    Zinman, B.7
  • 4
    • 70349641696 scopus 로고    scopus 로고
    • The risk of fractures associated with thia-zolidinediones: A self-controlled case-series study
    • Douglas IJ, Evans SJ, Pocock S and Smeeth L. The risk of fractures associated with thia-zolidinediones: a self-controlled case-series study. PLoS Med 2009; 6: e1000154.
    • (2009) PLoS Med , vol.6
    • Douglas, I.J.1    Evans, S.J.2    Pocock, S.3    Smeeth, L.4
  • 7
    • 0036007025 scopus 로고    scopus 로고
    • PPARgamma knockdown by engineered transcription factors: Exogenous PPARgamma2 but not PPARgamma1 reactivates adipogenesis
    • Ren D, Collingwood TN, Rebar EJ, Wolffe AP and Camp HS. PPARgamma knockdown by engineered transcription factors: exogenous PPARgamma2 but not PPARgamma1 reactivates adipogenesis. Genes Dev 2002; 16: 27-32.
    • (2002) Genes Dev , vol.16 , pp. 27-32
    • Ren, D.1    Collingwood, T.N.2    Rebar, E.J.3    Wolffe, A.P.4    Camp, H.S.5
  • 9
    • 77954244708 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma (PPARgamma): Is the genomic activity the only answer?
    • Luconi M, Cantini G and Serio M. Peroxisome proliferator-activated receptor gamma (PPARgamma): Is the genomic activity the only answer? Steroids 2010; 75: 585-594.
    • (2010) Steroids , vol.75 , pp. 585-594
    • Luconi, M.1    Cantini, G.2    Serio, M.3
  • 11
    • 0032540325 scopus 로고    scopus 로고
    • Oxidized LDL regulates macro-phage gene expression through ligand activation of PPARgamma
    • Nagy L, Tontonoz P, Alvarez JG, Chen H and Evans RM. Oxidized LDL regulates macro-phage gene expression through ligand activation of PPARgamma. Cell 1998; 93: 229-240.
    • (1998) Cell , vol.93 , pp. 229-240
    • Nagy, L.1    Tontonoz, P.2    Alvarez, J.G.3    Chen, H.4    Evans, R.M.5
  • 12
    • 0028972025 scopus 로고
    • 15-Deoxy-delta 12, 14-prostaglandin J2 is a ligand for the adipocyte determination factor PPAR gamma
    • Forman BM, Tontonoz P, Chen J, Brun RP, Spiegelman BM and Evans RM. 15-Deoxy-delta 12, 14-prostaglandin J2 is a ligand for the adipocyte determination factor PPAR gamma. Cell 1995; 83: 803-812.
    • (1995) Cell , vol.83 , pp. 803-812
    • Forman, B.M.1    Tontonoz, P.2    Chen, J.3    Brun, R.P.4    Spiegelman, B.M.5    Evans, R.M.6
  • 13
    • 0028972026 scopus 로고
    • A prostaglandin J2 metabolite binds peroxisome proliferator-activated receptor gamma and promotes adi-pocyte differentiation
    • Kliewer SA, Lenhard JM, Willson TM, Patel I, Morris DC and Lehmann JM. A prostaglandin J2 metabolite binds peroxisome proliferator-activated receptor gamma and promotes adi-pocyte differentiation. Cell 1995; 83: 813-819.
    • (1995) Cell , vol.83 , pp. 813-819
    • Kliewer, S.A.1    Lenhard, J.M.2    Willson, T.M.3    Patel, I.4    Morris, D.C.5    Lehmann, J.M.6
  • 15
    • 0029016829 scopus 로고
    • An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor gamma (PPAR gamma)
    • Lehmann JM, Moore LB, Smith-Oliver TA, Wilki-son WO, Willson TM and Kliewer SA. An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor gamma (PPAR gamma). J Biol Chem 1995; 270: 12953-12956.
    • (1995) J Biol Chem , vol.270 , pp. 12953-12956
    • Lehmann, J.M.1    Moore, L.B.2    Smith-Oliver, T.A.3    Wilki-Son, W.O.4    Willson, T.M.5    Kliewer, S.A.6
  • 17
    • 34748875916 scopus 로고    scopus 로고
    • Diabetes drug pioglitazone (Actos): Risk of fracture
    • Meymeh RH and Wooltorton E. Diabetes drug pioglitazone (Actos): risk of fracture. CMAJ 2007; 177: 723-724.
