Thiazolidinediones inhibit osteoclast-like cell formation and bone resorption in vitro

Endocrinology

Volumn 140, Issue 11, 1999, Pages 5060-5065

  Okazaki, Ryo ^a   Toriumi, Masaaki ^a   Fukumoto, Seiji ^b   Miyamoto, Masaaki ^c   Fujita, Toshiro ^b   Tanaka, Koshi ^a   Takeuchi, Yasuhiro ^b  

^a TEIKYO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

^c DAIICHI SANKYO CO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

2,4 THIAZOLIDINEDIONE DERIVATIVE; ADIPSIN; ALKALINE PHOSPHATASE; CALCITRIOL; INTERLEUKIN 11; PARATHYROID HORMONE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR; PIOGLITAZONE; ROSIGLITAZONE; THIAZOLIDINE DERIVATIVE; TROGLITAZONE; UNCLASSIFIED DRUG;

ADIPOSE TISSUE CELL; ANIMAL CELL; ARTICLE; BONE MARROW CELL; CELL DIFFERENTIATION; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; ENZYME ACTIVITY; HORMONE ACTION; MALE; MOUSE; NONHUMAN; OSTEOCLAST; OSTEOLYSIS; PRIORITY JOURNAL; PROTEIN EXPRESSION;

EID: 0033303538     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/endo.140.11.7116     Document Type: Article

References (37)

1. Osteogenic stem cells and the stromal system of bone and marrow
2. Clonal osteogenic cell lines express myogenic and adipocytic developmental potential
3. Human osteogenic protein-1 induces chondroblastic, osteoblastic, and/or aipocytic differentiation of clonal murine target cells
4. Marrow stromal cells as stem cells for nonhematopoietic tissues
5. Modulation of osteoclast differentiation
6. Osteoporosis and the replacement of cell populations of the marrow by adipose tissue
7. Changes in trabecular bone, hematopoiesis and bone marrow vessels in aplastic anemia, primary osteoporosis, and old age: A comparative histomorphometric study
8. PPAR-γ: Adipogenic regulator and thiazolidinedione receptor
9. A prostaglandin J2 metabolite binds peroxisome proliferator-activated receptory and promotes adipocyte differentiation
10. An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor g (PPARγ)
11. Stimulation of adipogenesis in fibroblasts by PPARγ2, a lipid-activated transcription factor
12. 15'-Deoxy-Δ12,14-prostaglandin J2 is a ligand for the adipocyte determination factor PPARγ
13. Peroxisome proliferator-activated receptor-γ activation by thiazolidinediones induces adipogenesis in bone marrow stromal cells
14. Transdifferentiation of myoblasts by the adipogenic transcription factors PPARγ and C/EBPα
15. Metabolic improvement of poorly-controlled non-insulin-dependent diabetes mellitus (NIDDM) decreases bone turnover
16. 3 on the formation and function of osteoclastic cells
17. A simple method to assess osteoclast-mediated bone resorption using unfractionated bone cells
18. Differentiation and cell surface expression of transforming growth factor-β receptors are regulated by interaction with matrix collagen in murine osteoblastic cells
19. Transforming growth factor-β and forskolin increase all classes of insulin-like growth factor-I transcripts in normal human osteoblast-like cells
20. Interleukin-11: A new cytokine critical for osteoclast development
21. Regulation of bone marrow stromal cell differentiation by cytokines whose receptors share the gp130 protein
22. Osteoprotegerin: A novel secreted protein involved in the regulation of bone density
23. Osteoclast differentiation factor is a ligand for osteoprotegerin/osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKL
24. Identity of osteoclastogenesis inhibitory factor (OCIF) and osteoprotegerin (OPG): A mechanism by which OPG/OCIF inhibits osteoclastogenesis in vitro
25. Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation
26. Osteotropic agents regulate the expression of osteoclast differentiation factor and osteoprotegerin in osteoblastic stromal cells
27. Human trabecular bone cells are able to express both osteoblastic and adipocytic phenotype: Implication for osteopenic disorders
28. The function of adipocytes in the bone marrow stroma: An update
29. Osteoblastic gene expression during adipogenesis in hematopoietic supporting murine bone marrow stromal cells
30. Murine bone marrow stromally derived BMS2 adipocytes support differentiation and function of osteoclast-like cells in vitro
31. Bone-resorbing cells
32. Interleukin-11: A novel stroma-derived cytokine
33. PPAR-γ agonists inhibit production of monocyte inflammatory cytokines
34. Isolation of the human peroxisome proliferator activated receptor γ cDNA: Expression in hematopoietic cells and chromosomal mapping
35. PPARγ promotes monocyte/macrophage differentiation and uptake of oxidized LDL
36. 3 inhibits adipocyte differentiation and gene expression in murine bone marrow stromal cell clones and primary cultures