Yeasts as a Tool for Heterologous Gene Expression

Methods in Molecular Biology

Volumn 824, Issue , 2012, Pages 359-370

  Mokdad Gargouri, Raja ^a   Abdelmoula Soussi, Salma ^a   Hadiji Abbès, Nadia ^a   Amor, Ines Yacoubi Hadj ^a   Borchani Chabchoub, Istabrak ^a   Gargouri, Ali ^b  

^a CENTRE DE BIOTECHNOLOGIE DE SFAX   (Tunisia)

^b Medicina UANL   (Mexico)

Author keywords

HBsAg; Heterologous expression; Pichia pastoris; Saccharomyces cerevisiae; Tumor suppressor gene P53

Indexed keywords

ALDEHYDE OXIDASE; AOX1 PROTEIN, HUMAN; GAL10 PROTEIN, S CEREVISIAE; HEPATITIS B SURFACE ANTIGEN; PROTEIN P53; RECOMBINANT PROTEIN; SACCHAROMYCES CEREVISIAE PROTEIN; TRANSACTIVATOR PROTEIN;

ARTICLE; BIOSYNTHESIS; BIOTECHNOLOGY; CHEMISTRY; CULTURE MEDIUM; GENE EXPRESSION REGULATION; GENE VECTOR; GENETICS; HUMAN; METABOLISM; METHODOLOGY; PHYSIOLOGY; PICHIA; POLYACRYLAMIDE GEL ELECTROPHORESIS; SACCHAROMYCES CEREVISIAE; WESTERN BLOTTING;

ALDEHYDE OXIDASE; BIOTECHNOLOGY; BLOTTING, WESTERN; CULTURE MEDIA; ELECTROPHORESIS, POLYACRYLAMIDE GEL; GENE EXPRESSION REGULATION, FUNGAL; GENETIC VECTORS; HEPATITIS B SURFACE ANTIGENS; HUMANS; PICHIA; RECOMBINANT PROTEINS; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; TRANS-ACTIVATORS; TUMOR SUPPRESSOR PROTEIN P53;

EUKARYOTA; PICHIA PASTORIS; SACCHAROMYCES CEREVISIAE;

EID: 84855939269     PISSN: 10643745     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-61779-433-9_18     Document Type: Article

References (27)