    • (2007) CMAJ , vol.177 , pp. 723-724
    • Meymeh, R.H.1    Wooltorton, E.2
  • 19
    • 34147154970 scopus 로고    scopus 로고
    • The peroxisome proliferator-activated receptor-gamma agonist rosiglitazone decreases bone formation and bone mineral density in healthy postmeno-pausal women: A randomized, controlled trial
    • Grey A, Bolland M, Gamble G, Wattie D, Horne A, Davidson J and Reid IR. The peroxisome proliferator-activated receptor-gamma agonist rosiglitazone decreases bone formation and bone mineral density in healthy postmeno-pausal women: a randomized, controlled trial. J Clin Endocrinol Metab 2007; 92: 1305-1310.
    • (2007) J Clin Endocrinol Metab , vol.92 , pp. 1305-1310
    • Grey, A.1    Bolland, M.2    Gamble, G.3    Wattie, D.4    Horne, A.5    Davidson, J.6    Reid, I.R.7
  • 20
    • 34548800490 scopus 로고    scopus 로고
    • Rosiglitazone decreases serum bone-specific alkaline phosphatase activity in postmeno-pausal diabetic women
    • Berberoglu Z, Gursoy A, Bayraktar N, Yazici AC, Bascil Tutuncu N and Guvener Demirag N. Rosiglitazone decreases serum bone-specific alkaline phosphatase activity in postmeno-pausal diabetic women. J Clin Endocrinol Me-tab 2007; 92: 3523-3530.
    • (2007) J Clin Endocrinol Me-tab , vol.92 , pp. 3523-3530
    • Berberoglu, Z.1    Gursoy, A.2    Bayraktar, N.3    Yazici, A.C.4    Bascil, T.N.5    Guvener, D.N.6
  • 26
    • 36849034568 scopus 로고    scopus 로고
    • PPAR-gamma regulates osteoclastogenesis in mice
    • Wan Y, Chong LW and Evans RM. PPAR-gamma regulates osteoclastogenesis in mice. Nat Med 2007; 13: 1496-1503.
    • (2007) Nat Med , vol.13 , pp. 1496-1503
    • Wan, Y.1    Chong, L.W.2    Evans, R.M.3
  • 27
    • 77956408841 scopus 로고    scopus 로고
    • PGC1beta mediates PPARgamma activation of osteoclastogenesis and rosiglitazone-induced bone loss
    • Wei W, Wang X, Yang M, Smith LC, Dechow PC, Sonoda J, Evans RM and Wan Y. PGC1beta mediates PPARgamma activation of osteoclastogenesis and rosiglitazone-induced bone loss. Cell Metab 2010; 11: 503-516.
    • (2010) Cell Metab , vol.11 , pp. 503-516
    • Wei, W.1    Wang, X.2    Yang, M.3    Smith, L.C.4    Dechow, P.C.5    Sonoda, J.6    Evans, R.M.7    Wan, Y.8
  • 29
    • 77954564230 scopus 로고    scopus 로고
    • Bone marrow-derived mesenchymal stem cells and the tumor microenvironment
    • Bergfeld SA and DeClerck YA. Bone marrow-derived mesenchymal stem cells and the tumor microenvironment. Cancer Metastasis Rev 2010; 29: 249-261.
    • (2010) Cancer Metastasis Rev , vol.29 , pp. 249-261
    • Bergfeld, S.A.1    Declerck, Y.A.2
  • 30
    • 0029847076 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor-gamma activation by thiazolidinediones induces adipogenesis in bone marrow stromal cells
    • Gimble JM, Robinson CE, Wu X, Kelly KA, Rodriguez BR, Kliewer SA, Lehmann JM and Morris DC. Peroxisome proliferator-activated receptor-gamma activation by thiazolidinediones induces adipogenesis in bone marrow stromal cells. Mol Pharmacol 1996; 50: 1087-1094.
    • (1996) Mol Pharmacol , vol.50 , pp. 1087-1094
    • Gimble, J.M.1    Robinson, C.E.2    Wu, X.3    Kelly, K.A.4    Rodriguez, B.R.5    Kliewer, S.A.6    Lehmann, J.M.7    Morris, D.C.8
  • 31
    • 33745839778 scopus 로고    scopus 로고
    • Transient suppression of PPARgamma directed ES cells into an osteoblastic lineage
    • Yamashita A, Takada T, Nemoto K, Yamamoto G and Torii R. Transient suppression of PPARgamma directed ES cells into an osteoblastic lineage. FEBS Lett 2006; 580: 4121-4125.
