Galantamine elicits neuroprotection by inhibiting iNOS, NADPH oxidase and ROS in hippocampal slices stressed with anoxia/reoxygenation

Neuropharmacology

Volumn 62, Issue 2, 2012, Pages 1082-1090

  Egea, J ^a,b,d   Martin De Saavedra M D ^a,b   Parada, E ^a,b   Romero, A ^a,b,d   Del Barrio, L ^a,b   Rosa, A O ^a,b   Garcia A G ^a,b,c   Lopez M G ^a,b,d  

^a INSTITUTO TEÓFILO HERNANDO   (Spain)

^b UNIVERSIDAD AUTÓNOMA DE MADRID   (Spain)

^c HOSPITAL UNIVERSITARIO DE LA PRINCESA   (Spain)

^d HOSPITAL UNIVERSITARIO LA PAZ IDIPAZ   (Spain)

Author keywords

Galantamine; Ischemia; Neuroprotection; ROS

Indexed keywords

GALANTAMINE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; JANUS KINASE 2; NICOTINIC RECEPTOR; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SYNAPTOTAGMIN I;

ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BRAIN ISCHEMIA; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; DRUG EFFICACY; ENZYME INHIBITION; ENZYME SYNTHESIS; HIPPOCAMPAL CA1 REGION; HIPPOCAMPAL CA3 REGION; IN VITRO STUDY; MALE; NERVE CELL NECROSIS; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REOXYGENATION; REPERFUSION;

ANIMALS; ANOXIA; CELL DEATH; DOSE-RESPONSE RELATIONSHIP, DRUG; GALANTAMINE; HIPPOCAMPUS; JANUS KINASE 2; MALE; NADPH OXIDASE; NEUROPROTECTIVE AGENTS; NITRIC OXIDE SYNTHASE TYPE II; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES; RECEPTORS, NICOTINIC;

EID: 84855935224     PISSN: 00283908     EISSN: 18737064     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2011.10.022     Document Type: Article

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