Heterologous expression of human cytochromes P450 2D6 and CYP3A4 in escherichia coli and their functional characterization

Protein Journal

Volumn 30, Issue 8, 2011, Pages 581-591

  Pan, Yan ^a   Abd Rashid, Badrul Amini ^b   Ismail, Zakiah ^b   Ismail, Rusli ^c   Mak, Joon Wah ^a   Ong, Chin E ^d  

^a INTERNATIONAL MEDICAL UNIVERSITY   (Malaysia)

^b INSTITUTE FOR MEDICAL RESEARCH   (Malaysia)

^c INSTITUTE FOR RESEARCH IN MOLECULAR MEDICINE INFORMM   (Malaysia)

^d MONASH UNIVERSITY MALAYSIA   (Malaysia)

Author keywords

Cytochromes P450; Dextromethorphan O demethylation; HPLC; Protein expression; Testosterone 6beta; hydroxylation

Indexed keywords

CYTOCHROME P450 2D6; CYTOCHROME P450 3A4; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE FERRIHEMOPROTEIN REDUCTASE;

AMINO TERMINAL SEQUENCE; ARTICLE; BACTERIAL MEMBRANE; CATALYSIS; ENZYME ACTIVITY; ESCHERICHIA COLI; HETEROLOGOUS EXPRESSION; HUMAN; MOLECULAR CLONING; NONHUMAN; PROTEIN FUNCTION; SEQUENCE ANALYSIS;

BACTERIA (MICROORGANISMS); BOVINAE; ESCHERICHIA COLI;

EID: 84855938911     PISSN: 15723887     EISSN: 18758355     Source Type: Journal    
DOI: 10.1007/s10930-011-9365-6     Document Type: Article

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