    • (2006) FEBS Lett , vol.580 , pp. 4121-4125
    • Yamashita, A.1    Takada, T.2    Nemoto, K.3    Yamamoto, G.4    Torii, R.5
  • 32
    • 79952108945 scopus 로고    scopus 로고
    • The role of PPARgamma for the osteoblastic differentiation
    • Viccica G, Francucci CM and Marcocci C. The role of PPARgamma for the osteoblastic differentiation. J Endocrinol Invest 2010; 33: 9-12.
    • (2010) J Endocrinol Invest , vol.33 , pp. 9-12
    • Viccica, G.1    Francucci, C.M.2    Marcocci, C.3
  • 33
    • 0036090467 scopus 로고    scopus 로고
    • Divergent effects of selective peroxisome prolifera-tor-activated receptor-gamma 2 ligands on adipocyte versus osteoblast differentiation
    • Lecka-Czernik B, Moerman EJ, Grant DF, Leh-mann JM, Manolagas SC and Jilka RL. Divergent effects of selective peroxisome prolifera-tor-activated receptor-gamma 2 ligands on adipocyte versus osteoblast differentiation. Endocrinology 2002; 143: 2376-2384.
    • (2002) Endocrinology , vol.143 , pp. 2376-2384
    • Lecka-Czernik, B.1    Moerman, E.J.2    Grant, D.F.3    Leh-Mann, J.M.4    Manolagas, S.C.5    Jilka, R.L.6
  • 36
    • 0017642753 scopus 로고
    • The cellular basis of bone turnover and bone loss: A rebuttal of the osteocytic resorption--bone flow theory
    • Parfitt AM. The cellular basis of bone turnover and bone loss: a rebuttal of the osteocytic resorption--bone flow theory. Clin Orthop Relat Res 1977; 236-247.
    • (1977) Clin Orthop Relat Res , pp. 236-247
    • Parfitt, A.M.1
  • 37
    • 12344255130 scopus 로고    scopus 로고
    • Rosiglitazone impacts negatively on bone by promoting osteoblast/ osteocyte apoptosis
    • Soroceanu MA, Miao D, Bai XY, Su H, Goltz-man D and Karaplis AC. Rosiglitazone impacts negatively on bone by promoting osteoblast/ osteocyte apoptosis. J Endocrinol 2004; 183: 203-216.
    • (2004) J Endocrinol , vol.183 , pp. 203-216
    • Soroceanu, M.A.1    Miao, D.2    Bai, X.Y.3    Su, H.4    Goltz-Man, D.5    Karaplis, A.C.6
  • 38
    • 77954798515 scopus 로고    scopus 로고
    • Thiazolidinediones induce osteocyte apoptosis and increase sclerostin expression
    • Mabilleau G, Mieczkowska A and Edmonds ME. Thiazolidinediones induce osteocyte apoptosis and increase sclerostin expression. Diabet Med 2010; 27: 925-932.
    • (2010) Diabet Med , vol.27 , pp. 925-932
    • Mabilleau, G.1    Mieczkowska, A.2    Edmonds, M.E.3
  • 39
    • 24344455975 scopus 로고    scopus 로고
    • Estrogen receptor alpha binds to peroxisome proliferator-activated receptor response element and negatively interferes with perox-isome proliferator-activated receptor gamma signaling in breast cancer cells
    • Bonofiglio D, Gabriele S, Aquila S, Catalano S, Gentile M, Middea E, Giordano F and Ando S. Estrogen receptor alpha binds to peroxisome proliferator-activated receptor response element and negatively interferes with perox-isome proliferator-activated receptor gamma signaling in breast cancer cells. Clin Cancer Res 2005; 11: 6139-6147.
    • (2005) Clin Cancer Res , vol.11 , pp. 6139-6147
    • Bonofiglio, D.1    Gabriele, S.2    Aquila, S.3    Catalano, S.4    Gentile, M.5    Middea, E.6    Giordano, F.7    Ando, S.8
  • 43
    • 33645357530 scopus 로고    scopus 로고
    • Nutrition-related peptides and bone homeostasis
    • Reid IR, Cornish J and Baldock PA. Nutrition-related peptides and bone homeostasis. J Bone Miner Res 2006; 21: 495-500.