1. Romanos M.A., Scorer C.A., Clare J.J. (1992) Foreign gene expression in yeast. Yeast, 8, 423-488.
2. Buckholz R.G., Gleeson M.A. (1991) Yeast systems for the commercial production of heterologous proteins. Biotechnology (N Y). 9, 1067-1072.
3. Sudbery P. E. (1996) The expression of recombinant proteins in yeasts. Cur Op Biotech 517-524. (Pubitemid 26381754)
4. Robinson A., Hines V., Wittrup K. (1994) Protein disulfi de isomerase overexpression increases secretion of foreign proteins in Saccharomyces cerevisiae. Biotechnology (NY) 12, 381-384.
5. Wentz A.E., Shusta E.V. (2007) A novel highthroughput screen reveals yeast genes that increase secretion of heterologous proteins. Appl Environ Microbiol 73, 1189-1198.
6. Wentz A.E., Shusta E.V. (2008) Enhanced secretion of heterologous proteins from yeast by overexpression of ribosomal subunit RPP0. Biotechnol Prog 24, 748-756. (Pubitemid 351832733)
7. Idiris A., Tohda H., Kumagai H., Takegawa K. (2010) Engineering of protein secretion in yeast: strategies and impact on protein production. Appl Microbiol Biotechnol 86, 403-417.
8. Cereghino J. L., Cregg J.M. (2000) Heterologous protein expression in the methylotrophic yeast Pichia pastoris, FEMS Microbiol. Rev. 24, 45-66. (Pubitemid 30047114)
9. Macauley-Patrick S., Fazenda M. L., McNeil B., Harvey L. M. (2005) Heterologous protein production using the Pichia pastoris expression system. Yeast 22, 249-270. (Pubitemid 40528349)
10. Cregg J.M., Cereghino J. L., Shi J., Higgins D.R. (2000) Recombinant protein expression in Pichia pastoris. Mol. Biotechnol. 16, 23-52.
11. Gellissen G., Kunze G., Gaillardin C., Cregg J.M., Berardi E., Veenhuis M., van der Klei I. (2005) New yeast expression platforms based on methylotrophic Hansenula polymorpha and Pichia pastoris and on dimorphic Arxula adeninivorans and Yarrowia lipolytica : A comparison. FEMS Yeast Res 5, 1079-1096. (Pubitemid 41564061)
12. Hollenberg C.P., Gellissent G. 2009) Production of recombinant proteins by methylotrophic yeasts Biotechnology Advances 27 297-306
13. Levine A.J. (1997) P53 the cellular gatekeeper for the growth and division. Cell 88, 323-331. (Pubitemid 27131374)
14. Lane D.P. (1992) P53, guardian of the genome Nature 358, 15-16.
15. Guimaraes D.P., Hainaut P. (2002) TP53: A key gene in human cancer Biochimie 84 83-93. (Pubitemid 34477096)
16. Hammel P., Boissier B., Chaumette M.T., Piedbois P., Rotman N., Kouyoumdjian J.C., et al. (2000) Detection and monitoring of serum p53 antibodies in patients with colorectal cancer. Gut 40, 356-361.
17. Kuli A, Sirotkovi -Skerlev M, Jelisavac-Cosi S, Herceg D, Kovac Z, Vrbanec D. (2010) Anti-p53 antibodies in serum: relationship to tumor biology and prognosis of breast cancer patients. Med Oncol. 27, 887-893.
18. Flaman J. M, Frebourg T., Moreau V., Charbonnier F., Martin C., Chappuis P. et al. (1995) A simple p53 functional assay for screening cell lines, blood, and tumors. Proc Natl Acad Sci USA 92, 3963-3967.
19. Nigro J., Sikorski R., Reed S., Vogelstein B. (1992) Human p53 and CDC2Hs genes combine to inhibit the proliferation of Saccharomyces cerevisiae. Mol Cell Biol 12, 1357-1365.
20. Yacoubi-Hadj Amor I., Smaoui K., Chaabene I., Mabrouk I., Djemal L., Elleuch H. et al. (2008). Human p53 induces cell death and downregulates thioredoxin expression in Saccharomyces cerevisiae. FEMS Yeast Res 8, 1254-1262.
21. State of the World's Vaccines and Immunization, WHO/UNICEF Bulletin, Geneva, 1996.
22. Rogers S.A. Dienstag JL., Liang T.J. (1997) Hepatitis B virus-clinical disease, prevention and therapy, in: R.A. Willson (Ed.), Viral Hepatitis, Dekker, New York, 119-146.
23. Hitzeman R.A., Chen C.Y., Hagie F.E., Patzer E.J., Liu C.C., Estell D.A. et al. (1983) Expression of hepatitis B surface antigen gene in yeast. Nucleic Acids Res. 11, 2745-2763.
24. Imamura T., Araki M., Miyanohara A., Nakao J., Yonemura H., Ohtomo N., Matsubara K. (1987) Expression of hepatitis B virus middle and large surface antigen genes in Saccharomyces cerevisiae. J. Virol. 61, 3543-3549. (Pubitemid 17156488)
25. Vassileva A., Chugh D.A, Swaminathan S., Khanna N. (2001) Expression of hepatitis B surface antigen in the methylotrophic yeast Pichia pastoris using the GAP promoter, J. Biotechnol. 88, 21-35. (Pubitemid 32480115)
26. Hadiji-Abbes N., Borchani-Chabchoub I., Triki H., Ellouz R., Gargouri A., Mokdad-Gargouri R. (2009). Expression of HBsAg and preS2-S protein in different yeast based system: A comparative analysis. Prot Exp & Purif. 66, 131-137.
27. Abdelmoula-Souissi S., Rekik L., Gargouri A., Mokdad-Gargouri R. (2007) High-level expression of human tumour suppressor P53 in the methylotrophic yeast: Pichia pastoris. Prot. Exp Purif. 54, 283-288. (Pubitemid 46795569)