    • (2006) J Bone Miner Res , vol.21 , pp. 495-500
    • Reid, I.R.1    Cornish, J.2    Baldock, P.A.3
  • 44
    • 0029906854 scopus 로고    scopus 로고
    • Insulin increases histomorphometric indices of bone formation In vivo
    • Cornish J, Callon KE and Reid IR. Insulin increases histomorphometric indices of bone formation In vivo. Calcif Tissue Int 1996; 59: 492-495.
    • (1996) Calcif Tissue Int , vol.59 , pp. 492-495
    • Cornish, J.1    Callon, K.E.2    Reid, I.R.3
  • 45
    • 33846412672 scopus 로고    scopus 로고
    • Activation of perox-isome proliferator-activated receptor gamma (PPARgamma) by rosiglitazone suppresses components of the insulin-like growth factor regulatory system in vitro and in vivo
    • Lecka-Czernik B, Ackert-Bicknell C, Adamo ML, Marmolejos V, Churchill GA, Shockley KR, Reid IR, Grey A and Rosen CJ. Activation of perox-isome proliferator-activated receptor gamma (PPARgamma) by rosiglitazone suppresses components of the insulin-like growth factor regulatory system in vitro and in vivo. Endocrinology 2007; 148: 903-911.
    • (2007) Endocrinology , vol.148 , pp. 903-911
    • Lecka-Czernik, B.1    Ackert-Bicknell, C.2    Adamo, M.L.3    Marmolejos, V.4    Churchill, G.A.5    Shockley, K.R.6    Reid, I.R.7    Grey, A.8    Rosen, C.J.9
  • 46
    • 0031741159 scopus 로고    scopus 로고
    • Systemic administration of amylin increases bone mass, linear growth, and adiposity in adult male mice
    • Cornish J, Callon KE, King AR, Cooper GJ and Reid IR. Systemic administration of amylin increases bone mass, linear growth, and adiposity in adult male mice. Am J Physiol 1998; 275: E694-699.
    • (1998) Am J Physiol , vol.275
    • Cornish, J.1    Callon, K.E.2    King, A.R.3    Cooper, G.J.4    Reid, I.R.5
  • 47
    • 53049098128 scopus 로고    scopus 로고
    • Dissociation of antihyperglycaemic and adverse effects of partial perioxisome prolifera-tor-activated receptor (PPAR-gamma) agonist balaglitazone
    • Larsen PJ, Lykkegaard K, Larsen LK, Fleckner J, Sauerberg P, Wassermann K and Wulff EM. Dissociation of antihyperglycaemic and adverse effects of partial perioxisome prolifera-tor-activated receptor (PPAR-gamma) agonist balaglitazone. Eur J Pharmacol 2008; 596: 173-179.
    • (2008) Eur J Pharmacol , vol.596 , pp. 173-179
    • Larsen, P.J.1    Lykkegaard, K.2    Larsen, L.K.3    Fleckner, J.4    Sauerberg, P.5    Wassermann, K.6    Wulff, E.M.7
  • 48
    • 0032484224 scopus 로고    scopus 로고
    • A potent antidiabetic thiazolidinedione with unique peroxisome proliferator-activated receptor gamma-activating properties
    • Reginato MJ, Bailey ST, Krakow SL, Minami C, Ishii S, Tanaka H and Lazar MA. A potent antidiabetic thiazolidinedione with unique peroxisome proliferator-activated receptor gamma-activating properties. J Biol Chem 1998; 273: 32679-32684.
    • (1998) J Biol Chem , vol.273 , pp. 32679-32684
    • Reginato, M.J.1    Bailey, S.T.2    Krakow, S.L.3    Minami, C.4    Ishii, S.5    Tanaka, H.6    Lazar, M.A.7
  • 49
    • 0030062325 scopus 로고    scopus 로고
    • The structure-activity relationship between peroxisome pro-liferator-activated receptor gamma agonism and the antihyperglycemic activity of thia-zolidinediones
    • Willson TM, Cobb JE, Cowan DJ, Wiethe RW, Correa ID, Prakash SR, Beck KD, Moore LB, Kliewer SA and Lehmann JM. The structure-activity relationship between peroxisome pro-liferator-activated receptor gamma agonism and the antihyperglycemic activity of thia-zolidinediones. J Med Chem 1996; 39: 665-668.
    • (1996) J Med Chem , vol.39 , pp. 665-668
    • Willson, T.M.1    Cobb, J.E.2    Cowan, D.J.3    Wiethe, R.W.4    Correa, I.D.5    Prakash, S.R.6    Beck, K.D.7    Moore, L.B.8    Kliewer, S.A.9    Lehmann, J.M.10


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.